Global burden of five major types of gastrointestinal cancer by Arjun Singh

“…Gastrointestinal (GI) cancers cause major global morbidity and mortality, with over 5 million new cases and 3.5 million deaths in 2020. The most prevalent GI malignancies are colorectal, gastric, liver, oesophageal, and pancreatic cancers. …”
Get full text

Water Cycle Bat Algorithm and Dictionary-Based Deformable Model for Lung Tumor Segmentation by Mamtha V. Shetty, D. Jayadevappa, G. N. Veena

“…Among the different types of cancers, lung cancer is one of the widespread diseases which causes the highest number of deaths every year. The early detection of lung cancer is very essential for increasing the survival rate in patients. …”
Get full text

Influence of Aging and Immune Alterations on Susceptibility to Pneumococcal Pneumonia in the Elderly by Nathan Kang, Veedamali S. Subramanian, Anshu Agrawal

“…<i>Streptococcus pneumoniae</i>, a Gram-positive diplococcus, is the leading cause of pneumonia-related deaths in older adults. Management of <i>S. pneumoniae</i> infections in the elderly is challenging due to impaired antibody responses to polysaccharides and surface proteins, compounded by rising antibiotic resistance. …”
Get full text

Epidemiological Profile of Patients with Cutaneous Melanoma in a Region of Southern Brazil by Marcelo Moreno, Ricardo Ludwig Schmitt, Maria Gabriela Lang, Vanessa Gheno

“…Cutaneous melanoma (CM) is responsible for 75% of deaths from malignant skin cancer. The incidence of CM in the southern region of Brazil, particularly in the western region of Santa Catarina, is possibly higher than estimated. …”
Get full text

Fourier Transformation-Based Analysis of X-Ray Diffraction Pattern of Keratin for Cancer Detection by Alexander Alekseev, Oleksii Avdieiev, Sasha Murokh, Delvin Yuk, Alexander Lazarev, Daizie Labelle, Lev Mourokh, Pavel Lazarev

“…With the growing number of cancer cases and deaths around the world, fast, non-invasive, and inexpensive screening is paramount. …”
Get full text

Signet Ring Cell Carcinoma of the Colon in Young Adults: A Case Report and Literature Review by Farida Abi Farraj, Hadi Sabbagh, Tarek Aridi, Najla Fakhruddin, Fadi Farhat

“…Colorectal cancer (CRC), one of the leading causes of cancer-related deaths, presents with challenging features related to its diagnosis and management. …”
Get full text

Proposing a new anti-Covid-19 agent by using molecular docking and dynamics simulations by Izabella Rodrigues Fonseca da Silva, Luís Felipe Guerreiro Martins, Julliane Yoneda

“…Abstract The Covid-19 pandemic, caused by SARS-CoV-2, was responsible for millions of deaths worldwide. The main protease (Mpro) of SARS-CoV-2 is considered one of the important drug targets for the treatment of Covid-19. …”
Get full text

Molecular landscape of lung cancer: insights into therapeutic targets and clinical outcomes by Saloni Mangal, Abhijit Debnath, Rupa Mazumder, Avijit Mazumder, Rajesh Kumar Singh, Jahanvi Sanchitra, S.K. Asif Jan, Pratibha Pandey, Bimlesh Kumar, Anil Kumar Singh

“…Lung cancer is the leading cause of cancer-related deaths globally, accounting for 1.8 million fatalities in 2020. …”
Get full text

A Case of Prostatic Carcinoma Manifesting as Cutaneous Facial Nodule by Israel Antonio Esquivel-Pinto, Bertha Torres-Alvarez, Ramiro Jetzabel Gómez-Villa, Juan Pablo Castanedo-Cázares

“…Prostate cancer is the second most frequently diagnosed cancer worldwide and the fifth most common cause of cancer deaths among men. Cutaneous metastasis is an uncommon phenomenon in prostatic cancer, occurring in 0.06–0.3% of cases. …”
Get full text

Role of food protein-derived peptides in the treatment of colon cancer by Xue Deng, Jing Yang, Huayi Suo, Jiajia Song

“…Colon cancer is one of the leading causes of cancer-related deaths and the second most common cancer in Western countries. …”
Get full text

The burden and temporal trend of early onset pancreatic cancer based on the GBD 2021 by Zongbiao Tan, Yang Meng, Yanrui Wu, Junhai Zhen, Haodong He, Yu Pu, Jixiang Zhang, Weiguo Dong

“…Globally, the number of EOPC cases increased from 24,480 to 42,254, and the number of deaths increased from 17,193 to 26,996 between 1990 and 2021. …”
Get full text

Time to invest in cholera by Rebecca C. Stout, Nicholas Feasey, Marion Péchayre, Nicholas Thomson, Benson Z. Chilima

