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  1. 4001

    Effects of Muse Cell on a Mouse Model With Acute Encephalopathy by Tatsuya Kawaguchi, Tetsuji Mori, Kaori Adachi, Jun Fujii, Yoshihiro Maegaki, Fumiko Obata

    Published 2025-01-01
    “…ABSTRACT Introduction Acute encephalopathy (AE) in childhood due to a viral infection causes convulsions and altered consciousness, leading to severe sequelae and death. Among the four types of AE, cytokine storm–induced AE is the most severe and causes serious damage to the brain. …”
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  2. 4002

    The functional insight into the genetics of cardiovascular disease: results from the post-GWAS study by L. O. Bryzgalov, E. E. Korbolina, I. S. Damarov, T. I. Merkulova

    Published 2022-03-01
    “…Cardiovascular diseases (CVDs), the leading cause of death worldwide, generally refer to a range of pathological conditions with the involvement of the heart and the blood vessels. …”
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  3. 4003

    Acute Oral Toxicity, Histopathological Analysis, and Antimalarial Potential of Jatropha tanjorensis Leaf Extracts by Fatima Jumare, Helen Ileigo Inabo, Muhammad Hassan Isa Doko, Gbonjubola Olusesan Adeshina

    Published 2024-12-01
    “…Data analysis was conducted using GraphPad Prism version 9.3.1.Results: The experimental mice exposed to J. tanjorensis leaf extracts exhibited no symptoms of toxicity, although one death was recorded across two groups. According to OECD guidelines, with fewer than three deaths observed, the LD50 of J. tanjorensis leaf extracts is estimated to exceed 5000 mg/kg body weight, indicating a high safety margin. …”
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  4. 4004

    Dimethoate Induced Behavioural Changes in Juveniles of Cyprinus carpio var. communis under Temperate Conditions of Kashmir, India by Imtiyaz Qayoom, Feroz A. Shah, Malik Mukhtar, Masood H. Balkhi, Farooz A. Bhat, Bilal A. Bhat

    Published 2016-01-01
    “…The fishes elicited various behavioural responses such as uncoordinated movements, convulsions, excessive mucus secretion, and imbalanced swimming which ended in a collapse to the bottom of the aquarium. Prior to death, the clinical signs like scale erosion, pale body colour, and hemorrhagic patches over the body were noticed which became more vivid up to the termination of experiments. …”
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  5. 4005

    Validation of mortality risk scores after esophagectomy by Sabine Schiefer, Nerma Crnovrsanin, Ingmar F. Rompen, Nicolas Jorek, Mohammed Al-Saeedi, Thomas Schmidt, Henrik Nienhüser, Leila Sisic

    Published 2025-01-01
    “…Various scoring systems exist to identify patients at high risk for postoperative complications and death. In the following, we aim to evaluate and compare these different scoring systems. …”
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  6. 4006

    Papillary Carcinoma of Breast: Clinicopathological Characteristics, Management, and Survival by Bushra Rehman, Anam Mumtaz, Barka Sajjad, Namra Urooj, Sameen Mohtasham Khan, M. Toqeer Zahid, Huma Mannan, M. Zulqarnain Chaudhary, Amina Khan, M. Asad Parvaiz

    Published 2022-01-01
    “…Only 2 patients had bone metastasis (one was IPC and one EPC). Cancer-related death was observed in 3 patients. For all groups combined, 5-year OS was 98% and DFS was 92%. …”
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  7. 4007

    A Machine Learning Based Framework for a Stage-Wise Classification of Date Palm White Scale Disease by Abdelaaziz Hessane, Ahmed El Youssefi, Yousef Farhaoui, Badraddine Aghoutane, Fatima Amounas

    Published 2023-09-01
    “…When an infestation reaches a specific degree, it might result in the tree’s death. To counter this threat, precise detection of infected leaves and its infestation degree is important to decide if chemical treatment is necessary. …”
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  8. 4008

    Characteristic Fe and Cu Compounds in Particulate Matter from Subway Premises in Japan and their Potential Biological Effects by Takuma Okamoto, Ayumi Iwata, Hiroko Yamanaka, Kako Ogane, Tatsuhiro Mori, Akiko Honda, Hirohisa Takano, Tomoaki Okuda

    Published 2024-12-01
    “…In contrast to typical bivalent Cu compounds in the atmosphere, monovalent Cu compounds, which are characteristically identified in subway PM, exacerbate cell damage via different cell death pathways. Our results indicate that the chemical states of the distinctive compounds in the PM of subway premises differ from those in the typical atmosphere, thus exerting different biological effects. …”
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  9. 4009

    The Therapeutic Targets of miRNA in Hepatic Cancer Stem Cells by Sabrina Bimonte, Maddalena Leongito, Antonio Barbieri, Vitale del Vecchio, Michela Falco, Aldo Giudice, Raffaele Palaia, Vittorio Albino, Raimondo Di Giacomo, Antonella Petrillo, Vincenza Granata, Francesco Izzo

    Published 2016-01-01
    “…Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide malignancy and the third leading cause of cancer death in patients. Several studies demonstrated that hepatic cancer stem cells (HCSCs), also called tumor-initiating cells, are involved in regulation of HCC initiation, tumor progression, metastasis development, and drug resistance. …”
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  10. 4010

    Etiology of Emergency Visit and In-Hospital Outcomes of Patients with COPD by Xueyang Zhang, Qingtao Zhou, Shengfeng Wang, Qingbian Ma, Yongchang Sun

    Published 2022-01-01
    “…The primary diagnosis at discharge or death was recorded. The hospitalization settings (general wards and ICU), the in-hospital outcomes, and associated factors were analyzed. …”
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  11. 4011

