Synthetic Vesicle-Based Drug Delivery Systems for Oral Disease Therapy: Current Applications and Future Directions by Pengjie Huang, Weichang Li, Jiezhong Guan, Yibing Jia, Dan Wang, Yurun Chen, Niu Xiao, Songyue Ou, Yan Wang, Bo Yang

“…Oral diseases such as dental caries, periodontitis, and oral cancer are prevalent and present significant challenges to global public health. …”
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Remineralising Effects of L-arginine Fluoride Mouthwash versus Sodium Fluoride Mouthwash: A Protocol of an In-vitro Study by Anjori Ajinkya Raut, Punit Ratnakar Fulzele

“…Introduction: Preventing dental caries and maintaining oral health are important for children’s quality of life, as they profoundly impact overall well being, self-esteem and long-term health outcomes. …”
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Antimicrobial effect of silver diamine fluoride (SDF) in arresting dentine caries of permanent teeth: A Systematic review [version 1; peer review: 2 approved] by Mamata Hebbal, Albandri Mohammed Alowid, Praveen Jodalli, Shahad Saad Alkait, Ghadeer Ghalab Almutairi, Fatimah Salim Almufarji

“…Future research, including long-term clinical trials, is warranted to elucidate optimal dosage regimens and therapeutic approaches for the routine application of SDF in managing dental caries.…”
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The Effect of Ca and Mg Concentrations and Quantity and Their Correlation with Caries Intensity in School-Age Children by Milaim Sejdini, Kastriot Meqa, Nora Berisha, Ekrem Çitaku, Nora Aliu, Sokol Krasniqi, Sami Salihu

“…In the development of dental caries, the relationship between demineralization and remineralization is influenced by the presence of saliva, which facilitates the transportation of ions, oral bacteria, and fermentable carbohydrates to the exposed surfaces of teeth. …”
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Impact of phytoconstituents on oral health practices: a post COVID-19 observation by Harsh Kumar, Reena Singh, Daljeet Singh Dhanjal, Chirag Chopra, Natália Cruz-Martins, Gheyath K. Nasrallah, Amin F. Majdalawieh, Sivakumar Manickam, Shahida Anusha Siddiqui, Dinesh Kumar, Indu Sharma, Varun Sharma

“…Appropriate oral hygiene significantly reduces the possibility of oral infections. However, dental caries and periodontal diseases are major oral health issues causing chronic diseases due to poor oral health. …”
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The impact of food-based incentive behaviors on oral health among Saudi children: a cross-sectional study by Yasir Dilshad Siddiqui, Saud Hamdan Almaeen, Ahmed Shawkat Hashem, Ahmed Ali Ahmed Almuntashiri, Mohammed Nadeem Baig, Abdullah Hammad Alshammari, Rital Jamal Alwaqid, Haifa Ali Almutairi, Raha Ahmed, Rakhi Issrani, Farooq Ahmad Chaudhary

“…Abstract Background Childhood dental caries is a common and significant oral health issue globally, resulting in pain, infection, and difficulties in eating and speaking. …”
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Exploring the Association Between Third Molar Agenesis and Carabelli Traits: A Cross-Sectional Study by Isabela Ribeiro Madalena, Heloisa Guimarães Resende, Ariane Beatriz Blancato, Maria Angélica Hueb de Menezes-Oliveira, Flares Baratto-Filho, Poliana Ferreira Santos, Camila Paiva Perin, Thais Vilalba Paniagua Machado do Nascimento, Peter Proff, Christian Kirschneck, César Penazzo Lepri, Erika Calvano Küchler

“…Teeth with cavitated lesions of dental caries, occlusal wear, restorations, and evident dental deformities were not included in the evaluation. …”
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Oral health-related quality of life of community-dwellers in the canton of Bern, Switzerland by Roberta Borg-Bartolo, Andrea Roccuzzo, Christian Tennert, Maria Prasinou, Maurus Jäggi, Pedro Molinero-Mourelle, Michael M. Bornstein, Guglielmo Campus

“…Data were collected by a questionnaire (demographic factors, medical history, oral health behavior, dental patient-reported outcomes [dPROs]) and a clinical examination (dental caries, periodontal disease, oral hygiene, mastication). dPROs were evaluated using the OHRQoL-questionnaire Geriatric Oral Health Assessment Index with items related to four domains: functional limitations, pain and discomfort, psychological impact, behavioral impact. χ2 tests, Cochrane Armitage trend tests and binary logistic regression were performed with P < 0.05 statistical significance. …”
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Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data by Luyang Su, Ren Xu, Yanan Ren, Shixia Zhao, Weilan Liu, Zeqing Du

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ2, 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ2, 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ2, 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ2, 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ2, 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ2, 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.ConclusionOur findings align with clinical observations, highlighting the emergence of previously unreported AE signals associated with MPA and their demographic and TTO characteristics. …”
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Evaluation of oral health status in patients with type 2 diabetes by Tahmineh Khoshbakhti, Vajehallah Raeesi, Gholamreza Sharifzadeh, Leili Alizadeh

“…One of the most significant symptoms reported by diabetic patients is dry mouth, which results in reduced saliva buffering capacity and an increased risk of dental caries. So, the purpose of this study was to compare the oral health indicators of type 2 diabetic patients with non-diabetic controls. …”
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Surface prereacted glass-ionomer particles incorporated into resin composites promote biocompatibility for restoration of subgingival dental defects by Yueyi Yang, Jing Huang, Xuchen Hu, Meiling Jing, Yujie Zhang, Chenci Xu, Wenduo Tan, Xiaoyu Liu, Chenguang Niu, Zhengwei Huang

“…Subgingival dental defects are common in clinical practice among patients with deep dental caries and dental fractures. These defects commonly accompany lesions involving marginal alveolar bone loss and gingival recession, and their clinical management is challenging. …”
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