“…Malawi was one of the worst affected countries in 2022–2023 with the highest number of deaths due to cholera in the world. In this personal view, we look at Malawi as a case example to illustrate how current approaches lack sufficient investment. …”
Get full text

Atherogenic Index and High-Density Lipoprotein Cholesterol as Cardiovascular Risk Determinants in Rheumatoid Arthritis: The Impact of Therapy with Biologicals by Calin D. Popa, Elke Arts, Jaap Fransen, Piet L. C. M. van Riel

“…Cardiovascular (CV) diseases are a serious concern in rheumatoid arthritis (RA), accounting for approximately one-third to one-half of all RA-related deaths. Besides the attempts to identify new risk factors, the proper management of traditional CV risk factors such as dyslipidemia should become a priority in the periodic evaluation of every RA patient. …”
Get full text

Modelling the health, financial protection and equity impacts of upscaling the ACT NOW early intervention breast cancer pilot program in the Philippines: an extended cost-effective... by Blake Angell, Stephen Jan, Mark Woodward, Sanne Peters, Merel Kimman, Alexander Chye, Nirmala Bhoo Pathy, Herdee Gloriane C Luna, Soledad B Lim, Helen Monaghan, Corazon A Ngelangel

“…Per 100 000 women, 57 deaths and eight financial catastrophes were saved. …”
Get full text

Prognostic nutritional index as a predictor of cardiovascular and all-cause mortality in American adults with hypertension: results from the NHANES database by Jing Tang, Jing Tang, Long Yang, Guan-Ying Yang, Yan-Hong Li, You-Sen Zhu, Hui Li, Xiao-Ming Gao, Xiao-Ming Gao, Xiao-Ming Gao

“…Restricted cubic spline (RCS) curves to investigate the existence of a dose-response linear relationship between them.ResultDuring a median follow-up period of 89 months, a total of 1,444 (7.94%) cardiovascular deaths occurred and 5,171 (28.43%) all-cause deaths occurred. …”
Get full text

Response of South Asia PM2.5 pollution to ammonia emission changes and associated impacts on human health by Yuanlin Wang, Eiko Nemitz, Samuel J. Tomlinson, Edward J. Carnell, Liquan Yao, Janice Scheffler, Tomas Liska, Clare Pearson, Ulrike Dragosits, Chandra Venkataraman, Srinidhi Balasubramanian, Rachel Beck, Mark A. Sutton, Massimo Vieno

“…We estimate that 247,000 (227,000–265,000) premature deaths and US$ 66,000 (61,000–71,000) million economic losses through this pathway can be attributed to NH3 emissions. …”
Get full text

Cancer mortality trends after implementation of the national programme for dispensarization of certain groups of the adult population: a population-based study from arkhangelsk, no... by L. E. Valkova, M. L. Levit, V. M. Merabishvili, A. Yu. Pankrateva, M. V. Krupina, D. M. Dubovichenko, A. V. Agaeva, A. Yu. Ryzhov, E. F. Potekhina, M. Yu. Valkov

“…The interventional value of the DCGAP was positive in the case of a decrease in the linear trend in mortality between 2013 and 2017.Results. A total of 33,824 deaths were included in the analysis. 25106 (74.2%) patients died from iMN, the proportion of deaths from other causes varied from 14% for lung cancer to 83% for cervical and prostate cancer. …”
Get full text

Immunotherapeutic Approaches in Triple-Negative Breast Cancer: State of the Art and Future Perspectives by Karima Oualla, Loay Kassem, Lamiae Nouiakh, Lamiae Amaadour, Zineb Benbrahim, Samia Arifi, Nawfel Mellas

“…It accounts for 15%–20% of all breast cancers and is associated with an aggressive evolution and poor outcomes with the majority of recurrences and deaths occurring in the first 5 years. Chemotherapy remains the mainstay of treatment in the absence of effective targets, but the good understanding of immune tumor microenvironment, the identification of immune-related targets, and the role of tumor-infiltrating lymphocytes (TILs) in TNBC has allowed to develop promising immunotherapeutic strategies for this unique subset of breast cancer. …”
Get full text

First isolation and characterization of SARS-CoV-2 from COVID-19 patient of North East India by Aniruddha Jakharia, Biswajyoti Borkakoty, Sumi Pait, Gautam Baruah, Rahul Hazarika, Dipankar Biswas

“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) responsible for the current pandemic has resulted in over 5 million deaths globally. More than a year has passed, still SARS-CoV-2 panic the public life. …”
Get full text

Endothelial activation and dysfunction caused by influenza A virus (<i>Alphainfluenzavirus influenzae</i>) by Vladimir A. Marchenko, Irina N. Zhilinskaya

“…Annual epidemics of influenza result in 3–5 million cases of severe illness and more than 600 000 deaths. Severe forms of influenza are usually characterized by vascular endothelial cells damage. …”
Get full text