NT-proBNP and Major Adverse Cardiovascular Events in Patients with ST-Segment Elevation Myocardial Infarction Who Received Primary Percutaneous Coronary Intervention: A Prospective... by Zuoan Qin, Yaoyao Du, Quan Zhou, Xuelin Lu, Li Luo, Zhixiang Zhang, Ning Guo, Liangqing Ge

“…Stent thrombosis, reinfarction, congestive heart failure, unstable angina, and cardiac death were considered as MACEs in this study. The target-independent and -dependent variables were NT-proBNP at baseline and MACE, respectively. …”
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In Vitro Evaluation of a Stable Monomeric Gold(II) Complex with Hematoporphyrin IX: Cytotoxicity against Tumor and Kidney Cells, Cellular Accumulation, and Induction of Apoptosis by Georgi Momekov, Dilyan Ferdinandov, Spiro Konstantinov, Sonja Arpadjan, Daniela Tsekova, Galina Gencheva, Panayot R. Bontchev, Margarita Karaivanova

“…The gold complex induces oligonucleosomal DNA fragmentation in tumour cells following 24-hour treatment and hence its cytotoxic effect is at least partly mediated by induction of apoptotic cell death. A prominent intracellular gold accumulation was detected after treating tumor cells with [Au(II)Hp-2H.…”
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Cost-Effectiveness of the CNIC-Polypill Strategy Compared With Separate Monocomponents in Secondary Prevention of Cardiovascular and Cerebrovascular Disease in Portugal: The MERCUR... by Carlos Aguiar, Francisco Araujo, Gabriel Rubio-Mercade, David Carcedo, Silvia Paz, Jose María Castellano, Valentín Fuster

“…**Background:** Cardiovascular (CV) diseases remain a leading and costly cause of death globally. Patients with previous CV events are at high risk of recurrence. …”
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Genetic polymorphisms and related risk factors of ischemic stroke in a Mongolian population in China by Q. Wu, H. Wu, Yu. L. Orlov, G. Gegentana, W. Huo, A. O. Bragin, N. Wu, S. Suyalatu, F. Zhao, J. Zhao, L. E. Tabikhanova, M. Chen, H. Bai

“…Ischemic stroke is caused by an interruption in the flow of blood to the brain and a risk factor for death and disability. Recent genome-wide association studies have identified more than 40 common sequence variants associated with ischemic stroke. …”
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Exploration of the molecular mechanism behind a novel natural genic male-sterile mutation of 1205A in Brassica napus by Lijing Xiao, Jinze Zhang, Shaomin Guo, Hairun Jin, Qingjing Ouyang, Xu Long, Zhongbin Yan, Entang Tian

“…Metabolic fluctuations associated with the fertility gene were observed, particularly in processes related to aborted tapetal programmed cell death (PCD), which may contribute to reduced pollen fertility with abnormal pollen exine. …”
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Predictive Values of Preoperative Tests for Difficult Laryngoscopy and Intubation in Adult Patients at Tikur Anbessa Specialized Hospital by Tadese Tamire, Habtamu Demelash, Wosenyeleh Admasu

“…Difficulties in intubation have been associated with serious complications, such as brain damage or death, particularly when failed intubation has occurred. …”
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Computational analysis of congenital heart disease associated SNPs: unveiling their impact on the gene regulatory system by Shikha Vashisht, Costantino Parisi, Cecilia L. Winata

“…Abstract Congenital heart disease (CHD) is a prevalent condition characterized by defective heart development, causing premature death and stillbirths among infants. Genome-wide association studies (GWASs) have provided insights into the role of genetic variants in CHD pathogenesis through the identification of a comprehensive set of single-nucleotide polymorphisms (SNPs). …”
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Neuropeptides SP and CGRP Diminish the Moraxella catarrhalis Outer Membrane Vesicle- (OMV-) Triggered Inflammatory Response of Human A549 Epithelial Cells and Neutrophils by Daria Augustyniak, Justyna Roszkowiak, Izabela Wiśniewska, Jacek Skała, Daiva Gorczyca, Zuzanna Drulis-Kawa

“…Both neuropeptides exerted antiapoptotic activity through rescuing a significant fraction of A549 cells from OMV-induced cell death and apoptosis. Finally, CGRP caused an impairment of specific but not azurophilic granule exocytosis from neutrophils as shown by evaluation of gelatinase-associated lipocalin (NGAL) or CD66b expression and elastase release, respectively. …”
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The Rise of Transradial Artery Access for Percutaneous Coronary Intervention in Patients with Acute Coronary Syndromes in Australia by Ryan James Ocsan, Ata Doost, Paul Marley, Ahmad Farshid

“…The primary outcome was Major Adverse Cardiovascular Events (MACE), a composite of death, myocardial infarction (MI), target lesion revascularisation (TLR), or coronary artery bypass graft surgery (CABG) at 12 months. …”
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Coxiella Endocarditis as the Cause of Recurrent Fever and Brain Abscess in a Patient with Complex Congenital Heart Disease: A Case Report and Literature Review by Ioannis A. Ziogas, Alexandros P. Evangeliou, Olga Tsachouridou, Alexandra Arvanitaki, Afroditi Tsona, Vassilios Kamperidis, Marianthi Papagianni, Theofilos Panagiotidis, Ilias A. Tourtounis, George Giannakoulas, Symeon Metallidis

