Deep Vein Thrombosis and Pulmonary Embolism Secondary to Thrombophilic Disorder: A Case Report by Satbir Kaur Malik, Vineetha Naga Lakshmi Giduturi, Sindhuri Goud Nimmala, Vijayashree Gokhale

“…Deep Vein Thrombosis (DVT) is a common condition that is part of venous thromboembolism disorders and represents the third most common cause of death from cardiovascular disease, following heart attacks and strokes. …”
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Effect of decitabine on PD-L2 methylation in whole blood of iodine-induced autoimmune thyroiditis rats by Baiming Jin, Yanbo Qi, Hong Chao, Xiaolei Yang, Hongjie Li, Siyuan Wan

“…Excessive iodine intake can induce autoimmune thyroiditis (AIT), and the methylation of programmed death receptor 2 (PD-L2) may be involved in the development of iodine-induced AIT. …”
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Synthesis of Water-Soluble Iridium (III)-Containing Nanoparticles for Biological Applications by Huanzhi Hou, Pengfei Sun, Quli Fan, Xiaomei Lu, Cheng Xue, Yixue Zhang, Sichao Tian, Wei Huang

“…Ir/PGlc-NP and Ir/β-1,3-glucan-NP showed the same emission maxima at 565 nm in aqueous solution and both caused effective apoptosis and death of HepG2 and Hela cells after being irradiated at 445 nm for 30 min in vitro. …”
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Prioritization of biological processes based on the reconstruction and analysis of associative gene networks describing the response of plants to adverse environmental factors by P. S. Demenkov, E. A. Oshchepkova, T. V. Ivanisenko, V. A. Ivanisenko

“…The prioritization results indicate that fundamental processes, such as gene expression, post-translational modifications, protein degradation, programmed cell death, photosynthesis, signal transmission and stress response play important roles in the common molecular genetic mechanisms for plant response to various adverse factors. …”
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Trends, gender, and racial disparities in patients with mortality due to paroxysmal tachycardia: A nationwide analysis from 1999-2020. by Aman Goyal, Humza Saeed, Saif Yamin, Abdullah, Wania Sultan, Muhammad Khubaib Arshad, Samia Aziz Sulaiman, Mah I Kan Changez, Gauranga Mahalwar

“…<h4>Methods</h4>Our study examined death certificates from 1999 to 2020 using the CDC WONDER Database to identify deaths caused by paroxysmal tachycardia in individuals aged 25 and older, using the ICD-10 code I47. …”
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Pharmacological Characterization of the Mechanisms Involved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone by Sergio Perez-Alvarez, Maria E. Solesio, Maria D. Cuenca-Lopez, Raquel M. Melero-Fernández de Mera, Carlos Villalobos, Hanna Kmita, Maria F. Galindo, Joaquin Jordán

“…Previously, we have shown that SH-SY5Y cells exposed to high concentrations of methadone died due to a necrotic-like cell death mechanism related to delayed calcium deregulation (DCD). …”
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Thresholds of handgrip strength for all-cause mortality in patients with chronic kidney disease: a secondary systematic review with dose-response meta-analysis by Hao Chen, Fan Zhang, Liuyan Huang, Yan Bai, Yifei Zhong, Yi Li

“…After that, the risk of death increased slightly.Conclusion A U-shaped association exists between handgrip strength and all-cause mortality risk in CKD patients. …”
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Long-Term (10-Year) Gastrointestinal and Genitourinary Toxicity after Treatment with External Beam Radiotherapy, Radical Prostatectomy, or Brachytherapy for Prostate Cancer by Grant K. Hunter, Chandana A. Reddy, Eric A. Klein, Patrick Kupelian, Kenneth Angermeier, James Ulchaker, Nabil Chehade, Andrew Altman, Jay P. Ciezki

“…Due to the low event rate for late GU and GI toxicities, a competing risk regression (CRR) analysis was done with death as the competing event. Results. Median follow-up time was 8.5 years. …”
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Delayed Postoperative Ambulation Results in a Significant Increase in 90-Day Mortality in Surgically Treated Hip Fractures by Robert S. Wood DO, Maddie Vergun BS, Elizabeth Herrera MPH, Jacqueline Krumrey MD

“…Logistic regression indicated that the odds of death were 17 times higher in patients who did not walk during their hospital stay (OR: 17.0, 95% CI: 2.91-326.0, P -value: 0.01). …”
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Association of Race and Major Adverse Cardiac Events (MACE): The Atherosclerosis Risk in Communities (ARIC) Cohort by Ericha G Franey, Donna Kritz-Silverstein, Erin L Richard, John E Alcaraz, Caroline M Nievergelt, Richard A Shaffer, Vibha Bhatnagar

“…MACE was defined as first occurrence of myocardial infarction, stroke, or CHD-related death through 2004. Cox proportional hazards regression was used to evaluate the association between race and MACE after adjustment for age, gender, and other demographic and cardiovascular risk factors such as diabetes and hypertension. …”
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Awake thoracic surgery for lung cancer treatment: where we are and future perspectives—our experience and review of literature by Giovanni Mugnaini, Simone Tombelli, Antonio Burlone, Stefano Bongiolatti, Domenico Viggiano, Rossella Indino, Ottavia Salimbene, Lavinia Gatteschi, Luca Voltolini, Alessandro Gonfiotti

