In vitro evaluation of the immunomodulatory and antibacterial activities of calcitriol (1,25-dihydroxy-vitamin D3) as a potential application for aerobic vaginitis treatment - prel... by Anna Tomusiak-Plebanek, Grażyna Więcek, Edyta Golińska, Magdalena Strus

“…However, conclusions regarding the potential use of calcitriol in the treatment of AV require further confirmation in in vivo studies as well as in well-designed clinical trials.…”
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Reengineering of the organizational structure and business processes of investment and construction activities. Their place in the general system of corporate regulation by S. B. Sborshikov, N. V. Lazareva

“…The theoretical basis of the research was a system approach, logistics of regulatory impacts, structural and functional analysis, methods of investment design, strategic and operational management. The information base of the research was the scientific search carried out by the authors earlier, which was reflected in published papers on this subject. …”
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ChatGPT-4 Performance on German Continuing Medical Education—Friend or Foe (Trick or Treat)? Protocol for a Randomized Controlled Trial by Christian Burisch, Abhav Bellary, Frank Breuckmann, Jan Ehlers, Serge C Thal, Timur Sellmann, Daniel Gödde

“…Depending on the results, the potential influence of LLMs such as ChatGPT-4 on CME will be discussed, for example, as part of a SWOT (strengths, weaknesses, opportunities, threats) analysis. MethodsWe designed a randomized controlled trial, in which adult high school students attempt to solve CME tests across six medical specialties in three study arms in total with 18 CME training courses per study arm under different interventional conditions with varying amounts of permitted use of ChatGPT-4. …”
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Association of ambient temperatures with suicide attempts and violence with the future projections under climate change scenarios: a nationwide time-stratified case-crossover study... by Jiwoo Park, Jieun Oh, Whanhee Lee, Yeonsu Kim, Jeong Ho Park, Ho Kim, Seungsik Hwang

“…We performed a two-stage analysis with a time-stratified case-crossover design to evaluate the associations of outdoor temperatures with suicide attempts and violence using historical data (2005–2019). …”
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Attitudes of German General Practitioners Toward eHealth Apps for Dementia Risk Reduction: Qualitative Interview Study by Adrian Schultz, Melanie Luppa, Markus Bleckwenn, Steffi G Riedel-Heller, Andrea Zuelke

“…Prerequisites for the use of eHealth apps for dementia prevention were app characteristics related to design and content. GPs need to address dementia more routinely, assess relevant risk factors, and aid patients in a preventive role. …”
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Serum 25-hydroxyvitamin D level in relation to weight change and the risk of weight gain in adults of normal weight at baseline: the Norwegian HUNT cohort study by Yi-Qian Sun, Yue Chen, Xiao-Mei Mai, Adaline Heitz

“…Objective We sought to investigate the relationship of serum 25-hydroxyvitamin D (25(OH)D) level with weight change and the risk of weight gain in an adult population who had normal weight at baseline and were followed up for 11 years.Design A population-based prospective cohort study.Setting Nord-Trøndelag, Norway.Participants The study included 1501 adults who participated in the second and third surveys of the Nord-Trøndelag Health Study (HUNT2 (1995–1997) and HUNT3 (2006–2008)) and had a normal body mass index ≥18.5 and <25.0 kg/m2 at baseline.Primary and secondary outcome measures Relative weight change (%) was calculated as ((HUNT3 weight−HUNT2 weight)/HUNT2 weight×100). …”
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Incidence and risk factors for mortality of vertebral osteomyelitis: a retrospective analysis using the Japanese diagnosis procedure combination database by Hideo Yasunaga, Hirotaka Chikuda, Kiyohide Fushimi, Hiromasa Horiguchi, Toru Akiyama, Kazuo Saita

“…Objective To examine the incidence of vertebral osteomyelitis (VO) and the clinical features of VO focusing on risk factors for death using a Japanese nationwide administrative database.Design Retrospective observational study.Setting Hospitals adopting the Diagnosis Procedure Combination system during 2007–2010.Participants We identified 7118 patients who were diagnosed with VO (International Classification of Diseases, 10th Revision codes: A18.0, M46.4, M46.5, M46.8, M46.9, M48.9 and M49.3, checked with the detailed diagnoses in each case and all other codes indicating the presence of a specific infection) and hospitalised between July and December, 2007–2010, using the Japanese Diagnosis Procedure Combination database.Main outcome measures The annual incidence of VO was estimated. …”
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Perancangan dan Pembuatan Sistem Informasi Retensi Rekam Medis Rawat Jalan di Puskesmas Jenggawah Kabupaten Jember by Andri Permana Wicaksono, Muhaiminul Aziz, Feby Erawantini, Ida Nurmawati

“…The implementation of retention still aplied manually, caused retention activity did not run effectively and efficiently, and did not in accordance with the times. This study aims to design and creates an outpatient medical record retention information system at Jenggawah Public Health Center. …”
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Conventional endotracheal tubes versus polymer-coated tubes in ventilator-associated pneumonia development: A systematic review and meta-analysis by Oscar Inácio de Mendonça Bisneto, Luanna Paula Garcez de Carvalho Feitoza, Larissa Calixto Hespanhol, Sávio Benvindo Ferreira, Caroline Serafim Dagostin, Roberto Augusto Mazetto Silva Vieira, Lucas Alencar Queiroz, Lucas Chen, Taniela Marli Bes, Ho Yeh Li