    Knowledge about Danger Signs of Obstetric Complications and Associated Factors among Postnatal Mothers of Mechekel District Health Centers, East Gojjam Zone, Northwest Ethiopia, 20... by Gedefa Amenu, Zerfu Mulaw, Tewodros Seyoum, Hinsermu Bayu

    Published 2016-01-01
    “…Women awareness of obstetric danger sign to recognize complications to seek medical care early is the first intervention in an effort to decrease maternal death. Objective. To assess knowledge about danger signs of obstetric complications and associated factors among postnatal mothers at Mechekel district health centers, East Gojjam zone, Northwest Ethiopia, 2014. …”
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  12. 4012

    Mitochondrial Mayhem: How cigarette smoke induces placental dysfunction through MMS19 degradation by Pei Zhou, Feng Jin, Shenshen Yao, Ben Sun, Ni Sun, Hongbo Guan, Xiaomei Liu

    Published 2025-01-01
    “…This study aims to investigate the impact of CS on trophoblast cell proliferation and regulated cell death (RCD) by examining its interference with iron-sulfur cluster (ISC) proteins and the CIA pathway. …”
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  13. 4013

    Hypochloraemia and 30 day readmission rate in patients with acute decompensated heart failure by Roman Marchenko, Adam Sigal, Thomas E. Wasser, Jessica Reyer, Jared Green, Christopher Mercogliano, Muhammad Sohail Khan, Anthony A. Donato

    Published 2020-06-01
    “…Hypochloraemia (either on admission or at discharge) was identified in 289 patients (23.3%) and was associated with significantly higher 30 day hospital readmission rate or death (42.2% vs. 33.7%, P = 0.008). This association persisted in multivariate analysis when controlling for serum sodium, weight loss, diuretic dose, adjunct thiazide use, serum blood urea nitrogen, and BNP levels (OR: 1.35, 95% CI: 1.02–1.77, P = 0.033); however, the predictive value of the overall model was low (Naglkerke R2 = 0.040). …”
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  14. 4014

    Therapeutic Potential of <i>Lappula patula</i> Extracts on Germline Development and DNA Damage Responses in <i>C. elegans</i> by Qinghao Meng, Anna Hu, Weiyu Xiao, Robert P. Borris, Hyun-Min Kim

    Published 2025-01-01
    “…Apoptosis was quantified by monitoring cell death during the pachytene stage. LC-MS was used to identify bioactive compounds within the extracts. …”
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  15. 4015

    Variation in clinical and patient‐reported outcomes among complex heart failure with preserved ejection fraction phenotypes by Kelsey M. Flint, Sanjiv J. Shah, Eldrin F. Lewis, David P. Kao

    Published 2020-06-01
    “…Rate of the TOPCAT primary outcome (cardiovascular death, aborted cardiac arrest, or heart failure hospitalization) differed by HFpEF phenotype (P < 0.001) but not by treatment arm within each HFpEF phenotype. …”
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  16. 4016

    Impact of Comorbidities on the Severity of Disease & Outcome in Children with COVID 19 at a Tertiary Care Pediatric Hospital, Rawalpindi. by Rai Muhammad Asghar, Muddassar Sharif, Khalid Saheel, Isfandyar Khan, Abid Hussain, Rai Rijjal Ashraf

    Published 2023-06-01
    “…It is considered that COVID-19, in those with underlying health conditions or co-morbidities, has an increasingly rapid and severe progression, often leading to death. This study is designed to evaluate the impact of co-morbidities on the severity and outcome of COVID-19 infection in children. …”
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  17. 4017

    Early referral to nephrological care improves long-term survival and hospitalization after dialysis initiation, independent of optimal dialysis start – a call for harmonization of... by Mathias Haarhaus, Lavinia O. Bratescu, Nicolae Pana, Emanuela M. Gemene, Eliana M. Silva, Carla Alexandra R. Santos Araujo, Fernando Macario

    Published 2024-12-01
    “…The observational period was truncated at 3 years, death, or loss to follow-up. Clinical and laboratory data were retrieved from the quality database of the nephrological care providers. …”
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  18. 4018

    Lethal Male Combat of <i>Anastatus japonicus</i> (Hymenoptera: Eupelmidae), an Egg Parasitoid of Lepidopterous and Hemipterous Pests by Muhammad Yasir Ali, Gonzalo A. Avila, Zheng-Yu Luo, Muhammad Asghar Hassan, Khalid Ali Khan, Jin-Ping Zhang, Feng Zhang

    Published 2025-01-01
    “…Aggressive interactions between males are common when victors gain increased mating success but can result in severe injury or death for the defeated. <i>Anastatus japonicus</i> (Hymenoptera: Eupelmidae) is a solitary egg parasitoid of hemipteran and lepidopteran species. …”
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  19. 4019

    Integrated microRNA and mRNA signatures associated with overall survival in epithelial ovarian cancer. by Joanna Lopacinska-Jørgensen, Douglas V N P Oliveira, Guy Wayne Novotny, Claus K Høgdall, Estrid V Høgdall

    Published 2021-01-01
    “…Ovarian cancer (OC), the eighth-leading cause of cancer-related death among females worldwide, is mainly represented by epithelial OC (EOC) that can be further subdivided into four subtypes: serous (75%), endometrioid (10%), clear cell (10%), and mucinous (3%). …”
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  20. 4020

    A retrospective analysis of the malaria trend in Yemen over the sixteen-years, from 2006 to 2021 by Wadhah Hassan Edrees, Wadee Abdullah Al-Shehari

    Published 2025-01-01
    “…Yemen reported 704 (0.02%) malaria death cases with an overall rate of case fatality of 0.03% and a mortality rate of 0.18 per 100,000 populations. …”
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