Correlation between carbapenem susceptibility in Pseudomonas aeruginosa and modified antibiotic heterogeneity index: a multicenter observational study using a surveillance platform by Keisuke Sawada, Takaaki Kato, Shuji Kono, Hiromi Kaneko, Hayato Nakano, Shinobu Inada, Tatsuya Isogawa, Tadahiro Shimizu, Namiko Takahashi, Haruki Takano, Hiroaki Chiba, Makoto Sugimoto, Ryo Inose, Yuichi Muraki, Hideki Araoka

“… Abstract Objective: This study focused on exploring the relationship between antimicrobial use indicators, including the modified antibiotic heterogeneity index (mAHI), and the carbapenem susceptibility in Pseudomonas aeruginosa. Design: Survey-based observational study conducted across multiple facilities. …”
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Impact of the SARS-CoV-2/COVID-19 pandemic on the patient journeys of those with a newly diagnosed paediatric brain tumour in the UK: a qualitative study by Rachel Isba, Donald MacArthur, Liz Brewster, Ibrahim Jalloh, John-Paul Kilday, Kalsoom Akhter, Roland Casson, G A Amos Burke

“…Objectives To explore the impact of the SARS-CoV-2/COVID-19 pandemic on the diagnosis, management and patient journey for children and young people with a newly diagnosed brain tumour in the UK.Design Exploratory qualitative study focused on patient journeys from multiple perspectives, conducted as part of a wider mixed-methods study.Setting Three paediatric oncology tertiary centres in the UK.Participants 10 children and young people with brain tumours (n=6 females, n=4 males), 20 caregivers (n=16 females, n=4 males) and 16 stakeholders (specialist nurses, consultant neurosurgeons and oncologists, and representatives from brain tumour charities) were interviewed between January 2022 and June 2023.Results The paper incorporates multiple perspectives, including those of children and young people, parents/caregivers, clinical staff and charity representatives, to explore the patient journey. …”
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Cerebral tissue oxygen desaturations and increased fractional oxygen extraction events vary by gestational age in preterm infants by M. Mohamed, M. Frasketi, H. Hoffman, M. Elgendy, S. Aly, H. Aly

“…This study examines changes in frequency, duration, and severity of SctO2 desaturation and increased cFTOE with GA. Study design: The lower limit of normal SctO2, the event threshold, was calculated using a tolerance interval method with 95% confidence interval (CI) and 90% probability. …”
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Female Gender Remains a Significant Barrier to Access Cataract Surgery in South Asia: A Systematic Review and Meta-Analysis by Qunru Ye, Yanxian Chen, William Yan, Wei Wang, Jingxian Zhong, Cong Tang, Andreas Müller, Bo Qiu

“…Subgroup analyses by design and location types attained similar results as the primary analyses. …”
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Diagnosis and treatment of latent tuberculosis infection among household contacts in inland Bahia, Brazil: a cross-sectional follow-up study by Guilherme Lages Matias, Marcio Vinicius Ferreira Sales, Gabriela Santos Andrade, Brenda dos Santos Teixeira, Maria Eduarda da Macena Tenorio, Maria Augusta Vasconcelos Palácio, Maria Luisa de Carvalho Correia, Iukary Takenami

“…OBJECTIVE: To describe the diagnosis and treatment of LTBI among HHC. DESIGN AND SETTING: This cross-sectional follow-up study was conducted in the municipality of Paulo Afonso, northeastern Brazil, between 2013 and 2022. …”
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Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines by Wei-Yi Lei, Shih-Chieh Hsiung, Shao-Hsuan Wen, Chin-Hsuan Hsieh, Chien-Lin Chen, Christopher Glenn Wallace, Chien-Chung Chang, Shuen-Kuei Liao

“…These findings may have implications for a proper design of T cell immunotherapy for the treatment of sHCC patients.…”
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ST Elevation Myocardial Infarction in Patients with COVID-19: Case Series by Sofia Lakhdar, Chandan Buttar, Laura Guzman Perez, Nso Nso, Mahmoud Nassar, Giovina Collura

“…The authors used a retrospective case series design to evaluate the association between laboratory-confirmed COVID-19 infection and hospitalisation for acute myocardial infarction. …”
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Prevalence and sociodemographic characteristics of functional impairment in community-dwelling older adults in China: a cross-sectional study by Yun Li, Li Zhang, Zhe Tang, Lina Ma, Pan Liu, Xiaxia Li, Wenhua Yu, Yaxin Zhang

