Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis by Ritin Fernandez, Heidi Green, Arti Muley, Prasad Muley

“…Interpretation: Thiamine supplementation does not affect glycaemic outcomes, however reduces triglycerides while increasing HDL. Multicentre well-designed RCT with higher doses of thiamine and a follow-up period of 1–2 years will provide better evidence.PROSPERO registration number CRD42020170520.…”
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Association between use of sodium-glucose co-transporter-2 inhibitor and the risk of incident dementia: a population-based cohort study by Robert W Platt, Laurent Azoulay, Ying Cui, Christel Renoux, Oriana Hoi Yun Yu, Zarin Abdullah, Chenjie Xia

“…Objectives To assess the association between sodium-glucose co-transporter-2 inhibitor (SGLT-2i) use and the risk of incident dementia compared with dipeptidyl peptidase-4 inhibitors (DPP-4i) use among individuals with type 2 diabetes.Design A population-based retrospective cohort study.Setting The Clinical Practice Research Datalink (CPRD) Aurum database from the UK.Participants Individuals with type 2 diabetes, aged 40 years or older, newly prescribed SGLT-2i or DPP-4i on or after 2013–2021, registered in the CPRD Aurum database.Main outcome measure The primary outcome was incident dementia, and the secondary outcome was incident mild cognitive impairment (MCI). …”
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Differences in prevalence and associated factors of underweight and overweight/obesity according to rural–urban residence strata among women of reproductive age in Bangladesh: evid... by Rajat Das Gupta, Mohammad Rashidul Hashan, Gulam Muhammed Al Kibria, Brendan Day

“…Objectives This study aimed to investigate the differences in prevalence and factors influencing underweight and overweight/obesity stratified by region of residence among women of reproductive age in Bangladesh.Design Secondary analysis of cross-sectional nationwide data.Setting This study used Bangladesh Demographic and Health Survey 2014 data.Participants A weighted sample of 16 478 women of reproductive age (15–49 years) were included in the analysis.Primary and secondary outcome measures Using the Asian-specific cut-off for body mass index, the primary outcome of this study was categorised as: underweight (<18.5 kg/m2), normal weight (18.5 to <23.0) kg/m2 and overweight/obese (≥23.0 kg/m2) stratified according to rural–urban residence.Results More than half of urban women (53%, n=2493) and one-third of rural women (33%, n=3968) were found to be overweight/obese. …”
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Chest CT Scan Features to Predict COVID-19 Patients’ Outcome and Survival by Mohammad-Mehdi Mehrabi Nejad, Aminreza Abkhoo, Faeze Salahshour, Mohammadreza Salehi, Masoumeh Gity, Hamidreza Komaki, Shahriar Kolahi

“…Using a case-control design, we included all laboratory-confirmed COVID-19 patients who were deceased, from June to September 2020, in a tertiary-referral-collegiate hospital and had on-admission chest CT as the case group. …”
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The Effect of Volitional Preemptive Abdominal Contraction on Biomechanical Measures During A Front Versus Back Loaded Barbell Squat by Joseph B. McCormick, Alexander S. Drusch, Darragh J. Lynch, Gesine H. Seeber, Katherine F. Wilford, Troy L. Hooper, Brad S. Allen, Dennis G. O’Connell, Maria J. Mena-Iturriaga, Kinyata J. Cooper, Phillip S. Sizer

“… # Hypothesis/Purpose The purpose of this study was to examine the effects of VPAC performance on trunk muscle and LE biomechanical responses during loaded BackS versus FrontS in healthy subjects. # Study Design Controlled Laboratory Study # Methods Healthy male subjects with the ability to perform a sub-maximal loaded barbell squat lift were recruited. …”
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Effect of PCSK9 Inhibitor on Blood Lipid Levels in Patients with High and Very-High CVD Risk: A Systematic Review and Meta-Analysis by Yue Zhang, Yanrong Suo, Lin Yang, Xiaolu Zhang, Qun Yu, Miao Zeng, Wenlan Zhang, Xijuan Jiang, Yijing Wang

“…We aimed to investigate the effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor on blood lipid levels in patients with high and very-high cardiovascular risk. Design. 14 trials (n = 52,586 patients) comparing treatment with or without PCSK9 inhibitors were retrieved from PubMed and Embase updated to 1st Jun 2021. …”
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Impact of the COVID-19 pandemic on psychotropic prescribing: a systematic review by Nikolaos Mastellos, Marie line El Asmar, Kanika I Dharmayat, Antonio J Vallejo-Vaz, Ryan Irwin, Swettha Mahesarajah

