Dietary sodium-to-potassium ratio as a risk factor for stroke, cardiovascular disease and all-cause mortality in Japan: the NIPPON DATA80 cohort study by Hirofumi Ohnishi, Yoshitaka Murakami, Katsuyuki Miura, Koji Tamakoshi, Hirotsugu Ueshima, Akira Okayama, Tomonori Okamura, Takayoshi Ohkubo, Toshiyuki Ojima, Yoshihiro Miyamoto, Maryam Zaid, Aya Kadota, Akira Fujiyoshi, Yosikazu Nakamura, Naoyuki Takashima, Atsushi Hozawa, Shigeyuki Saitoh, Yutaka Kiyohara, Fumiyoshi Kasagi, Nagako Okuda, Takehito Hayakawa, Hiroshi Akasaka, Yusuke Arai, Katsushi Yoshita, Kiyomi Sakata, Nobuo Nishi, Toru Izumi, Yasuhiro Matsumura, Hideaki Nakagawa, Yoshikuni Kita, Naomi Miyamatsu, Yasuyuki Nakamura, Kazunori Kodama

“…Age-adjusted and multivariable-adjusted HRs were calculated using the Mantel-Haenszel method and Cox proportional hazards model.Primary outcome measures Mortality from total and subtypes of stroke, CVD and all causes.Results A total of 1938 deaths from all causes were observed over 176 926 person-years. …”
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Ocular and Mucocutaneous Sequelae among Survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo by Bayaki Saka, Abla Séfako Akakpo, Julienne Noude Teclessou, Garba Mahamadou, Abas Mouhari-Toure, Kossi Dzidzinyo, Adam Nouhou Diori, Nidain Maneh, Sabin Prince-Agbodjan, Koussake Kombaté, Komi Balo, Kissem Tchangai-Walla, Palokinam Pitché

“…Sixty-four (52,5%) of the 122 patients, who had been examined by an ophthalmologist during the acute stage, had acute ocular involvement, which was mild in 27.9% of patients, moderate in 13.1%, and severe in 11.5%. We recorded 17 deaths (i.e., three cases of SJS, 12 of TEN, and two of SJS/TEN overlap), including 11 cases of HIV infected patients. …”
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Analysis of the safety and efficacy of flow diverter device in the treatment of tandem aneurysms in the internal carotid artery by Jun Wan, Jun Wan, Ligang Xu, Yeqing Jiang, Lei Zhang, Zhenyu Wang, Xiaolong Zhang, Shengzhang Wang, Shengzhang Wang

“…All patients were followed up clinically for a median of 25.5 months (15.5–28.7 months). There were no deaths and symptomatic complications. The modified Rankin Scale scores (mRS) of 16 patients were all less than 2. …”
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Karakteristik Penderita Penyakit Jantung Bawaan pada Anak di RSUP Dr. M. Djamil Padang Periode Januari 2010 – Mei 2012 by Nur Ain, Didik Hariyanto, Sovina Rusdan

“…<br />Kata kunci: penyakit jantung bawaan, anak, variasi karakteristik <br /><br /><br />Abstract <br />Congenital heart disease (CHD) is a common birth defect, and a leading cause of deaths linked to birth defects. Many studies show that the presence of significant geographic variation in the incidence of CHD. …”
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The Impact of Nutritional Status and Tumor-Infiltrating Lymphocytes (CD4+ and CD8+) on Chemotherapy Response in Colorectal Cancer Patients by Lukman K, Septianto R, Rudiman R, Ruchimat T, Sribudiani Y, Nugraha P, Primastari E, Budiman D

“…Nutritional status, levels of CD4+ and CD8+ were significantly associated with chemotherapy responses in CRC patients (p< 0.001).Conclusion: Nutritional status and elevated TIL levels (CD4+/CD8+) positively correlate with better chemotherapy response in CRC patients.Plain Language Summary: Colorectal cancer is the second leading cause of cancer-related deaths worldwide, with 1.9 million new cases reported annually, according to the World Health Organization. …”
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Intention to vaccinate against COVID-19 and adherence to non-pharmaceutical interventions against COVID-19 prior to the second wave of the pandemic in Uganda: a cross-sectional stu... by Ambrose Talisuna, Solome Okware, Rhoda K Wanyenze, Solomon Tsebeni Wafula, Innocent B Mugume, Benjamin Sensasi, Alexander Chimbaru, Richard Kabanda, Tabley Bakyaita, Jayne Byakika-Tusiime

