Clinical significance of HER2 in urothelial carcinoma and analysis of its correlation with glycolytic metabolic characteristics by Andong Guo, Andong Guo, Chenrui Wu, Jishuang Cao, Kejia Zhu, Kejia Zhu, Sentai Ding, Sentai Ding

“…Subgroup analyses confirmed the consistency of the relationship between HER2 expression and LDH levels across different demographics and lifestyle factors.ConclusionOur findings confirm the significant role of HER2 as a prognostic marker and therapeutic target in UC. …”
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Study protocol for the COPE study: COVID-19 in Older PEople: the influence of frailty and multimorbidity on survival. A multicentre, European observational study by Thomas Lee, Sandeep Singh, Phyo Kyaw Myint, Sheila Jones, Ben Carter, Susan Moug, Terry Quinn, Michael Thomas, Emma Bhatti, Angeline Price, Fenella Barlow-Pay, Siobhan Duffy, Lyndsay Pearce, Arturo Vilches-Moraga, Michael Stechman, Philip Braude, Emma Mitchell, Alessia Verduri, Kathryn McCarthy, Jonathan Hewitt, Charlotte Davey, Kiah Lunstone, Alice Cavenagh, Charlotte Silver, Thomas Telford, Rebecca Simmons, Dolcie Paxton, Francis Rickard, Mark Holloway, James Hesford, Tarik Jichi, Norman Galbraith, Jenny Edwards, Carly Bisset, Ross Alexander, Abigail Ingham, Roxanna Short, Aine McGovern, Jemima Collins, Eilidh Bruce, Alice Einarsson, Enrico Clini, Giovanni Guaraldi, Madeline Garcia, Shefali Sangani, Thomas Kneen, George Kyriakopoulos, Denise Tan

“…Introduction This protocol describes an observational study which set out to assess whether frailty and/or multimorbidity correlates with short-term and medium-term outcomes in patients diagnosed with COVID-19 in a European, multicentre setting.Methods and analysis Over a 3-month period we aim to recruit a minimum of 500 patients across 10 hospital sites, collecting baseline data including: patient demographics; presence of comorbidities; relevant blood tests on admission; prescription of ACE inhibitors/angiotensin receptor blockers/non-steroidal anti-inflammatory drugs/immunosuppressants; smoking status; Clinical Frailty Score (CFS); length of hospital stay; mortality and readmission. …”
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Patient participation in free cataract surgery: a cross-sectional study of the low-income elderly in urban China by Bo Qu, Hui Chen, Xuhua Tan, Xiaohang Wu, Haotian Lin, Zhenzhen Liu, Lixia Luo, Bo Zhang, Erping Long, Duoru Lin, Weirong Chen, Yizhi Liu, Haofeng Jiang, Jingjing Chen, Zhuoling Lin, Xiaoyan Li, Jinzhu Tang, Yingfen Lin

“…Data were collected on patient demographics, resources, health conditions, reasons for undergoing the free surgery and overall evaluation of the free cataract surgery programme.Results Among the 833 participants, the mean surgical age was 76.85±7.46 years (95% CI 76.34 to 77.36), and the male to female ratio was 385:448. …”
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Piloting of a Screen-Triage-Treat Surgical Approach Model for Management of Anal Cancer in Liberia by Christopher W. Reynolds, Whitney Lieb, Andrea Schecter, Michael M Gaisa, Stephen K. McGill, Evans L. Adofo, Ann Marie Beddoe

“…A survey validated by SAIL experts assessed demographics and sexual risk factors. Participants underwent anal self-swabbing for high-risk human papillomavirus (HPV) and offered human immunodeficiency virus (HIV) testing. …”
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What Can Be Done to Improve the Mental Health of University Students? Identifying Determinants of Psychological Distress at an Australian University by Patrick J. Owen, Shane A. Kavanagh, Anthony D. LaMontagne

“…Individual determinants included socio-demographics and financial, housing, and employment status. …”
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Development and validation of a prediction model for acute kidney injury following cardiac valve surgery by Xiaotong Jia, Jun Ma, Zeyou Qi, Dongni Zhang, Junwei Gao

“…Using these factors, we developed a risk prediction model for AKI after cardiac valve surgery and conducted external validation.MethodsOur retrospective study recruited 497 adult patients undergoing cardiac valve surgery as a derivation cohort between February and August 2023. Patient demographics, including medical history and perioperative clinical information, were acquired, and patients were classified into one of two cohorts, AKI and non-AKI, according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. …”
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Reconstructive trends and complications following parotidectomy: incidence and predictors in 11,057 cases by Cory Donovan Bovenzi, Peter Ciolek, Meghan Crippen, Joseph M. Curry, Howard Krein, Ryan Heffelfinger

