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  1. 4401
  2. 4402

    Congenital Bullous Syphilis: A Case Report from Italy and a Comprehensive Literature Review by Edoardo Cammarata, Elia Esposto, Nunzia Di Cristo, Chiara Airoldi, Elena Bernascone, Valentina Burzio, Paola Savoia

    Published 2025-01-01
    “…Prompt recognition and diagnosis—enabled by diligent maternal screening, targeted neonatal testing, and careful clinical examination—are essential to initiate timely penicillin therapy and prevent severe complications or death. This review underscores the need for heightened clinical vigilance and adherence to established guidelines for syphilis screening and treatment during pregnancy, ultimately improving neonatal outcomes.…”
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  3. 4403

    Morphological and Chemical Changes in the Hemolymph of the Wax Moth <i>Galleria mellonella</i> Infected by the Entomopathogenic Fungus <i>Conidiobolus coronatus</i> by Mieczysława Irena Boguś, Agata Kaczmarek, Anna Katarzyna Wrońska, Mikołaj Drozdowski, Lena Siecińska, Ewelina Mokijewska, Marek Gołębiowski

    Published 2025-01-01
    “…In larvae with a high pathogen load, just before death, hemolymph volume decreased to nearly initial levels, while total protein content and synthesis (incorporation of <sup>35</sup>S-labeled methionine) increased. …”
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  4. 4404

    Efficacy of Larimichthys crocea TASOR protein-derived peptide FAM286 against Staphylococcus aureus by Ritian Jin, Guanglei Wei, Rong Lin, Wenfeng Lin, Jude Juventus Aweya, Duo Liang, Wuyin Weng, Shen Yang

    Published 2025-01-01
    “…FAM286 could also bind the bacterial DNA in an embedded manner, disrupting the structure of DNA and leading to the death of bacteria. This study comprehensively evaluated the antimicrobial mechanism of the FAM286 against S. aureus and provided a theoretical basis for the prevention and control of S. aureus.…”
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  5. 4405

    Maraviroc/cisplatin combination inhibits gastric cancer tumoroid growth and improves mice survival by Bárbara Mora-Lagos, María Elena Reyes, Lorena Lobos-Gonzalez, Matías del Campo, Kurt Buchegger, Louise Zanella, Ismael Riquelme, Carmen Gloria Ili, Priscilla Brebi

    Published 2025-01-01
    “…Abstract Background Gastric cancer (GC) is a significant cancer-related cause of death worldwide. GC’s most used chemotherapeutic regimen is based on platinum drugs such as cisplatin (CDDP). …”
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  6. 4406

    Increased Mortality from Extrapancreatic Infections in Hospitalized Patients with Acute Pancreatitis by Guido Grajales-Figueroa, Héctor Adrián Díaz Hernández, Martín Alejandro Chacón Portillo, Luis F. Uscanga, Mario Peláez-Luna, Jorge Hernández Calleros

    Published 2019-01-01
    “…For the case control study, the primary outcome evaluated was death, and to evaluate associated clinical features and determine differences between groups, we performed the χ2 or Fisher’s exact tests for categorical variables and the Student t-test or Mann-Whitney U test for continuous variables as appropriate. …”
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  7. 4407

    Adolescent HIV prevent and care framework: A global scoping review protocol- BSGH 006. by Gamji Rabiu Abu-Ba'are, Osman Wumpini Shamrock, Darcey Rodriguez, George Rudolph Kofi Agbemedu, LaRon E Nelson

    Published 2024-01-01
    “…Among adolescents, HIV/AIDs remains a significant cause of death globally [1-4]. Given the unique stages in human development, adolescents have been shown to fall within a sexually active phase. …”
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  8. 4408

    Gαs Protein Expression Is an Independent Predictor of Recurrence in Prostate Cancer by Lijuan Wang, Guihua Jin, Chenchen He, Xijing Guo, Xia Zhou, Meng Li, Xia Ying, Le Wang, Huili Wu, Qing Zhu

    Published 2014-01-01
    “…Gαs is an independent predictor to help determine the risk of PSA progression and death.…”
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  9. 4409
  10. 4410

    Assessment of stress hyperglycemia ratio to predict all-cause mortality in patients with critical cerebrovascular disease: a retrospective cohort study from the MIMIC-IV database by Yuwen Chen, Jian Xu, Fan He, An’an Huang, Jie Wang, Bingchen Liu, Qucheng Wei

    Published 2025-02-01
    “…Cox regression analysis revealed that SHR was independently associated with both in-hospital mortality (per standard deviation (SD) increase: hazard ratio (HR) 1.35, 95% confidence interval (CI) 1.23–1.48) and ICU mortality (per SD increase: HR 1.37, 95% CI 1.21–1.54). The risk of death increased in an approximately linear fashion when SHR exceeded 0.77–0.79. …”
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  11. 4411

    A Triple Obstetric Challenge of Thoracopagus-Type Conjoined Twins, Eclampsia, and Obstructed Labor: A Case Report from Sub-Saharan Africa by Mariatu Binta Leigh, Valerie John-Cole, Mike Kamara, Alimamy Philip Koroma, Michael Momoh Koroma, Edward Ejiro Emuveyan, Peter Bramlage, Ivo Buschmann