“…Thus, this meta-analysis aims to compare conventional endotracheal tubes with those made using materials designed to prevent colonization. Methods: This analysis was conducted according to the PRISMA guidelines. …”
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Depressive symptoms and quality of life among women experiencing infertility: The moderating effect of perceived social support by Minjeong Jo, Hyewon Shin, Angela Kabbe, Shin-Jeong Kim

“…Methods: Utilizing a cross-sectional design, this study analyzed a secondary dataset comprising 186 South Korean women with infertility. …”
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Empowering biomedical learners to navigate FDA regulatory processes and entrepreneurship with a novel interdisciplinary training approach by Philip A. Cola, Philip A. Cola, Tawna L. Mangosh

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Assessment of Antimicrobial Use for Companion Animals in South Korea: Developing Defined Daily Doses and Investigating Veterinarians’ Perception of AMR by Sun-Min Kim, Heyong-Seok Kim, Jong-Won Kim, Kyung-Duk Min

“…The identified factors that affect veterinarians’ prescription practices can also be used to design an effective strategy for promoting appropriate antimicrobial usage.…”
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Strength and Durability Performance of Hybrid Alkaline Clay Brick Waste –Coconut Shell Ash Cement by Victor Kiptoo Mutai, Mike Otieno, Joseph M. Marangu, Fredrick Mulei Mutunga, Najya Muhammed, Festus Ngui

“…Results show that alkali-activated samples exhibited lower sorptivity, Porosity, chloride ingress, and higher compressive strength, oxygen permeability index, and thermal resistance than the cement mix prepared with water. The mix designs 5-1-4, 5-4-1, 3-1-6, and 3-6-1 demonstrated a decreasing optimum performance comparable to OPC in that order. …”
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Short-Term Clinical Outcomes After Anterior Cruciate Ligament Reconstruction In Adolescents During The COVID-19 Pandemic by Adam Weaver, Brandon Ness, Dylan Roman, Nicholas Giampetruzzi, Joshua Cleland

“…The purpose of this study was to determine if short-term clinical outcomes were different in adolescents after ACLR for those who underwent surgery pre-COVID versus during the COVID-19 pandemic timeframe. # Design Retrospective cohort # Methods A retrospective review of records occurred for patients who underwent ACLR with a quadriceps tendon autograft. …”
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Inguinal Lymph Node Dissection for Advanced Stages of Plantar Melanoma in a Low-Income Country by Ollo Roland Somé, Malick Diallo, Damien Konkobo, Nassirou Yabré, Valentin Konségré, Issouf Konaté, Sidy Ka

“…Our study aims to share our experience in ILND for advanced plantar melanomas. Methods and Study Design. Four-year prospective study. Patients. We included all documented cases of advanced stage plantar melanoma with clinically detectable inguinal lymph node metastasis. …”
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Early warning systems (EWSs) for chikungunya, dengue, malaria, yellow fever, and Zika outbreaks: What is the evidence? A scoping review. by Laith Hussain-Alkhateeb, Tatiana Rivera Ramírez, Axel Kroeger, Ernesto Gozzer, Silvia Runge-Ranzinger

“…A scoping review has been undertaken for all 5 diseases to summarize existing evidence of EWS tools in terms of their structural and statistical designs, feasibility of integration and implementation into national surveillance programs, and the users' perspective of their applications.…”
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Risk prediction models for dysphagia after radiotherapy among patients with head and neck cancer: a systematic review and meta-analysis by You Pu, Jin Yang, Lian Shui, Qianlong Tang, Xianqin Zhang, Guangguo Liu

“…Future studies should focus on large sample size and rigorously designed multicenter external validation to improve the reliability and clinical applicability of prediction models for dysphagia after radiotherapy for HNC.Systematic review registrationhttps://www.crd.york.ac.uk/prospero, identifier CRD42024587252.…”
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Biochemical Composition Variation among Southern Ethiopian Arabica Coffee (Coffea arabica L.) Genotypes by Meseret Degefa, Sentayehu Alamerew, Ali Mohammed, Adeba Gemechu

“…Therefore, a nutritional laboratory experiment was carried out at Jimma University College of Agriculture and Veterinary Medicine (JUCAVM). Using the augmented design, a total of 104 entries were examined, including 100 accessions from southern Ethiopia and four standard checks. …”
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Mixed pastures and biological efficiency in buffalo production systems: determinants for a sustainable livestock by Juan Pablo Uzcátegui-Varela, Martha Gloribet Ceballos Ramírez

“…By bringing together the conclusive comments of each scientific instrument consulted, the current philosophy of sustainable development to establish sustainable livestock systems requires in particular: a) designing agroecosystems that favor the increase of biodiversity; b) monitoring key indicators of biological efficiency and including the evaluation of feasibility to implement corrective measures; and c) taking maximum advantage of highly biodiverse or mixed pastures under technical control of grazing to minimize the emission of pollutant gases. …”
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Pre- and Post-Operative Pain Intensity and Physical Activity Levels in Individuals with Acetabular Dysplasia Undergoing Periacetabular Osteotomy: A Prospective Cohort Study by Naif Alrashdi, Robert Motl, Elroy Aguiar, Donald Lein Jr, Suzanne Perumean-Chaney, Michael Ryan, Matthew Ithurburn

“… # Purpose To examine pain recovery and physical activity (PA) before and during the six months after PAO. # Study Design Case series, prospective # Methods Individuals with AD scheduled for PAO were enrolled. …”
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