“…Univariate and multivariate analysis was utilized to determine associations between pre- and perioperative variables with patient outcomes. Preoperative demographics, surgical indications, and common medical comorbidities were collected. …”
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The Impact of EGDT on Sepsis Mortality in a Single Tertiary Care Center in Lebanon by Christopher El Khuri, Gilbert Abou Dagher, Ali Chami, Ralph Bou Chebl, Tarek Amoun, Rana Bachir, Batoul Jaafar, Nesrine Rizk

“…Data from the EHR were retrieved about patients’ demographics, medical comorbidities, and periresuscitation parameters. …”
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Low skeletal muscle mass as a proxy marker of sarcopenia is a risk factor for major complications in older patients undergoing curative colon resections for colon cancer by İsmail Tırnova, Maya Gasimova, Hatice Akay, Çağla Sarıtürk, Aslıhan Güven Mert, Özlem Yenidünya, Feza Yarbuğ Karakayalı

“…We aimed to investigate the effects of skeletal muscle mass index (SMMI) on postoperative complications, overall survival (OS), and disease-free survival (DFS) in older patients with colon cancer who underwent elective curative colon resections.Materials and methodsPatients over 65 years old with stage I-III colon cancer who underwent elective curative colon resections between January 2015 and December 2023 were included in this single-center retrospective longitudinal study. Demographics, comorbidities, laboratory data, pathological features, malignant lymph node ratio (MLNR), OS, and DFS were recorded. …”
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Disposition of emergency department patients presenting with angiotensin-converting enzyme inhibitor-induced angioedema by Blake Briggs, David Cline, Iltifat Husain

“…Our secondary objective was to evaluate unique patterns in those with ACEI-induced angioedema at a tertiary referral center, including demographics, details of those requiring intubation, length of inpatient stay, and allergy documentation. …”
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History of coronary heart disease increased the mortality rate of patients with COVID-19: a nested case–control study by Yaping He, Lei Xu, Tian Gu, Qiao Chu, Zhangsheng Yu, Botao Fa, Anqi Li, Ruijun Wu

“…Objective Evaluate the risk of pre-existing comorbidities on COVID-19 mortality, and provide clinical suggestions accordingly.Setting A nested case–control design using confirmed case reports released from the news or the national/provincial/municipal health commissions of China between 18 December 2019 and 8 March 2020.Participants Patients with confirmed SARS-CoV-2 infection, excluding asymptomatic patients, in mainland China outside of Hubei Province.Outcome measures Patient demographics, survival time and status, and history of comorbidities.Method A total of 94 publicly reported deaths in locations outside of Hubei Province, mainland China, were included as cases. …”
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Characterizing avocado production systems for Ugandan exports: the need for consolidation and support for sustainable development by Peter Sseruwagi, Peter Sseruwagi, Edouard Lehmann, Paul Sigombe, Gabriel Ddamulira, Jan Willem Van Casteren, Pieterjan De Bauw

“…Farming systems and dynamics were characterized by assessing demographics, economic data, marketing, farmer organization, and farming practices including soil and nutrient management, irrigation, pest and disease control, and post-harvest management. …”
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Effects of the Implementation of an Emergency Surgical Pattern in Patients with Rhegmatogenous Retinal Detachment: A Retrospective Observational Study by Ziye Chen, Kai Gao, Kunbei Lai, Wenbin Zheng, Jizhu Li, Yaping Liu, Baoyi Liu, Xiaoyue Wei, Yuan Ma, Zitong Chen, Rebiya Tuxun, Tao Li

“…A total of 140 patients (140 eyes) in the routine inpatient surgery group were collected at the fundus disease department between January 2019 and December 2019, and 206 patients (208 eyes) in the emergency surgery group were collected at the ophthalmic emergency department between January 2021 and December 2021. Demographics, best-corrected visual acuity (BCVA) expressed as the logarithm of the minimum angle of resolution (logMAR), the status of the macula before surgery, time to presentation, treatment interval, and postoperative BCVA measured at least three months follow-up were compared. …”
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Is surgery superior for distal ulna fractures? a comprehensive systematic review and meta-analysis by Zakaria Chabihi, Brahim Demnati, Mohamed Moussadiq, Tariq Aalil, Yassine Fath El Khir, El Mehdi Boumediane, Mohamed Amine Benhima, Imad Abkari

