Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials by Alejandro Victoria-Escandell, José Santiago Ibañez-Cabellos, Sergio Bañuls-Sánchez de Cutanda, Ester Berenguer-Pascual, Jesús Beltrán-García, Eva García-López, Federico V. Pallardó, José Luis García-Giménez, Antonio Pallarés-Sabater, Ignacio Zarzosa-López, Manuel Monterde

“…Cell viability and cell death rate were assessed by flow cytometry. Oxidative stress was measured by OxyBlot. …”
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Single-cell transcriptomics of bronchoalveolar lavage during PRRSV infection with different virulence by Byeonghwi Lim, Seung-Chai Kim, Hwan-Ju Kim, Jae-Hwan Kim, Young-Jun Seo, Chiwoong Lim, Yejee Park, Sunirmal Sheet, Dahye Kim, Do-Hwan Lim, Kyeongsoon Park, Kyung-Tai Lee, Won-Il Kim, Jun-Mo Kim

“…Viral tracking reveals less than 5% of macrophages are directly infected, and further analysis indicates bystander cell death, likely regulated by exosomal microRNAs as a significant factor. …”
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Blocking the CD39/CD73 pathway synergizes with anti-CD20 bispecific antibody in nodal B-cell lymphoma by Carsten Müller-Tidow, Peter Dreger, Joseph Kauer, Wolfgang Huber, Clara Kolbe, Berit Brinkmann, Sascha Dietrich, Tobias Roider

“…We discovered that blockade of the CD39/CD73 pathway was particularly effective in patients with a high proportion of Programmed cell death protein 1 (PD-1)+ T-cell immunoglobulin and mucin-domain containing-3 (TIM3)+ exhausted T cells. …”
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The Health‐Related Quality of Life Impact of the COVID‐19 Pandemic on People Living with Multiple Sclerosis and the General Population: A Comparative Study Utilizing the EQ‐5D‐5L w... by Glen J. Henson, Ingrid van derMei, Bruce V. Taylor, Suzi B. Claflin, Andrew J. Palmer, Gang Chen, Julie A. Campbell

“…Health‐related quality of life was measured using health state utilities (HSUs; represented on a 0 [death] to 1 [full health] scale) generated by the EQ‐5D‐5L‐Psychosocial. …”
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Incidence and pathological features of IgA nephropathy before and during the COVID-19 pandemic by Wen Liu, Ricong Xu, Di Wu, Zhihang Su, Yuan Cheng, Haofei Hu, Xinzhou Zhang, Qijun Wan

“…Abstract IgA nephropathy (IgAN) imposes a substantial burden of illness and death. However, a systematic evaluation of the impact of the COVID-19 pandemic on the incidence and pathology of IgAN has yet to be performed. …”
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Final Analysis of Post‐Marketing Surveillance for Avelumab + Axitinib in Patients With Renal Cell Carcinoma in Japan by Norio Nonomura, Taito Ito, Masashi Sato, Makiko Morita, Mie Ogi, Masahiro Kajita, Mototsugu Oya

“…ABSTRACT Introduction Avelumab, an anti‐programmed death ligand 1 antibody, was approved in combination with axitinib for curatively unresectable or metastatic renal cell carcinoma (RCC) in Japan in December 2019. …”
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Non-Invasive Detection of Tumors by Volatile Organic Compounds in Urine by Tomoaki Hara, Sikun Meng, Yasuko Arao, Yoshiko Saito, Kana Inoue, Aya Hasan Alshammari, Hideyuki Hatakeyama, Eric di Luccio, Andrea Vecchione, Takaaki Hirotsu, Hideshi Ishii

“…Cancer is one of the major causes of death, and as it becomes more malignant, it becomes an intractable disease that is difficult to cure completely. …”
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Delayed PCI 12 Hours after the Onset of Symptoms Is Associated with Improved Outcomes for Patients with ST-Segment Elevation Myocardial Infarction: A Real-World Study by Wen-Juan Xiu, Hai-Tao Yang, Ying-Ying Zheng, Yi-Tong Ma, Xiang Xie

“…Propensity score matching (PSM) analyses remained significant differences between the delayed PCI group and the MT group, respectively, in all-cause deaths (9.3% versus 25.8%, P<0.001) and cardiac death (8.7% versus 21.6%, P<0.001). …”
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Impact of multimorbidity and complex multimorbidity on mortality among older Australians aged 45 years and over: a large population-based record linkage study by Alamgir Kabir, An Tran, Sameera Ansari, Damian P Conway, Margo Barr

“…However, little is known about the impacts of MM and CMM on mortality in Australia.Design Community-based prospective cohort study.Setting New South Wales, Australia.Participants People aged 45 years and over who completed the baseline survey of the 45 and Up Study.Measures Baseline survey data from the 45 and Up Study were linked with deaths registry data. Deaths that occurred within 8 years from the baseline survey date were the study outcome. …”
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Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm by U.P. Chernyaha-Royko, N.S. Pavlyk, M.S. Sorokivskyy, A.V. Aker, O.J. Zharinov

“…During 9-month follow-up, 15 (12.5 %) of 120 patients developed cardiovascular events: death (n = 1), stroke (n = 2), other thromboischemic events (n = 3), myocardial infarction (n = 1), decompensated heart failure (n = 4) and left ventricular ejection fraction (LVEF) reduction 10 % or more (n = 9). …”
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Cross-Cultural Adaptation and Validation of a Surgical Neonatal Nursing Workload Tool for an Italian Context: The Italian Winnipeg Surgical Complex Assessment of Neonatal Nursing N... by Emanuele Buccione, Floriana Pinto, Alessio Lo Cascio, Viola Palumbo, Kerry Hart, Allison Marchuk, Jessica-Lynn Walsh, Alexandra Howlett, The Italian Neonatal Nursing Workload Study Group, Laura Rasero, Davide Ausili, Stefano Bambi

