FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregn... by Kerry Woolfall, Jamie J Kirkham, Jane Sandall, Mariana Popa, Enrico Lopriore, Mark Turner, Shakila Thangaratinam, Aris T Papageorghiou, Andrew Sharp, Lawrence Impey, Andy Healey, Jessica Mendoza, Asma Khalil, Dharmintra Pasupathy, Brigitte Vollmer, Zarko Alfirevic, Rajeswari Parasuraman, Jan Deprest, Richard Edmund Ashcroft, Kurt Hecher, Smriti Prasad, Baskaran Thilaganathan, Richard J Jackson, Tracy Karen Mitchell, Natasha Fenwick, Monique C Haak, Liesbeth Lewi, Shauna Leven, Fabricio Da Silva Costa, Odai Yaghi, Tracey Ricketts, George Attilakos, Carolyn Bailie, Christine Cornforth, Mark Denbow, Louise Hardman, Jane Harrold, Joel Marsden, Tommy Mousa, Surabhi Nanda, Michelle Watson, Karen Wilding, Dilly Anumba, Edward D Johnstone, Yoav Yinon, Ahmet Baschat

“…The condition poses unique management difficulties: on the one hand, continuation of the pregnancy carries a risk of death of the smaller twin, with a high risk of co-twin demise (40%) or co-twin neurological sequelae (30%). …”
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Contribution of cuproptosis and immune-related genes to idiopathic pulmonary fibrosis disease by Chengji Jin, Jia Li, Qiaoyu Li, Lipeng Zhang, Shaomao Zheng, Qiong Feng, Yongjie Li, Yu Zheng, Qiuli Nie, Jin Liang, Jing Wang, Jing Wang

“…Cuproptosis, a novel form of copper-induced cell death, has garnered attention for its potential implications. …”
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Smart design in biopolymer-based hemostatic sponges: From hemostasis to multiple functions by Chen-Yu Zou, Chen Han, Fei Xing, Yan-Lin Jiang, Ming Xiong, Jesse Li-Ling, Hui-Qi Xie

“…Uncontrolled hemorrhage remains the leading cause of death in clinical and emergency care, posing a major threat to human life. …”
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Time-Zero Biopsies in Deceased-Donor Kidney Transplantation: Predictive Value of Histological Findings on Long-Term Graft Function by Bárbara Beirão, Henrique Borges, Joana Trigo Medeiros, Filipa Fonte Rodrigues, Ana Pena, Mário Góis, Helena Viana, Cristina Jorge

“…Nineteen biopsies were excluded due to recipient death before 3 years. We examined donor and recipient-related characteristics and histological findings categorized using the Banff scoring system. …”
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E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis by Ashley L. Comiford, DrPH, Dorothy A. Rhoades, MD, MPH, Justin D. Dvorak, PhD, Kai Ding, PhD, Noah Collins, Alexandra L. Blair, Mark P. Doescher, MD, MSPH

“…Introduction: Tobacco use is the leading cause of death in the U.S., and American Indian/Alaska Native people have high rates of tobacco-related diseases. …”
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Huntington Disease Health Related Quality of Life, Function and Well Being: The Patient’s Perspective by Jesús Pérez-Pérez, Sofía García-López, Tamara Fernández Valle, Cèlia Painous, Maria Rosa Querol-Pascual, Pedro J. García Ruiz, Elena Bellosta Diago, Esther Cubo Delgado, Barbara Vives Pastor, María Carmen Peiró Villaplana, Idaira Martín Santana, Marta Blázquez Estrada, Matilde Calopa Garride, Pablo Mir, Carmen Álvarez, Jorge Maurino, Anna de Prado, José Luis López-Sendón

“…HDQLIFE domain score means (SD) includes concern with death and dying 45.97 (9.60) end-of-life planning 37.91 (8.84), and meaning and purpose 44.74 (9.05). …”
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A phase III, randomized, controlled noninferiority trial to study the efficacy and safety of imipenem/cilastatin/relebactam (IMI/REL) vs piperacillin/tazobactam (PIP/TAZ) in patien... by Junjie Li, Feng Wei, Peng Xiang, Zhengang Tang, Lianshu Ding, Luke Francis Chen, Maria Losada, Zlatka Iamboliyska, Fang Sun, Mingfen Zhu, Xiaodan Guo, Xiaoling Du, Chang Chen, Christopher Bruno, Sandra Koseoglu, Katherine Young, Min Zhou, Jieming Qu

