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501
Consultations on driving in people with cognitive impairment in primary care: A scoping review of the evidence.
Published 2018-01-01“…<h4>Participants</h4>PCPs or their equivalent and/ or individuals with cognitive impairment across the spectrum of mild cognitive impairment to dementia.<h4>Measurements</h4>Systematic search of Medline, Cinahl, PsychINFO, Academic Search Complete, Psychological and Behavioural Sciences Collection, SocIndex and Social Sciences FT were conducted. …”
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502
Dietary Fatty Acids and Predementia Syndromes
Published 2009-01-01“…Therefore, at present, no definitive dietary recommendations on fish and unsaturated fatty acids consumption, or lower intake of saturated fat, in relation to the risk for dementia and cognitive decline are possible.…”
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503
Transformative Service Research and the role of service robots: a bibliometric analysis
Published 2025-01-01“…The analysis of several use cases of service robots in elderly care is carried out in the article to highlight the importance of using this service in cases of great importance, such as in cases of dementia. Cultural sensitivity and personalization of robots emerged as essential factors for increasing user acceptance and scalability, particularly in diverse healthcare environments. …”
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504
Estimating the potential health effects of cleaner air in the initial stages of the COVID-19 pandemic: a study in Malmö, Sweden
Published 2024-12-01“…If sustained, such improvements could lead to an estimated 1–3% decrease in premature deaths, a 2% decrease in preeclampsia cases, a 6% decrease in low birthweight children, a 4% decrease in bronchitis cases among children, a 2% decrease in asthma cases, a 0.2% decrease in hospital admissions for respiratory diagnoses, and an estimated 11% decrease in dementia cases annually. Conclusion The findings illustrate the potential for enhanced health in Malmö due to improved air quality. …”
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505
Emerging targets of α-synuclein spreading in α-synucleinopathies: a review of mechanistic pathways and interventions
Published 2025-01-01“…Abstract α-Synucleinopathies constitute a spectrum of neurodegenerative disorders, including Parkinson’s disease (PD), Lewy body dementia (LBD), Multiple System Atrophy (MSA), and Alzheimer’s disease concurrent with LBD (AD-LBD). …”
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506
Impact of Alzheimer’s Disease on Caregivers in the United States
Published 2022-08-01“…As patients’ symptoms of dementia continue to worsen, they gradually grow more limited in their independence. …”
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507
Brain targeting based nanocarriers loaded with resveratrol in Alzheimer's disease: A review
Published 2023-05-01“…Abstract Alzheimer's disease (AD) is one of the chief neurological difficulties in the aged population, identified through dementia, memory disturbance, and reduced cognitive abilities. β‐amyloid (Aβ) plaques aggregations, generation of reactive oxygen species, and mitochondrial dysfunction are among the major signs of AD. …”
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508
Advanced Magnetic Resonance Imaging for Early Diagnosis and Monitoring of Movement Disorders
Published 2025-01-01“…These techniques enable earlier and more accurate differentiation of movement disorders, including Parkinson’s disease, progressive supranuclear palsy, multiple system atrophy, corticobasal degeneration, Lewy body and frontotemporal dementia, Huntington’s disease, and dystonia. Furthermore, MRI provides objective metrics for tracking disease progression and assessing therapeutic efficacy, making it an indispensable tool in clinical trials. …”
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509
The antioxidant potential of bacoside and its derivatives in Alzheimer's disease: The molecular mechanistic paths and therapeutic prospects
Published 2025-06-01“…The key physiological dysfunctions linked to tau aggregates, which contribute to dementia and behavioral inconsistencies, include the formation of reactive oxygen species, augmented neuronal swelling, and neurotoxicity. …”
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510
Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina
Published 2025-01-01“…Abstract Over recent years, the retina has been increasingly investigated as a potential biomarker for dementia. A number of studies have looked at the effect of Alzheimer’s disease (AD) pathology on the retina and the associations of AD with visual deficits. …”
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511
Mutations in human prion-like domains: pathogenic but not always amyloidogenic
Published 2024-12-01“…To date, over 60 mutations targeting the LCDs of hnRNPs have been identified and associated with a spectrum of neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer’s disease (AD). The cryo-EM structures of pathological and functional fibrils formed by different hnRNPs have been recently elucidated, including those of hnRNPA1, hnRNPA2, hnRNPDL-2, TDP-43, and FUS. …”
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512
Identification of Potential Herbal Inhibitor of Acetylcholinesterase Associated Alzheimer’s Disorders Using Molecular Docking and Molecular Dynamics Simulation
Published 2014-01-01“…Additionally, acetylcholinesterase (AChE) is the target for many Alzheimer’s dementia drugs which block the function of AChE but have some side effects. …”
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513
Recognizing Cognitive and Psychiatric Changes in the Post-Highly Active Antiretroviral Therapy Era
Published 2012-01-01“…Specifically addressed in the present review are the International HIV Dementia Scale, a novel screening equation and algorithm for HAND, as well as brief, validated, verbal questionnaires for detection of depression and substance abuse. …”
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514
Influence of immune cells and inflammatory factors on Alzheimer’s disease axis: evidence from mediation Mendelian randomization study
Published 2025-02-01“…Abstract Background Alzheimer’s disease (AD) is one of the most common forms of dementia in the elderly, characterized by progressive neurodegeneration. …”
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515
Transforming Alzheimer’s Disease Diagnosis: Implementing Vision Transformer (ViT) for MRI Images Classification
Published 2025-01-01“… Alzheimer’s disease (AD) is a progressive neurological disorder and the leading cause of dementia, accounting for 60-80% of cases. Early detection of AD is crucial for timely intervention, as the disease significantly impacts cognitive functions and daily activities. …”
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516
Diogenes Syndrome: A Case Report
Published 2013-01-01“…These patients may have psychiatric disorders like paranoid disorders, mood affection, or temporofrontal dementia. Subjects are mainly the elderly but few cases in younger age group of patients have also been reported. …”
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517
Oligonucleotide-Based Therapy for FTD/ALS Caused by the C9orf72 Repeat Expansion: A Perspective
Published 2013-01-01“…Amyotrophic lateral sclerosis (ALS) is a progressive and lethal disease of motor neuron degeneration, leading to paralysis of voluntary muscles and death by respiratory failure within five years of onset. Frontotemporal dementia (FTD) is characterised by degeneration of frontal and temporal lobes, leading to changes in personality, behaviour, and language, culminating in death within 5–10 years. …”
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518
APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice
Published 2025-01-01“…Promotion of physical activity may therefore be particularly important to improve cerebrovascular function and reduce dementia risk in APOE4 carriers.…”
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519
The role of microRNAs in learning and long-term memory
Published 2020-12-01“…Moreover, impaired microRNA biogenesis is one of the causes of the pathogenesis of mental disorders, neurodegenerative illnesses and senile dementia, which are often accompanied by deterioration in the learning ability and by memory impairment. …”
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520
Metabolic Derangements Contribute to Reduced sRAGE Isoforms in Subjects with Alzheimer’s Disease
Published 2018-01-01“…Cognitively healthy elderly and AD participants with and without type 2 diabetes (n=135) were stratified according to the clinical dementia rating (CDR; 0 = normal cognition (NC); ≥0.5 = AD). …”
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