“…Objectives The resurgence in cases and deaths due to COVID-19 in many countries suggests complacency in adhering to COVID-19 preventive guidelines. …”
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Utilization of partograph and associated factors among obstetric caregivers in Ethiopia: a systematic review and meta-analysis by Mulat Ayele, Eyob Shitie Lake, Gizachew Yilak, Getinet Kumie, Biruk Beletew Abate, Alemu Birara Zemariam, Befkad Derese Tilahun

“…However, in Ethiopia, the prevalence of obstructed labor is much higher at 11.8% and contributes to 14.4% of the total maternal deaths due to underutilization of the partograph by obstetric caregivers. …”
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Exploring and detecting predictors associated with survival and mortality of cervical cancer patients: a 10-year retrospective study by Shaba Muneeha, Raushan Kumar Chaudhary, Vijith Vittal Shetty, Soumya Patil, Uday Venkat Mateti

“…In India, approximately 123,907 women are diagnosed with cervical cancer every year, leading to 77,348 deaths annually. However, Indian healthcare system lacks the sufficient information regarding the factors influencing survival and mortality among cervical cancer patients at regional levels. …”
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Protein Level and Infantile Diarrhea in a Postweaning Piglet Model by Jing Gao, Jie Yin, Kang Xu, Hui Han, ZeMin Liu, ChenYu Wang, TieJun Li, YuLong Yin

“…Infantile diarrhea is a serious public health problem around worldwide and results in millions of deaths each year. The levels and sources of dietary protein are potential sources of diarrhea, but the relationship between the pathogenesis causes of infantile diarrhea and protein intake remains poorly understood. …”
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Design, synthesis, structural characterization, in vitro anticancer activity, and in silico studies of some new hydroxylated and fluorinated-substituted hydrazone derivatives by Reşit Çakmak, Eyüp Başaran, Ömer Erdoğan, Suraj N. Mali, Semiha Köprü, Haya Yasin, Shailesh S. Gurav, Giray Topal

“…Today, due to improved lifestyles and increased survival, the number of new cancer cases and cancer-related deaths continues to increase. In this study, novel hydroxylated and fluorinated-substituted hydrazone derivatives bearing an aromatic nitro moiety (2a-d and 3a-d) were designed as potential anticancer drug candidates, synthesized for the first time, and evaluated for their anticancer activity against chondrosarcoma (SW1353), a common primary malignant cartilage-forming tumor, neuroblastoma (SH-SY5Y), a type of brain cancer, and healthy (L929) cell lines using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method for 24 h. …”
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Needs Assessment and Tailored Training Pilot for Emergency Care Clinicians in the Prehospital Setting in Rwanda by Naz Karim, Jeanne D’Arc Nyinawankusi, Mikaela S. Belsky, Pascal Mugemangango, Zeta Mutabazi, Catalina Gonzalez Marques, Angela Y. Zhang, Janette Baird, Jean Marie Uwitonze, Adam C. Levine

“…Background: In low- and middle-income countries (LMIC), 45% of deaths could be addressed by implementation of an emergency medical services (EMS) system. …”
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Comparative- and Cost-Effectiveness Research Determining the Optimal Intervention for Advancing Transgender Women With HIV to Full Viral Suppression (Text Me, Alexis!): Protocol fo... by Cathy J Reback, Thomas Blue, Ali Jalali, Raphael Landovitz, Michael J Li, Raymond P Mata, Danielle Ryan, Philip J Jeng, Sean M Murphy

“…These issues are exacerbated by comorbid conditions, such as substance use disorder, which is also associated with reduced quality of life, increased overdose deaths, usage of high-cost health care services, engagement in a street economy, and cycles of incarceration. …”
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Safety profile of sacituzumab govitecan in patients with breast cancer: A systematic review and meta-analysis by Maria Inez Dacoregio, Isabella Michelon, Caio Ernesto do Rego Castro, Francisco Cezar Aquino de Moraes, Guilherme Rossato de Almeida, Lis Victória Ravani, Maysa Vilbert, Ricardo Lima Barros Costa

