Integration of bulk and single-cell RNA-seq reveals prognostic gene signatures in patients with bladder cancer treated with immune checkpoint inhibitors by Mina Cho, Hyun Chang, Ju Han Kim

“…However, as the benefits of programmed death-1/ programmed death-ligand-1 blockade immunotherapy do not extend to all patients with BC, biomarkers are required to improve prognostic stratification. …”
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Exploring the protective role of caffeine against Taraxacum-Induced ribotoxic stress mediated through autophagy and mitochondrial depolarization by Chien-Jung Lin, Shu-Ting Liu, Zih-Syuan Wu, Shih-Ming Huang, Teng-Wei Chen

“…However, caffeine could only change the populations of necrotic and apoptotic cells but not T. formosanum-induced cell death. By providing detailed information on Taraxacum-induced rRNA cleavage and N-truncated histone H3’s mechanisms of gene regulation, we hope to understand their respective cellular death and survival stresses.…”
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Survivorship and Severe Complications Are Worse for Octogenarians and Elderly Patients with Pelvis Fractures as Compared to Adults: Data from the National Trauma Data Bank by Amir Matityahu, Joshua Elson, Saam Morshed, Meir Marmor

“…Hypovolemic shock had 7.65-fold increased odds of death and 6.31-fold higher odds of severe complications. …”
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The influence of different forms of apple products on all-cause mortality in patients with hypertension by Chuang Sun, Yingying Chen, Yue Guan, Yiming Zeng, Jie Li, Liang Chen

“…However, the consumption of apple juice (HR = 1.02, 95% CI: 0.67–1.56, p = 0.930) and sauce (HR = 1.28, 95% CI: 0.59–2.74, p = 0.531) tended to increase the risk of death in patients with hypertension, although this study did not obtain a statistically result.ConclusionModerate consumption of whole apples is associated with a reduced risk of all-cause death in patients with hypertension, whereas apple juice and sauce may increase the risk of death.…”
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Sarcopenia, myosteatosis and inflammation are independent prognostic factors of SARS-CoV-2 pneumonia patients admitted to the ICU by Romain Chauvot de Beauchene, Bertrand Souweine, Benjamin Bonnet, Bertrand Evrard, Yves Boirie, Lucie Cassagnes, Claire Dupuis

“…Abstract The aims of our study were to assess the correlations between sarcopenia and myosteatosis assessed by CT-scan at T4 and/or L3 levels and inflammation in critically ill COVID patients on ICU admission, and their respective prognostic value on day 90 death (D90-death). It is a retrospective monocentric study. …”
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Posthumous coins of the Legnica-Brzeg Piasts by Robert Pieńkovski

“… An interesting product of the Silesian mints in the early modern period are coins commemorating the death of successive members of the Legnica-Brzeg Piast dynasty. …”
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Does stapled colorectal anastomosis in anterior resection always guarantee restoration of intestinal continuity? by P. V. Tsarkov, A. Yu. Kravchenko, I. A. Tulina, P. B. Tsugulya

“…When sphincter-sparing operations are performed for all stages of rectal cancer the most essential risk factors of non-closure of stoma were progression of disease and chemotherapy treatment and patient death related to it, and patient’s death.…”
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Uncoded chronic kidney disease prevalence in secondary care: a retrospective audit with population health implications by Samantha Dolan, Ajitesh Anand, Philip A. Kalra, Stuart Stewart

“…Age, sex, indices of multiple deprivation, and AKI were significant predictors of death during admission. Advanced CKD was a significant predictor of AKI during admission. …”
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Institutional Incidence of Severe tPA-Induced Angioedema in Ischemic Cerebral Vascular Accidents by Matthew Sczepanski, Paul Bozyk

“…The survival probability was higher in the angioedema group and mean time to death was twenty-two days in the angioedema group and twenty-one days in the nonangioedema group. …”
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Risk factors for non-benefit of implantable cardioverter defibrillator therapy by Fabienne Kreimer, Marie Lewenhardt, Ibrahim El-Battrawy, Arash Haghikia, Michael Gotzmann

