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101
Urinary Macrophage Migration Inhibitory Factor Serves as a Potential Biomarker for Acute Kidney Injury in Patients with Acute Pyelonephritis
Published 2012-01-01“…Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine, and the predictive role and pathogenic mechanism of MIF deregulation during kidney infections involving acute kidney injury (AKI) are not currently known. …”
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102
RNase Y mediates posttranscriptional control of the virulence-associated CncR1 small-RNA in Helicobacter pylori
Published 2025-02-01“…The observation that the RNAse Y-mutant strain showed deregulation of several members of the CncR1 regulon suggests this ribonuclease has an important role in H. pylori posttranscriptional regulation.…”
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103
Mathematical insights on psoriasis regulation: Role of Th1 and Th2 cells
Published 2018-05-01“…Interferon gamma ( $\mbox{IFN}-{γ}$ ), Transforming growth factor beta ( $\mbox{TGF}-β$ ) and Tumor necrosis factor alpha ( $\mbox{TNF}-α$ ) etc. Deregulation of epidermal happens due to signaling of anti-inflammatory cytokines like Interleukin 10 ( $\mbox{IL}-{10}$ ), Interleukin 4 ( $\mbox{IL}-{4}$ ) etc., released by Th2-Cells. …”
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104
Christophe Charle, le parcours et les idées d'un historien
Published 2015-04-01“…Il publie en 2015 La dérégulation culturelle, essai d’histoire des cultures en Europe. …”
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105
Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer
Published 2018-01-01“…In this context, different hematological and solid tumors are characterized by deregulation of the protein acetylation pattern as a result of genetic or epigenetic changes. …”
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106
Calcium and s100a1 Protein Balance in the brain– Heart axis in Diabetic Male Wistar Rats.
Published 2023“…Objectives: Calcium deregulation in diabetes mellitus (DM) is central to the brain–heart axis pathology. …”
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107
Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta
Published 2025-02-01“…Finally, we observed a significant deregulation of 3 main types of non-coding RNAs (ncRNAs): long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and small nucleolar RNAs (snoRNAs), some of which are common to coronaviruses, and some specific to SARS-CoV-2. …”
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108
Altered Phenotype of Circulating Dendritic Cells and Regulatory T Cells from Patients with Acute Myocarditis
Published 2022-01-01“…This proinflammatory status may contribute to the pathogenesis and immune deregulation in acute myocarditis.…”
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109
Alterations in Mesenteric Lymph Node T Cell Phenotype and Cytokine Secretion are Associated with Changes in Thymocyte Phenotype after LP-BM5 Retrovirus Infection
Published 2005-01-01“…Simultaneous analysis of surface markers and cytokine secretion was done in an attempt to understand whether the deregulation of IFN-Υ secretion could be ascribed to a defined cell phenotype, concluding that all T cell subsets studied increased IFN-Υ secretion after retrovirus infection. …”
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110
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway
Published 2025-02-01“…Abstract Bladder cancer (BLCA) is one of the ten most common cancers worldwide. However, the deregulation of PROS1 and its specific function in BLCA is not well understood. …”
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111
Spatiotemporal Variability in Wind Turbine Blade Leading Edge Erosion
Published 2025-01-01“…Thus, it may be more cost-effective to use wind turbine deregulation (erosion-safe mode) for damage reduction and blade lifetime extension in the SGP, while the application of blade leading edge protective measures may be more appropriate in the PNW. …”
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112
Measuring the implementation of the rule of law in society and the state
Published 2021-12-01“…It is established that in view of the new challenges caused by globalization and trends of deregulation, the implementation of the rule of law should be expanded. …”
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113
β Common Receptor Mediates Erythropoietin-Conferred Protection on OxLDL-Induced Lipid Accumulation and Inflammation in Macrophages
Published 2015-01-01“…In the current study, we investigated the role of βCR in EPO-mediated protection in macrophages against oxidized low-density lipoprotein- (oxLDL-) induced deregulation of lipid metabolism and inflammation. Here, we show that βCR expression was mainly in foamy macrophages of atherosclerotic aortas from apolipoprotein E-deficient mice. …”
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114
Loss of YTHDC1 m6A reading function promotes invasiveness in urothelial carcinoma of the bladder
Published 2025-01-01“…Our findings establish YTHDC1-dependent m6A reading as a critical epitranscriptomic mechanism regulating bladder cancer invasiveness and provide a paradigm for the epitranscriptomic deregulation of cancer-associated networks.…”
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115
Managing online crisis-communication response in a South African bank
Published 2022-10-01“… Deregulation and rapid growth in technology removed entry barriers in the online environment, thereby forcing financial institutions to transform and at the same time to conquer consumer’s fear and the perceived risk of fraudulent online transactions. …”
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116
Study of miRNA Based Gene Regulation, Involved in Solid Cancer, by the Assistance of Argonaute Protein
Published 2016-09-01“…In the current work, 64 genes and 23 miRNAs have been selected from literatures, whose deregulation is well established in seven types of solid cancer like lung, breast, prostate, pancreases, colorectal, stomach, and bladder cancer. …”
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117
MAP4 kinase-regulated reduced CLSTN1 expression in medulloblastoma is associated with increased invasiveness
Published 2025-01-01“…MB is associated with impaired differentiation of specific neural progenitors, suggesting that the deregulation of proteins involved in neural physiology could contribute to the transformed phenotype in MB. …”
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118
Loss of correlated proteasomal subunit expression selectively promotes the 20SHigh state which underlies luminal breast tumorigenicity
Published 2025-01-01“…By integrating the gene coexpression signatures of proteasomal subunits in breast cancer (BrCa) patient tissues with the atomistic details of 26S holocomplex, we find that the transcriptional deregulation induced-stoichiometric imbalances perpetuate with disease severity. …”
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119
The ACE2/Apelin Signaling, MicroRNAs, and Hypertension
Published 2015-01-01“…The physiological effects of Apelin are exerted through binding to its receptor APJ, a seven-transmembrane G protein-coupled receptor that shares significant homology with the Ang II type 1 receptor (AT1R). The deregulation of microRNAs, a class of short and small noncoding RNAs, has been shown to involve cardiovascular remodeling and pathogenesis of hypertension via the activation of the Ang II/AT1R pathway. …”
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120
Régimes de duplicité, espaces désesthétisés
Published 2010-01-01“…Un travail de terrain, effectué dans des centres de réfugiés tchétchènes en Pologne, met en évidence les différents niveaux de ce régime de duplicité, inscrivant le biopolitique non pas seulement dans la perspective classiquement foucaldienne d’un régime de contrôle, mais dans les contradictions internes d’un contrôle accru et d’une dérégulation. Sans cesse, les migrants sont confrontés à cette duplicité juridique et politique qui fait de la « régulation des flux » une pure et simple amorce de la disparition des personnes. …”
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