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  1. 3761

    Integrating Handcrafted Features with Machine Learning for Hate Speech Detection in Albanian Social Media by Fetahi Endrit, Hamiti Mentor, Susuri Arsim, Zenuni Xhemal, Ajdari Jaumin

    Published 2024-12-01
    “…Online social media has seen a significant increase in usage over the last decade, enabling people to communicate more easily. …”
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    Article
  2. 3762

    Molecular Insights in the Anticancer Activity of Natural Tocotrienols: Targeting Mitochondrial Metabolism and Cellular Redox Homeostasis by Raffaella Chiaramonte, Giulia Sauro, Domenica Giannandrea, Patrizia Limonta, Lavinia Casati

    Published 2025-01-01
    “…The role of mitochondria as the electric engine of cells is well established. Over the past two decades, accumulating evidence has pointed out that, despite the presence of a highly active glycolytic pathway (Warburg effect), a functional and even upregulated mitochondrial respiration occurs in cancer cells to meet the need of high energy and the biosynthetic demand to sustain their anabolic growth. …”
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  3. 3763

    Distribution and Risk Factors of Water-Related Accidents for General Aviation Aircraft by Ruiliang Yang, LibinYang, Lina Zhao, Donghan Geng

    Published 2021-01-01
    “…In the past two decades, dozens to more than a hundred people have died each year in water-related accidents, most of which general aviation has accounted for. …”
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    Article
  4. 3764

    The impact of aging on neutrophil functions and the contribution to periodontitis by Zi Wang, Anish Saxena, Wenbo Yan, Silvia M. Uriarte, Rafael Siqueira, Xin Li

    Published 2025-01-01
    “…Abstract The increasing aging population and aging-associated diseases have become a global issue for decades. People over 65 show an increased prevalence and greater severity of periodontitis, which poses threats to overall health. …”
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    Article
  5. 3765

    Calcium/calmodulin-dependent protein kinase II α and β differentially regulate mammalian sleep by Weiwen Yang, Jingyi Shi, Chenggang Li, Jingqun Yang, Jianjun Yu, Juan Huang, Yi Rao

    Published 2025-01-01
    “…Abstract While sleep is important, our understanding of its molecular mechanisms is limited. Over the last two decades, protein kinases including Ca2+/calmodulin-dependent protein kinase II (CaMKII) α and β have been implicated in sleep regulation. …”
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  6. 3766

    Cellular Reprogramming, Genome Editing, and Alternative CRISPR Cas9 Technologies for Precise Gene Therapy of Duchenne Muscular Dystrophy by Peter Gee, Huaigeng Xu, Akitsu Hotta

    Published 2017-01-01
    “…In the past decade, the development of two innovative technologies, namely, induced pluripotent stem cells (iPSCs) and the CRISPR Cas9 system, has enabled researchers to model diseases derived from patient cells and precisely edit DNA sequences of interest, respectively. …”
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  7. 3767

    Decision models enhancing environmental flow sustainability: A strategic approach to water resource management by Seiran Haghgoo, Jamil Amanollahi, Barzan Bahrami Kamangar, Shahryar Sorooshian

    Published 2024-10-01
    “…The urgent need to preserve river ecosystems by sustaining environmental flow (EF) in the realm of environmental management has been highlighted by the drastic changes to river ecosystems and upstream flow dynamics brought about by careless river exploitation in the last few decades. To optimize EF in river basin management, we present an integrated modeling approach. …”
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  8. 3768

    Pulmonary Hypertension in Pregnancy: Critical Care Management by Adel M. Bassily-Marcus, Carol Yuan, John Oropello, Anthony Manasia, Roopa Kohli-Seth, Ernest Benjamin

    Published 2012-01-01
    “…Pulmonary hypertension in pregnant patients carries a high mortality rates between 30–56%. In the past decade, new treatments for pulmonary hypertension have emerged. …”
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  9. 3769

    Technical Aspects of Laparoscopic Distal Pancreatectomy for Benign and Malignant Disease: Review of the Literature by T. de Rooij, R. Sitarz, O. R. Busch, M. G. Besselink, M. Abu Hilal

    Published 2015-01-01
    “…Despite the obvious advantages of laparoscopic surgery, postoperative morbidity remains relatively high, mainly because of the high incidence of pancreatic fistula. For decades, surgeons have tried to prevent these fistulas but to date no strategy has been confirmed to be effective in 2 consecutive randomized studies. …”
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    Article
  10. 3770

    Ultra‐Low Threshold Resonance Switching by Terahertz Field Enhancement‐Induced Nanobridge by Sang‐Hun Lee, Moohyuk Kim, Yeeun Roh, Myung‐Ki Kim, Minah Seo

    Published 2025-01-01
    “…Abstract Ongoing efforts spanning decades aim to enhance the efficiency of optical devices, highlighting the need for a pioneering approach in the development of next‐generation components over a broad range of electromagnetic wave spectra. …”
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  11. 3771

