Development and Evaluation of Nanoemulsifying Preconcentrate of Curcumin for Colon Delivery by Jyoti Wadhwa, Abhay Asthana, Gyati Shilakari, Arun Kumar Chopra, Ranjit Singh

“…Content of formulation variables, namely, X1 (Peceol), X2 (Cremophor-EL), and X3 (Transcutol HP), were optimized by Box-Behnken design of experiments for its impact on mean globule size (Y1), emulsification time (Y2), and time required for drug release (85%) in phosphate buffer (pH 7.2), t85% (Y3). …”
Get full text

Optimal conditions for the biological removal of ammonia from wastewater of a petrochemical plant using the response surface methodology by M. Samimi, M. Shahriari Moghadam

“…Effect of the main operational variables such as ammonia concentration, residence time and Lemna gibba to surface ratio on optimal conditions of ammonia removal from wastewater has been analyzed using  the Box-Behnken model design of experiments. Model numerical optimization was performed to achieve the maximum amount of ammonia removal from wastewater. …”
Get full text

Aspergillus terreus variant TB21 wet biomass optimized by in-situ transesterification for biodiesel production by Rashmi K. Bed, V. Ravi Kumar, Ameeta RaviKumar

“…The fungal wet biomass grown on sugarcane bagasse hydrolysate (SCBH) was subjected to one-step in-situ (direct) acid transesterification to optimize its conversion to biodiesel using a 2-level factorial statistical design of experiments. The process optimization revealed that wet biomass and methanol were the most significant factors and in a short reaction time period of 5 min with low methanol: wet biomass ratio (10:1) influenced FAME production Statistical optimization studies showed that TB21 exhibited a higher FAME content of 76.5 and 38.1% (w/w) from wet and dry biomass, respectively when compared to wild type (48.1 and 24.5%). …”
Get full text

A new generation of ecocatalysts$^{\text{®}}$—from Invasive Alien Species to sustainable and biosourced glyceryl fatty esters by Lasbleiz, Arthur, Pelissier, Franck, Renault, Jean-Hugues, Grison, Claire M., Legrand, Yves-Marie, Grison, Claude

“…After calculating Pearson’s correlations to evaluate the relative importance of reaction parameters, a design of experiments (DoE) was implemented to synthesize glyceryl caprylate and oleate with a high selectivity. …”
Get full text

Electromagnetic design, sensitivity analysis, optimization and Multiphysics capability of rare-earth-free synchronous reluctance motor for electric trike vehicle by V Rajini, VS Nagarajan, Karunya Harikrishnan, Mohan Lal Kolhe

“…This paper also focuses on an optimal design of the FASRM due to its high torque density, lower torque ripple, and minimal use of ferrite magnets. A Design of Experiments (DoE)-based statistical analysis tool is used to identify the key parameters needed for robust motor performance in the optimization step. …”
Get full text

Performance evaluation of bio/chemical leaching solution and nano catalyst in upgrading and enhancing oil recovery by Mohammad Hossein Shabani, Parya Torkaman, Hamidreza Farshadfar, Arezou Jafari, Seyyed Mohammad Mousavi

“…We investigated the effects of various parameters influencing this process, including catalyst type, concentration, and reaction temperature, using design of experiments methodologies. The recovery of metal from electric arc furnace dust during chemical leaching was 15.1 %, while it was only 3.2 % in biological leaching. …”
Get full text

Reactive dye extraction utilizing regenerated bleaching earth by M. Shahi, M.R. Sabour, G.A. Dezvareh

“…Response surface methodology was used to design the experiments and determine the optimal parameters in order to run the dye adsorption process. …”
Get full text

Effect of Dynamic Corrosion and Degradation on Fatigue Life of an AA2024-T3 Aircraft Profile: Experimental, Statistical, and Numerical Analyses by Gilberto Daniel Conejo Magaña, Víctor García García, Daniel Cahue Díaz, Nicolás Herrera-Sandoval, Orlando Hernández Cristóbal

“…An orthogonal L9 design of experiments (Taguchi method) was applied to promote high pitting corrosion through the quality characteristic “the higher the better”. …”
Get full text

Thermo-elastic topology optimization and experimental characterization for multiphase structure with high thermal stiffness invariability by Yiming Fan, Guangkai Wei, Yuan Chen

“…These results for designing 3D multiphase structures demonstrate that using the HTSI design can reduce thermally induced stiffness fluctuation by 24.4% when compared to the GTE design by experiments. The numerical accuracy was also validated with an error of only 7.7%.…”
Get full text

Statistical Model for the Mechanical Properties of Al-Cu-Mg-Ag Alloys at High Temperatures by A. M. Al-Obaisi, E. A. El-Danaf, A. E. Ragab, M. S. Soliman, A. N. Alhazaa

“…Statistical models, based on fractional factorial design of experiments, were constructed to relate the experiments output (yield strength and ultimate tensile strength) with the studied process parameters, namely, tensile testing temperature, aging time, and copper, magnesium, and silver contents. …”
Get full text

Multi-scale mechanical properties of Al–Mg–Zr–Sc alloys fabricated by direct metal laser sintering: Towards single-material composites by Dominic Zettel, Piotr Breitkopf, Ludovic Cauvin, Pascal Nicolay, Roland Willmann

“…Eighty-five specimens were produced using seventeen distinct parameter sets, designed through a Design of Experiments approach, and subjected to non-destructive and destructive testing. …”
Get full text

