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  1. 5401

    Application of Concentration-Area fractal modeling and artificial neural network to identify Cu, Zn±Pb geochemical anomalies in Hashtjin area, NW of Iran by Ali Imamalipour, Hamed Ebrahimi, Amir reza Abdollahpur

    Published 2024-10-01
    “…Introduction Over the past few decades, the identification of geochemical anomalies has played an important role in mineral exploration (Coates et al., 2011; Lecun et al., 2015; Bergen et al., 2019) Various methods have been used to identify geochemical anomalies in the last few decades, including statistical analysis, geostatistical approaches (Nabavi, 1976), fractal modeling (Ziaii et al., 2009; Ziaii et al., 2012) and many other methods. …”
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  2. 5402

    Temporal and Spatial Analysis of Coastal Landscape Patterns Using the GEE Cloud Platform and Landsat Time Series by Chao Chen, Jintao Liang, Taohua Ren, Yi Wang, Zhisong Liu

    Published 2024-01-01
    “…The results indicate that, during nearly four decades, with the continuous expansion of the urban, the urbanization process has accelerated, and the construction land has expanded by 6.93 times. …”
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  3. 5403

    Regulation of Pear Fruit Quality: A Review Based on Chinese Pear Varieties by Ying Zhang, Yudou Cheng, Yuru Ma, Junfeng Guan, Hao Zhang

    Published 2024-12-01
    “…Internal quality traits refer to the nutritional value of fruits, which largely determine their flavor and palatability. Over the past decade, significant progress has been made in understanding the formation and regulatory mechanisms of fruit quality, with numerous key functional genes associated with quality traits being identified. …”
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  4. 5404

    Effects of Diverting Stoma Creation in Minimally Invasive Surgery for Rectal Cancer by Hirotaka Momose, Makoto Takahashi, Masaya Kawai, Kiichi Sugimoto, Hiromitsu Takahashi, Shunsuke Motegi, Kumpei Honjo, Yu Okazawa, Rina Takahashi, Shun Ishiyama, Yuichi Tomiki, Kazuhiro Sakamoto

    Published 2025-01-01
    “…DS creation has increased in the last few decades, without establishment of clear criteria for construction of a DS. …”
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  5. 5405

    Diversity and Abundance of the Species of Arboreal Mammals in a Tropical Rainforest in Southeast Mexico by J. Vladimir Rojas‐Sánchez, Rosamond Ione Coates, Víctor Sánchez‐Cordero, Mario C. Lavariega, José J. Flores‐Martínez

    Published 2025-01-01
    “…ABSTRACT Habitat loss threatens biodiversity worldwide being particularly detrimental in tropical rainforests where a cumulative deforestation expands for decades. Tropical rainforests harbor a rich mammal diversity with a wide range of species using different habitats, ranging from forest‐dwelling to arboreal species. …”
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  6. 5406

    Bioprinted hydrogels in bone regeneration: a bibliometric analysis by Huijie Zhang, Xiaoyu Li, Zhenyu Jia, Kun Jiao, Kun Jiao, Chen Liu, Chen Liu, Zixiang Deng, Yushu Bai, Xianzhao Wei, Xiaoyi Zhou

    Published 2025-02-01
    “…Our bibliometric-based visualization analysis revealed that the mechanical properties and osteogenic differentiation capacity of biomaterials have been a focal research topic over the past decade, while emerging research has also concentrated on the in vitro fabrication of stem cells for bone regeneration and osteogenic differentiation, particularly the precise application of in situ stem cell-loaded bioprinted organoids.ConclusionThis study provides an in-depth analysis of the research trajectory in the application of bioprinted hydrogels for bone regeneration. …”
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  7. 5407
  8. 5408

    Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production by Heather J Bax, Jitesh Chauhan, Alexandra J McCraw, Melanie Grandits, Chara Stavraka, Heike Lentfer, Tim Hillyer, Simon Carroll, Kim Vigor, Chris Selkirk, Mariangela Figini, Jack Cheeseman, Paulina A Urbanowicz, Richard A Gardner, Daniel I R Spencer, Nigel Westwood, Sarah Mellor, James Spicer, Debra H Josephs, Sophia N Karagiannis

    Published 2025-12-01
    “…Research-grade recombinant IgE antibodies have been generated and studied for several decades. The recent Phase 1 clinical trial of the first-in-class MOv18 IgE, however, necessitated the inaugural process development and scaled manufacture of a recombinant IgE to clinical quality standards. …”
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  9. 5409

    Differences in HIV infection trends in two regions of Cameroon with a longstanding HIV epidemic: insights from 2012 and 2022 by Yannick F. Ngoume, Urmes C. Teagho, Brice Eselacha, Oumarou H. Goni, Dell-Dylan Kenfack, Mérimé Tchakoute, Georges Nguefack-Tsague, Marcel Tongo, Marcel Tongo

    Published 2025-02-01
    “…Contrasting with these results, the HIV prevalence in the South during Period 1 was 5.5% and did not significantly change by Period 2 at 5.2% [PD: 0.3 (1.07;1.6); p = 0.67].ConclusionOur data suggest that HIV transmission in remote communities of the South administrative region of Cameroon has likely remained uncurbed over the past decade. As a result, this region should be prioritized in efforts to curb the spread of HIV and reduce its prevalence.…”
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  10. 5410

    Complexed hyaluronic acid-based nanoparticles in cancer therapy and diagnosis: Research trends by natural language processing by Abd Kakhar Umar, Patanachai K. Limpikirati, Bachtiar Rivai, Ilham Ardiansah, Sriwidodo Sriwidodo, Jittima Amie Luckanagul

    Published 2025-01-01
    “…We discovered that certain active substances, such as 5-aminolevulinic acid, adamantane, and protamine, have been on trend in terms of their usage over the past decade. Dextran, streptavidin, and catechol emerge as intriguing conjugates for HA, coupled with nanostar, quantum dots, and nanoprobe structures for optimal drug delivery and diagnostics. …”
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  11. 5411

    Opioid use and opioid overdose in the Netherlands – a 10 years retrospective study of naloxone administration in Dutch emergency departments by Bram Kok, Joris Holkenborg, Alba van der Have, Brigitte van de Kerkhof – van Bon, Joris Datema, Pieter Veenstra, Djoke Douma-den Hamer, Cornelis Kramers

    Published 2025-12-01
    “…Background: The number of opioid users in the Netherlands has doubled in the last two decades. To assess if the rise in use also means a rise in severe opioid intoxications, we studied the number of opioid intoxications necessitating naloxone administration in Dutch emergency departments during the last 10 years. …”
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  12. 5412

    An updated overview of Juvenile systemic sclerosis in a French cohort by Léa Jacquel, Rouba Bechara, Joëlle Terzic, Anne-Cécile Rameau, Emmanuel Chatelus, Linda Rossi-Semerano, Isabelle Kone-Paut, Ulrich Meinzer, Irène Lemelle, Charlotte Rebelle, Diego Urbina, Pascal Pillet, Pauline Choquet, Jad El Maamari, Ariane Zaloszyc, SOFREMIP

    Published 2025-02-01
    “…This study aimed to provide an overview of JSSc in France over the past decade. Methods Patients with disease onset before the age of 16 were included following a request for observations sent via email to member practitioners of the SOFREMIP (French pediatric Rheumatology society). …”
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  13. 5413
  14. 5414

    Weather resilience of the future Swiss electricity system with very high shares of variable renewable energy sources by Collin Killenberger, Nik Zielonka, Jan-Phillipp Sasse, Evelina Trutnevyte

    Published 2025-01-01
    “…To design weather-resilient electricity systems that rely on variable renewable energy sources (VRES), spatially-explicit modeling with several decades of historical weather data is necessary to avoid over-optimization to a single weather year. …”
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  15. 5415

