Tea and depression by Klaus W. Lange, Yukiko Nakamura, Katharina M. Lange, Hui Zhao

“…However, the moderate antidepressive effects observed in healthy people are not necessarily indicative of possible clinical effects in major depressive disorder. Randomized controlled intervention studies are needed to establish a causal relationship between bioactive compounds in tea and depression.…”
Get full text

Trends in research on novel antidepressant treatments by Agnieszka Zelek-Molik, Ewa Litwa

“…Mood disorders, such as major depressive disorder and bipolar disorder, are among the most common mental illnesses and a leading cause of disability worldwide. …”
Get full text

Choosing to die with the help or by the hand of a doctor (medically-assisted death): Limitations and safety profiles by F. Cembrani, D. De Leo

“…The aim of the study: to consider a specific case of a patient with major depressive disorder and the role of doctors in informing the decision about medically assisted death. …”
Get full text

LSD and psilocybin for chronic nociplastic pain: A narrative review of the literature supporting the use of classic psychedelic agents in chronic pain by J Van Der Walt, R Parker

“…The new wave of research into psychedelics for major depressive disorder provides an opportunity to investigate and understand the potential for incorporating these drugs into chronic pain management pathways. …”
Get full text

Linguistic Analysis of Hindi-English Mixed Tweets for Depression Detection by Carmel Mary Belinda M J, Ravikumar S, Muhammad Arif, Dhilip Kumar V, Antony Kumar K, Arulkumaran G

“…According to recent studies, young adults in India faced mental health issues due to closures of universities and loss of income, low self-esteem, distress, and reported symptoms of anxiety and/or depressive disorder (43%). This makes it a high time to come up with a solution. …”
Get full text

Severe, but not moderate asthmatics share blood transcriptomic changes with post-traumatic stress disorder and depression. by Sandor Haas-Neill, Anna Dvorkin-Gheva, Paul Forsythe

“…There is growing recognition of an association between asthma and mood disorders including post-traumatic stress disorder (PTSD) and major depressive disorder (MDD). Although there are several hypotheses regarding the relationship between asthma and mental health, there is little understanding of underlying mechanisms and causality. …”
Get full text

Sex differences in slow-wave electroencephalographic activity (SWA) in adolescent depression by Robert Hoffmann, Roseanne Armitage, Graham Emslie, Jorge Lopez

“…Sleep disturbance, present in more than 90% of major depressive disorder (MDD) patients, are moderated by sex in adult MDD. …”
Get full text

Anxiolytic, Antidepressant, and Anticholinesterase Effects of Essential Oil from <i>Myrcia sylvatica</i> (G.Mey.) DC by Antônio Quaresma da Silva Júnior, Mariana Maciel Garcia, Wanderson da Silva Farias, Deise Juliane dos Anjos de Sousa, Adenilson de Sousa Barroso, Pablo Luis Baia Figueiredo, Gabriela B. dos Santos, Ricardo Bezerra de Oliveira, Rosa Helena Veras Mourão

“…These findings suggest that MsEO has potential therapeutic applications for anxiety and depression disorders, with additional anticholinesterase activity warranting further investigation in cognitive-related conditions.…”
Get full text

Deficient Autophagy in Microglia Aggravates Repeated Social Defeat Stress-Induced Social Avoidance by Mai Sakai, Zhiqian Yu, Ryo Hirayama, Masa Nakasato, Yoshie Kikuchi, Chiaki Ono, Hiroshi Komatsu, Miharu Nakanishi, Hatsumi Yoshii, David Stellwagen, Tomoyuki Furuyashiki, Masaaki Komatsu, Hiroaki Tomita

“…Major depressive disorder (MDD) is associated with repeated exposure to environmental stress. …”
Get full text

Chinese version of the Perth Alexithymia Questionnaire: psychometric properties and clinical applications by Wei Wei, Zhe Zhang, Lin Zhu, Qian Zhang, Xin-Lu Cai, Qingying Ye, Ke Ni, Minmin Yin, David A. Preece, Bao-Ming Li

“…In Study 2, four groups, including a major depressive disorder (MDD) group (n=50), a matched healthy control group for MDD (n=50), a subclinical depression group (n=50) and a matched healthy control group for subclinical depression (n=50), were recruited. …”
Get full text

An Active Inference Model of the Optimism Bias by Elizabeth L. Fisher, Christopher J. Whyte, Jakob Hohwy