“…Abstract Studies have demonstrated overall prognostic benefits of ICD implantation in patients at increased risk of sudden cardiac death. However, results are inconsistent in certain subgroups. …”
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Socioeconomic Assessment and Impact of Social Security on Outcome in Patients Admitted with Suspected Coronary Chest Pain in the City of Salta, Argentina by Ricardo A. León de la Fuente, Patrycja A. Naesgaard, Stein Tore Nilsen, Leik Woie, Torbjoern Aarsland, Harry Staines, Dennis W. T. Nilsen

“…We assessed total mortality, cardiac death, and sudden cardiac death (SCD) in relation to socioeconomic class and social security in 982 patients consecutively admitted with suspected coronary chest pain, living in the city of Salta, northern Argentina. …”
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Burden of mortality related to pregnancy, childbirth and the puerperium. Cuba 2005-2018 by Delia María Galvez Medina, Lisbeth Fernández González, Armando Humberto Seuc Jo, José Luis Peñalvo García, Miguel Ángel Martínez Morales, Vivian Herrera Gómez

“…<p><strong>Background</strong>: maternal death represents one of the most notable events in the conflicts of sexual and reproductive health in the world. …”
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Lithium Improves Survival of PC12 Pheochromocytoma Cells in High-Density Cultures and after Exposure to Toxic Compounds by Cinzia Fabrizi, Stefania De Vito, Francesca Somma, Elena Pompili, Angela Catizone, Stefano Leone, Paola Lenzi, Francesco Fornai, Lorenzo Fumagalli

“…The correlation between autophagy and cell death is still a matter of debate especially in transformed cells. …”
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Impact of geriatric nutritional risk index and diabetes mellitus on prognosis in ischaemic heart failure with reduced ejection fraction by Zhiyong Shi, Mingkai Yun, Haiyan Liu, Sijin Li, Xiaoli Zhang

“…The DM/low GNRI (L-GNRI) group had the highest risk of all-cause death (HRadj: 3.253, 95% CI 1.643–6.474, P < 0.001) and cardiac death (HRadj: 3.411, 95% CI 1.606–7.243, P < 0.001) compared to the non-DM/high GNRI group. …”
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Autoimmune Hepatitis with Acute Presentation: Clinical, Biochemical, and Histological Features of 126 Patients by Álvaro Urzúa, Carolina Pizarro, Abraham Gajardo, Rafael Poniachik, Claudia Pavez, Máximo Cattaneo, Javier Brahm, Laura Carreño, Jaime Poniachik

“…We clinically characterized patients with AAIH, the prevalence of a combined adverse outcome (death or liver transplantation (LT)), and its risk factors. …”
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Dying to be famous: retrospective cohort study of rock and pop star mortality and its association with adverse childhood experiences by Mark A Bellis, Karen Hughes, Olivia Sharples, Tom Hennell, Katherine A Hardcastle

“…We examine relationships between fame and premature mortality and test how such relationships vary with type of performer (eg, solo or band member) and nationality and whether cause of death is linked with prefame (adverse childhood) experiences.Design A retrospective cohort analysis based on biographical data. …”
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Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins Supplementation by Hossna M. Ismail, Abdel-Aziz S. Shatat

“… Colorectal cancer (CRC) is the leading cause of death from gastrointestinal cancer, the second largest cause of cancer-related death worldwide, and the third most common cancer in both men and women. …”
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Exposure to Glycolytic Carbon Sources Reveals a Novel Layer of Regulation for the MalT Regulon by Sylvia A. Reimann, Alan J. Wolfe

“…The use of synthetic lethality, a genetic phenomenon in which the combination of two nonlethal mutations causes cell death, facilitates identification and study of such circuitry. …”
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The Intergenerational Transfer of Infant Mortality in Northern Norway during the 19th and Early 20th Centuries by Hilde Leikny Sommerseth

“…The risk of an infant death occurring among the children of daughters from such ‘high risk’ families was at least 30 per cent higher than that amongst infants born to the daughters of mothers who had experienced zero infant deaths.…”
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