Comparison of the efficacy and safety of bupropion versus aripiprazole augmentation in adults with treatment-resistant depression: a nationwide cohort study in South Korea by Dong Yun Lee, Rae Woong Park, Soo Min Jeon

“… Abstract Background Treatment-resistant depression (TRD) affects 10–30% of patients with major depressive disorder, leading to increased comorbidities, higher mortality, and significant economic and social burdens. …”
Get full text

Avolition Characterizes the Chronic Fatigue Experienced in Quiescent Inflammatory Bowel Disease by Tristan Gabriel-Segard, Margherita Boltri, Mathilde Barrau, Catherine Massoubre, Stéphane Paul, Xavier Roblin

“…This difference is independent of current depressive disorder and previous history of depressive disorder. …”
Get full text

Duloxetine Contributing to a Successful Multimodal Treatment Program for Peripheral Femoral Neuropathy and Comorbid ‘Reactive Depression’ in an Adolescent by Ludmyla Kachko, Shiri Ben Ami, Alon Liberman, Einat Birk, Sefi Kronenberg

“…In the United States, duloxetine has been approved for the treatment of major depressive disorder, diabetic peripheral neuropathic pain and fibromyalgia in the adult population. …”
Get full text

An Illustration of Interpersonal Psychotherapy for Perinatal Depression by Huey Jing Renee Tan

“…This is a case of a 38-year-old married woman presenting with major depressive disorder one month after the birth of her third child. …”
Get full text

Urinary Incontinence due to Overactive Detrusor Muscle: A Rare Side Effect of Venlafaxine by Vithyalakshmi Selvaraj, Palanikumar Gunasekar, Suneel Kumar, Imad Alsakaf

“…A 66-year-old Caucasian male with prior history of major depressive disorder developed UI within a week of starting venlafaxine 75 mg per day. …”
Get full text

Psychogenic Nonepileptic Seizures (PNES) in the Setting of Trauma and Schizophrenia by Sikander Chohan, Ali Chohan, Muhamid Asif

“…The etiology of PNES is complex. Major depressive disorder and generalized anxiety disorder are common comorbid conditions in these patients. …”
Get full text

A study of impulsivity and adverse childhood experiences in a population health setting by Robert W. Read, Karen A. Schlauch, Gai Elhanan, Iva Neveux, Stephanie Koning, Takesha Cooper, Takesha Cooper, Joseph J. Grzymski, Joseph J. Grzymski

“…Among these, 44 were related to mental health diagnoses, including major depressive disorder (MDD). Kaplan–Meier survival estimates characterized the differences in the lifetime predicted probability between high and low impulsivity for major depressive disorder and essential hypertension. …”
Get full text

Homicide and Associated Steroid Acute Psychosis: A Case Report by G. Airagnes, C. Rouge-Maillart, J.-B. Garre, B. Gohier

“…The clinical course was complicated by a major depressive disorder with suicidal ideas, due to the steroid stoppage, the leukemia progressed, and by a sudden onset of a fatal pulmonary embolism. …”
Get full text

An Observational Study to Assess Smartphone Usage in Patients of Anxiety and Depression by Aditya Satish Nair, Ankit Halder, Roma Shahani, Nikhil Avula, Devavrat Harshe, Gurudas Harshe

“…Background: Anxiety and depression disorders are among the most common psychiatric illness in the community and primary care. …”
Get full text

Mental health in children with and without ADHD: the role of physical activity and parental nativity by David Adzrago, Saanie Sulley, Faustine Williams

“…Conclusions Physical activity was associated with lower risks of diagnosed with anxiety/depression disorder among children, especially children without ADHD and those with immigrant parents. …”
Get full text

Clinical and Biochemical Manifestations of Depression: Relation to the Neurobiology of Stress by Phillip W. Gold, Rodrigo Machado-Vieira, Maria G. Pavlatou

“…Major depressive disorder (MDD) is a chronic, recurrent, and severe psychiatric disorder with high mortality and medical comorbidities. …”
Get full text

