Classification of schizophrenia, bipolar disorder and major depressive disorder with comorbid traits and deep learning algorithms by Xiangning Chen, Yimei Lu, Joan Manuel Cue, Mira V. Han, Vishwajit L. Nimgaonkar, Daniel R. Weinberger, Shizhong Han, Zhongming Zhao, Jingchun Chen

“…In this study, we use polygenic risk scores (PRSs) of 42 traits comorbid with schizophrenia (SCZ), bipolar disorder (BIP), and major depressive disorder (MDD) to evaluate their utilities. We found that combining target specific PRS with PRSs of comorbid traits can improve the classification of the target disorders. …”
Get full text

Interpersonal Psychotherapy for Bereavement-Related Major Depressive Disorder in Japan: A Systematic Case Report by Yuko Toshishige, Masaki Kondo, Junya Okazaki, Hiroko Mizushima, Tatsuo Akechi

“…Bereavement-related major depressive disorder (MDD) is a common disorder with both mental and physical effects. …”
Get full text

Association between abnormal default mode network homogeneity and sleep disturbances in major depressive disorder by Ping Li, Feng Liu, Jingping Zhao, Muzhi Huang, Yangpan Ou, Huabing Li, Bing Lang, Wenbin Guo

“…Background Sleep disturbance is a common comorbidity of major depressive disorder (MDD). However, network homogeneity (NH) changes of the default mode network (DMN) in MDD with sleep disturbances are unclear.Aims The purpose of this study was to probe the abnormal NH in the DMN in MDD with sleep disturbances and to reveal the differences between MDD with or without sleep disturbances.Methods Twenty-four patients with MDD and sleep disturbances (Pa_s), 33 patients with MDD without sleep disturbances (Pa_ns) and 32 healthy controls (HCs) were recruited in this study. …”
Get full text

Electroencephalographic markers in Major Depressive Disorder: insights from absolute, relative power, and asymmetry analyses by Mehmet Akif Özçoban, Oğuz Tan

Subjects: “…Major Depressive Disorders…”
Get full text

Association between sleep disorder and anhedonia in adolescence with major depressive disorder: the mediating effect of stress by Xinxin Zhao, Hongzhe Ma, Ning Li, Wenjun Wu, Xinxu Ma, Xinxin Zhang, Wenming Liu, Lei Shang, Huaning Wang, Hailong Dong, Chen Li, Guangchao Zhao, Min Cai

Subjects: “…Major depression disorder…”
Get full text

Algorithm-informed treatment from EEG patterns improves outcomes for patients with major depressive disorder by Ramon Solhkhah, Justin Feintuch, Mabel Vasquez, Eamon S. Thomasson, Vijay Halari, Kathleen Palmer, Morgan R. Peltier

“…Objective: Selecting the right medication for major depressive disorder (MDD) is challenging, and patients are often on several medications before an effective one is found. …”
Get full text

A Case Series: Adjunctive Treatment of Major Depressive Disorder in the Geriatric Population with the Methylphenidate Patch by Kamal Patel, Ashley Collins, Suzanne Holroyd, Andre Benja Lamyaithong

“…Major depressive disorder can affect anyone regardless of age. …”
Get full text

The immunological perspective of major depressive disorder: unveiling the interactions between central and peripheral immune mechanisms by Wenli Jiao, Jiayi Lin, Yanfang Deng, Yelin Ji, Chuoyi Liang, Sijia Wei, Xi Jing, Fengxia Yan

Subjects: “…Major depressive disorder…”
Get full text

Immediate and sustained efficacy of Deep Brain Stimulation for major depressive disorder with persistent suicidal ideation by Botao Xiong, Changjian Qiu, Wei Zhang, Wei Wang

Subjects: Get full text

MicroRNA-451a is a candidate biomarker and therapeutic target for major depressive disorder by Yan Chen, Yun Liu, Ming Xiao, Chun Wang, Panpan Hu, Qiuchen Cao, Hu Feng, Jingfan Xu, Weixi Feng, Huaiqing Sun, Huachen Ding, Junying Gao

“…Background Increasing evidence supports the role of microRNAs (miRNAs) in major depressive disorder (MDD), but the pathophysiological mechanism remains elusive.Aims To explore the mechanism of microRNA-451a (miR-451a) in the pathology and behaviours of depression.Methods Abnormal miRNAs such as miR-451a reported previously in the serum of patients with MDD were screened and then confirmed in a mouse model of depression induced by chronic restraint stress (CRS). …”
Get full text

