Dual Clinical Practice (DCP) policy to improve the retention of human resources for health in Rwanda: a mid-term review using a cross-sectional and retrospective study design by Kizito Kayumba, Corneille Ntihabose, Sabine Musange Furere, Bernard Ngabo, Piero Irakiza, Felix K. Rubuga, Nathalie Umutoni, Ina Rukundo Kalisa, Pascal Birindabagabo, Emile Rwamasirabo, Emmanuel Kayibanda, Patience Mukundirukuri, Gashaija Absolomon, Sumana Dhanani, Jeanine Condo

“…Abstract Background Despite the high demand for public services globally, ensuring the quality of services provided by public health facilities is challenging. …”
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Design and validation of a-SiC/SiN hybrid photonic platform for integrated quantum photonics by Naresh Sharma, Zizheng Li, Bruno Lopez-Rodriguez, Joey Vrugt, Stijn van der Waal, Luozhen Li, Roald van der Kolk, Philip J Poole, Dan Dalacu, Iman Esmaeil Zadeh

“…Quantum dots are particularly attractive due to their on-demand generation of high-purity single photons. Different photonic platforms are used to manipulate the states of the photons. …”
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Continuous theta-burst stimulation demonstrates language-network-specific causal effects on syntactic processing by Chenyang Gao, Junjie Wu, Yao Cheng, Yuming Ke, Xingfang Qu, Mingchuan Yang, Gesa Hartwigsen, Luyao Chen

“…These results shed light on the uniqueness and the specific causal role of the language network for the human language faculty, further supporting the causally separable view of the functional dissociation between the language network and the domain-general/multiple-demand network.…”
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Tackling antimicrobial resistance in Bangladesh: A scoping review of policy and practice in human, animal and environment sectors. by Roksana Hoque, Syed Masud Ahmed, Nahitun Naher, Mohammad Aminul Islam, Emily K Rousham, Bushra Zarin Islam, Shaikh Hassan

“…The development and transmission of AMR is deep-rooted in various supply and demand side factors. Implementation of existing policies and strategies remains a challenge due to poor awareness, inadequate resources and absence of national surveillance.…”
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Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome by Nadja Scherbakov, Marvin Szklarski, Jelka Hartwig, Franziska Sotzny, Sebastian Lorenz, Antje Meyer, Patricia Grabowski, Wolfram Doehner, Carmen Scheibenbogen

“…Patients with ED, in contrast to patients with normal endothelial function, reported more severe disease according to Bell score (31 ± 12 vs. 40 ± 16, P = 0.04), as well as more severe fatigue‐related symptoms (8.62 ± 0.87 vs. 7.75 ± 1.40, P = 0.04) including a higher demand for breaks [9.0 (interquartile range 7.0–10.0) vs. 7.5 (interquartile range 6.0–9.25), P = 0.04]. …”
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A Program for Master of Science in Environment and Natural Resources (MENR) by Kabale University

“…ENR programme is to produce mid-career level scientists to meet the immediate demand for environment and resource management specialists. …”
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Research Progress in and Planning Strategies for Multi-scale Measurement of the Efficiency of Urban Blue-Green Infrastructure in Carbon Sink Enhancement and Emission Reduction by Song LIU, Zhaocheng BAI, Dizi LIU, Peiyu SHEN

“…These strategies include: 1) At the site scale, for carbon sequestration and sink enhancement – carbon sink at the source, land balance, and ecological design; for emission reduction – symbiosis with buildings and integration into daily life. 2) At the community scale, for carbon sequestration – overall balance of revenue and expenditure, precise positioning, and proper interconnection of the carbon chain; for emission reduction – incorporation of cool islands and co-construction. 3) At the urban area scale, for carbon sequestration – enhancement of ecological space management and establishment of a carbon-safe pattern; for emission reduction – demand-based layout and organic dispersion. Finally, the research proposes five major research topics for the planning of UBGI’s carbon sink enhancement and emission reduction: How to construct unified measurement methods for UBGI’s efficiency in carbon sink enhancement and emission reduction across scales? …”
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Advancing poliovirus eradication: lessons learned from piloting direct molecular detection of polioviruses in high-risk and priority geographies by Paula L. Marcet, Brandon Short, Ashley Deas, Hong Sun, Chelsea Harrington, Shahzad Shaukat, Muhammad Masroor Alam, Marycelin Baba, Adedayo Faneye, Prossy Namuwulya, Lea Necitas Apostol, Tamer Elshaarawy, John Kofi Odoom, Peter Borus, Shelina Moonsamy, Yogolelo Riziki, Marie Claire Endegue Zanga, Mesfin Tefera, Anfumbom K. W. Kfutwah, Salmaan Sharif, Varja Grabovac, Cara C. Burns, Nancy Gerloff

