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4141
Synthesis of Arginase Inhibitors: An Overview
Published 2025-01-01“…In mammals, there are two isoenzymes, ARG-1 and ARG-2; they are functionally similar, but their coding genes, tissue distribution, subcellular localization, and molecular regulation are distinct. In recent decades, the abnormal expression of ARG-1 or ARG-2 has been reported to be increasingly linked to a variety of diseases, including cardiovascular disease, inflammatory bowel disease, Alzheimer’s disease, and cancer. …”
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4142
An Update on Less Invasive and Endoscopic Techniques Mimicking the Effect of Bariatric Surgery
Published 2012-01-01“…These novel entities mimic several aspects of bariatric surgery either by gastric restriction (gastric balloons, gastric plication), by influencing gastric function (gastric botulinum injections, gastric pacing, and vagal nerve stimulation), or by partial exclusion of the small intestine (duodenal-jejunal sleeve). In the last decade, several novel less invasive techniques have been introduced and some have been abandoned again. …”
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4143
Evaluation of land ecological security and driving factors in the Lower Yellow River Flood Plain based on quality, structure and function
Published 2025-01-01“…The findings indicate a gradual improvement in LES over the past two decades, with spatial variations—higher in upstream and estuarine areas and lower in the middle. …”
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4144
Characterization of patients with sacrococcygeal pilonidal disease in the Coloproctology Service. Period 2020-2022
Published 2025-01-01“…<br /><strong>Results:</strong> sacrococcygeal pilonidal disease occurs more frequently in males, between the second and third decade of life in healthy patients. Prevail the surgical treatment. …”
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4145
Unfixed Bias Iterator: A New Iterative Format
Published 2025-01-01“…Solving PDEs numerically is usually done by first meshing the solution region with finite difference method (FDM) and then using iterative methods to obtain an approximation of the exact solution on these meshes, hence decades of research to design iterators with fast convergence properties. …”
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4146
Lifestyle Characteristics and Gastroesophageal Reflux Disease: A Population-Based Study in Albania
Published 2013-01-01“…We aimed to assess the prevalence and lifestyle correlates of gastroesophageal reflux disease (GERD) in the adult population of Albania, a Mediterranean country in Southeast Europe which has experienced major behavioral changes in the past two decades. Methods. A cross-sectional study, conducted in 2012, included a population-representative sample of 845 individuals (≥18 years) residing in Tirana (345 men, mean age: ; 500 women, mean age: ; response rate: 84.5%). …”
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4147
Perspectives for Sustainable Aviation Biofuels in Brazil
Published 2015-01-01“…The aviation industry has set ambitious goals to reduce carbon emissions in coming decades. The strategy involves the use of sustainable biofuels, aiming to achieve benefits from environmental, social, and economic perspectives. …”
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4148
Getting the best of carbon bang for mangrove restoration buck
Published 2025-02-01“…The estimated mangrove ESV in 2019 amounts to $894 billion yr−1, mainly provided by regulating and provisioning services (57.4% and 19.7%). Over the next two decades, we project that the restoration of mangroves would necessitate an investment of $40.0–52.1 billion, yielding net gains in ESV of $231–725 billion. …”
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4149
Utilization of Edible-Insects as Protein Substitute in Food and Effects of Processing on Their Nutrient Contents and Protein Functionalities
Published 2022-12-01“…Efforts need to be strengthened to secure global acceptance of insect protein since the conventional sources are not reliable and cannot satisfy the world population in decades to come.</p>…”
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4150
Chemical constituents, biological functions and pharmacological effects for comprehensive utilization of Eucommia ulmoides Oliver
Published 2019-06-01“…Traditionally, the comprehensive utilization rate of E. ulmoides Oliv. is still very low, only bark has been used as medicine and other parts of Eucommia ulmoides Oliv. cannot be fully utilized, even the leaves have been well utilized in food products in Japan in the past decades. In order to improve the comprehensive utilization efficiency of E. ulmoides Oliv., in this review, we summarized the varieties and contents of main active compounds, biological functions and pharmacological effects in different parts of E. ulmoides Oliv. …”
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4151
Detection of Foodborne Pathogens Through Volatile Organic Compounds Sensing via Metal Oxide Gas Sensors
Published 2025-01-01“…Abstract Foodborne pathogens are a crucial diagnostic target for the food, beverage, and healthcare sectors due to their ubiquity and the potential damage they may do to the public's well‐being, food safety, and the economy. Over the past few decades, there has been an increased focus on developing highly precise and trusted biosensors in an effort to eliminate the discrepancy between reporting demands and currently used traditional detection approaches. …”
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4152
Can we do more than case studies? A scoping review about qualitative research in sport management in the Brazilian context
Published 2025-01-01“… Introduction: In the past two decades, sport management research in Brazil has progressed, but there are some issues hindering this development. …”
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4153
Inflammation and Inflammasomes: Pros and Cons in Tumorigenesis
Published 2020-01-01“…Over the past decade, it has been well established that tumorigenesis is affected by chronic inflammation. …”
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4154
Examining the landscape transformation and temperature dynamics in Pakistan
Published 2025-01-01“…This research is being conducted in Pakistan to identify the vegetation cover, water bodies, impervious surfaces, and land surface temperature using decadal remote sensing data with four intervals during 1993–2023 in the Mardan division, Khyber Pakhtunkhwa. …”
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4155
A simple model of HIV epidemic in Italy: The role of the antiretroviral treatment
Published 2018-01-01“…The values of the model parameters not reported in the literature are assessed by fitting available epidemiological data over the decade $2003 \div 2012$. Predictions until year 2025 are computed, enlightening the impact on the public health of the early initiation of the antiretroviral therapy. …”
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4156
Peptide-Based Vaccinology: Experimental and Computational Approaches to Target Hypervariable Viruses through the Fine Characterization of Protective Epitopes Recognized by Monoclon...
Published 2013-01-01“…Experimental approaches aiming to characterize protective mAb epitopes or to identify T-cell-activating peptides are often burdened by technical limitations and can require long time to be correctly addressed. Thus, in the last decade many epitope predictive algorithms have been developed. …”
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4157
Prevention of LPS-Induced Acute Lung Injury in Mice by Progranulin
Published 2012-01-01“…The acute respiratory distress syndrome (ARDS), a clinical complication of severe acute lung injury (ALI) in humans, is a leading cause of morbidity and mortality in critically ill patients. Despite decades of research, few therapeutic strategies for clinical ARDS have emerged. …”
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4158
Failure of Colorectal Anastomosis: Risk Factors, Prevention, Diagnosis, Therapeutic Tactics
Published 2019-05-01“…Key findings. Over the last decade, there has been an increasing trend towards sphincter-preserving operations in modern colorectal surgery. …”
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4159
Identifying enablers for a circular healthcare supply chain: An integrated fuzzy DEMATEL-MMDE approach with hesitant information
Published 2025-02-01“…Over the past decade, the healthcare industries have been facing the issue of resource scarcity due to socio-political wars, the COVID-19 pandemic, the luxury lifestyles of people, and the prevalence of single-use medical devices. …”
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4160
A systematic review of the neglected parasite cyclospora cayetanensis in türkiye from 2004 to 2023
Published 2024-12-01“…This study aimed to determine the prevalence of C. cayetanensis in Türkiye over the last two decades. A comprehensive literature search was conducted in databases Google Scholar, PubMed, Scopus, Mendeley, Web of Science, YOKtez, TR Dizin, and Türk MEDLINE Index for relevant English and Turkish publications from 2004 to 2023. …”
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