Analyzing the impact of glycemic metabolic status on cardiovascular mortality and all-cause mortality related to the estimated glucose disposal rate: a nationwide cohort study by Shiming He, Shiming He, Shiming He, Chao Wang, Chao Wang, Chao Wang, Xin Huang, Xin Huang, Xin Huang, Guoan Jian, Guoan Jian, Guoan Jian, Zihao Lu, Zihao Lu, Zihao Lu, Kun Jiang, Kun Jiang, Kun Jiang, Guobo Xie, Guotai Sheng, Yang Zou

“…Finally, the predictive value of eGDR for mortality was assessed using receiver operating characteristic curves.ResultsDuring an average follow-up of 115 months, a total of 6,906 (15.01%) participants experienced all-cause mortality, with 1,798 (3.91%) deaths attributed to cardiovascular causes. Kaplan-Meier analysis revealed that higher eGDR levels were associated with gradually reduced mortality rates. …”
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The synergistic effect of the triglyceride-glucose index and a body shape index on cardiovascular mortality: the construction of a novel cardiovascular risk marker by Hao-ming He, Ying-ying Xie, Qiang Chen, Yi-ke Li, Xue-xi Li, Sun-jing Fu, Na Li, Yan-ru Han, Yan-xiang Gao, Jin-gang Zheng

“…Results A total of 673 (3.9%) cardiovascular deaths occurred during a median follow-up of 8.92 years. …”
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Comparison of objectively measured and estimated cardiorespiratory fitness to predict all-cause and cardiovascular disease mortality in adults: A systematic review and meta-analysi... by Ben Singh, Cristina Cadenas-Sanchez, Bruno G.G. da Costa, José Castro-Piñero, Jean-Philippe Chaput, Magdalena Cuenca-García, Carol Maher, Nuria Marín-Jiménez, Ryan McGrath, Pablo Molina-García, Jonathan Myers, Bethany Gower, Francisco B. Ortega, Justin J. Lang, Grant R. Tomkinson

“…Results: Forty-two studies representing 35 cohorts and 3,813,484 observations (81% male) (362,771 all-cause and 56,471 CVD deaths) were included. The pooled RRs for all-cause and CVD mortality per higher MET were 0.86 (95%CI: 0.83–0.88) and 0.84 (95%CI: 0.80–0.87), respectively. …”
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The state of paediatric deceased-organ donation at a South African tertiary public- sector hospital: A 14-year analysis by T Siyotula, J Barrell, K Manning, D Thomson, M McCulloch, T du Toit

“…During the study period, 156 in-hospital deaths were recorded in the trauma unit and 1 425 in the paediatric intensive care unit. …”
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Neural Correlates of Balance Skill Learning in Young and Older Individuals: A Systematic Review and Meta-analysis by Lisanne B. M. Bakker, Claudine J. C. Lamoth, Tomas Vetrovsky, Markus Gruber, Simone R. Caljouw, Ward Nieboer, Wolfgang Taube, Jaap H. van Dieën, Urs Granacher, Tibor Hortobágyi

“…Abstract Background Despite the increasing number of research studies examining the effects of age on the control of posture, the number of annual fall-related injuries and deaths continues to increase. A better understanding of how old age affects the neural mechanisms of postural control and how countermeasures such as balance training could improve the neural control of posture to reduce falls in older individuals is therefore necessary. …”
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Association of pre- and post-diagnosis dietary total antioxidant capacity (TAC) and composite dietary antioxidant index (CDAI) with overall survival in patients with ovarian cancer... by Dong-Dong Wang, Ming-Qian Jia, He-Li Xu, Yu Li, Jia-Xin Liu, Jia-Cheng Liu, Jia-Nan Sun, Fan Cao, Lang Wu, Fang-Hua Liu, Yi-Zi Li, Yi-Fan Wei, Xiao-Ying Li, Qian Xiao, Song Gao, Dong-Hui Huang, Tao Zhang, Ting-Ting Gong, Qi-Jun Wu

“…Results Among the total 560 patients with OC, there were 211 (37.68%) deaths during a median follow-up of 44.40 (interquartile range: 26.97–61.37) months. …”
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A prospective observational cohort study of HIV infection in Indonesia: baseline characteristics and one-year mortality by Tuti P. Merati, Evy Yunihastuti, Rudi Wisaksana, Nia Kurniati, Dona Arlinda, Muhammad Karyana, Nugroho H. Susanto, Dewi Lokida, Herman Kosasih, Aly Diana, Lois E. Bang, Melinda Setiyaningrum, Desrinawati M. Amin, Eppy Eppy, Wiwit A. S. N. Cahyawati, Emon W. Danudirgo, I Made Gede Darmaja, Nur Farhanah, Carta A. Gunawan, Usman Hadi, Kurnia F. Jamil, Sudirman Katu, Tambar Kembaren, I Gede Rai Kosa, Danang L. Norosingomurti, Asep Purnama, Ida S. Laksanawati, Adria Rusli, I Ketut Agus Somia, Yanri W. Subronto, Ivan L. Toruan, Renee Ridzon, C. Jason Liang, Aaron T. Neal, Ray Y. Chen, INA-PROACTIVE Study Group