“…Studies were selected based on predefined inclusion and exclusion criteria, and data were extracted on patient demographics, fracture characteristics, treatment details, functional outcomes, patient-reported outcomes, complications, and follow-up duration. …”
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Impact of noninsulin-dependent diabetes mellitus (level of control) on sex hormone profile and erectile function by Abdullah A. Khawaji, Hossam S. El-Tholoth, Muath A. Albarakati, Bander A. Binjabaan, Abdulaziz Alzahrani, Abdulmajeed Althobity, Abdulmalik Almardawi, Khaled Bedaiwi, Mussa AlNuami

“…Retrieved data include patient’s demographics, body mass index (BMI), hormonal profile, Complete Blood Count (CBC), lipid profile, prostate-specific antigen (PSA), urate, Vitamin D level, and the severity of ED as assessed by the International Index of Erectile Function (IIEF) scores. …”
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Hospital Financial Burden of Surgical Procedures for Periprosthetic Total Hip Arthroplasty Infection by Jesus M. Villa, MD, Tejbir S. Pannu, MD, MS, Robert B. Eysler, BA, Vivek Singh, MD, MPH, Alison K. Klika, MS, Carlos A. Higuera, MD

“…Methods: Retrospective chart review of 596 unilateral THA reoperations (473 patients) performed at a single institution (January 2015 to November 2020). Demographics, professional (ie, physicians), and technical (ie, room, implants) hospital charges per case were compared between 6 different surgery types: (1) aseptic revision (control; n = 364); (2) debridement, antibiotics, and implant retention (n = 11); (3) explantation (n = 145); (4) spacer exchange (n = 7); (5) 2-stage reimplantation (n = 59); and (6) 1-stage reimplantation (n = 10). …”
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Actors influencing cancer-related fatigue and the construction of a risk prediction model in lung cancer patients by Mei-Ning Zhang, Yi-Chen Zhou, Zhu Zeng, Cun-Liang Zeng, Bo-Tao Hou, Gui-Rong Wu, Qiao Jiao, Dai-Yuan Ma

“…A questionnaire survey was conducted using the Revised Piper Fatigue Scale (PFS-R), Pittsburgh Sleep Quality Index (PSQI), and Hospital Anxiety and Depression Scale (HADS) to collect data on patient demographics and sociological characteristics, disease-related information, physiological indicators, sleep quality, mental health, and other relevant factors. …”
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Examining factorial validity and internal consistency of Professional Quality of Life (ProQoL-9) among care aides working in Long-term Care (LTC) by Seyedehtanaz Saeidzadeh, Anni Wang, Yinfei Duan, Isaiah Hipel, Peter G. Norton, Carole A. Estabrooks

“…We used TREC surveys containing information on demographics, characteristics of LTC homes (e.g., ownership model), and the ProQoL-9. …”
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Severe Hepatotoxicity in Mushroom Poisoning by Lepiota brunneoincarnata from Complete Recovery to Liver Transplantation: A Case Series with Review on Liver Function Tests and Liver... by Mohammad Hossein Anbardar, Neda Soleimani, Kourosh Kazemi, Zahra Jafarpour, Mahsa Hasani, Sahand Mohammadzadeh, Parnia Torfehnezhad, Sedighe Jafarian, Mahsa Farhadi, Mina Salari Sardari

“…Method. We provided demographics, clinicopathological characteristics, applied treatments, and outcomes of mushroom poisoning by Lepiota species in a series of 18 cases that were referred from Kermanshah and Lorestan provinces to Abu-Ali-Sina Hospital, Shiraz, Iran. …”
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Migraine and subsequent chronic kidney disease risk: a nationwide population-based cohort study by Ming-Ju Wu, Chew-Teng Kor, Chia-Chu Chang, Shuo-Chun Weng, Chia-Lin Wu, Ping-Fang Chiu, Der-Cherng Tarng

“…All the participants were registered in the National Health Insurance Research Database.Participants Finally, data from 7156 subjects with migraine and 7156 propensity-score-matched control subjects were analysed.Primary outcome measure We used Cox proportional hazards regression to estimate adjusted HRs for incident CKD; subgroup analyses were performed to assess the interactive effects of migraine with demographics, comorbidities and long-term medications.Results The incidence of CKD was higher in the migraine group than in the control group. …”
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