“…This study aims to assess the impact of the COVID-19 pandemic on changes in psychotropic prescribing patterns in adults, as well as differences in prescribing in different healthcare delivery approaches across various geographical contexts.Design and eligibility requirements Systematic review of cohort, interrupted time-series and cross-sectional studies examining prescribing trends for at least one commonly prescribed psychotropic drug during and after COVID-19 in accessing care remotely or face to face between 1 January 2020 and 17 June 2022.Data sources MEDLINE, EMBASE, CINAHL, HMIC and PsycINFO databases were searched in addition to citation chaining of relevant reviews.Extraction and analysis Study screening, data extraction and quality assessment were completed by two independent reviewers. …”
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Community knowledge, perceptions and practices around COVID-19 in Sierra Leone: a nationwide, cross-sectional survey by Maike Winters, Helena Nordenstedt, Mohammad B Jalloh, Paul Sengeh, Nance Webber, Ibrahim Ngobeh, Thomas Samba, Harold Thomas

“…Objectives To assess the public’s knowledge, attitudes and practices about the novel coronavirus in Sierra Leone to inform an evidence-based communication strategy around COVID-19.Design Nationwide, cross-sectional Knowledge, Attitudes and Practices survey.Setting 56 randomly selected communities in all 14 districts in Sierra Leone.Participants 1253 adults aged 18 years and older of which 52% were men.Main outcome measures We calculated proportions of core indicators (awareness, knowledge, risk perception, practices). …”
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Cervical cancer screening by cotesting method for Vietnamese women 25–55 years old: a cost-effectiveness analysis by Hien Thu Bui, Van Nu Hanh Pham, Thang Hong Vu

“…The objective is to provide evidence to inform policy and clinical practice in Vietnam.Design Cost-effectiveness analysis using a Markov model with 1 year cycles to simulate the natural progression of CC.Setting The Vietnamese healthcare system, modelled from the provider’s perspective, with parameters adapted to the local context through expert consultations.Participants A simulated cohort of Vietnamese women aged 25–55 years.Interventions The intervention involved cotesting (cytology and HPV testing) three times at 5 year intervals. …”
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Associations between autistic traits and early ear and upper respiratory signs: a prospective observational study of the Avon Longitudinal Study of Parents and Children (ALSPAC) ge... by Amanda Hall, Dheeraj Rai, Jean Golding, Yasmin Iles-Caven, Steven Gregory, Richard Maw

“…Objective To determine whether early ear and upper respiratory signs are associated with the development of high levels of autistic traits or diagnosed autism.Design Longitudinal birth cohort: Avon Longitudinal Study of Parents and Children (ALSPAC).Setting Area centred on the city of Bristol in Southwest England. …”
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Role of comprehensive geriatric assessment in healthcare of older people in UK care homes: realist review by Claire Goodman, Tom Dening, Neil H Chadborn, Maria Zubair, Lídia Sousa, John R F Gladman, Adam, L Gordon

“…We used realist review to develop a theory-driven account of how CGA works in care homes.Design Realist review.Setting Care homes.Methods The review had three stages: first, interviews with expert stakeholders and scoping of the literature to develop programme theories for CGA; second, iterative searches with structured retrieval and extraction of the literature; third, synthesis to refine the programme theory of how CGA works in care homes.We used the following databases: Medline, CINAHL, Scopus, PsychInfo, PubMed, Google Scholar, Greylit, Cochrane Library and Joanna Briggs Institute.Results 130 articles informed a programme theory which suggested CGA had three main components: structured comprehensive assessment, developing a care plan and working towards patient-centred goals. …”
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Nurse worry as a trigger for rapid response team activation improving outcomes: a retrospective cohort study in non-critical units by Luana L.S. Gentil, Milena S. Nascimento, Michele Jaures, Leonardo P. de Carvalho, Claudia R. Laselva, Simone Brandi

“…However, the observational design of the study does not allow for establishing causal relationships.…”
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Mechanism of Fire Prevention with Liquid Carbon Dioxide and Application of Long-Distance Pressure-Holding Transportation Technology Based on Shallow Buried and Near-Horizontal Goaf... by Naifu Cao, Yuntao Liang