“…This study aimed to explore the prevalence and socio-demographic characteristics of functional impairment in Chinese community-dwelling older adults using the Function Impairment Screening Tool (FIST), which was previously developed based on the Delphi method.Design Cross-sectional study.Setting Community-based.Participants The study included 6444 community-dwelling older adults from the China Comprehensive Geriatric Assessment Study.Results The FIST identified functional impairment in 31.3% of Chinese community-dwelling older adults. …”
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Analysis of the practice of switch of antibiotics from intravenous to oral therapy at a tertiary care hospital in Nepal: a prospective observational study by Upasana Acharya, Sweta Shrestha, Aastha Rawal, Laxmi Dangol, Binaya Sapkota

“… Abstract Objective: This study analyzed the practice of switching intravenous antibiotics to oral dosage form in a tertiary care hospital of Nepal. Design: A prospective observational study was performed among patients admitted to medical/surgical wards in a private tertiary care hospital of Nepal. …”
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Comparative analysis of ChatGPT and Gemini (Bard) in medical inquiry: a scoping review by Fattah H. Fattah, Fattah H. Fattah, Abdulwahid M. Salih, Abdulwahid M. Salih, Ameer M. Salih, Ameer M. Salih, Saywan K. Asaad, Saywan K. Asaad, Abdullah K. Ghafour, Rawa Bapir, Rawa Bapir, Rawa Bapir, Berun A. Abdalla, Berun A. Abdalla, Snur Othman, Sasan M. Ahmed, Sasan M. Ahmed, Sabah Jalal Hasan, Yousif M. Mahmood, Fahmi H. Kakamad, Fahmi H. Kakamad, Fahmi H. Kakamad

“…Data collected from the studies included the first author's name, the country where the study was conducted, the type of study design, publication year, sample size, medical speciality, and the accuracy and response length.ResultsThe initial search identified 64 papers, with 11 meeting the inclusion criteria, involving 1,177 samples. …”
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A randomized double-blind clinical trial investigating the effects of ellagic acid on glycemic status, liver enzymes, and oxidative stress in patients with non-alcoholic fatty live... by Sara Mighani, Rasoul Samimi, Mohamadreza Rashidi Nooshabadi, Seyed Amir Farzam, Hossein Khadem Haghighian, Maryam Javadi

“…Considering the antioxidant features of Ellagic acid (EA), this study was designed to assess the effect of EA on some biochemical factors in patients with NAFLD. …”
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Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial by Yaadwinder Shergill, Danielle B. Rice, Eve-Ling Khoo, Virginia Jarvis, Tinghua Zhang, Monica Taljaard, Keith G. Wilson, Heather Romanow, Brittany Glynn, Rebecca Small, Joshua A. Rash, Andra Smith, Lynette Monteiro, Catherine Smyth, Patricia A. Poulin

“…A randomized controlled trial design was applied, and outcomes collected included pain, emotional function, quality of life, and global impression of change. …”
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The Role of the High-Sensitivity C-Reactive Protein in Patients with Stable Non-Cystic Fibrosis Bronchiectasis by Meng-Heng Hsieh, Yueh-Fu Fang, Guan-Yuan Chen, Fu-Tsai Chung, Yuan-Chang Liu, Cheng-Hsien Wu, Yu-Chen Chang, Horng-Chyuan Lin

“…The aim of this study is to investigate the correlation between serum high-sensitivity C-reactive protein (hs-CRP) and other clinical tools including high-resolution computed tomography (HRCT) in patients with stable non-CF bronchiectasis. Design. A within-subject correlational study of a group of patients with stable non-CF bronchiectasis, who were recruited from our outpatient clinic, was done over a two-year period. …”
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Local Binary and Multiclass SVMs Trained on a Quantum Annealer by Enrico Zardini, Amer Delilbasic, Enrico Blanzieri, Gabriele Cavallaro, Davide Pastorello

