Enhancing Arabic text-to-speech synthesis for emotional expression in visually impaired individuals using the artificial hummingbird and hybrid deep learning model by Mahmoud M. Selim, Mohammed S. Assiri

“…Depression is one of the most dangerous mental health conditions, often leading to suicide, which is the fourth leading cause of death in the Middle East. Particularly, Egypt has the highest suicide rate in the region, making it crucial to recognize depression and suicidal thoughts early. …”
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BRCA1 is involved in sustaining rapid antler growth possibly via balancing of the p53/endoplasmic reticulum stress signaling pathway by Qianqian Guo, Zhen Wang, Jiping Li, Chao Ma, Junjun Zheng, Hengxing Ba, Guokun Zhang, Chunyi Li

“…Conclusions Our results revealed that BRCA1 is involved in sustaining rapid antler growth possibly via promotion of DNA damage repair that acts to maintain genome stability while protecting cells from p53/ERS-induced cell death. Understanding the mechanisms underlying the role played by BRCA1 in the process of antler regeneration is of great significance not only for regenerative medicine, but also for the understanding of cancer development.…”
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Lung-specific CRBN knockout attenuates influenza a virus-induced acute lung injury in mice: a potential therapeutic approach by Lifang Zhang, Qingchao Zhang, Jiahui Chang, Yunyi Zhou, Wei Wang, Xiliang Wang, Chengyu Jiang, Yanli Zhang

“…Knocking down CRBN in vitro significantly reduces PR8-induced cell death. Using Sftpc-Cre; Crbn flox/flox lung-specific Crbn knockout mice, we demonstrated that Crbn deficiency significantly decreased mortality, weight loss, lung pathology, edema, and viral load in PR8-infected mice. …”
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Harnessing natural polymers and nanoparticles: Synergistic scaffold design for improved wound healing by Anitha S, Nandini Robin Nadar, Srividya Shivakumar, Sharma S C, Siddharth P, Surekha Varalakshmi V, Rajesh Lenka, Rajadurai S

“…Skin injuries may be due to acute or chronic trauma, infections, and operations and can cause severe dysfunction or death. Hence, early clinical intervention becomes crucial in managing the problem. …”
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TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

“…Treatment with Elesclomol-Cu and 2DG significantly reduced the expression of the cuproptosis-related factor FDX1 with no impact on other cell death factors. Conclusion This study demonstrates that TWIST1 regulates the ubiquitination and degradation of HK2, thereby promoting glycolysis-induced cuproptosis and facilitating pancreatic cancer invasion and metastasis. …”
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A Lipiodol Pickering Emulsion Stabilized by Iron‐Doped Carbon Nanozymes for Liver Transarterial Chemoembolization by Xiancheng Xia, Yang Li, Rongkang Huang, Yuanbin Wang, Wenxuan Xiong, Hui Zhou, Min Li, Xidong Lin, Youchen Tang, Bo Zhang

“…More importantly, upon entry into tumor cells, ICN catalyze the generation of reactive oxygen species via the Fenton‐like reaction while simultaneously consuming intracellular glutathione, thereby inducing tumor cell death via chemodynamic therapy. By integrating chemotherapy and chemodynamic therapy, ICN‐LPE demonstrates a synergistic antitumor effect and effectively inhibits tumor growth in a rabbit liver tumor model. …”
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Oakland score to identify low-risk patients with lower gastrointestinal bleeding performs well among emergency department patients by Daniel D. DiLena, Sean C. Bouvet, Madeline J. Somers, Maqdooda A. Merchant, Theodore R. Levin, Adina S. Rauchwerger, Dana R. Sax

“…The Oakland Score composite outcome includes re-bleeding, defined as additional blood transfusion requirements and/or a further decrease in hematocrit (Hct) >/= 20% after 24 h in clinical stability; red blood cell transfusion; therapeutic intervention to control bleeding, including surgery, mesenteric embolization, or endoscopic hemostasis; in-hospital death, all cause; and re-admission with further LGIB within 28 days. …”
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Comprehensive Assessment of the Risk of Symptomatic Embolism in Patients With Infective Endocarditis by Sebastian D. Santos‐Patarroyo, Juan A. Quintero‐Martinez, Brian D. Lahr, Supavit Chesdachai, Daniel C. DeSimone, Hector R. Villarraga, Hector I. Michelena, Larry M. Baddour

“…Multivariable subdistribution hazards regression analysis was used to identify factors associated with the cumulative incidence of symptomatic embolism over 30 days accounting for the competing risk of death. Overall, 779 patients with IE were included, of whom 517 (66.4%) were men, median age was 65.0 (interquartile range, 52.9–74.8) years, and 89.3% were White. …”
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Pulmonary aspiration during pregnancy or immediately postpartum in the UK: A population-based case-control study [version 1; peer review: 2 approved] by Ruth Tunn, Marian Knight, Alison Gooda, Nuala Lucas

“…Background Pulmonary aspiration of gastric contents is the most frequent cause of death associated with complications of airway management during general anaesthesia. …”
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The causal relationship of cigarette smoking to metabolic disease risk and the possible mediating role of gut microbiota by Jingda Zhang, Lin Hou, Shanxiang Lei, Yan Li, Guogang Xu