“…Abstract Background Lung cancer is the first cause of cancer-related death. Awake lung resection is a new frontier of the concept of minimally invasive surgery. …”
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Transcatheter edge to edge compared with surgery in older patients with degenerative mitral valve regurgitation by Gaspard Suc, Rebecca Hadjedj, Jules Mesnier, Skerdi Haviari, Marylou Para, Gregory Ducrocq, Dominique Himbert, Eric Brochet, My Lien Nguyen, Sophie Provenchere, Marina Urena, Bernard Iung

“…Primary outcome was a composite of all-cause death, hospitalization for heart failure or mitral valve intervention within one year. …”
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The Effects of Extra Virgin Olive Oil on Alanine Aminotransferase, Aspartate Aminotransferase, and Ultrasonographic Indices of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease... by Farzad Shidfar, Samaneh Sadat Bahrololumi, Saeid Doaei, Assieh Mohammadzadeh, Maryam Gholamalizadeh, Ali Mohammadimanesh

“…Coronary artery disease is the most common cause of death in the patients with nonalcoholic fatty liver disease (NAFLD). …”
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Study on the Mechanism of Black Phosphorus Nanosheets Loading Sr2+ Used in Photothermal Antibacterial Treatment by Ma G, Li B, Diao J, Zhang Y, Zhang B, Wu D, Gui H, Zhong J, Zhu H, Zhang D

“…Finally, the transcriptomic results suggest that bacteria death may be related to membrane destruction, metabolic disorders, and transport damage. …”
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Delta-opioid receptor signaling alleviates neuropathology and cognitive impairment in the mouse model of Alzheimer’s disease by regulating microglia homeostasis and inhibiting HMGB... by Yuan Xu, Naiyuan Shao, Feng Zhi, Ronghua Chen, Yilin Yang, Jiahui Li, Ying Xia, Ya Peng

“…Methods We compared the delta-opioid receptor (DOR)- and mu-opioid receptor (MOR)-mediated effects on AD-associated cognitive deficits, pathologies, neuroinflammations, cell death using transgenic APP/PS1 mouse model and BV2 cell line at behavioral, molecular, and cellular levels. …”
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Effect of Hydroxychloroquine and Azithromycin on QT Interval Prolongation and Other Cardiac Arrhythmias in COVID-19 Confirmed Patients by Seyed Parsa Eftekhar, Sohrab Kazemi, Mohammad Barary, Mostafa Javanian, Soheil Ebrahimpour, Naghmeh Ziaei

“…They can prolong QT interval, cause torsade de pointes, and lead to sudden cardiac death. We aimed to assess QT interval prolongation and its risk factors in patients who received hydroxychloroquine with or without azithromycin. …”
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Effect and safety of ethanolamine oleate in sclerotherapy in patients with difficult-to-resect venous malformations: A multicenter, single-arm study. by Mine Ozaki, Tadashi Nomura, Keigo Osuga, Masakazu Kurita, Ayato Hayashi, Shunsuke Yuzuriha, Noriko Aramaki-Hattori, Makoto Hikosaka, Taiki Nozaki, Michio Ozeki, Junko Ochi, Shimpei Akiyama, Yasumasa Kakei, Keiko Miyakoda, Naoko Kashiwagi, Takahiro Yasuda, Yuki Iwashina, Tsuyoshi Kaneko, Kiyoko Kamibeppu, Takafumi Soejima, Kiyonori Harii

“…Both cohorts showed significant improvement in self-reported pain scores associated with lesions 3 months post-sclerotherapy. No death or serious adverse events occurred. Hemoglobinuria was observed in 23 patients (52%), a known drug-related adverse event. …”
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Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids by Julie Bejoy, Xuegang Yuan, Liqing Song, Thien Hua, Richard Jeske, Sébastien Sart, Qing-Xiang Amy Sang, Yan Li

“…In addition, the metabolic pathways and the signaling pathways involved in cell proliferation, cell death, PIK3/AKT/mTOR signaling, eukaryotic initiation factor 2 pathway, and Wnt and Notch pathways were analyzed. …”
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Clinical Outcome Discrimination in Pediatric ARDS by Chest Radiograph Severity Scoring by Yu-Chun Yan, Wen-Han Hao, Feng-Sen Bai, Shuang Liu, Dong Qu, Xin-Yu Yuan

“…Subgroups were compared by prognosis (survive and death) and etiology (infection and noninfection). …”
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Recent approaches in the drug research and development of novel antimalarial drugs with new targets by Chinnappanna Naveen Kumar Reddy, Yennam Gopi, Chaitanya Chaitanya Budagam Haima Naga Venkata, Pottathil Shinu, Borah Pobitra, Venugopala Katharigatta N., Deb Pran Kishore, Mailavaram Raghu Prasad

“…Malaria is a serious worldwide medical issue that results in substantial annual death and morbidity. The availability of treatment alternatives is limited, and the rise of resistant parasite types has posed a significant challenge to malaria treatment. …”
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