Experimental Approach for the Evaluation of the Performance of a Satellite Module in the CanSat Form Factor for In Situ Monitoring and Remote Sensing Applications by Juan Sebastián Rodríguez, Andrés Yarce Botero, Diego Valle, Julián Gálvez- Serna, Francisco Botero

“…To evaluate its performance and ensure the precision and accuracy of the measurements made by the satellite prototype, a methodology was designed and implemented for the characterization and qualification of CanSats (soda can satellites) through statistical tests and techniques of DoE (Design of Experiments) based on CubeSat aerospace standards and regulations, in the absence of official test procedures for these kinds of satellite form factor. …”
Get full text

Amplifying the Sensitivity of Electrospun Polyvinylidene Fluoride Piezoelectric Sensors Through Electrical Polarization Process for Low-Frequency Applications by Asra Tariq, Amir H. Behravesh, Muhammad Tariq, Ghaus Rizvi

“…In this study, a Design of Experiments (DoE) approach was employed to systematically optimize the polarization parameters using a definitive screening design. …”
Get full text

Machine learning assisted prediction with data driven robust optimization: Machining process modeling of hard part turning of DC53 for tooling applications supporting semiconductor... by Mehdi Tlija, Muhammad Sana, Anamta Khan, Sana Hassan, Muhammad Umar Farooq

“…A full factorial design of experiments with two levels, resulting in 16 experiments, is performed with statistical parametric significance analysis to better control process variability. …”
Get full text

Optimization of Ionic Liquid Based Simultaneous Ultrasonic- and Microwave-Assisted Extraction of Rutin and Quercetin from Leaves of Velvetleaf (Abutilon theophrasti) by Response Su... by Chunjian Zhao, Zhicheng Lu, Chunying Li, Xin He, Zhao Li, Kunming Shi, Lei Yang, Yujie Fu, Yuangang Zu

“…The influential parameters of the ILs-UMAE were optimized by the single factor and the central composite design (CCD) experiments. A 2.00 M 1-butyl-3-methylimidazolium bromide ([C4mim]Br) was used as the experimental ionic liquid, extraction temperature 60°C, extraction time 12 min, liquid-solid ratio 32 mL/g, microwave power of 534 W, and a fixed ultrasonic power of 50 W. …”
Get full text

A successful case study of using HCl and viscoelastic diverting acid systems for carbonate matrix acidizing in an oil well with optimized predictive model by Javad Mahdavi Kalatehno, Ehsan Khamehchi, Mostafa Keihanikamal, Fatemeh Yousefmarzi, Matin Dargi, Peyman Daneshfar

“…The study integrates design of experiments (DOE) and multi-objective optimization techniques to assess the impact of various operational parameters on acidizing performance. …”
Get full text

Optimising Palm Olein-Based Betamethasone 17-Valerate Emulsions for Scalable Manufacturing and Stability by Thazin Win, Mohd. Rushdi Abu Bakar, Farahidah Mohamed, Muhammad Taher, Md. Zaidul I. Sarker

“…Methods: This research work established and optimised the manufacturing process parameters for the production of cream and lotion formulations containing betamethasone 17-valerate, utilising palm olein as the vehicle, with scale-up from lab-scale 5 kg batches to pilot-scale 80 kg batches. Design of experiments (DoE) where response surface methodology as well as three-level, two-factors (32) full factorial design were used to develop statistical models for representing the possible relationships between factors: homogenisation time and speed, and responses: particle size and phase separation. …”
Get full text

Critical quality indicators of high-performance polyetherimide (ULTEM) over the MEX 3D printing key generic control parameters: Prospects for personalized equipment in the defense... by Nectarios Vidakis, Markos Petousis, Constantine David, Nektarios K. Nasikas, Dimitrios Sagris, Nikolaos Mountakis, Mariza Spiridaki, Amalia Moutsopoulou, Emmanuel Stratakis

“…The examination was performed with optical profilometry, optical microscopy, and micro-computed tomography scanning. The Taguchi design of experiments was applied, with twenty-five runs, five levels for each control parameter, on five replicas. …”
Get full text

Optimal Suppression of Photocatalytic Activity of Hybrid TiO2 Particles in Epoxy Thin Film by Using Taguchi Method by Sunderishwary S. Muniandy, Tan Sek Soon, Swee Yong Pung, Sivakumar Ramakrishnan

“…The Taguchi L9 orthogonal array, a systematic approach used in the design of experiments (DOE), confirmed A333 (Al2O3-TiO2) achieved 99% photodegradation suppression with photodegradation rate reduced significantly from 0.01305 min−1 to 0.00009 min−1 and improved yellowing resistance by 63%, while S323 (SiO2-TiO2) achieved 75% suppression with photocatalysis activity decreased from 0.01305 min−1 to 0.0033 min−1 and 42% improved resistance. …”
Get full text

Development of an analytical method for the simultaneous determination of 22 Polycyclic Aromatic Hydrocarbons (PAHs) in maternal and umbilical cord blood by Swiha, Stéphanie, Pichon, Valérie, Fournier, Thierry, Gil, Sophie, Delaunay, Nathalie

“…Then, to break any interactions between PAHs and serum proteins, a precipitation step prior to solid-phase extraction was optimized using a design of experiments. The final sample processing procedure led to extraction yields of between 27 and 57% and between 34 and 69% for 22 PAHs in serum and umbilical cord blood, respectively, with standard deviation values of less than 11%. …”
Get full text