EV‐Elute: A universal platform for the enrichment of functional surface marker‐defined extracellular vesicle subpopulations by Willemijn S. deVoogt, Rowan Frunt, Raul M. Leandro, Casper S. Triesscheijn, Bella Monica, Ioanna Paspali, Mark Tielemans, Jerney J. J. M. François, Cor W. Seinen, Olivier G. deJong, Sander A. A. Kooijmans

“…Here, we used the Design‐of‐Experiments (DoE) methodology to optimize a protocol, which we name ‘EV‐Elute’, to elute intact EVs from commercially available Protein G‐coated magnetic beads. …”
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Combining Unity with machine vision to create low latency, flexible and simple virtual realities by Yuri Ogawa, Raymond Aoukar, Richard Leibbrandt, Jake S. Manger, Zahra M. Bagheri, Luke Turnbull, Chris Johnston, Pavan K. Kaushik, Jaxon Mitchell, Jan M. Hemmi, Karin Nordström

“…This can be implemented programmatically in Unity, or by using our new tool CAVE, which allows users to design new experiments without additional programming. We provide resources for replicating experiments and our interface CAVE via GitHub, together with user manuals and instruction videos, for sharing with the wider scientific community.…”
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Characterization of the Collagen Extraction Manufacturing Process Using Markov Chains and Artificial Neural Networks by Rosa Trasvina-Osorio, Sergio Alonso-Romero, Juan de Anda-Suarez, Valentin Calzada-Ledesma, Javier Yanez-Mendiola, Luis Fernando Villanueva-Jimenez, Erick Rojas-Mancera

“…Empirical data from a design of experiments (DoE) fed a Markov chain Monte Carlo algorithm in an artificial neural network (MCMC-ANN) for data imputation, numerical simulation, and training. …”
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Time-dependent robust reliability optimization of structure based on genetic interval affine response surface by GUAN Yi, SHENG GuoJun

“…Secondly, the parametric analysis model of the structure was established, and design of experiment was carried out. The process of design of experiment was divided into two parts which were design variable database and structural performance response database. …”
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Shifting the Value of Experience by Michael T Lai, Hsien-Hui Tang

“…The authors compare and contrast the nature of experience design and experience strategy and how they are delivered to close the gap between designers and strategists. …”
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Self-defence model of SIP proxy server for against DoS attack by ZHANG Zhao-xin, DU Yue-jin, LI Bin, ZHANG Hong-li

“…Through deeply analyzing on the principle,mode,character of DoS,and the DoS attack faced by SIP network,combining with the idea of Client Puzzle,DFA,long-distance linkage,host linkagethe,the character of SIP network,and the principle of SIP proxy server,the defence model of SIP proxy server for DoS attack was put forward,and the testbed to test the ability of this model to resist DoS attack was designed.The experiment result proves that this model can effectively resist the DoS attack for SIP proxy server with millisecond delay of signal transfer,and improves the usablity of SIP network.…”
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SIMULATION OF FLUID FLOW THROUGH A STAINLESS STEEL GLOBE VALVE USING ENGINEERING FLUID DYNAMICS by Nguyen Huu Tho

“…This paper presents the design and simulation of fluid flow through the globe valve using CAD/CAE tools such as Autodesk CFD. Besides, design of experiment technique Box-Behnken is used to integrate the CFD simulation to identify the optimal design parameters of the globe valve. …”
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Third-Party Punishment Mechanism and Corporate Cooperation in Environmental Investment: Experiments on Public Goods Game by Yuling Liao, Liang Zhang, Siying Lei, Meizhe Song, Wenkang Deng, Daofu Hu

“…In the context of corporate environmental investment (EI), this paper designs an experiment on public goods game without punishment and an experiment on that game with third-party punishment (TPP). …”
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Design, Experiment, and Commissioning of the Spent Fuel Conveying and Loading System of HTR-PM by Bin Wu, Jinhua Wang, Yue Li, Haitao Wang, Tao Ma

“…Functional tests were carried out to indicate the items of mechanical and electrical equipment are functioning in accordance with the designed requirements. Experience learned from commissioning activities was also presented as feedback for future operation and design improvement.…”
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Research on HTML5 application cache poison attack by Yan JIA, He WANG, Shao-qing LYU, Yu-qing ZHANG

“…HTML5 application cache (AppCache) allowed Web browser to access Web offline.But it also brought a new method of cache poisoning attack that was more persisting.As for websites which used the AppCache,a novel poisoning method RFTM (replace file twice method),in which the attacker replaced the manifest file twice to poison the client’s AppCache,was proposed.Compared with the original attack,the legal server would not receive abnormal HTTP requests from the client in the attack.Therefore,changing the server configuration could not prevent the client from the RFTM AppCache poisoning.To avoid the attack mentioned above,a lightweight signature defense scheme Sec-Cache in application layer was designed.Furthermore,experiments show that it has good performance and compatibility.…”
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OPTIMUM PRODUCTION AND CHARACTERIZATION OF BIODIESEL FROM MICROCYSTIS AERUGINOSA ALGAE by BABATOPE OLUFEMI, SALEEM SULAIMON, ADEWALE ARIKAWE