“…Despite this progress, AIDS-related deaths among people living with HIV (PLWH) increased from 3.4% in 2010 to 4.8% in 2020. …”
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Harmful newborn cord care practices and associated factors among mothers who gave birth in the last six months in Chencha town, Southern Ethiopia: a mixed-methods study by Misgana Seifu, Sultan Hassen, Mekdim Kassa, Yosef Haile, Zeleke Girma, Temesgen Mohammed Toma, Agune Ashole, Mintesinot Melka Gujo, Wondimagegn Taye Dema, Aleme Mekuriya, Endashaw Shibru

“…BackgroundHarmful substance-related infections that cause neonatal deaths on the umbilical stump continue to be a major cause of worry, accounting for a large portion of the yearly mortality toll in developing nations such as Ethiopia. …”
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Dietary protein intake and PM2.5 on ovarian cancer survival: A prospective cohort study by He-Li Xu, Yi-Fan Wei, Qi Bao, Ya-Li Wang, Xiao-Ying Li, Dong-Hui Huang, Fang-Hua Liu, Yi-Zi Li, Yue-Yang Zhao, Xin-Xin Zhao, Qian Xiao, Song Gao, Ren-Jie Chen, Ling Ouyang, Xia Meng, Xue Qin, Ting-Ting Gong, Qi-Jun Wu

“…Results: During a median follow-up of 37.60 months, 123 deaths were documented. As for all-cause mortality, the multivariate-adjusted HRs (95 % CIs) in the highest vs. the lowest tertile were 0.57 (0.35–0.93), 0.60 (0.36–0.99), and 0.58 (0.37–0.90) for intakes of fish, egg, as well as fruit/vegetable protein, respectively (all P for trend < 0.05). …”
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Seroprevalence against SARS-CoV-2 after booster vaccination in a prison in Alicante (Spain) by Ana C. Montagud, Raul Moragues, Nancy Vicente-Alcalde, Nancy Vicente-Alcalde, Emilia Montagud, José Antonio Hurtado-Sánchez, José Antonio Hurtado-Sánchez, José Tuells, José Tuells

“…The COVID-19 pandemic has been characterized by high transmissibility and clinical severity resulting in a high number of infections and deaths worldwide. Vaccination has been a crucial tool in mitigating its devastating effects. …”
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Gambaran Perubahan Tekanan Darah Pasca Olahraga Futsal pada Mahasiswa Fakultas Kedokteran Universitas Andalas by Akdri Andi, Afriwardi ., Detty iryani

“…A study has</em><em> </em><em>identified 60 sudden deaths after sports and 58 </em><em>we</em><em>re caused by cardiovascular disorders.…”
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Evaluation of pulmonary tuberculosis disease burden in Shenyang, China, 2023 by Huijie Chen, Haiyan Bi, Peng Li, Zhixing Yang, Lihai Wen, Baijun Sun, Wei Sun

“…The highest incidence was 107.00/105 in the group of the population aged 80 and above (X 2 = 1171.75, p<0.001). In 2023, 189 PTB deaths were reported in Shenyang, including 156 males and 33 females. …”
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Chemical Synthesis, Efficacy, and Safety of Antimalarial Hybrid Drug Comprising of Sarcosine and Aniline Pharmacophores as Scaffolds by Jean Baptiste Niyibizi, Peter G. Kirira, Francis T. Kimani, Fiona Oyatsi, Joseph K. Ng’ang’a

“…According to the WHO report of 2015, there were 214 million cases of malaria with 438,000 deaths worldwide. Ninety percent of world’s malaria cases occur in Africa, where the disease is recognized as a serious impediment to economic and social development. …”
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HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma by Michal Frelich, Marek Bebej, Jan Pavlíček, Filip Burša, Vojtěch Vodička, Zdeněk Švagera, Adéla Kondé, Ondřej Jor, Markéta Bílená, Tereza Romanová, Peter Sklienka