    Published 2017-01-01
    “…Clinical examination—ultrasound was not available—led to the admission diagnosis: obstructed labor with intrauterine fetal death and preeclampsia. Application of Hydralazine 5 mg (i.v.) under close blood pressure monitoring was performed. …”
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  12. 4412
  13. 4413

    Prevention of Cardiovascular Disease: Screening for Magnesium Deficiency by Paolo Severino, Lucrezia Netti, Marco Valerio Mariani, Annalisa Maraone, Andrea D’Amato, Rossana Scarpati, Fabio Infusino, Mariateresa Pucci, Carlo Lavalle, Viviana Maestrini, Massimo Mancone, Francesco Fedele

    Published 2019-01-01
    “…In fact, magnesium deficiency is involved in the pathophysiology of arterial hypertension, diabetes mellitus, dyslipidemia, metabolic syndrome, endothelial dysfunction, coronary artery disease, cardiac arrhythmias, and sudden cardiac death. In consideration of the great public-health impact of cardiovascular disease, the recognition of the negative effects of magnesium deficiency suggests the possible role of hypomagnesaemia as cardiovascular risk factor and the use of serum magnesium level for the screening and prevention of cardiovascular risk factors and cardiovascular diseases. …”
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  14. 4414

    A Longer Duration of Intravenous Antibiotic Treatment for Patients with Early Periprosthetic Joint Infections Is Not Associated with a Lower Failure Rate by Janneke Meijer, Alex Soriano, Wierd Zijlstra, Bas ten Have, Saad Tarabichi, Paul Jutte, Javad Parvizi, Marjan Wouthuyzen-Bakker

    Published 2025-01-01
    “…Failure was defined as the clinical need for (i) a second unintended DAIR procedure, (ii) implant removal, (iii) suppressive antibiotic treatment, or (iii) PJI-related death, all within one year after DAIR. Results: A total of 668 patients were included. …”
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  15. 4415

    Therapeutic potential of brentuximab vedotin in breast cancer and lymphoma via targeted apoptosis and gene regulation by Abeer Ezzat, Mohga Shafiek, Shimaa Shawki, Shaimaa Abdel-Ghany, Mahmoud Nazih, Hussein Sabit

    Published 2025-01-01
    “…Apoptosis detection confirmed Brentuximab-induced cell death, with significant increases in late apoptosis in cancer lines, especially by 72 h. …”
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  16. 4416

    Strategies to Lower In-Hospital Mortality in STEMI Patients with Primary PCI: Analysing Two Years Data from a High-Volume Interventional Centre by Alexandru Burlacu, Grigore Tinica, Igor Nedelciuc, Paul Simion, Bogdan Artene, Adrian Covic

    Published 2019-01-01
    “…Our analysis identified a predictive model for in-hospital mortality. The majority of deaths were due to cardiogenic shock. We suggested that in order to lower mortality under 5 percent, focus should be on creating a cardiogenic shock system based on the US experience. …”
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  17. 4417

    Utilization of a Joint Point Regression Model for Predicting Mortality Rates of Common Cancers in Babol City by Pouyan Ebrahimi, Sara Khaleghi, Mohebat Vali, Sahar Delavari, Soraya Khafri, Mohsen Karami, Layla Shojaie, Hossein‐Ali Nikbakht

    Published 2025-01-01
    “…Methods This cross‐sectional study considered all registered cancer‐related deaths from 2013 to 2021 in the Babol University of Medical Sciences' death registration and classification system. …”
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  18. 4418

    In silico comparative genomic analysis unravels a new candidate protein arsenal specifically associated with Fusarium oxysporum f. sp. albedinis pathogenesis by Hafida Ayada, Boutayna Dhioui, Hamid Mazouz, Abdelhay El harrak, Fatima Jaiti, Bouchra Ouhmidou, Mohammed Diouri, Mohieddine Moumni

    Published 2022-11-01
    “…The accessory protein SIX6, which induces plant cell death, was also predicted in Foa. Further analysis of secreted CAZymes revealed an arsenal of enzymes involved in plant cell wall degradation. …”
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  19. 4419

    Natremia Significantly Influences the Clinical Outcomes in Patients with Severe Traumatic Brain Injury by Bharti Sharma, Winston Jiang, Munirah M. Hasan, George Agriantonis, Navin D. Bhatia, Zahra Shafaee, Kate Twelker, Jennifer Whittington

    Published 2025-01-01
    “…Intensive care unit (ICU) admission, H discharge, and death also showed significance. A statistical difference was noted in ICU discharge levels while comparing blunt versus penetrating injury. …”
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  20. 4420

    Bioactivity and metabolic profiling of crude extracts from endophytic bacteria linked to Solanum mauritianum scope: Discovery of antibacterial and anticancer properties by Abraham Goodness Ogofure, Ezekiel Green

    Published 2025-01-01
    “…The cytotoxicity assays on UMG87 glioblastoma and A549 lung carcinoma cells revealed that the secondary metabolites did not induce cell death but instead promoted cell proliferation with different viability rates. …”
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