“…Associated with improved quality of life, optimism bias is considered to be adaptive and is a promising avenue of research for mental health interventions in conditions where individuals lack optimism such as major depressive disorder. Here we lay the groundwork for future research on optimism as an intervention by introducing a domain general formal model of optimism bias, which can be applied in different task settings. …”
Get full text

The Efficacy of Pramipexole, a Dopamine Receptor Agonist, as an Adjunctive Treatment in Treatment-Resistant Depression: An Open-Label Trial by Hiroaki Hori, Hiroshi Kunugi

“…Although the efficacy of adjunctive pramipexole treatment has been demonstrated in treatment-resistant bipolar depression, such data are scarce for major depressive disorder (MDD). We recruited 17 patients with DSM-IV major depressive episode who have failed to respond to previous treatment with a selective serotonin reuptake inhibitor. …”
Get full text

A network-based analysis anticipates time to recovery from major depression revealing a plasticity by context interplay by Claudia Delli Colli, Aurelia Viglione, Silvia Poggini, Francesca Cirulli, Flavia Chiarotti, Alessandro Giuliani, Igor Branchi

“…Abstract Predicting disease trajectories in patients with major depressive disorder (MDD) can allow designing personalized therapeutic strategies. …”
Get full text

Beyond metabolic messengers: Bile acids and TGR5 as pharmacotherapeutic intervention for psychiatric disorders by Arief Gunawan Darmanto, Ting-Lin Yen, Jing-Shiun Jan, Tran Thanh Duy Linh, Rajeev Taliyan, Chih-Hao Yang, Joen-Rong Sheu

“…We detail the synthesis and systemic functions of bile acids, their transformation by gut microbiota, and their impact across various neuropsychiatric disorders, including major depressive disorder, general anxiety disorder, schizophrenia, autism spectrum disorder, and bipolar disorder. …”
Get full text

Work productivity (absenteeism and presenteeism) in persons with common mental disorders: An observational study from South India by Manjunatha B. Kondapura, Narayana Manjunatha, Anil Kumar M. Nagaraj, Samir K. Praharaj, Channaveeraachari N. Kumar, Suresh B. Math, Girish N. Rao

“…Materials and Methods: This was a cross-sectional observational study on 220 subjects (110, 58, and 52 patients with depressive disorder, anxiety disorders, and somatoform disorders, respectively), recruited through purposive sampling. …”
Get full text

Factors related to painful somatic symptoms in patients with depression: The role of gender and anhedonia by A. Pérez-Morenilla, A. Salazar, I. Failde, F. González-Sáiz, J.A. Micó

“…Background: Pain is common in Major Depressive Disorder (MDD), but other related factors have received scant attention. …”
Get full text

Effect of Vitamin B12 supplementation in late-life depression: A randomized controlled trial by Pooja Misal, Shrikant Srivastava, Akanksha Sonal, Vivek Agarwal, Wahid Ali

“…Structured assessment of depressive disorder was carried out on days 0, 14, and 28, using hamilton rating scale for depression (HAM-D) and Geriatric Depression Scale Hindi version (GDS-H). …”
Get full text

Psychiatric comorbidity in patients with migraine: A standardized interview-based study by Preeti Sharma, Santosh Kumar, Vidhata Dixit, Chandra Shekhar Sharma, Suprakash Chaudhury

“…Results: Total Patients recruited were 146 out of which 70.5% had a psychiatric comorbidity. Depressive disorder (17.1%) was the most common while delusional disorder (4.1%) was the least common psychiatric disorder comorbid with migraine. …”
Get full text

Bupropion Mediated Effects on Depression, Attention Deficit Hyperactivity Disorder, and Smoking Cessation by Austin Clark, Brendan Tate, Bretton Urban, Ryan Schroeder, Sonja Gennuso, Shahab Ahmadzadeh, David McGregor, Brook Girma, Sahar Shekoohi, Alan D. Kaye

“…Our review demonstrates that bupropion is superior to placebo and non-inferior to SSRIs such as escitalopram in treating major depressive disorder. More research is needed to determine positive patient-centered outcomes such as increases in quality of life. …”
Get full text

Cognitive Behavior Therapies (CBT) in Childhood and Adolescent Mood Disorders and Anxiety Disorders: A Review by Nilg&uuml;n &Ouml;ngider

“…PsycINFO, Medline and the Turkish Psychiatric databases were searched, using the key words &#145;depressive disorder&#146;, &#145;anxiety disorders&#146; &#145;cognitive behavioural treatment&#146;. …”
Get full text