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3761
Integrating Handcrafted Features with Machine Learning for Hate Speech Detection in Albanian Social Media
Published 2024-12-01“…Online social media has seen a significant increase in usage over the last decade, enabling people to communicate more easily. …”
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3762
Molecular Insights in the Anticancer Activity of Natural Tocotrienols: Targeting Mitochondrial Metabolism and Cellular Redox Homeostasis
Published 2025-01-01“…The role of mitochondria as the electric engine of cells is well established. Over the past two decades, accumulating evidence has pointed out that, despite the presence of a highly active glycolytic pathway (Warburg effect), a functional and even upregulated mitochondrial respiration occurs in cancer cells to meet the need of high energy and the biosynthetic demand to sustain their anabolic growth. …”
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3763
Distribution and Risk Factors of Water-Related Accidents for General Aviation Aircraft
Published 2021-01-01“…In the past two decades, dozens to more than a hundred people have died each year in water-related accidents, most of which general aviation has accounted for. …”
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3764
The impact of aging on neutrophil functions and the contribution to periodontitis
Published 2025-01-01“…Abstract The increasing aging population and aging-associated diseases have become a global issue for decades. People over 65 show an increased prevalence and greater severity of periodontitis, which poses threats to overall health. …”
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3765
Calcium/calmodulin-dependent protein kinase II α and β differentially regulate mammalian sleep
Published 2025-01-01“…Abstract While sleep is important, our understanding of its molecular mechanisms is limited. Over the last two decades, protein kinases including Ca2+/calmodulin-dependent protein kinase II (CaMKII) α and β have been implicated in sleep regulation. …”
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3766
Cellular Reprogramming, Genome Editing, and Alternative CRISPR Cas9 Technologies for Precise Gene Therapy of Duchenne Muscular Dystrophy
Published 2017-01-01“…In the past decade, the development of two innovative technologies, namely, induced pluripotent stem cells (iPSCs) and the CRISPR Cas9 system, has enabled researchers to model diseases derived from patient cells and precisely edit DNA sequences of interest, respectively. …”
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3767
Decision models enhancing environmental flow sustainability: A strategic approach to water resource management
Published 2024-10-01“…The urgent need to preserve river ecosystems by sustaining environmental flow (EF) in the realm of environmental management has been highlighted by the drastic changes to river ecosystems and upstream flow dynamics brought about by careless river exploitation in the last few decades. To optimize EF in river basin management, we present an integrated modeling approach. …”
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3768
Pulmonary Hypertension in Pregnancy: Critical Care Management
Published 2012-01-01“…Pulmonary hypertension in pregnant patients carries a high mortality rates between 30–56%. In the past decade, new treatments for pulmonary hypertension have emerged. …”
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3769
Technical Aspects of Laparoscopic Distal Pancreatectomy for Benign and Malignant Disease: Review of the Literature
Published 2015-01-01“…Despite the obvious advantages of laparoscopic surgery, postoperative morbidity remains relatively high, mainly because of the high incidence of pancreatic fistula. For decades, surgeons have tried to prevent these fistulas but to date no strategy has been confirmed to be effective in 2 consecutive randomized studies. …”
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3770
Ultra‐Low Threshold Resonance Switching by Terahertz Field Enhancement‐Induced Nanobridge
Published 2025-01-01“…Abstract Ongoing efforts spanning decades aim to enhance the efficiency of optical devices, highlighting the need for a pioneering approach in the development of next‐generation components over a broad range of electromagnetic wave spectra. …”
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3771
Expert consensus on pulpotomy in the management of mature permanent teeth with pulpitis
Published 2025-01-01“…Abstract Pulpotomy, which belongs to vital pulp therapy, has become a strategy for managing pulpitis in recent decades. This minimally invasive treatment reflects the recognition of preserving healthy dental pulp and optimizing long-term patient-centered outcomes. …”
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3772
Small Molecule, Big Prospects: MicroRNA in Pregnancy and Its Complications
Published 2017-01-01“…In contrast, the study of microRNA in pregnancy and its associated complications, such as preeclampsia (PE), fetal growth restriction (FGR), and preterm labor, is a young field. Over the last decade, the knowledge of pregnancy-related microRNAs has increased and the molecular mechanisms by which microRNAs regulate pregnancy or its associated complications are emerging. …”
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3773
Investigating the effect of urban governance on urban resilience (Case study: Tehran)
Published 2022-12-01“…In recent decades, the issue of resilience has become a specialized and public issue in society. …”
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3774
In Vitro Uptake of Hydroxyapatite Nanoparticles and Their Effect on Osteogenic Differentiation of Human Mesenchymal Stem Cells
Published 2018-01-01“…There have been many applications in biomedical fields based on hydroxyapatite nanoparticles (HA NPs) over the past decades. However, the biocompatibility of HANPs is affected by exposure dose, particle size, and the way of contact with cells. …”
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3775
Steppe Eagles in Bokey-Orda Nature Reserve and Ashiozek Sanctuary (Western Kazakhstan Region) in 2022–2023
Published 2023-10-01“…The Steppe Eagle (Aquila nipalensis) is a typical and representative inhabitant of the steppe, a key predator in steppe ecosystems, and until recently the most common and abundant of Kazakhstan’s large raptors. In the last two decades, its abundance and range here have been greatly reduced. …”
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3776
Role of proteases in oral carcinogenesis: Insights into the cancer degradome and therapeutic implications
Published 2024-06-01“…Despite therapeutic advancements, OSCC's morbidity and mortality rates have seen little improvement over decades, necessitating deeper molecular understanding for effective treatment strategies. …”
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3777
Human Bone Marrow Mesenchymal Stromal Cells Promote Bone Regeneration in a Xenogeneic Rabbit Model: A Preclinical Study
Published 2018-01-01“…Significant research efforts have been undertaken during the last decades to treat musculoskeletal disorders and improve patient’s mobility and quality of life. …”
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3778
Sesquiterpene Lactones as Promising Anti-Glioblastoma Drug Candidates Exerting Complex Effects on Glioblastoma Cell Viability and Proneural–Mesenchymal Transition
Published 2025-01-01“…The current review aims to systematize the knowledge on the anti-glioblastoma potential of STLs accumulated over the last decade and to identify key processes in glioblastoma cells that are most susceptible to the action of STLs. …”
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3779
SPECT and PET Imaging of Meningiomas
Published 2012-01-01“…They are usually diagnosed after the third decade of life and they are more frequent in women than in men. …”
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3780
Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine
Published 2012-01-01“…Much progress has been made since the discovery of AM and AF cells with stem cell characteristics nearly a decade ago, but there remain a number of problematic issues stemming from the inherent heterogeneity of these cells as well as inconsistencies in isolation and culturing methods which must be addressed to advance the field towards the development of cell-based therapies. …”
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