“…Background: Cigarette smoking is a leading cause of preventable death worldwide, with its associated diseases and conditions. …”
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Oocyte transcriptomes and follicular fluid proteomics of ovine atretic follicles reveal the underlying mechanisms of oocyte degeneration by Yukun Song, Erhan Hai, Nan Zhang, Yu Zhang, Junlan Wang, Xitong Han, Jiaxin Zhang

“…Meanwhile, we also characterized unique features of the oocyte transcriptional landscape in the atretic follicle stage that displayed cell death-related transcriptional changes and mechanisms, such as autophagy (TBK1 and IRS4), necroptosis (PKR), and apoptosis (MARCKS). …”
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Structural Disruption of Cilia and Increased Cytoplasmic Tubulin in Biliary Atresia—An Exploratory Study Focusing on Early Postoperative Prognosis Following Portoenterostomy by Patrícia Quelhas, Rui Oliveira, Carlos Kieling, Sandra Vieira, Jorge dos Santos

“…Predictors of early poor prognosis (death or need for transplantation until 1 year of life) included HIF-1α positivity, elevated direct bilirubin levels, decreased cilia length, PC bending, and increased TUBA4A expression. …”
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Non-cancerous CT findings as predictors of survival outcome in advanced non-small cell lung cancer patients treated with first-generation EGFR-TKIs. by Pakorn Prakaikietikul, Pattraporn Tajarenmuang, Phumiphat Losuriya, Natee Ina, Thanika Ketpueak, Thanat Kanthawang

“…Large MPA size (>29 mm) or low total adiposity (≤85 cm2) alone predict 18-month death.…”
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ICU Admission, Invasive Mechanical Ventilation, and Mortality among Children and Adolescents Hospitalized for COVID-19 in a Private Healthcare System by Maria da Gloria Cruvinel Horta, Geraldo Jose Coelho Ribeiro, Nelson Otavio Beltrao Campos, Douglas Ribeiro de Oliveira, Lelia Maria de Almeida Carvalho, Karina de Castro Zocrato, Daniel Pitchon dos Reis, Mariana Ribeiro Fernandes, Ricardo Mesquita Camelo, Fernando Martin Biscione, Silvana Marcia Bruschi Kelles

“…The primary endpoint was the composite outcome consisting of ICU admission, need for invasive mechanical ventilation, or death. Results. We evaluated 199 patients who had an index hospitalization due to COVID-19. …”
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Адам и Ева как прообраз Нового Адама и Новой Евы (по учению святителя Иринея Лионского, Тертуллиана и святителя Викторина Петавийского). К вопросу о теории рекапитуляции в раннехри... by Nikolay A. Khandoga

“…As a result, instead of the death of Adam and Eve and their descendants (by bodily birth), humanity received immortality, starting with New Adam and New Eve and their descendants (by spiritual birth). …”
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CD56-Negative Aggressive NK Cell Leukemia Relapsing as Multiple Cranial Nerve Palsies: Case Report and Literature Review by M. Guerreiro, F. Príncipe, M. J. Teles, S. Fonseca, A. H. Santos, E. Fonseca, P. Gomes, C. Marques, M. Lima

“…Aggressive natural killer cell leukemia (ANKL) is extremely rare and habitually manifests as a systemic disease with multiorgan failure that rapidly evolves to death. The neoplastic natural killer (NK) cells usually harbor the Epstein-Barr virus (EBV) with a latent viral infection pattern type II; they often have a cytoplasmic CD3ε+ and surface CD3−, CD2+, and CD56+ immunophenotype, and they show complex genetic abnormalities affecting multiple tumor suppressor genes and oncogenes. …”
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Retrospective analysis of trauma patients transported by dispatch monitored type B ambulances to Dhulikhel Hospital, Kavre, Nepal, 2019–2023 by Maxwell L. Mantych, Shiva Neupane, Machchendra Sapkota, Laura D. Cassidy, Sarah C. Young, Ronald Anguzu, Samjhana Basnet

“…Abstract Background Timely emergency medical services (EMS) are particularly important among trauma patients, as inefficient EMS systems can result in potentially avoidable death before reaching a hospital. The Dhulikhel Hospital Dispatch Center coordinates and monitors a growing network of ambulances, including seven Type B ambulances staffed with a trained prehospital care provider and medical equipment. …”
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Impact of Obesity on Clinicopathologic Characteristics and Disease Prognosis in Pre- and Postmenopausal Breast Cancer Patients: A Retrospective Institutional Study by Nehad M. Ayoub, Rami J. Yaghan, Nour M. Abdo, Ismail I. Matalka, Laila M. Akhu-Zaheya, Alia H. Al-Mohtaseb

“…Multivariate logistic stepwise regression analysis was conducted to identify predictors for breast cancer recurrence and death. Results. Mean age at diagnosis was 50.98 ± 10.96 years. …”
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Global trends in the burden of ischemic heart disease based on the global burden of disease study 2021: the role of metabolic risk factors by Yifei Wang, Qing Li, Lei Bi, Bin Wang, Tingting Lv, Ping Zhang

“…Methods Data from GBD 2021 was analyzed to evaluate the global age-standardized death rates (ASDR) and disability-adjusted life years (ASRDALYs) linked to IHD. …”
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Comprehensive approach to predictive analysis and anomaly detection for road crash fatalities by Chopparapu Gowthami, S. Kavitha

“…Since traffic accidents are a major global cause of injury and death, it is essential to comprehend and reduce their effects. …”
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