Management and outcomes of thoracic sarcomas - a collaboration between Orthopaedic Oncology and cardiothoracic surgery: seven-year clinical data from a tertiary referral centre by Zaid Ahmed Shamsi, Vlad Paraoan, Chang Kim, Sarah Raihanah Saifuddin, Thomas D A Cosker, Duncan Whitwell, Christopher L M H Gibbons, Dionisios Stavroulias, Francesco DiChiara

“…Results Of 113 identified cases, chondrosarcoma emerged as the most prevalent histological subtype among 22 distinct varieties. 58% of cases exhibited high-grade features. 32 sarcoma-related deaths occurred, with a mean time from diagnosis to death of 23.16 months. …”
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Exogenous dihomo-γ-linolenic acid triggers ferroptosis via ACSL4-mediated lipid metabolic reprogramming in acute myeloid leukemia cells by Xiandong Jiang, Yingying Huang, Xiaoying Hong, Wei Wu, Yanfeng Lin, Liping Lin, Yan Xue, Donghong Lin

“…Ferroptosis is a novel type of programmed cell death caused by excessive iron-dependent lipid peroxidation. …”
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Cuproptosis-Related Signature Predicts the Prognosis, Tumor Microenvironment, and Drug Sensitivity of Hepatocellular Carcinoma by Xiangjun Qi, Jiayun Guo, Guoming Chen, Caishan Fang, Leihao Hu, Jing Li, Chi Zhang

“…Cuproptosis is a novel format of cell death, and cuproptosis-related genes (CRGs) were identified. …”
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From Peril to Protection: an evaluation of regulations impacting eScooter injuries by Leslie M Kobayashi, Todd W Costantini, Jay J Doucet, Jarrett E Santorelli, Laura N Haines, Kendra M Black

“…There were three (0.8%) deaths. The median number of eScooter patients per month with prespeed limits was nine and post five (p=0.005), showing a 44.4% decrease in injured patients. …”
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Identification of Differentially Expressed Genes in Metastatic and Non-Metastatic Nasopharyngeal Carcinoma Cells by Suppression Subtractive Hybridization by Xu-Yu Yang, Cai-Ping Ren, Lei Wang, Hui Li, Chun-Jie Jiang, Hong-Bo Zhang, Ming Zhao, Kai-Tai Yao

“…Local recurrences and metastasis occur frequently in patients with NPC and are a leading cause of death, despite improvements on treatment modalities. …”
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Hydrogen Sulfide Promotes Functional Endometrium Recovery via Regulating Pyroptosis in Severe Endometrial Injury: A Prospective Laboratory Based Randomized Control Trial by Haiyan Shan, Mingyuan Xu, Jie Ni, Ling Zhou, Mengchun Xue, Jun Xue, Xiaohuan Yuan, Luyang Tao, Mingyang Zhang, Hong Zhang

“…Pyroptosis, a form of programmed cell death associated with inflammation, is initiated by the cleavage of gasdermin family proteins by caspase, which has been implicated in endometrial injury. …”
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Ddx21 mutant peptide is an effective neoantigen in prophylactic lung cancer vaccines and activates long-term anti-tumor immunity by Zhe Zhang, Yimeng Xia, Yimeng Xia, Zhihong Wang, Yaxing Sun, Dan Pu, Yijia He, Ruixian Liu, Yanru Zhang, Yan Liu, Junzhi Yu, Shiyang Ning, Baisui Feng, Yaohe Wang, Na Wang

“…IntroductionLung cancer is the leading cause of cancer-related death worldwide, and its morbidity and mortality are increasing. …”
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Modern options of endoscopic retrograde stenting of bile ducts in treatment of obstructive jaundice at malignant pancreatobiliary tumors by S. A. Budzinsky, S. G. Shapovalyants, Ye. D. Fedorov, A. G. Mylnikov, D. V. Bakhtiozina

“…Thus almost in all cases death occurred after achievement of endoscopic biliary decompression. …”
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Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study by Sylvia J. Kroese, Carolien N. H. Abheiden, Birgit S. Blomjous, Jacob M. van Laar, Ronald W. H. M. Derksen, Irene E. M. Bultink, Alexandre E. Voskuyl, A. Titia Lely, Marjon A. de Boer, Johanna I. P. de Vries, Ruth D. E. Fritsch-Stork

“…Severe hypertensive disorder of pregnancy, intrauterine fetal death, preterm birth, and small-for-gestational age infants occurred in 18.1%, 4.1%, 32.7%, and 14.8%, respectively. …”
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Legal regime of property registration: civil-legal aspect by Serdyuk R.

