The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum by Alexander A. Morano, Wei Xu, Francesca M. Navarro, Neeta Shadija, Jeffrey D. Dvorin, Hangjun Ke

“…PfDyn2’s singular role in mediating both apicoplast and mitochondrial fission has not been observed in other organisms possessing two endosymbiotic organelles, including other Apicomplexans, thus reflecting a unique, potentially exploitable method of organellar division in P. falciparum.IMPORTANCEPlasmodium falciparum remains a significant global pathogen, causing over 200 million infections and over 600,000 deaths per year. One significant obstacle to the control of malaria is increasing resistance to first-line artemisinin-based antimalarials. …”
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The management and clinical outcome of paracetamol poisoning in South African adults: A single-centre retrospective review by C Kotze, J Swanepoel, E C Kruger, E Decloedt

“…A significant proportion of deaths occurred in those with accidental overdose compared with those with intentional overdosing (57% v. 7.2%; p=0.004). …”
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Prevalence of lumpy skin disease and associated risk factors in beef cattle in Rembang Regency, Central Java, Indonesia by Yayan Taufiq Hidayat, Roza Azizah Primatika, Yatri Drastini

“…Rembang Regency, located in Central Java, Indonesia, has suffered over 3800 cases of LSD and 75 deaths since early 2023. This region holds the 4th number of most populous beef cattle producers in Central Java. …”
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Effect of “Helping Babies Breathe” Training on Ethiopian Undergraduate Midwifery Students’ Knowledge and Skills in Neonatal Resuscitation at Public Universities: A Non-Randomized Q... by Endalew Gemechu Sendo, Girum Sebsibe Teshome, Wegnesh Kelbessa Jirata, Lemi Abebe Gebrewold, Rahel Endalew Gemechu

“…Helping Babies Breathe (HBB) is a global initiative launched by the American Academy of Pediatrics (AAP) in 2010, aimed at reducing neonatal mortality by addressing birth asphyxia, a leading cause of newborn deaths worldwide. The HBB training program trains providers in effectively resuscitating infants in developing countries, including Ethiopia. …”
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Incidence, trends and patterns of female breast, cervical, colorectal and prostate cancers in Antigua and Barbuda, 2017–2021: a retrospective study by Andre A. N. Bovell, Thendo Ramaliba, Sekeena O. Goodwin, Joycelyn C. Phillip, Jabulani Ncayiyana, Themba G. Ginindza

“…Abstract Background Globally, estimates of cancer cases and deaths have increased since 2018, particularly in Latin America and Caribbean countries. …”
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Modeling control strategies for concurrent epidemics of seasonal and pandemic H1N1 influenza by Olivia Prosper, Omar Saucedo, Doria Thompson, Griselle Torres-Garcia, Xiaohong Wang, Carlos Castillo-Chavez

“…The uncertainties associated with the reported and expected levels of morbidity and mortality with this novel A-H1N1 live in a backdrop of $36,000$ deaths, over 200,000 hospitalizations, and millions of infections (20% of the population) attributed to seasonal influenza in the USA alone, each year. …”
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Prevalence and Determinants of Home Delivery among Women with Easy Access to Health Facilities in Sub-Saharan African Countries: A Multi-level Mixed Effect Analysis by Berhan Tekeba, Alebachew Ferede Zegeye, Deresse Abebe Gebrehana, Tadesse Tarik Tamir

“…Introduction: Most maternal deaths are associated with home deliveries, which account for half of births in low-income countries. …”
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A Risk Management Approach to Global Pandemics of Infectious Disease and Anti-Microbial Resistance by Annie Sparrow, Meghan Smith-Torino, Samuel M. Shamamba, Bisimwa Chirakarhula, Maranatha A. Lwaboshi, Christine Stabell Benn, Konstantin Chumakov

“…The World Health Organization (WHO), part of the One Health alliance, focuses mainly on antibiotics and vaccines to reduce deaths due to superbugs and largely ignores the critical role of chlorine to control water-borne diseases (including polio) and other infections. …”
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Systematic analysis and prediction of the burden of Alzheimer’s disease and other dementias caused by hyperglycemia by Dongying He, Dongying He, Manting Liu, Yujin Tang, Xiaona Tian, Lisi Zhou, Yizhen Chen, Xiaoxia Liu, Xiaoxia Liu

“…A Shiny platform was developed to visualize the disease burden and trends across 204 countries and regions.ResultsIn 2021, approximately 15% of ADOD deaths and disability-adjusted life years (DALYs) were attributed to HFPG, a 271.05% increase from 1990. …”
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Immunogenic Evaluation of Ribosomal P-Protein Antigen P0, P1, and P2 and Pentameric Protein Complex P0-(P1-P2)2 of Plasmodium falciparum in a Mouse Model by Agnieszka Szuster-Ciesielska, Leszek Wawiórka, Dawid Krokowski, Nikodem Grankowski, Łukasz Jarosz, Urszula Lisiecka, Marek Tchórzewski

“…Plasmodium falciparum, a protozoan parasite with a complex life cycle and high genetic variability responsible for the difficulties in vaccine development, is implicated in most malaria-related deaths. In the course of study, we prepared a set of antigens based on P-proteins from P. falciparum and determined their immunogenicity in an in vivo assay on a mouse model. …”
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Determinants of appropriate complementary feeding practices among mothers of children aged 6–23 months in Bokoji town, Oromia region, Ethiopia by Abdurehman Kalu Tololu, Bekele Teshome, Hiwot Zelalem Fessaha, Abdene Weya Kaso