“…Using an analysis of variance, we found that the higher the I-WANNNT-SC score was, the higher the predicted death rate (F = 13.05 and <i>p</i> < 0.001). <b>Conclusions:</b> The Italian Winnipeg Surgical Complex Assessment of Neonatal Nursing Needs Tool represents the first tool available for an Italian context that aims to measure the nursing workload in neonatal intensive care. …”
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Disulfidptosis-related gene SLC3A2: a novel prognostic biomarker in nasopharyngeal carcinoma and head and neck squamous cell carcinoma by Xinyi Zhang, Yiqi Lin, Liang Shi, Aixia Zhai, Chao Wu, Qian-Ying Zhu

“…Recently, disulfidoptosis, a novel form of cell death, has been proposed. Several studies in recent years have extensively investigated the function of the disulfidoptosis-related SLC7A11 gene in cancer, but the role of its partner protein, SLC3A2, remains unknown unclear in NPC.MethodsGEO database analysis confirmed SLC3A2's prognostic impact on nasopharyngeal carcinoma. …”
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自发性脑出血术后早期使用阿司匹林的可能性：来自中国学者的首个脑出血围手术期管理高级别循证依据 Possibility of Early Use of Aspirin after Spontaneous Intracerebral Hemorrhage Surgery: The First High-Level Evidence-Based Evidenc... by 周航，陈高(ZHOU Hang, CHEN Gao)

“…Abstract: Spontaneous intracerebral hemorrhage is one of the important diseases causing death and disability worldwide. Although surgical treatment has become increasingly mature, the corresponding postoperative management strategies remain poorly defined. …”
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Sustainability of Mahogany Production in Plantations: Does Resource Availability Influence Susceptibility of Young Mahogany Plantation Stands to Hypsipyla robusta Infestation? by C. B. Darko, E. Opuni-Frimpong, S. A. Owusu, B. Kyere, A. J. Storer

“…Attacks resulted in the death of the apical shoot and the proliferation of multiple shoots in only the Khaya spp., with K. ivorensis recording a lower number of shoots than K. grandifoliola. …”
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Risk of suicide in a sample of Egyptian high school adolescent students: a cross-sectional study by Eman S. Rabie, Marwa Soltan, Hanan Elrassas, Atteya Khairy, Moatazbellah I. Ali

“…In late childhood and early adulthood, it is one of the primary triggers of death. Negative social and economic consequences and negative psychological consequences have been linked to it. …”
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Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via A... by Xuan Tian, Huan Cao, Longlong Wu, Weiping Zheng, Mengshu Yuan, Xiang Li, Hongli Song, Zhongyang Shen

“…Livers from donors after circulatory death (DCD) are inevitably exposed to a longer warm ischemic period, which might increase the incidence of postoperative bile duct complications. …”
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Five lessons from a mid-level health manager intervention to increase uptake of tuberculosis prevention therapy in Uganda: ‘it is a completely different thing to implement what you... by Jason Johnson-Peretz, Canice Christian, Cecilia Akatukwasa, Fred Atwine, Elijah Kakande, Moses R. Kamya, Diane V. Havlir, Carol S. Camlin, Gabriel Chamie

“…IPT is known to reduce active tuberculosis (TB), a leading cause of death among PLHIV, by 40–60%. Methods We performed a thematic analysis of six focus-group discussions from this intervention (held in May 2019, January 2020, September 2021) and 23 key informant interviews with control group participants (between February and August 2019 and September and December 2020). …”
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Bright night sleeping environment induces diabetes and impaired glucose tolerance in non-human primates by Shuxing Wang, Zhenyi Chen, Zihao Liang, Qiang Xu, Jiankai Zhang

“…Data pertaining to the glucose metabolism such as concentrations of fasting glucose, glycosylated hemoglobin, plasma insulin and C-peptide were collected monthly and analyzed.Results1) Bright night exasperated glucose metabolism in individuals with pre-existing diabetes, led to premature death; 2) Stronger white light intensity-dependently induced diabetes and IFG in previous healthy monkeys: the brighter the light, the quicker the metabolism disturbance and IFG developed, and also the higher morbidity of LID and IFG; 3) Exposure to nocturnal light had a synergistic impairing effect on glucose metabolism with aging and weight. 4) Female were more susceptible to night brightness.ConclusionsLight in sleeping environment exacerbates glucose metabolism in individuals with pre-existing diabetes, leads to IFG and diabetes in healthy primates. …”
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Incidence and predictors of mortality among HIV positive children on anti-retroviral therapy in the selected health facilities of West Wollega Zone, Western Ethiopia: Retrospective... by Gelane Gurmu, Emiru Merdassa, Gemechu Tiruneh, Keneni Efrem, Firezer Belay, Lalisa Mekonnen, Jira Wakoya Feyisa, Matiyos Lema, Adisu Tafari Shama, Markos Desalegn

“…<h4>Results</h4>The total follow-up time was 15, 652 child-months, and the overall incidence of mortality was 1.92 (95%CI: 1.34, 2.74) per 1000 child-months. The median time to death following the initiation of ART was 6 months. …”
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Bidirectional approach of Punica granatum natural compounds: reduction in lung cancer and SARS-CoV-2 propagation by Md. Abul Barkat, Afreen Fatima, Bushra Riaz, Mohd. Zaheen Hassan, Tanveer Ahamad, Abdulkareem A. Alanezi, Harshita Barkat, Afaf F. Almuqati, Yahya I. Asiri, Sahabjada Siddiqui

“…PGP has shown a potential to reduce lung cancer cell proliferation while evading normal cell death. PGP induced apoptosis by arresting cells in the G0/G1 phase and generating ROS. …”
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