“…BCNIE is a life-threatening disease entity that can lead to severe complications, such as valve regurgitation, emboli, and death. Patients with congenital heart disease are particularly vulnerable to IE. …”
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Molecular evidence for the efficacy of PBM therapy in the treatment of oral lichen planus by Maria Zaharieva Mutafchieva, Milena Nenkova Draganova, Plamen Ivanov Zagorchev, Reem Hanna, Georgi Tomchev Tomov

“…It is assumed that blocking the cell death program and enhancing cell proliferation would be crucial to the healing process. …”
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Plasma-derived extracellular vesicles prime alveolar macrophages for autophagy and ferroptosis in sepsis-induced acute lung injury by Rongzong Ye, Yating Wei, Jingwen Li, Yu Zhong, Xiukai Chen, Chaoqian Li

“…In vivo, the inhibition of miR-223-3p effectively mitigated LPS-EV-induced inflammation and AM death in the lungs, as well as histological lesions. …”
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Mortality and Years of Life Lost in Diabetes Mellitus and Its Subcategories in China and Its Provinces, 2005–2020 by Feixue Wang, Wei Wang, Peng Yin, Yunning Liu, Jiangmei Liu, Lijun Wang, Jinlei Qi, Jinlin You, Lin Lin, Maigeng Zhou

“…At the same time, the burden of premature death was highest in the group≥80 years old, and ASMR increased from 236.02 per 100,000 in 2005 to 358.86 per 100,000 in 2020. …”
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Assessment of Knowledge about First Aid Methods, Diagnosis, and Management of Snakebite among Nursing Students: A Cross-Sectional Study from Palestine by Isra K. Kharusha, Suha S. Sulaiman, Ahmad M. Samara, Samah W. Al-Jabi, Sa’ed H. Zyoud

“…The estimated number of victims of venomous snakebites in Palestine is about 100 to 150 annually, with death occurring in 2 to 3 of them. This study was designed to assess the level of knowledge on the diagnosis and management of snakebites among nursing students in Palestine, as well as their attitude towards snakebites. …”
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Burden of type 2 diabetes and its relationship with human development index in Asian countries: Global Burden of Disease Study in 2019 by Seyed Ahmadreza Alinaghian, Shokoufeh Hamidzadeh, Afsaneh Badrizadeh, Zaher Khazaei, Amirhossein Souri, Victoria Momenabadi, Elham Goodarzi

“…Results The results indicated that the human development index (HID) was positively and significantly correlated with the incidence of type 2 diabetes in men (r = 0.481, P < 0.05) and women (r = 0.414, P < 0.05, but the correlation between death and the HDI was not significant in men and women (P > 0.05). …”
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Clinical importance of borderline proteinuria in nonazotemic cats and evaluation of other risk factors for the development of chronic kidney disease by Femke Mortier, Sylvie Daminet, Sofie Marynissen, Joren Verbeke, Dominique Paepe

“…Conclusions and Clinical Importance Borderline proteinuria should receive more attention in healthy mature adult and senior cats because it is associated with renal disease and death.…”
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Acute Exposure to a Precursor of Advanced Glycation End Products Induces a Dual Effect on the Rat Pancreatic Islet Function by Ghada Elmhiri, Luiz Felipe Barella, Didier Vieau, Sylvaine Camous, Paulo C. F. Mathias, Latifa Abdennebi-Najar

“…Chronic diseases are the leading cause of death worldwide. Advanced glycation end products, known as AGEs, are a major risk factor for diabetes onset and maintenance. …”
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Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface by Bianca A. Lepe, Christine R. Zheng, Owen K. Leddy, Benjamin L. Allsup, Sydney L. Solomon, Bryan D. Bryson

“…ABSTRACT Tuberculosis (TB) is the leading cause of infectious disease death and lacks a vaccine capable of protecting adults from pulmonary TB. …”
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Prognostic Value of Left Ventricular Diastolic Dysfunction in Patients Undergoing Cardiac Catheterization for Coronary Artery Disease by Hidekatsu Fukuta, Nobuyuki Ohte, Kazuaki Wakami, Toshihiko Goto, Tomomitsu Tani, Genjiro Kimura

“…During a followup of 1364 ± 628 days, 5 cardiac deaths and 20 unscheduled cardiovascular hospitalizations were observed. …”
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Racial and Socioeconomic Disparities in Out-Of-Hospital Cardiac Arrest Outcomes: Artificial Intelligence-Augmented Propensity Score and Geospatial Cohort Analysis of 3,952 Patients by Dominique J. Monlezun, Alfred T. Samura, Ritesh S. Patel, Tariq E. Thannoun, Prakash Balan

“…Compared to the safety net hospital system primarily serving poorer African Americans, the university hospital serving primarily higher income commercially and Medicare insured patients had the lowest odds of death (OR 0.45, p<0.001). Each additional $10,000 above median household income was associated with a decrease in the total number of cardiac arrests per zip code by 2.86 (95%CI -4.26- -1.46; p<0.001); zip codes with a median income above $54,600 versus the federal poverty level had 14.62 fewer arrests (p<0.001). …”
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