    Expert consensus on pulpotomy in the management of mature permanent teeth with pulpitis by Lu Zhang, Chen Lin, Zhuo Chen, Lin Yue, Qing Yu, Benxiang Hou, Junqi Ling, Jingping Liang, Xi Wei, Wenxia Chen, Lihong Qiu, Jiyao Li, Yumei Niu, Zhengmei Lin, Lei Cheng, Wenxi He, Xiaoyan Wang, Dingming Huang, Zhengwei Huang, Weidong Niu, Qi Zhang, Chen Zhang, Deqin Yang, Jinhua Yu, Jin Zhao, Yihuai Pan, Jingzhi Ma, Shuli Deng, Xiaoli Xie, Xiuping Meng, Jian Yang, Xuedong Zhou, Zhi Chen

    Published 2025-01-01
    “…Abstract Pulpotomy, which belongs to vital pulp therapy, has become a strategy for managing pulpitis in recent decades. This minimally invasive treatment reflects the recognition of preserving healthy dental pulp and optimizing long-term patient-centered outcomes. …”
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  12. 3772

    Small Molecule, Big Prospects: MicroRNA in Pregnancy and Its Complications by Meng Cai, Gopi K. Kolluru, Asif Ahmed

    Published 2017-01-01
    “…In contrast, the study of microRNA in pregnancy and its associated complications, such as preeclampsia (PE), fetal growth restriction (FGR), and preterm labor, is a young field. Over the last decade, the knowledge of pregnancy-related microRNAs has increased and the molecular mechanisms by which microRNAs regulate pregnancy or its associated complications are emerging. …”
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    Article
  13. 3773

    Investigating the effect of urban governance on urban resilience (Case study: Tehran) by Gholam Reza soroushan, Abdallah hendiani, parvane zivyar pardei, Ali tavakolan

    Published 2022-12-01
    “…In recent decades, the issue of resilience has become a specialized and public issue in society. …”
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  14. 3774

    In Vitro Uptake of Hydroxyapatite Nanoparticles and Their Effect on Osteogenic Differentiation of Human Mesenchymal Stem Cells by Xing Yang, Yuanyuan Li, Xujie Liu, Ranran Zhang, Qingling Feng

    Published 2018-01-01
    “…There have been many applications in biomedical fields based on hydroxyapatite nanoparticles (HA NPs) over the past decades. However, the biocompatibility of HANPs is affected by exposure dose, particle size, and the way of contact with cells. …”
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    Article
  15. 3775

    Steppe Eagles in Bokey-Orda Nature Reserve and Ashiozek Sanctuary (Western Kazakhstan Region) in 2022–2023 by Ilya E. Smelyansky, Andrei A. Tomilenko, Anna N. Barashkova, Roman N. Aleksandrovich, Beibars Kitibaev, Alyona Koshkina

    Published 2023-10-01
    “…The Steppe Eagle (Aquila nipalensis) is a typical and representative inhabitant of the steppe, a key predator in steppe ecosystems, and until recently the most common and abundant of Kazakhstan’s large raptors. In the last two decades, its abundance and range here have been greatly reduced. …”
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  16. 3776

    Role of proteases in oral carcinogenesis: Insights into the cancer degradome and therapeutic implications by Gargi S. Sarode, Sachin C. Sarode, Urmi Ghone, Rahul Anand

    Published 2024-06-01
    “…Despite therapeutic advancements, OSCC's morbidity and mortality rates have seen little improvement over decades, necessitating deeper molecular understanding for effective treatment strategies. …”
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    Article
  17. 3777

    Human Bone Marrow Mesenchymal Stromal Cells Promote Bone Regeneration in a Xenogeneic Rabbit Model: A Preclinical Study by Juan Francisco Blanco, Jesús García-Briñon, Lorena Benito-Garzón, David Pescador, Sandra Muntión, Fermín Sánchez-Guijo

    Published 2018-01-01
    “…Significant research efforts have been undertaken during the last decades to treat musculoskeletal disorders and improve patient’s mobility and quality of life. …”
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    Article
  18. 3778

    Sesquiterpene Lactones as Promising Anti-Glioblastoma Drug Candidates Exerting Complex Effects on Glioblastoma Cell Viability and Proneural–Mesenchymal Transition by Andrey V. Markov, Arseny D. Moralev, Kirill V. Odarenko

    Published 2025-01-01
    “…The current review aims to systematize the knowledge on the anti-glioblastoma potential of STLs accumulated over the last decade and to identify key processes in glioblastoma cells that are most susceptible to the action of STLs. …”
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  19. 3779

    SPECT and PET Imaging of Meningiomas by Varvara Valotassiou, Anastasia Leondi, George Angelidis, Dimitrios Psimadas, Panagiotis Georgoulias

    Published 2012-01-01
    “…They are usually diagnosed after the third decade of life and they are more frequent in women than in men. …”
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  20. 3780

    Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine by Kerry Rennie, Andrée Gruslin, Markus Hengstschläger, Duanqing Pei, Jinglei Cai, Toshio Nikaido, Mahmud Bani-Yaghoub

    Published 2012-01-01
    “…Much progress has been made since the discovery of AM and AF cells with stem cell characteristics nearly a decade ago, but there remain a number of problematic issues stemming from the inherent heterogeneity of these cells as well as inconsistencies in isolation and culturing methods which must be addressed to advance the field towards the development of cell-based therapies. …”
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    Article