“…In practice, the fast local kernel support vector machine (FaLK-SVM) method, designed for efficient local SVMs, has been combined with quantum-trained SVM models for binary and multiclass classification. …”
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Differences and analogies in thyroid cancer discovered incidentally or by thyroid-related screening: a multicenter study by Laura Croce, Rosaria Maddalena Ruggeri, Camilla Virili, Carlo Cappelli, Marsida Teliti, Pietro Costa, Spyridon Chytiris, Antonio Nicocia, Francesca Coperchini, Maria Flavia Bagaglini, Flavia Magri, Alfredo Campennì, Mario Rotondi

“…Our aim was to assess the prevalence of thyroid-related disease (TD) versus incidental diagnosis (ID) pre-surgery reasons leading to TC diagnosis and to compare the two groups in terms of clinical characteristics, size and severity of TC at presentation and rate of non-thyroid cancers and cardiovascular/metabolic comorbidities. Design: We performed a retrospective cohort study in three high-volume hospital-based centers for thyroid diseases (Pavia, Latina and Messina) in Italy. …”
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Development trend of primary healthcare after health reform in China: a longitudinal observational study by Hui Li, Jie Feng, Zuxun Lu, Yanhong Gong, Xuan Zhou, Guopeng Zhang, Xiaoxv Yin, Jianxiong Wu

“…Nevertheless, there have been few studies focusing on the strengthening of primary healthcare in Chinese health system.Design This study was a longitudinal observational study.Primary and secondary outcome measures The data of this study came from China Health Statistical Yearbook (2009–2018). …”
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Estimating and forecasting bitcoin daily prices using ARIMA-GARCH models by Quang Phung Duy, Oanh Nguyen Thi, Phuong Hao Le Thi, Hai Duong Pham Hoang, Khanh Linh Luong, Kim Ngan Nguyen Thi

“…The study looks at how predictable Bitcoin price swings and market volatility will be between 2021 and 2023. Design/methodology/approach – The data used in this study are the daily closing prices of Bitcoin from Jan 17th, 2021 to Dec 17th, 2023, which corresponds to a total of 1065 observations. …”
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SumGPT: A Multimodal Framework for Radiology Report Summarization to Improve Clinical Performance by Tipu Sultan, Mohammad Abu Tareq Rony, Mohammad Shariful Islam, Samah Alshathri, Walid El-Shafai

“…The SumGPT technique was evaluated against several baseline models, including BERT + EfficientNet, XLM-RoBERTa + ViT, T5+ CLIP, VisualGPT (GPT-2+ ViT), and others, using a dataset explicitly designed for this task. The experimental results indicate that SumGPT outperformed all baseline models, achieving the highest performance across all metrics. …”
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Enhancing the targeted and untargeted analysis of honey by vacuum-assisted SPME-GC × GC-MS. A green, practical, and highly informative approach by Damien Eggermont, Francesca Pardi, Giorgia Purcaro

“…The use of Vac-HS-SPME has been optimized using an experimental design and compared to the atmospheric pressure extraction. …”
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Sustained immunogenicity of bivalent protein COVID-19 vaccine SCTV01C against antigen matched and mismatched variants by Guiqiang Wang, Kexin Zhao, Xiuli Zhao, Yimin Cui, Peng He, Tianzuo Zhang, Yanchao Wang, Rui Shi, Yanhua Li, Qian Wang, Yanping Ren, Zhisong Chen, Xuedan Zhao, Zekang Xie, Yufei Liang, Qingyun Tian, Jing Pan, Chao Zhang, Ying Han, Yuyang Dai, Siyang Ni, Yun Zhang, Xinjie Yang, Yongpan Fu, Dongfang Liu, Jing Li, Miaomiao Zhang, Zhongyu Hu, Liangzhi Xie

“…Background The development of bivalent or multivalent vaccines offers a promising strategy for combating SARS-CoV-2 mutations.Research design and methods In this phase 2 trial, conducted from 1 December 2021, to 25 July 2023, 392 unvaccinated adults aged ≥18 years were randomized to receive a primary series of two doses and a booster dose of SCTV01C, a bivalent protein SARS-CoV-2 vaccine.Results Geometric mean titers (GMTs) of neutralizing antibodies (nAb) against live Alpha, Beta, Delta, and Omicron showed 85.4-, 100.0-, 32.1-, and 9.8-fold increase from baseline on 28 days, and 49.4-, 55.3-, 5.7-fold increase against live Alpha, Beta, and Omicron on 90 days after primary series. …”
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