“…Secondary outcomes were comparable between treatment groups, including favorable CR and MR. AEs resulting in death were generally consistent with pre-existing or underlying illness. …”
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TP53 Mutation Predicts Worse Survival and Earlier Local Progression in Patients with Hepatocellular Carcinoma Treated with Transarterial Embolization by Ken Zhao, Anita Karimi, Luke Kelly, Elena Petre, Brett Marinelli, Erica S. Alexander, Vlasios S. Sotirchos, Joseph P. Erinjeri, Anne Covey, Constantinos T. Sofocleous, James J. Harding, William Jarnagin, Carlie Sigel, Efsevia Vakiani, Etay Ziv, Hooman Yarmohammadi

“…The time to progression with death or the last patient contact without progression as competing risks were used to obtain a cumulative incidence function, and the association with TP53 status was evaluated using the Gray test. …”
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Radiation to all macroscopic sites of tumor permits greater systemic antitumor response to in situ vaccination by Zachary S Morris, Paul M Sondel, Amy K Erbe, Alexander L Rakhmilevich, Amber M Bates, Peter M Carlson, Alexander A Pieper, Ravi B Patel, Jen Birstler, Joseph Grudzinski, Reinier Hernandez, Bryan P Bednarz, Jamey P Weichert, Arika S Feils, Matthew Rodriquez, Claire Sun, Ian Marsh

“…Tumor growth, overall survival, and cause of death were measured. Flow cytometry was used to evaluate immune population changes in both tumors.Results Abscopal effects of local ISV were amplified by delivering as little as 2–6 Gy of EBRT to the secondary tumor. …”
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Results of propagation of Fagus silvatica L. plants in vitro by Mykola Lisovyi, Andrii Ivaniuk

“…It was revealed that with an increased content of auxin or cytokinin or their absence in the nutrient medium, the death of the plant material of the species under study occurs. …”
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Clinical course, management and outcomes of COVID-19 in HIV-infected renal transplant recipients: A case series by L Bertels, K Manning, A Redd, T du Toit, Z Barday, E Muller

“…HIV‐infected kidney transplant recipients with COVID‐19 are at increased risk of acute illness and death owing to their underlying comorbidities and chronic immunosuppression. …”
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Serum hsa-miR-22-3p, hsa-miR-885-5p, Lipase-to-Amylase Ratio, C-Reactive Protein, CA19-9, and Neutrophil-to-Lymphocyte Ratio as Prognostic Factors in Advanced Pancreatic Ductal Ade... by Jakub Wnuk, Dorota Hudy, Joanna Katarzyna Strzelczyk, Łukasz Michalecki, Kamil Dybek, Iwona Gisterek-Grocholska

“…Pancreatic cancer (PC) is the seventh most common cause of cancer-related death worldwide. The low survival rate may be due to late diagnosis and asymptomatic early-stage disease. …”
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2′-Hydroxycinnamaldehyde induces ROS-mediated apoptosis in cancer cells by targeting PRX1 and PRX2 by Yae Jin Yoon, Yu-Jin Lee, Jiyeon Choi, Seung-Wook Chi, Sangku Lee, Kyung Chan Park, Byoung-Mog Kwon, Dong Cho Han

“…These findings demonstrate that PRX1 and PRX2 are molecular target proteins responsible for HCA-induced ROS elevation and cancer cell death.…”
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CCAAT/Enhancer-Binding Protein β Mediates Oxygen-Induced Retinal Neovascularization via Retinal Vascular Damage and Vascular Endothelial Growth Factor by Tingting Li, Xuan Cai, Xiangning Wang, Xueyan Zhang, Hui Zhang, Biwei Xu, Shiwei Li, Jianyan Hu, Qiang Wu