“…Dose reductions and treatment discontinuation were reported in 22 % and 4 % of patients, respectively, and 19 deaths (2 %) were documented. Most of them were not deemed to be treated-related. …”
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“I believe it when there is an expert next to me:” a qualitative analysis on the perceptions and experiences of pregnant women to self-monitor blood pressure in Lombok, Indonesia... by Tigest Tamrat, Yuni Dwi Setiyawati, Maria Barreix, Nya’Jeumpa Madani, Antoine Geissbühler, Anuraj H. Shankar, Ozge Tuncalp

“…Abstract Background Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal deaths and require close monitoring of blood pressure (BP) to mitigate potential adverse effects. …”
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April 15th war and hemodialysis patients in Sudan: a cross-sectional study by Malaz Hassan Dafaalla Idrees, Moez Mohammed Ibrahim Bashir, Balqees Abdeen Ahmed Mohamed, Amal Essam Ali Ahmed, Hamid Mohieldin Mohamed Abdalla, Kamil Mirghani Ali Shaaban

“…Hemodialysis patients are among the most affected by this war’s aftermath, which ranges from obvious dangers like violence-related injuries and deaths to more indirect effects like the suspension of access to preventive and curative medical care. …”
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Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021 by Qi Zhang, Lan Luo, Lai-lai Yan, Lai-lai Yan, Jing Guo, Hui-jun Wu, Zi-wei Zhang, Yu-hua Zhu, Rui Qiao, Rui Qiao

“…BackgroundTo evaluate global, regional, and national trends in the burden of neonatal diseases attributable to LBW, as well as associated health inequalities, from 1990 to 2021.MethodsUsing data from the Global Burden of Disease Study (GBD2021), we analyzed deaths and DALYs due to LBW-attributable neonatal diseases. …”
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Feasibility of a Mobile App–Based Cognitive-Behavioral Perinatal Skills Program: Protocol for Nonrandomized Pilot Trial by Andrea B Temkin-Yu, Aliza Ayaz, Ella Blicker, Michael X Liu, Ace Oh, Isabelle E Siegel, Meredith J Seewald, Alison D Hermann, Soudebah Givrad, Lara M Baez, Lauren M Osborne, Cori M Green, Maddy M Schier, Alexandra M Davis, Shasha Zhu, Avital Falk, Shannon M Bennett

“… BackgroundMental illness is one of the top causes of preventable pregnancy-related deaths in the United States. There are many barriers that interfere with the ability of perinatal individuals to access traditional mental health care. …”
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Predictors of late complications after coronary artery bypass grafting in patients with stable coronary heart disease by O.J. Zharinov, К.O. Mikhaliev, O.A. Yepanchintseva, B.M. Todurov

“…In general, 29 late complications (3 cases of heart failure, 3 – first diagnosed atrial fibrillation (AF), 4 – acute coronary syndrome, 11 – left ventricular ejection fraction (LV EF) relative decrease more than 10 %, 2 – formation of atrial fibrillation permanent form, 2 – acute myocardial infarction and 4 deaths) were diagnosed in 24 patients. Groups of patients with and without complications were compared according to demographic parameters, risk factors, concomitant diseases, laboratory parameters, features of the CABG operation and postoperative therapy. …”
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Global, regional and national burden of neuroblastoma and other peripheral nervous system tumors, 1990 to 2021 and predictions to 2035: visualizing epidemiological characteristics... by Chaoyan Yue, Qi Zhang, Fenyong Sun, Qiuhui Pan

“…Background: Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children, accounting for >15 % of cancer-related deaths in children. We analyzed the epidemiological statistical indicators of neuroblastoma and other peripheral nervous system tumors patients from 1990 to 2021 in Global Burden of Disease (GBD) 2021 database, aiming to provide valuable insights for public health interventions and clinical practices. …”
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Association of different insulin resistance surrogates with all-cause and cardiovascular mortality among the population with cardiometabolic multimorbidity by Hongqiang Zhang, Zhixin Tu, Sihua Liu, Jumei Wang, Jie Shi, Xingyu Li, Rongdongqing Shi, Minghui Chen, Tong Yue, Sihui Luo, Yu Ding, Xueying Zheng

“…Results Of the 477 all-cause deaths that occurred during a median follow-up of 5.8 years, 197 were related to cardiovascular disease. …”
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