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401
Cochlear implantation and cognitive function in the older adult population: current state of the art and future perspectives
Published 2025-05-01“…Objectives: Hearing loss is associated with increased cognitive decline and incident dementia in older adults. Given the rapidly rising incidence of dementia, management of modifiable risk factors such as hearing loss, is essential to mitigate the impact on the individual and society in general. …”
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402
Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer’s Disease
Published 2015-01-01“…Recent research has provided evidence that insulin resistance and impaired insulin signalling may be a contributory factor to the progression of diabetes, dementia, and other neurological disorders. Alzheimer’s disease (AD) is the most common subtype of dementia. …”
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403
Why Are the Right and Left Hemisphere Conceptual Representations Different?
Published 2014-01-01“…The present survey develops a previous position paper, in which I suggested that the multimodal semantic impairment observed in advanced stages of semantic dementia is due to the joint disruption of pictorial and verbal representations, subtended by the right and left anterior temporal lobes, rather than to the loss of a unitary, amodal semantic system. …”
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404
Alzheimer’s Type Neuropathological Changes in a Patient with Depression and Anxiety: A Case Report and Literature Review of Neuropathological Correlates of Neuropsychiatric Symptom...
Published 2023-01-01“…Alzheimer’s disease (AD) is classified as a tauopathy and is the most common neuropathological correlate of dementia/cognitive impairment. AD is neuropathologically characterized by the presence of beta-amyloid immunoreactive senile plaques and tau positive neurofibrillary tangles. …”
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405
An Approach to Diagnostic Criteria for the Definition of Slight Cognitive Impairment
Published 2009-12-01“…For years the term slight cognitive impairment has been used in literature as a transitional stage between normal aging and a slight Alzheimer’s disease and in conversion studies it has been associated to quantitative and qualitative alterations that support that support the hypothesis that slight cognitive impairment constitutes an early stage of dementia in most of the patients. In this search the most updated diagnostic criteria on the topic have been reviewed looking for both a diagnostic consensus among the multiple and heterogeneous symptoms of this disorder and a clear, concise and uniform criterion that allow to reach a right definition and diagnosis of patients with slight cognitive impairment.…”
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406
The role of neurofilament light chain in the context of neurological disorders
Published 2020-12-01“…The purpose of this article is to review the literature on the role of NFL in the context of dementia, amyotrophic lateral sclerosis, HIV-associated neurocognitive disorders, multiple sclerosis, and other neurological diseases. …”
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407
Convergence of Synapses, Endosomes, and Prions in the Biology of Neurodegenerative Diseases
Published 2013-01-01Get full text
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408
Consensus on rapid screening for prodromal Alzheimer’s disease in China
Published 2024-02-01“…Alzheimer’s disease (AD) is a common cause of dementia, characterised by cerebral amyloid-β deposition, pathological tau and neurodegeneration. …”
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409
Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Published 2025-01-01“…Abstract Cognitive impairment and dementia have long been recognized as growing public health threats. …”
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410
A User-Centered Design Approach for a Screening App for People With Cognitive Impairment (digiDEM-SCREEN): Development and Usability Study
Published 2025-01-01“… Abstract BackgroundDementia is a widespread syndrome that currently affects more than 55 million people worldwide. …”
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411
Assessing the health implications of anticholinergic drugs in older people
Published 2025-01-01“…We propose practical guidelines for their use in clinical contexts such as dementia, schizophrenia, depression, anxiety, Parkinson’s disease, cardiovascular conditions, and urinary incontinence. …”
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412
Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link?
Published 2012-01-01“…However, cognitive decline often occurs in patients with advanced carotid stenosis without clinically evident stroke or TIA, so it is also suspected to be an independent risk factor for dementia. Neurosonological methods enable simple and noninvasive assessment of carotid stenosis in patients at risk of advanced atherosclerosis. …”
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413
Educational Needs of Health Care Providers Working in Long-Term Care Facilities with Regard to Pain Management
Published 2012-01-01“…BACKGROUND: The prevalence of chronic pain ranges from 40% to 80% in long-term care facilities (LTCF), with the highest proportion being found among older adults and residents with dementia. Unfortunately, pain in older adults is underdiagnosed, undertreated, inadequately treated or not treated at all. …”
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414
Long-Term Perseveration in Alzheimer’s Disease: A Case Report
Published 1991-01-01“…Presented here is a case of AD who, despite ultimate profound dementia with severe amnesia, showed retention of a perseverative response she developed during 26 encounters, over 4.5 years, with the Brown–Peterson distractor test. …”
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415
Mistreatment or not the best treatment to the elder. Reality and challenge
Published 2018-04-01“…Cuba is not exempted of this situation; the Cuban population ages and chronic non communicable diseases are a challenge to be concerned, mainly cancer, dementia, disability and prostration due to different causes which are the most frequent illnesses in elder people.…”
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416
From pixels to prognosis: radiomics and AI in Alzheimer’s disease management
Published 2025-01-01“…Alzheimer’s disease (AD), the leading cause of dementia, poses a growing global health challenge due to an aging population. …”
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417
Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions
Published 2018-01-01“…TAR DNA-binding protein-43 KDa (TDP-43) and fused in sarcoma (FUS) as the defining pathological hallmarks for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), coupled with ALS-FTD-causing mutations in both genes, indicate that their dysfunctions damage the motor system and cognition. …”
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418
Therapeutic Application of rTMS in Atypical Parkinsonian Disorders
Published 2021-01-01“…The terms atypical parkinsonian disorders (APDs) and Parkinson plus syndromes are mainly used to describe the four major entities of sporadic neuronal multisystem degeneration: progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), multiple system atrophy (MSA), and dementia with Lewy bodies (LBD). APDs are characterized by a variety of symptoms and a lack of disease modifying therapies; their treatment thus remains mainly symptomatic. …”
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419
Early-Onset Alzheimer’s Disease Masquerading as Catatonia
Published 2020-01-01“…This case is a cautionary reminder for clinicians that end stages of dementia can present similar to catatonia with mutism, lack of spontaneous movement, and refusal to eat. …”
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420
Cholecystoduodenal Fistula and Urosepsis in A Febrile Emergency Department Patient: A Case Report
Published 2025-01-01“…Case Report: We highlight the important POCUS findings of cholecystoduodenal fistula and staghorn calculus in a febrile, elderly patient with dementia. Conclusion: Early recognition of cholecystoduodenal fistula and staghorn calculus using POCUS can expedite appropriate antibiotic and interventional treatment for improved patient outcomes.…”
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