Youth experiencing homelessness at risk for suicide: psychosocial risk factors and service use patterns by Laura J. Chavez, Kelly J. Kelleher, Alicia Bunger, Xin Feng, Margaret Fitzpatrick, Jodi L. Ford, Allen B. Mallory, Arielle H. Sheftall, Tansel Yilmazer, Alexis Pizzulo, Jesse L. Hawke, Mattina A. Davenport, Natasha Slesnick

“…Abstract Objective Young adults experiencing homelessness often suffer from adverse mental health outcomes and suicide is a leading cause of death. The objective of this study is to examine service use and psychosocial risk factors for suicide, in relation to suicide risk assessment, to inform strategies for engaging youth in suicide prevention services. …”
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CDK4/6 inhibitors promote PARP1 degradation and synergize with PARP inhibitors in non-small cell lung cancer by Carlos M Roggero, Anwesha B Ghosh, Anvita Devineni, Shihong Ma, Eliot Blatt, Ganesh V. Raj, Yi Yin

“…This synergy correlates with increased accumulation of DNA damage, interrupted cell-cycle checkpoints, and enhanced apoptotic cell death. Mechanistically, we showed that CDK4/6is promote PARP1 protein degradation, which lead to decreased availability of DNA repair factors involved in homologous recombination and suppression of DNA repair competency. …”
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baran Luka Korban Kecelakaan Lalu Lintas yang Dilakukan Pemeriksaan di RSUP Dr. M. Djamil Padang by Isnu Lucky Riandini, Rika Susanti, Amel Yanis

“…It had been gotten 100 cases the victims of traffic accident for deaths and 73 cases for survivors at RSUP Dr. M. Djamil Padang. …”
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The influencing factors of the erythropoietin resistance index and its association with all-cause mortality in maintenance hemodialysis patients by Xinju Zhao, Liangying Gan, Fan Fan Hou, Xinling Liang, Xiaonong Chen, Yuqing Chen, Zhaohui Ni, Li Zuo

“…There were 176 (13.9%) deaths in total including 89 cardiac/vascular deaths during follow-up. …”
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Risk factors and machine learning prediction models for intrahepatic cholestasis of pregnancy by Yingchun Ren, Xiaoying Shan, Gengchao Ding, Ling Ai, Weiying Zhu, Ying Ding, Fuzhou Yu, Yun Chen, Beijiao Wu

“…Abstract Background Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that occurs in the second and third trimesters of pregnancy and is associated with a significant risk of fetal complications, including premature birth and fetal death. In clinical practice, the diagnosis of ICP is predominantly based on the presence of pruritus in pregnant women and elevated serum total bile acid. …”
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Long-term drought and risk of infant mortality in Africa: A cross-sectional study. by Pin Wang, Tormod Rogne, Joshua L Warren, Ernest O Asare, Robert A Akum, N'datchoh E Toure, Joseph S Ross, Kai Chen

“…The mean (standard deviation) number of months in which children experienced any drought during pregnancy and survival period (from birth through death before 1 year of age) was 4.6 (5.2) and 7.3 (7.4) among cases and non-cases, respectively. …”
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CAV1 promotes epithelial-to-mesenchymal transition (EMT) and chronic renal allograft interstitial fibrosis by activating the ferroptosis pathway by Qianguang Han, Bin Ni, Wei Bao, Junqi Zhang, Ming Zheng, Jinxu Miu, Zijie Wang, Jingwen Yuan, Jun Tao, Zhijian Han, Min Gu, Xiaobing Ju, Ruoyun Tan

“…Ferroptosis is an iron-dependent form of programmed cell death increasingly linked to chronic fibrosis. However, the mechanism by which ferroptosis contributes to the onset and progression of CAD remains unclear.MethodsThis study analyzed transcriptome data from renal transplant biopsy samples in the Gene Expression Omnibus (GEO), through clinical samples, animal models, and cell experiments, this study investigated the mechanism by which Caveolin-1 (CAV1) promotes CAD through the regulation of the ferroptosis pathway.ResultsThe elevated levels of CAV1 were found to positively correlate with CAD incidence. …”
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Diagnosis of lung cancer using salivary miRNAs expression and clinical characteristics by Negar Alizadeh, Hoda Zahedi, Maryam Koopaie, Mahnaz Fatahzadeh, Reza Mousavi, Sajad Kolahdooz

“…Abstract Objective Lung cancer (LC), the primary cause for cancer-related death globally is a diverse illness with various characteristics. …”
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Left Ventricular End-Systolic Volume Is a Reliable Predictor of New-Onset Heart Failure with Preserved Left Ventricular Ejection Fraction by Marina Kato, Shuichi Kitada, Yu Kawada, Kosuke Nakasuka, Shohei Kikuchi, Yoshihiro Seo, Nobuyuki Ohte

“…We screened the patients who received cardiac catheterization to evaluate coronary artery disease concomitantly with both left ventriculography and LV pressure recording using a catheter-tipped micromanometer and finally enrolled 355 patients with LVEF ≥ 50% and no history of heart failure (HF) after exclusion of the patients with severe coronary artery stenosis requiring early revascularization. Cardiovascular death or hospitalization for HF was defined as adverse events. …”
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Serum Cystatin C and Coronavirus Disease 2019: A Potential Inflammatory Biomarker in Predicting Critical Illness and Mortality for Adult Patients by Dan Chen, Wenwu Sun, Jia Li, Bohua Wei, Wei Liu, Xiaopin Wang, Fan Song, Liangkai Chen, Junhui Yang, Li Yu