“…Appropriate complementary feeding practices have the potential to prevent 6% of all deaths among children 6–23 months, particularly in developing countries. …”
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A 32-year trend analysis of lower respiratory infections in children under 5: insights from the global burden of disease study 2021 by Yan Wang, Ruiyang Han, Xiao Ding, Junli Chen, Wenjia Feng, Chunping Wang, Runguo Gao, Anning Ma, Anning Ma

“…Additionally, frontier analysis is used to visually depict the potential for burden reduction in each country or region based on their level of development.ResultsIn 2021, the global burden of lower respiratory infections in children under 5 years old included 37,828,159 incidence cases, 501,909.50 deaths, and 44,779,174.70 disability-adjusted life years. …”
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A qualitative study to explore healthcare providers' perspectives on barriers and enablers to early detection of breast and cervical cancers among women attending primary healthcar... by Gugulethu Tshabalala, Charmaine Blanchard, Keletso Mmoledi, Desiree Malope, Daniel S O'Neil, Shane A Norris, Maureen Joffe, Janan Janine Dietrich

“…Low-and-middle income countries (LMICs) contribute approximately 70% of global cancer deaths, and the cancer incidence in these countries is rapidly increasing. …”
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A novel marker to determine arrhytmia risk in elite cyclists: T peak T end by Bulent Isık, Z. İsik Solak Gormus, Huseyin Aslan, Abdullah Iclı, Galip Bilen Kurklu, Ozgur Cıftcı, Turhan Togan

“…If the hypertrophic cardiomyopathy is not diagnosed and treated, it can lead to sudden deaths in athletes. Not so much data is known whether or not it is favorable to use of Tp-e values in order to reflect the arrhythmia risks in asymptomatic elite cyclists. …”
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Targets of influenza human T-cell response are mostly conserved in H5N1 by John Sidney, A-Reum Kim, Rory D. de Vries, Bjoern Peters, Philip S. Meade, Florian Krammer, Alba Grifoni, Alessandro Sette

“…Based on these observations, and the overall similarity of the neuraminidase (NA) N1 subtype encoded in both HPAI and seasonal H1N1 influenza virus as well as cross-reactive group 1 HA stalk-reactive antibodies, we expect that a degree of pre-existing immunity is present in the general human population that could blunt the severity of human H5N1 infections.IMPORTANCEInfluenza A viruses (IAVs) cause pandemics that can result in millions of deaths. The highly pathogenic avian influenza (HPAI) virus of the H5N1 subtype is presently among the top viruses of pandemic concern, according to the WHO and the National Institute of Allergy and Infectious Diseases (NIAID). …”
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Transarterial Chemoembolization Plus Radiofrequency Ablation and Iodine-125 Seed Implantation for Hepatocellular Carcinoma in High-Risk Locations: A Propensity Score-Matched Analys... by Zhang G, Ren Y, Liu J, Cao Y, Xiong F, Liang B, Zheng C, Kan X

“…There was no occurrence of major complications or procedure-related deaths in the two groups.Conclusion: Compared with the TACE-RFA treatment, TACE-RFA-125I should be a more effective treatment strategy for patients with unresectable HCC (≤ 5 cm) in high-risk locations.Keywords: radiofrequency ablation, transarterial chemoembolization, iodine-125 seed, hepatocellular carcinoma, high-risk locations…”
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Impact of maternal nutritional literacy and feeding practices on the growth outcomes of children (6–23 months) in Gujranwala: a cross-sectional study by Aaiza Tahreem, Allah Rakha, Rimsha Anwar, Roshina Rabail, Cristina Maria Maerescu, Claudia Terezia Socol, Florin Leontin Criste, Gholamreza Abdi, Rana Muhammad Aadil

“…IntroductionMalnutrition contributes to approximately 45% of deaths among under 5 years children in low and middle-income countries. …”
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Hemoglobin glycation index and mortality risk in metabolic dysfunction-associated steatotic liver disease patients: a novel U-shaped association by Mengjie Zhao, Ning Sun, Yurong Cheng, Wantong Zhang, Jinjin Ji, Qiuyan Li, Fang Lu, Weiliang Weng

“…Over a median follow-up duration of 97.0 months, there were 1,352 recorded deaths, among which 386 were attributed to cardiovascular disease (CVD). …”
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The Role of Immunohistochemistry for AMACR/p504s and p63 in Distinguishing Prostate Cancer from Benign Prostate Tissue Samples in Botswana by Ramatlho P, Rugemalila MM, Tawe L, Pain D, Choga OT, Ndlovu AK, Koobotse MO, Lal P, Rebbeck TR, Paganotti GM, Narasimhamurthy M, Kyokunda LT

“…Chan School of Public Health, Boston, MA, USA; 9Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USACorrespondence: Pleasure Ramatlho, Pleasure Ramatlho School of Allied Health Professions, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana, Tel +26777572242, Email pleasureram@gmail.comIntroduction: Prostate cancer (CaP) is the most common malignancy and the second leading cause of cancer-related deaths among men in Botswana. Currently, diagnosing CaP relies on examining prostate biopsy samples, which can be challenging due to benign mimics. …”
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Adherence and efficacy outcomes in young Australians with suicidal ideation using a self-management app and digital engagement strategy compared with a sham app: a three-arm random... by Michelle Torok, Lauren McGillivray, Daniel Z.Q. Gan, Jin Han, Sarah Hetrick, Quincy J.J. Wong

“…Serious adverse events (hospital presenting non-suicidal self-harm and/or suicide attempts) were reported by 6% of participants during the trial (control condition: 9%; combined intervention condition: 4%). No deaths were reported. Interpretation: A third wave CBT app helped to reduce ideation severity, however providing additional online resources to promote therapeutic engagement did not enhance these effects. …”
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