Study of Gaming Disorder and Its Association with Depressive Disorder and Anxiety among Medical Students in India by Hanee Patel, Niraj Pandit, Rudra Patel, Ishita Gupta, Dhairya Jain, Shreya Katoch

Subjects: Get full text

The Interaction Effects of Suicidal Ideation and Childhood Abuse on Brain Structure and Function in Major Depressive Disorder Patients by Wei Wang, Lijun Kang, Nan Zhang, Xin Guo, Peilin Wang, Xiaofen Zong, Lihua Yao, Hanping Bai, Jing Cheng, Ning Tu, Hongyan Feng, Gaohua Wang, Lihong Bu, Fei Wang, Zhongchun Liu

“…To explore the interaction effect between SI and childhood abuse, 215 patients with major depressive disorder completed the Childhood Trauma Questionnaire to evaluate childhood abuse and Beck’s Scale for Suicidal Ideation to evaluate SI. …”
Get full text

Prevalence of depressive disorders among pregnant women in Brazil in 2019: A descriptive cross-sectional study by Maira Gonçalves de Oliveira Lucas, Maria Isabel do Nascimento

Subjects: “…Depressive disorder.…”
Get full text

A Revision on the Effectiveness of Omega-3 Polyunsaturated Fatty Acids as Monotherapy in the Treatment of Major Depressive Disorder by Tommaso Accinni, Matteo Panfili, Lorenzo Tarsitani, Massimo Biondi, Massimo Pasquini, Annalisa Maraone

“…Insufficient effectiveness and a difficult tolerability profile of antidepressant drugs for the treatment of major depressive disorder (MDD) have been reported, and polyunsaturated fatty acids (PUFAs) have been posited as reliable therapeutic alternatives. …”
Get full text

Differentiation value of miR-26b for major depressive disorder, schizophrenia, generalized anxiety disorder by Lingming Kong, Xiaoli Zhu, Liyi Zhang, Shengdong Chen

“…Introduction: First episode and drug naive schizophrenia (SZ) patients comorbid with major depressive episode and generalized anxiety disorder (GAD) comorbid with major depressive disorder (MDD) are common in clinical practice, overlapping symptomatology during first presentation of MDD, SZ and GAD challenged the diagnostic process. …”
Get full text

Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context by Thuy-Dung Nguyen, Joeri J. Meijsen, Robert Sigström, Ralf Kuja-Halkola, Ying Xiong, Arvid Harder, Kaarina Kowalec, Joëlle A. Pasman, Carolina Scarpa, Elin Hörbeck, Lina Jonsson, Sara Hägg, Niamh Mullins, Kevin S. O’Connell, Christina Dalman, Dorte Helenius, Richard Zetterberg, Henrik Larsson, Paul Lichtenstein, Ole A. Andreassen, Thomas Werge, Alfonso Buil, Mikael Landén, Patrick F. Sullivan, Yi Lu

Subjects: “…Psychotic major depressive disorder…”
Get full text

Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Transcranial Infrared Laser Stimulation by Douglas W. Barrett, Christopher G. Beevers, F. Gonzalez-Lima

Subjects: Get full text

Relationship of Asymmetrical Dimethylarginine, Nitric Oxide, and Sustained Attention during Attack in Patients with Major Depressive Disorder by Serpil Canpolat, İsmet Kırpınar, Erdem Deveci, Hülya Aksoy, Zafer Bayraktutan, İbrahim Eren, Recep Demir, Salih Selek, Nazan Aydın

“…We investigated the relationship of serum nitric oxide (NO) and asymmetrical dimethylarginine (ADMA) levels with cognitive functioning in patients with major depressive disorder (MDD). 41 MDD patients (Beck depression scale scores >16) and 44 controls were included in the study. …”
Get full text

Brain function abnormalities and inflammation in HIV-positive men who have sex with men with depressive disorders by Yang Zhang, Yang Zhang, Yihui He, Yihui He, Yuan Fang, Yuan Fang, Miaotian Cai, Guangqiang Sun, Guangqiang Sun, Rui Wang, Rui Wang, Jiaxin Zhen, Jiaxin Zhen, Yulin Zhang, Zhen Li, Zhen Li, Yundong Ma, Yundong Ma, Tong Zhang, Tong Zhang

Subjects: Get full text

Sex-Based Variations in Hemato-Physiological Characteristics of Patients with Major Depressive Disorder: Clinical and Socioeconomic Insights by Basim A. Abd, Hayder Abdul-Amir Makki Al-Hindy, Samer Raheem Obaid

“…Background: Major depressive disorder (MDD) is a well-known psychiatric condition that can affect a diverse range of populations worldwide. …”
Get full text