    Defining polypharmacy in the elderly: a systematic review protocol by Seyede Salehe Mortazavi, Mohsen Shati, Seyed Kazem Malakouti, Abasali Keshtkar, Mohsen Bazargan, Shervin Assari

    Published 2016-03-01
    “…Today, polypharmacy, a common and important problem related to drug use, occurs subsequent to this multimorbidity in the elderly in all populations. In recent decades, several scientific investigations have studied polypharmacy and its correlates, using different approaches and definitions, and their results have been inconclusive. …”
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  16. 5416

    Global burden of colorectal cancer: epidemiology, risk factors by E. A. Medvedeva, G. G. Maryin, A. A. Leshchenko, M. V. Chernogorova, M. B. Dolgova, D. A. Nazarov, S. A. Ivanov

    Published 2022-12-01
    “…A few decades ago, colorectal cancer (CRC) was diagnosed much less frequently. …”
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  17. 5417

    Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy by Anna De Lucia, Lucia Mazzotti, Lucia Mazzotti, Anna Gaimari, Anna Gaimari, Matteo Zurlo, Roberta Maltoni, Claudio Cerchione, Sara Bravaccini, Angelo Delmonte, Lucio Crinò, Patricia Borges de Souza, Luigi Pasini, Fabio Nicolini, Fabrizio Bianchi, Manel Juan, Hugo Calderon, Chiara Magnoni, Chiara Magnoni, Luca Gazzola, Luca Gazzola, Paola Ulivi, Massimiliano Mazza

    Published 2025-02-01
    “…Over the past decades, significant progress has been made in the understanding of non-small cell lung cancer (NSCLC) biology and tumor progression mechanisms, resulting in the development of novel strategies for early detection and wide-ranging care approaches. …”
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  18. 5418

    Coculture with Eastern oysters is unlikely to reduce OsHV-1 impacts to farmed Pacific oysters: A modelling approach by Familusi Oluwatosin Adekunle, Gorka Bidegain, Tal Ben-Horin

    Published 2025-03-01
    “…In recent decades, the global expansion of Pacific oyster Magallana gigas aquaculture, driven by this species’ adaptability and rapid growth, has coincided with the emergence of novel and virulent microvariants (muvars) of Ostreid herpesvirus 1 (OsHV-1), causing significant industry losses. …”
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  19. 5419

    The youth mental health crisis: analysis and solutions by Patrick McGorry, Patrick McGorry, Hasini Gunasiri, Hasini Gunasiri, Cristina Mei, Cristina Mei, Simon Rice, Simon Rice, Caroline X. Gao, Caroline X. Gao

    Published 2025-01-01
    “…BackgroundSince the mid-20th century, mental illness has become a leading cause of health burden, particularly among adolescents and emerging adults, with most disorders emerging before the age of 25. Over the past two decades, mental ill health has surged to alarming levels, with evidence confirming that the increase is not just due to better awareness or diagnosis but reflects a genuine public health crisis.Study design/methodWe explore the evolving landscape of youth mental health and its contributing factors, including family dynamics, educational pressures, climate change, social media, and socio-economic challenges, potentially linked to neoliberal policies. …”
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  20. 5420

    Revolutionizing diagnosis of pulmonary Mycobacterium tuberculosis based on CT: a systematic review of imaging analysis through deep learning by Fei Zhang, Hui Han, Minglin Li, Tian Tian, Guilei Zhang, Zhenrong Yang, Feng Guo, Maomao Li, Yuting Wang, Jiahe Wang, Ying Liu

    Published 2025-01-01
    “…IntroductionThe mortality rate associated with Mycobacterium tuberculosis (MTB) has seen a significant rise in regions heavily affected by the disease over the past few decades. The traditional methods for diagnosing and differentiating tuberculosis (TB) remain thorny issues, particularly in areas with a high TB epidemic and inadequate resources. …”
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