“…DD-ITD implementation would entail building proficiency in advanced molecular laboratory techniques and data analysis, and increased demand for confirmatory sequencing.IMPORTANCESurveillance of acute flaccid paralysis (AFP) and sensitive poliovirus detection are key components of the WHO Global Polio Eradication Strategy. …”
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MOKSLO VERTYBINIO NEUTRALUMO PROBLEMA XX A. FILOSOFIJOJE (M. WEBERIS, ANALITINĖ MOKSLO FILOSOFIJA IR METAETIKA, KRITINĖ TEORIJA) by Zenonas Norkus

“…In this problem, three aspects are distinguished: logical one (represented by the dichotomy of descriptive and evaluative statements, and by "Hume's principle"); methodological one (demand to base acceptance and rejection of hypotheses on cognitive values only), and ethical one (prohibition to advocate and to promote noncognitive values on behalf of science). …”
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CD38 deficiency leads to a defective short-lived transcriptomic response to chronic graft-versus-host disease induction, involving purinergic signaling-related genes and distinct t... by Mercedes Zubiaur, Laura C. Terrón-Camero, Fernando Gordillo-González, Eduardo Andrés-León, Alicia Barroso-del Jesús, Luz María Canet-Antequera, María M. Pérez Sánchez-Cañete, África Martínez-Blanco, Marilú Domínguez-Pantoja, María Botia-Sánchez, Sonia Pérez-Cabrera, Nerea Bello-Iglesias, Antonio Alcina, Ana-Clara Abadía-Molina, Fuencisla Matesanz, Esther Zumaquero, Ramón Merino, Jaime Sancho

“…Last, we have shown an intense metabolic reprogramming toward oxidative phosphorylation in PECs and SPC from cGVHD WT mice, which may reflect an increased cellular demand for oxygen consumption, in contrast to PECs and SPC from cGVHD Cd38-/- mice, which showed a short-lived metabolic effect at the transcriptomic level. …”
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Metabolically activated and highly polyfunctional intratumoral VISTA+ regulatory B cells are associated with tumor recurrence in early-stage NSCLC by Domenico Lo Tartaro, Beatrice Aramini, Valentina Masciale, Nikolaos Paschalidis, Francesco Demetrio Lofaro, Anita Neroni, Rebecca Borella, Elena Santacroce, Alin Liviu Ciobanu, Anna Valeria Samarelli, Federica Boraldi, Daniela Quaglino, Alessandra Dubini, Michele Gaudio, Gloria Manzotti, Francesca Reggiani, Federica Torricelli, Alessia Ciarrocchi, Antonino Neri, Federica Bertolini, Massimo Dominici, Pier Luigi Filosso, Franco Stella, Lara Gibellini, Sara De Biasi, Andrea Cossarizza

“…VISTA+ Bregs displayed high metabolic demand and were able to produce different cytokines, including interleukin (IL)-10, transforming growth factor (TGF)-β, IL-6, tumor necrosis factor (TNF), and granulocyte–macrophage colony-stimulating factor (GM-CSF). …”
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Performance Analysis of Costs and Implementation Time Using Earned Value Method on the Distribution Pipe Network Expansion in Samarinda City by Dedy Sugi Hartawan, Wateno Oetomo, Risma Marleno