“…Compared with those of the rats with OIR in the LV.shScrambled group, nonperfused retinal areas, neovascular tufts, pericyte death, and the ratio of endothelial cells to pericytes in the LV.shC/EBP β group were significantly reduced. …”
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Prophylactic Subacute Administration of Zinc Increases CCL2, CCR2, FGF2, and IGF-1 Expression and Prevents the Long-Term Memory Loss in a Rat Model of Cerebral Hypoxia-Ischemia by Victor Manuel Blanco-Alvarez, Guadalupe Soto-Rodriguez, Juan Antonio Gonzalez-Barrios, Daniel Martinez-Fong, Eduardo Brambila, Maricela Torres-Soto, Ana Karina Aguilar-Peralta, Alejandro Gonzalez-Vazquez, Constantino Tomás-Sanchez, I. Daniel Limón, Jose R. Eguibar, Araceli Ugarte, Jeanett Hernandez-Castillo, Bertha Alicia Leon-Chavez

“…Prophylactic subacute administration of zinc decreases lipoperoxidation and cell death following a transient cerebral hypoxia-ischemia, thus suggesting neuroprotective and preconditioning effects. …”
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Influenza Immunization in Very-Low-Birth-Weight Infants: Epidemiology and Long-Term Outcomes by Marie-Theres Dammann, Hannah Kraft, Guido Stichtenoth, Kathrin Hanke, Michael Zemlin, Janina Soler Wenglein, Isabell Ricklefs, Alexander Herz, Alexander Humberg, Dorothee Viemann, Geraldine Engels, Matthias Volkmar Kopp, Folke Brinkmann, Carsten Fortmann-Grote, Wolfgang Göpel, Egbert Herting, Christoph Härtel, Ingmar Fortmann, on behalf of the German Neonatal Network

“…Background: Very-low-birth-weight infants (VLBWIs; birth weight < 1500 g) are at an increased risk of complicated influenza infection, which frequently includes pneumonia, encephalitis or even death. Data on influenza immunization and its outcome in VLBWIs are scarce. …”
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Molecular and cellular aspects of the impact of secondary metabolites from common barberry and hybrid goat’s rue on the HeLa cell line by E. Yu. Zlatnik, Ya. S. Enin, O. N. Burov, E. S. Bondarenko, A. B. Sagakyants, D. S. Kutilin, Yu. V. Dzigunova, O. G. Ishonina, E. V. Shalashnaya, N. D. Ushakova

“…The subsequent stage of the study demonstrated the maximal cellular death under the action of berberine at a 72-hour exposure. …”
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Long-term cardiovascular outcomes after percutaneous coronary intervention in patients with systemic sclerosis by Kazutoshi Hirose, Hiroyuki Kiriyama, Shun Minatsuki, Yugo Nagae, Tatsuki Furusawa, Takashi Hiruma, Atsushi Kobayashi, Masataka Sato, Shinnosuke Sawano, Tatsuya Kamon, Hiroki Shinohara, Mizuki Miura, Akihito Saito, Satoshi Kodera, Junichi Ishida, Norifumi Takeda, Hiroyuki Morita, Issei Komuro, Norihiko Takeda

“…The primary outcome was a composite of cardiac death, myocardial infarction, and stroke, and the secondary outcome was a composite of the primary outcome and heart failure hospitalization. …”
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Multidrug-Resistant <i>Acinetobacter baumannii</i>: Risk Factors for Mortality in a Tertiary Care Teaching Hospital by Kristina Černiauskienė, Astra Vitkauskienė

“…Patients with <i>A. baumannii</i> strains producing two different types of <i>β</i>-lactamases (AmpC plus KPC, AmpC plus ESBL, or ESBL plus KPC) stayed significantly shorter at the ICU compared to patients with <i>A. baumannii</i> strains with no detected <i>β</i>-lactamases (median of 9, IQR 2–18, vs. median of 26, IQR 7–38, <i>p</i> = 0.022). Death occurred in 58.7% (<i>n</i> = 115) of patients. …”
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Novel Role of Pin1-Cis P-Tau-ApoE Axis in the Pathogenesis of Preeclampsia and Its Connection with Dementia by Emmanuel Amabebe, Zheping Huang, Sukanta Jash, Balaji Krishnan, Shibin Cheng, Akitoshi Nakashima, Yitong Li, Zhixong Li, Ruizhi Wang, Ramkumar Menon, Xiao Zhen Zhou, Kun Ping Lu, Surendra Sharma

“…In the case of preE, proteinopathy/tauopathy may interrupt trophoblast differentiation and induce cell death, similar to the events occurring in neurons. …”
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