Hippocampal Neurogenesis and Antidepressive Therapy: Shocking Relations by Peter Rotheneichner, Simona Lange, Anna O’Sullivan, Julia Marschallinger, Pia Zaunmair, Christian Geretsegger, Ludwig Aigner, Sebastien Couillard-Despres

“…This review revisits recent findings on the close relation between the mode(s) of action of electroconvulsive therapy (ECT), a powerful intervention used as second-line treatment of major depression disorders, and the neurogenic response to ECT. …”
Get full text

The Trifecta of Industry, Academic, and Health System Partnership to Improve Mental Health Care Through Smartphone-Based Remote Patient Monitoring: Development and Usability Study by C Neill Epperson, Rachel Davis, Allison Dempsey, Heinrich C Haller, David J Kupfer, Tiffany Love, Pamela M Villarreal, Mark Matthews, Susan L Moore, Kimberly Muller, Christopher D Schneck, Jessica L Scott, Richard D Zane, Ellen Frank

“…Patients with a diagnosis of major depressive disorder, bipolar disorder, or other mood disorder were contacted online and enrolled for a 6-week trial of Rhythms. …”
Get full text

EVALUATION OF THE THERAPEUTIC EFFECTS OF SALVIA ROSMARINUS ESSENTIAL OIL ON NERVOUS SYSTEM DISORDERS by Malina Mihaela Visternicu, Viorica Rarinca, Vasile Burlui, Alin Ciobica

“…This review explores the therapeutic potential of rosemary in alleviating nervous system disorders such as Alzheimer's disease (AD), major depressive disorder (MDD), epilepsy, Parkinson's disease (PD), addiction, and attention-deficit hyperactivity disorder (ADHD). …”
Get full text

New Therapeutic Targets for Mood Disorders by Rodrigo Machado-Vieira, Giacomo Salvadore, Nancy DiazGranados, Lobna Ibrahim, David Latov, Cristina Wheeler-Castillo, Jacqueline Baumann, Ioline D. Henter, Carlos A. Zarate

“…Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. …”
Get full text

Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity by Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N. Lundström, Jian Zeng, Naomi R. Wray, Yi Lu, Patrick F. Sullivan, Jens Hjerling-Leffler

“…By integrating genomic insights from genome-wide association studies with a comprehensive single-cell transcriptomic atlas of the adult human brain, we prioritized specific neuronal clusters significantly enriched for the SNP-heritabilities for schizophrenia, bipolar disorder, and major depressive disorder along with intelligence, education, and neuroticism. …”
Get full text

Understanding adolescent depression in Singapore: a qualitative study by Ngar Yee Poon, Cheryl Bee-Lock Loh

“…Methods: Semi-structured interviews were conducted with 14 adolescents, aged between 13 and 19 years, who were diagnosed and treated for diagnostic and statistical manual of mental disorders, 5th edition major depressive disorder and clinically judged to have recovered at the time of recruitment. …”
Get full text

Prediction of individual patient outcomes to psychotherapy vs medication for major depression by Devon LoParo, Boadie W. Dunlop, Charles B. Nemeroff, Helen S. Mayberg, W. Edward Craighead

“…Abstract Treatments for major depressive disorder (MDD) include antidepressant medications and evidence-based psychotherapies, which are approximately equally efficacious. …”
Get full text

Autobiographical Memory Disturbances in Depression: A Novel Therapeutic Target? by Cristiano A. Köhler, André F. Carvalho, Gilberto S. Alves, Roger S. McIntyre, Thomas N. Hyphantis, Martín Cammarota

“…Major depressive disorder (MDD) is characterized by a dysfunctional processing of autobiographical memories. …”
Get full text

From air to mind: unraveling the impact of indoor pollutants on psychiatric disorders by German Torres, Ryia T. Subbaiah, Riya A. Sood, Joerg R. Leheste

“…This evidence comes primarily from occupational work studies in humans, with indoor occupations being the most important sources of airborne pollutants affecting neural circuits implicated in mood disorders (e.g., major depressive disorder and bipolar disorder). The current mini review brings together recent findings of indoor airborne pollution from different fields of research, including genetics, neuropathology, and neuroimaging, for gauging underlying physiological mechanisms leading to emotional disturbances that impact nearly all aspects of human behavior. …”
Get full text