“…With the increasing need for clean water and the increasing population, PDAM Kota Samarinda must be able to meet demand with quality, quantity, continuity and accessible prices, as well as adequate water pressure. …”
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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…This was parallel to laboratory molecular investigations of in vitro GABAergic neurons derived from induced human pluripotent stem cells (hiPSCs) of SSADHD subjects and biochemical analyses performed on a versatile murine model that uses an inducible and reversible rescue strategy allowing on-demand and cell-specific gene therapy. Results The 62 SSADHD subjects [53% females, median (IQR) age of 9.6 (5.4–14.5) years] included in the study had a reported symptom onset at ∼ 6 months and were diagnosed at a median age of 4 years. …”
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Towards person-centred maternal and newborn care in Ethiopia: a mixed method study of satisfaction and experiences of care by Tigist Eshetu, Eshcolewyine Fekadu, Ahmed Abdella, Adiyam Mulushoa, Girmay Medhin, Merga Belina, Atalay Alem, Roxanne Keynejad, Tanya Robbins, Nadine Seward, Andrew Shennan, Louise M. Howard, Martin Prince, Jane Sandall, Charlotte Hanlon

“…Conclusions Systems strengthening interventions to support person-centred maternal care appear contextually relevant but need to increase women’s expectations of care and agency to demand change. Prioritization of person-centred care could improve women’s experience of maternal care and better address psychosocial needs.…”
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ADMINISTRATIVE PREREQUISITES FOR FINANCIAL MANAGEMENT AND MARKETING OF SMALL BUSINESSES AT THE REGIONAL LEVEL by Natalia Koval, Oksana Kubai, Natalia Germaniuk

“…The primary function of small businesses is the generation of employment opportunities, the swift adaptation to market fluctuations in supply and demand, and the replenishment of financial resources. …”
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Key experimental technologies and their development directions for the exploration and production of deep coalbed methane by Xia YAN, Fengyin XU, Xianyue XIONG, Feng WANG, Chunhu LI, Jiyuan ZHANG, Borui XU, Qianhui CHENG, Xiong HU, Xueguang ZHU, Wei LIANG, Pu YUAN, Yanqing FENG, Zhenji WEI

“…Analyses reveal that there is an urgent need to establish the standards and regulations for the operational procedures of these experimental technologies, as required by objective demand for the exploration and production of deep CBM. …”
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Editorial by Jörg Tremmel, Edward Page, Konrad Ott

“…These ‘permissions’ are scarce, that is: the demand is higher than the availability. Well-established distributive justice principles can be applied to the problem of allocating the absorptive capacity of the earth's atmosphere in a broadly analogous fashion to the problem of the just division of other scarce resources (food, water, shelter) between households. …”
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Genomic insights into the specialisation and selection of the Jinding duck by H. Chen, Y. Huang, J. Xue, K. luo, H. Tang, S. Zheng, Y. Xiong, Y. Wu, J. Li, R. Xuan, R. Xiong, Y. Gong, X. Fang, L. Wang, J. Miao, J. Zhou, H. Tan, Y. Wang, L. Wu, J. Ouyang, Y. Shen, X. Yan

“…Duck domestication plays a significant role in poultry production globally, meeting the growing demand for eggs and meat in various regions. Here, we focus on the Jinding Duck (JDD), a breed renowned for its prolific egg-laying traits. …”
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Selection of Superior Sugar Beet Genotypes using the Analysis of Quantitative and Qualitative Traits by Mahdi Hassani, Ali Saremirad, Hamed Mansouri

“…Given its fundamental role, enhancing traits crucial for sugar beet growth and yield is imperative to meet the escalating sugar demand forecasted for the future. Consequently, sugar beet breeding has long been a critical domain of research and development, focusing on enhancing yield, quality, and resistance to diseases of this essential commodity. …”
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Using Human-Centered Design to Bridge Zero-Dose Vaccine Gap: A Case Study of Ilala District in Tanzania by Simon Martin Nzilibili, Hellen Maziku, Awet Araya, Ruthbetha Kateule, Millenium Anthony Malamla, Suna Salum, Furaha Kyesi, Lotalis Gadau, Tumaini Menson Haonga, Florian Tinuga, Rashid Mfaume, Zaitun Hamza, Georgina Joachim, Alice Geofrey Mwiru, Alex Benson, Oscar Kapela, Ona Machangu, Norman Jonas, Ntuli Kapologwe

“…This study aimed to use the HCD approach to aid in identifying, prioritizing, and implementing community-centric interventions in Tanzania, particularly in the Ilala District of Dar es Salaam, to increase vaccine demand and close the zero-dose gap by at least 50%. …”
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