“…Abstract Massive bleeding causes approximately 50% of deaths in patients with major trauma. Most patients die within 6 h of injury, which is preventable in at least 10% of cases. …”
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Prevalence and factors associated with potential clinically significant drug-drug interactions in patients with cardiovascular diseases at hospital admission by Marović Iva, Udovičić Mario, Rudan Diana, Manola Šime, Samardžić Ivana, Vrca Vesna Bačić, Hadžiabdić Maja Ortner, Marinović Ivana

“…It is estimated that 17.9 million people died from CVDs in 2019, which represents 32 % of all deaths worldwide. Cardiovascular drugs are the most common medical intervention for the prevention of cardiovascular events. …”
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Seasonal analysis of indoor and outdoor ratios of PM2.5 and PM10 in Bangkok and Chiang Mai: A comparative study of haze and non-haze episodes by Wissanupong Kliengchuay, Sarima Niampradit, Narut Sahanavin, William Mueller, Susanne Steinle, Miranda Loh, Helinor Jane Johnston, Sotiris Vardoulakis, San Suwanmanee, Walaiporn Phonphan, John W. Cherrie, Kraichat Tantrakarnapa

“…Particulate matter (PM) air pollution has been identified as one cause of human health impact with the estimated global 8.8 million attributable deaths. Thailand experiences haze episode every year, which can lead to high ambient concentrations of particulate matter in ambient air. …”
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Enhanced Antitumor Efficacy and Reduced Toxicity in Colorectal Cancer Using a Novel Multifunctional Rg3- Targeting Nanosystem Encapsulated with Oxaliplatin and Calcium Peroxide by Xie Y, Zhu M, Bao H, Chen K, Wang S, Dai J, Chen H, Li H, Song Q, Wang X, Yu L, Pei J

“…Yizhuo Xie,1 Ming Zhu,1 Han Bao,1 Kejia Chen,1 Shanshan Wang,1 Jingwen Dai,1 Hongzhu Chen,1 He Li,1 Qi Song,2 Xinlu Wang,2 Liangping Yu,2 Jin Pei1 1Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People’s Republic of China; 2Department of Clinical Pharmacy, the First Hospital of Jilin University, Changchun, People’s Republic of ChinaCorrespondence: Jin Pei, Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, People’s Republic of China, Tel +86-431-85619725, Email peijin@jlu.edu.cn Liangping Yu, Department of Clinical Pharmacy, the First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, 130061, People’s Republic of China, Tel +86 431 81879802, Email liangpingyu@jlu.edu.cnPurpose: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. Oxaliplatin (OXA) is currently the primary chemotherapeutic agent for CRC, but its efficacy is limited by the tumor microenvironment (TME). …”
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Evaluation of three novel antigens and costimulatory agents for improvement of M. Tuberculosis specific interferon gamma release assays by Sandra Schwarzlose-Schwarck, Mark Reinwald, Torsten Bauer, Florian Hentschel, Til Kiderlen, Dorinja Zapf, Victor Herbst, Stefan Lüth, David Krieger, Werner Dammermann

“…Abstract Background Mycobacterium tuberculosis (MT) infections represent a global health problem and latent tuberculosis infection (LTBI) affects an estimated 25% of the world population. 10.6 million people fell ill with tuberculosis (TB) worldwide in 2021 and a total of 1.6 million TB-associated deaths were reported. Thus, reliable diagnosis of LTBI is crucial to ensure adequate treatment. …”
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The impact of different gastrointestinal reconstruction techniques on gut microbiota after gastric cancer surgery by Yu Yang, Yu Yang, Hang-Yu Zhou, Guo-Min Zhou, Guo-Min Zhou, Jin Chen, Rui Ming, Dong Zhang, Huai-Wu Jiang, Huai-Wu Jiang

“…This is particularly significant in China, where a large proportion of global new cases of gastric cancer and related deaths occur. In recent years, with the continuous development of molecular biology technology, people have gained a deeper understanding of the gastrointestinal microbiome, and studies have shown that it is closely related to the occurrence, development, and therapeutic response of gastric cancer. …”
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AI-Driven Innovations for Early Sepsis Detection by Combining Predictive Accuracy With Blood Count Analysis in an Emergency Setting: Retrospective Study by Tai-Han Lin, Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Hung-Hsin Lin, Chiung-Tzu Yen, Sheng-Hui Tang, Pin-Ching Pan, Cherng-Lih Perng, Feng-Yee Chang, Chien-Wen Chen, Hung-Sheng Shang

“… BackgroundSepsis, a critical global health challenge, accounted for approximately 20% of worldwide deaths in 2017. Although the Sequential Organ Failure Assessment (SOFA) score standardizes the diagnosis of organ dysfunction, early sepsis detection remains challenging due to its insidious symptoms. …”
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