“…The need for legal certainty of the legal regime of inherited property from the moment of the testator’s death to the moment of its acceptance by the heir is substantiated. …”
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Predictive value of peripheral blood SNORD55 for prognosis of atrial fibrillation patients by WANG Yu, WANG Yu, WU Na, YANG Lanqing

“…In predicting the outcome of all-cause death and stroke， combination of the relative expression level of SNORD55 with CHA2DS2-VASc score increased both NRI ［54.3 （95%CI： 10.6~61.9） vs 31.9 （95%CI： 2.8~47.5）， P<0.05］ and IDI ［16.1 （95%CI： 2.4~27.0） vs 7.9 （95%CI： 0.5~14.8）， P<0.05］. …”
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Sulforaphane in alternative cancer chemotherapy: From carcinogenesis suppression to drug resistance reversal by Seyed Mohammad Doodmani, Payman Rahimzadeh, Najma Farahani, Seyedalireza Mirilavasani, Mina Alimohammadi, Noushin Nabavi, Elmira Alaei, Afshin Taheriazam, Maryam Abedi, Nadia Shafiee, Salman Daneshi, Mehrdad Hashemi

“…Key mechanisms discussed include the regulation of cell death pathways, such as apoptosis, ferroptosis, and autophagy, which are critical in cancer therapy. …”
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Rapid response electroencephalography decreases time to seizure diagnosis in pediatric acute care patients by Nevedha Rajan, Toni Kavanagh, Maite LaVega‐Talbott, Sandeep Gangadharan

“…Plain Language Summary Prolonged seizures in pediatric patients can cause death. Children can have seizures that are happening in the brain, but cannot be seen physically. …”
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The implementation and side effect management of immune checkpoint inhibitors in gynecologic oncology: a JAGO/NOGGO survey by Maximilian Riedel, Helene Herrmann, Thomas Bartl, Anna-Maria Rossner, Anna Tatzber, Chiara Flethe, Dario Zocholl, Barbara Schmalfeldt, Jalid Sehouli, Klaus Pietzner

“…A total of n = 16 (7.4%) reported at least one death of a patient due to irAEs. Feeling “unconfident” or “very unconfident” about managing irAEs was reported by 35.6% (n = 78). …”
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Root rot in medicinal plants: a review of extensive research progress by Yu Han, Yu Han, Tianqi Sun, Yuman Tang, Min Yang, Weiwei Gao, Lihong Wang, Chun Sui

“…Infected medicinal plants have shrivel or yellowed leaves, rotting rhizomes, and even death of the entire plant, resulting in a sharp decline in yield or even total crop failure, but also seriously reduce the commercial specifications and effective ingredient content of medicinal plants. …”
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Emergency Airway Management: A Systematic Review on the Effectiveness of Cognitive Aids in Improving Outcomes and Provider Performance by Raisa Chowdhury, Ostap Orishchak, Marco A. Mascarella, Bshair Aldriweesh, Mohammed K. Alnoury, Guillaume Bousquet-Dion, Jeffrey Yeung, Lily Ha-Nam P. Nguyen

“…Errors and delays in airway management can lead to adverse outcomes, including hypoxia and death. Cognitive aids, such as checklists and algorithms, have been proposed as tools to improve decision-making, procedural competency, and non-technical skills in these high-stakes environments. …”
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Impact of Arterial Remodeling of Intermediate Coronary Lesions on Long-Term Clinical Outcomes in Patients with Stable Coronary Artery Disease: An Intravascular Ultrasound Study by Liang Geng, Peizhao Du, Yuan Yuan, Liming Gao, Yunkai Wang, Jiming Li, Qi Zhang

“…The primary endpoint was the composite vessel-oriented clinical events, defined as the composition of target vessel-related cardiac death, target vessel-related myocardial infarction, and target vessel revascularization. …”
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Injectable supramolecular hydrogel co-loading abemaciclib/NLG919 for neoadjuvant immunotherapy of triple-negative breast cancer by Binyu Zhu, Ying Cai, Lingli Zhou, Lei Zhao, Jiameng Chen, Xiaoting Shan, Xujie Sun, Qian You, Xiang Gong, Wen Zhang, Helen He Zhu, Pengcheng Zhang, Yaping Li

“…The abemaciclib is able to induce immunogenic cell death of cancer cells and increase interleukin-2 secretion by cytotoxic T lymphocytes. …”
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Assessing anxiety symptoms and Traumatic Event Scale scores among medical staff during the COVID-19 pandemic in Colombia: a descriptive cohort study in Bogotá by Pablo Vásquez-Hoyos, Jhon Camacho-Cruz, Sara Marcela Torres Ayala, Susan Tatiana Cárdenas Rojas, Carolina Alexandra Zambrano Pérez, Juanita Yolanda Atuesta-Fajardo, Licet Villamizar-Gómez

“…Female gender (p=0.04), comorbidities (p=0.01), use of surgical gown (protective, p=0.01), perception of negative thoughts on the part of society (p=0.05), thoughts of wanting to give up or death (p&lt;0.001) and presenting some clinical level of traumatic event impact (p&lt;0.001) were associated with these anxiety symptoms. …”
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PET-Assessed Metabolic Tumor Volume Across the Spectrum of Solid-Organ Malignancies: A Review of the Literature by Anusha Agarwal, Chase J. Wehrle, Sangeeta Satish, Paresh Mahajan, Suneel Kamath, Shlomo Koyfman, Wen Wee Ma, Maureen Linganna, Jamak Modaresi Esfeh, Charles Miller, David C. H. Kwon, Andrea Schlegel, Federico Aucejo

“…Solid-organ malignancies represent a significant disease burden and remain one of the leading causes of death globally. In the past few decades, the rapid evolution of imaging modalities has shifted the paradigm towards image-based precision medicine, especially in the care of patients with solid-organ malignancies. …”
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