“…After comprehensive analysis of experiments and numerical simulations, appropriate equipment and process flow are selected and designed. Taking the Huojitujing well of Daliuta Coal Mine in Shendong mining area as the industrial test site, an intelligent pressure-holding transportation of liquid CO2 in the 1000 m transportation pipeline was developed. …”
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Using Peer-Learning and Game-Based Instruction for Achieving Long-Lasting Knowledge of Cybersecurity in Primary Schools by Maja Videnovik, Vladimir Trajkovik, Tone Vold, Linda Vibeke Kionig, Ana Madevska Bogdanova, Sonja Filiposka

“…The game-based approach is used to create interactive and engaging learning environments where students design or play games to develop their critical thinking skills and empower their cybersecurity knowledge. …”
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Barriers and enablers to implementing clinical practice guidelines in primary care: an overview of systematic reviews by Tao Wang, Xian-Liang Liu, Jing-Yu (Benjamin) Tan, Isabella Zhao

“…Objectives To identify the barriers and enablers to implementing clinical practice guidelines (CPGs) recommendations in primary care and to provide recommendations that could facilitate the uptake of CPGs recommendations.Design An overview of systematic reviews.Data sources Nine electronic databases (PubMed, Cochrane Library, CINAHL, MEDLINE, PsycINFO, Web of Science, Journals @Ovid Full Text, EMBase, JBI) and three online data sources for guidelines (Turning Research Into Practice, the National Guideline Clearinghouse and the National Institute for Health and Care Excellence) were searched until May 2021.Eligibility criteria Systematic reviews, meta-analyses or other types of systematic synthesis of quantitative, qualitative or mixed-methods studies on the topic of barriers and/or enablers for CPGs implementation in primary care were included.Data extraction and synthesis Two authors independently screened the studies and extracted the data using a predesigned data extraction form. …”
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Construction of novel pJRD215-derived plasmids using chloramphenicol acetyltransferase (cat) gene as a selection marker for Acidithiobacillus caldus. by Rui Wang, Chunmao Lin, Jianqiang Lin, Xin Pang, Xiangmei Liu, Chengjia Zhang, Jianqun Lin, Linxu Chen

“…The P2-cat gene cassette, including a chloramphenicol acetyltransferase gene (cat) from plasmid pACBSR and a promoter (P2) upstream of the tetracycline resistance gene on pBR322, was designed, chloramphenicol acetyltransferase was expressed in A. caldus, and the enzyme activity was assessed. …”
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Company's diversification strategy and crash risk stock prices emphasizing operational slack and management ability by Majid Moradi, Roqaye Talebi, Hamid Reza Pakdaman

“…Such insights open a new avenue for future research to investigate how to reduce the risk of collapse through the strategic design of companies' operations and production. Third, the prevailing consensus among management scholars is that diversification is essential regarding economic performance and risk reduction. …”
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Definitions of Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients: A Systematic Review Protocol by Jean Zhuo Wang, Lindsey Sikora, Peter Farrell, Swapnil Hiremath, Edward G. Clark

“…The secondary objective of this systematic review is to compare rates of HIRRT, according to various definitions used by randomized controlled trials, across different RRT modalities used to treat critically ill patients, with the goal of paving the way toward a common definition of HIRRT for future research. Design: Systematic review and meta-analysis Measurements: The rates of HIRRT, mortality, and renal recovery will be reported according to each definition of HIRRT Patients: Critically-ill adults with acute kidney injury admitted to intensive care units Methods: The search strategy will be developed to identify articles in Medline, MEDLINE In-Process, EMBASE, and Cochrane CENTRAL Registry. …”
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Deep learning model based prediction of vehicle CO2 emissions with eXplainable AI integration for sustainable environment by Gazi Mohammad Imdadul Alam, Sharia Arfin Tanim, Sumit Kanti Sarker, Yutaka Watanobe, Rashedul Islam, M. F. Mridha, Kamruddin Nur

“…Overall, this study contributes to the design of effective strategies for reducing vehicle CO2 emissions and promoting environmental sustainability.…”
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Socioeconomic disparity in stage at cancer diagnosis among patients with type 2 diabetes in Dutch primary care: a cross-sectional study by Geertruida H De Bock, Gijs W D Landman, Nanne Kleefstra, Bert van der Vegt, Sabine Siesling, Klaas H Groenier, Jing de Haan-Du

“…We evaluated the association of SES and cancer stage among patients with type 2 diabetes (T2DM) treated in primary care.Research design and methods This cross-sectional study linked data from the primary care Zwolle Outpatient Diabetes Project Integrating Available Care database for T2DM (n=71 648, 1998–2019) to a cancer registry and personal records database in the Netherlands. …”
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