“…In the adjusted logistic regression analyses, the highest cystatin C level and ln-transformed cystatin C levels were independently associated with the risks of developing critically ill COVID-19 and all-cause death either in overall patients or in patients without chronic kidney disease (P values < 0.05). …”
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Validation of the REDS score in hospitalised patients who deteriorated and were admitted to the intensive care unit—a retrospective cohort study by Narani Sivayoham, Oliver Mason, Harriet O’Mara, Natasha Trenchard Turner, Katie Sysum, Georgina Wicks

“…Background Hospitalised patients are at risk of deterioration and death. Delayed identification and transfer to the intensive care unit (ICU) are known to be associated with increased mortality rates. …”
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Determination of Total Levels of Secondary Metabolites and Oral Acute Toxicity Testing of Purple Leaf Ethanol Extract (PLEE) in Wistar Rats by Niluh Puspita Dewi, Miranti Miranti, Magfirah Magfirah, Athia Kurnia Kasim, I Made Dipayana

“…Conclusion: PLEE showed the highest total content of secondary metabolites in alkaloids, and consumption of PLEE in high doses caused the death of rats with a mild toxic classification.…”
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Spectrum, Pattern, and Clinical Outcomes of Adult Emergency Department Admissions in Selected Hospitals of Western Ethiopia: A Hospital-Based Prospective Study by Ashenafi Habte Woyessa, Birhanu Yadecha Dibaba, Getahun Fetensa Hirko, Thanasekaran Palanichamy

“…The healthcare delivery system of a country is required to be adjusted to patterns of morbidity and mortality to mitigate the minimized prolonged ill health consequences and premature death of adults. The spectrum, patterns, morbidity, and mortality of health and health-related emergency conditions for which patients visit hospitals often reflect the magnitude of different health problems in a society. …”
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Evaluation of a biomarker for amyotrophic lateral sclerosis derived from a hypomethylated DNA signature of human motor neurons by Calum Harvey, Alicja Nowak, Sai Zhang, Tobias Moll, Annika K Weimer, Aina Mogas Barcons, Cleide Dos Santos Souza, Laura Ferraiuolo, Kevin Kenna, Noah Zaitlen, Christa Caggiano, Pamela J Shaw, Michael P Snyder, Jonathan Mill, Eilis Hannon, Johnathan Cooper-Knock

“…Our work is relevant for all diseases featuring death of rare cell-types.…”
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Solo Sonographically Guided PCNL under Spinal Anesthesia: Defining Predictors of Success by Akbar Nouralizadeh, Hamid Pakmanesh, Abbas Basiri, Mohammad Aayanifard, Mohammad Hossein Soltani, Ali Tabibi, Farzaneh Sharifiaghdas, Seyed Amir Mohsen Ziaee, Naser Shakhssalim, Reza Valipour, Behzad Narouie, Mohammad Hadi Radfar

“…There was no cases of organ injury or death. Conclusion. Solo ultrasonographically guided PCNL under spinal anesthesia is feasible with an acceptable stone-free rate and complication rate.…”
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Antipsychotic prescribing practices and patient, family member and healthcare professional perceptions of antipsychotic prescribing in acute care settings: a scoping review protoco... by Zahinoor Ismail, Daniel Niven, Kirsten Fiest, Lisa Burry, Karla D Krewulak, Natalia Jaworska, Stephana Julia Moss, Zara Stelfox

“…Long-term use of antipsychotics is associated with increased risk of sudden cardiac death, falls and cognitive impairment. An understanding of acute care off-label antipsychotic prescribing practices and healthcare professional, patient and family perceptions related to antipsychotic prescribing and deprescribing is necessary to facilitate in-hospital deprescribing initiatives.Methods and analysis We present the protocol for a scoping review following the methodology proposed by Arksey and O’Malley and the Scoping Review Methods Manual by the Joanna Briggs Institute. …”
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Clinical Characteristics and Outcomes in Patients with Ruptured Middle Cerebral Artery Aneurysms: A Multicenter Study in Northern China by Xiuhu An, Jingliang Su, Bingxin Duan, Long Zhao, Bangyue Wang, Yan Zhao, Tianxing Li, Shuai Zhou, Xinyu Yang, Zhenbo Liu

“…The positive association between the risk of death and CT was consistent across subgroups. According to logistic regression, hypertension, previous stroke, combined ICH/IVH, Hunt and Hess grade, and WFNS (World Federation of Neurological Surgeons) score were identified as factors negatively influencing 2-year survival. …”
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Wheat Leaf Rust Effector Pt48115 Localized in the Chloroplasts and Suppressed Wheat Immunity by Lulu Song, Liping Cui, Hao Li, Na Zhang, Wenxiang Yang

“…Pt48115 inhibited cell death induced by Bcl-2-associated X protein (BAX) from mice or infestans 1 (INF1) from <i>Phytophthora infestans</i> in <i>Nicotiana benthamiana</i> and by DC3000 in wheat, and its 145–175 amino acids of the C-terminal are critical for its function. …”
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Factors Leading to Malnutrition in Children Under Five Years in Nyamwamba Division, Kasese Municipality, Kasese District. by Kabugho, Mary Consolata

“…Malnutrition is regarded as the most important risk factor for illness and death globally and it is associated with 52.5% 0f all deaths in young children (Lisanu Mazengia & Andargie Biks, 2018). …”
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Neural tube defects in a war-torn Tigray regional state of Ethiopia: a retrospective study of 54,626 deliveries by Birhane Alem Berihu, Afework Mulugeta, Tony Magana, Masresha Tessema, Tafere Gebreegziabher, Yibrah Berhe, Abadi Leul Welderufael, Hayelom Kebede Mekonen

“…Risk factors for NTDs include maternal age (20–29 years), rural residency, first pregnancies, a history of early neonatal death, lack of folic acid and multivitamin use, as well as neonatal factors like stillbirth, male sex, and preterm birth. …”
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