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5281
Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings...
Published 2022-07-01“…Introduction Every year 2.4 million deaths occur worldwide in babies younger than 28 days. …”
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5282
Temporal trends and future projections of incidence rate and mortality for asthma in China: an analysis of the Global Burden of Disease Study 2021
Published 2025-01-01“…Future healthcare strategies must address the aging population to manage the projected increase in asthma cases and deaths.…”
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5283
Sources of PM2.5 exposure and health benefits of clean air actions in Shanghai
Published 2025-01-01“…We estimate that a 10% decrease in anthropogenic emissions throughout China avoids over 752 (506–1,044) PM2.5-related premature deaths in Shanghai, with changes in local emissions potentially saving 241 (161–334) lives. …”
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5284
Pre-clinical study of curcumin in the treatment of gastric Cancer
Published 2025-02-01“…Gastric cancer is the fifth most common cancer globally and the third leading cause of cancer-related deaths. Researchers have been investigating natural compounds as potential alternatives to traditional cancer treatments, including surgery, radiation, and chemotherapy. …”
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5285
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment
Published 2025-01-01“…Abstract With breast cancer being the most common tumor among women in the world today, it is also the leading cause of cancer-related deaths. Standard treatments include chemotherapy, surgery, endocrine therapy, and targeted therapy. …”
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5286
Bromodomain-Containing Protein 4: A Dynamic Regulator of Breast Cancer Metastasis through Modulation of the Extracellular Matrix
Published 2012-01-01“…Metastasis is an extremely complex process that accounts for most cancer-related deaths. Malignant primary tumors can be removed surgically, but the cells that migrate, invade, and proliferate at distant organs are often the cells that prove most difficult to target therapeutically. …”
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5287
Statistical Insights Into Machine Learning-Based Box Models for Pregnancy Care and Maternal Mortality Reduction: A Literature Survey
Published 2024-01-01“…It is the number of preventable deaths that occur each year due to pregnancy and childbirth. …”
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5288
Dynamical Models for Infectious Diseases with Varying Population Size and Vaccinations
Published 2012-01-01“…By a useful bifurcation theorem, we acquire the existence of the endemic periodic solutions when the disease-related deaths do not occur. At last, we compare the results with vaccinations and without vaccinations and illustrate our results by numerical simulations.…”
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5289
Trafficked Proteins—Druggable in Plasmodium falciparum?
Published 2013-01-01“…Annually this parasitic disease leads to more than half a million deaths; most of these are children in Africa. An effective vaccine is not available, and the treatment of the disease is solely dependent on chemotherapy. …”
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5290
Diagnosis and treatment of cerebral vasospasm after subarachnoid hemorrhage
Published 2023-12-01“…Stroke secondary to vasospasm accounts for almost half of the early deaths after subarachnoid hemorrhage. The timely diagnosis of vasospasm is paramount in the implementation of treatment modalities. …”
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5291
First Presentation of Systemic Lupus Erythematosus in a 24-Year-Old Male following mRNA COVID-19 Vaccine
Published 2022-01-01“…The SARS-CoV-2 viral pandemic has had an immeasurable global impact, resulting in over 5 million deaths worldwide. Numerous vaccines were developed in an attempt to quell viral dissemination and reduce symptom severity among those infected. …”
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5292
Melanoma Disparities among US Hispanics: Use of the Social Ecological Model to Contextualize Reasons for Inequitable Outcomes and Frame a Research Agenda
Published 2016-01-01“…Cutaneous melanoma is a significant public health concern, accounting for thousands of deaths annually in the US. Early detection and diagnosis are critical given the poor prognosis and limited treatment options of advanced-stage disease. …”
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5293
A Novel Extended Susceptible, Exposed, Infected, and Recovered Model with Surveys for Analysis of COVID-19 Pandemic in Rajasthan
Published 2024-04-01“…It already caused over 21 million confirmed cases and 758,000 deaths as of July 2021. Modeling frameworks, underlying assumptions, available datasets, and the region/time frame being modeled, predictions are possible, but the projections might vary widely, making it difficult to rely on one model universally way. …”
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5294
The Burden of Blood-Pressure-Related Cardiovascular Mortality in Mexico
Published 2014-01-01“…Also, approximately half of all cardiovascular deaths that occurred annually in the population of Mexico aged ≥50 years are attributable to above optimal levels of systolic blood pressure. …”
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5295
Mathematical Modelling and Analysis of Transmission Dynamics of Lassa Fever
Published 2020-01-01“…Clinical diseases, as well as high seroprevalence, have been documented in Nigeria, Sierra Leone, Liberia, Guinea, Ivory Coast, Ghana, Senegal, Upper Volta, Gambia, and Mali. Deaths from Lassa fever occur all year round but naturally peak during the dry season. …”
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5296
Association Between Single-Nucleotide Polymorphisms in <i>Toll-like Receptor 3</i> (<i>tlr3</i>), <i>tlr7</i>, <i>tlr8</i> and <i>tirap</i> Genes with Severe Symptoms in Children P...
Published 2024-12-01“…The global number of COVID-19 deaths has reached 7 million, with 4% of these deaths occurring in children and adolescents. …”
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5297
Assessing a bundle of peer counseling, mobile phone messages, and mama kits in promoting timely initiation of and exclusive breastfeeding in Uganda: A cluster randomized controlled...
Published 2025-01-01“…<h4>Background</h4>Timely initiation of and exclusive breastfeeding have been recommended as key interventions to enable countries to attain the sustainable development target of reducing neonatal mortality to no more than 12 deaths per 1000 live births and to reduce mortality of children under 5 years to no more than 25 deaths per 1000 live births.…”
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5298
The global, regional, and national burden of type 2 diabetes mellitus attributable to low physical activity from 1990 to 2021: a systematic analysis of the global burden of disease...
Published 2025-01-01“…Results Globally, the number of T2DM deaths and DALYs attributable to LPA were approximately 0.15 million and 5.52 million respectively in 2021, which more than doubled compared to 1990. …”
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5299
A Review of Dying for Freedom: Political Martyrdom in South Africa by Jacob Dlamini (Polity Press, 2024).
Published 2025-01-01“…Championed by the ideas of political activists like Nelson Mandela and Steve Biko, political deaths during apartheid were interpreted as one’s passport to a heroic legacy, an experience one had to look forward to. …”
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5300
Targeting EBV Episome for Anti-Cancer Therapy: Emerging Strategies and Challenges
Published 2025-01-01“…The EBV infection is associated with approximately 200,000 human cancer cases and 140,000 deaths per year. The presence of EBV in tumor cells provides a unique advantage in targeting the viral genome (also known as episome), to develop anti-cancer therapeutics. …”
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