“…Optimization with Minitab software was used to design the experiment using Central Composite Design (CCD). …”
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Load Tooth Contact Analysis for Arc Tooth Face Gear Considering Assembly Misalignment by Cui Yanmei, Fang Zongde, Wang Xing

“…The method for the tooth face gear pair provides systematic theoretical direction such as the design,the experiment and the application.…”
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Digital twin enhanced agile design of ship pipeline systems [version 2; peer review: 1 approved, 3 approved with reservations] by Xin Wang, Kang Cui, Xiaofen Shan, Zhinan Zhang

“…It predominantly relies on designers’ subjective experience, and it is marked by a lack of efficient knowledge sharing and the absence of smart pipe routing algorithms. …”
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Configuration Reconfigurable Design and Experimental Study of Controllable 5R Planar Parallel Mechanism by Hou Zhili, Wu Wenge, Li Ruiqin, Qin Huibin, Zhao Jianwen

“…The contrastive analysis of the output trajectory tracking before and after the drive layout configuration transformation is carried out,the result shows that the workspace is expanded. Through designing the experiment device,the effectiveness of solving the workspace by trajectory tracking method is verified.…”
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STUDY OF THE PROPERTIES OF PROTIC IONIC LIQUIDS TO BE APPLIED IN THE ENHANCED OIL RECOVERY by G. F. D. Ferreira, C. B. M. Lima, S. Mateddi, L. C. L. Santos, A. K. C. L. Lobato

“…The aim of this paper is to study the ionic liquid [2HEA] [Hx] in order to evaluate the influence of its concentration and the salinity on the interfacial tension between oil and a solution of ionic liquid, through the statistical designing of experiments. It was verified that the IL [2HEA] [Hx] was able to decrease the interfacial tension between oil and the water solution and that both the ionic and salt concentrations were significant for the reduction of interfacial tension.…”
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STRUCTURE OPTIMIZATION DESIGN FOR THE ROTARY WORKTABLE OF GANTRY MACHINING CENTER BASED ON RESPONSE SURFACE METHODOLOGY by ZHENG Bin, ZHANG JingDong

“…In order to increase the stiffness and reduce the weight of rotary worktable,the main design parameters are tested by Box-Behnken experiment design.Based on the design of experiment,sensitivity analysis is carried out for design parameters and the response surface model is established. …”
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Laser Doppler Vibrometer: Application of DOE/Taguchi Methodologies to Pyroshock Response Spectra by C. J. Litz

“…The application of design of experiment methodology was made to structure and test a Taguchi L9(32) full factorial experimental matrix (which uses nine tests to study two factors, with each factor examined at three levels) in which a helium-neon laser Doppler vibrometer and two piezocrystal accelerometers were used to monitor explosively induced vibrations ranging from 10 to 105 Hz on a 96 × 48 × 0.25 in. flat steel plate. …”
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Simple Ion Transfer at Liquid|Liquid Interfaces by L. J. Sanchez Vallejo, J. M. Ovejero, R. A. Fernández, S. A. Dassie

“…These numerical simulations are correlated with selected experimental results; their usefulness in designing new experiments is summarized. Finally, many practical applications can be envisaged regarding the determination of physicochemical properties, electroanalysis, drug lipophilicity, and phase-transfer catalysis.…”
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Analisa Produk Pola Cetakan Lilin yang Diproduksi Menggunakan DIY-CNC-Endmill by Firman Ridwan, Ryan Rahman

“…For this reason, therefor, an End-Milling type CNC machines that has accuracy of up to 1/1000 mm is designed. The experiments showed that the results with high accuracy having standard deviation of repeatability of inner diameter 0.020736441, repeatability of outer diameter 0.020493902 and repeatability of thickness 0.043817805.…”
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Design and digital transition. New design-driven challenges for techno-social innovation by Salvatore Di Dio, Benedetto Inzerillo, Francesco Monterosso, Dario Russo

“…Starting from theoretical reflections and multidisciplinary contributions, this paper focuses on the strategic importance of techno-social innovation, critically illustrating some significant design-driven experiences that outline innovative lines of development in the field of design research: WASP’s experimental activity (3D printing), Manzini’s reflections on hybrid local communities and cities in chaotic mutation, the projects of hacktivists Persico and Iaconesi on open source artificial intelligence, the experiences of frugal technological innovation with high social impact in the Planet’s most challenging economic, environmental and social contexts, and, finally, the bold projections on the food of the future with the related problematic experiments on production systems and lifestyles. …”
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