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  1. 3681
  2. 3682

    Decoding CKD-induced muscle atrophy through the critical role of lncRNA GAS5 and pyroptosis by Rong Huang, Xinying Tang, Shuang Liu, Lijing Sun

    Published 2025-03-01
    “…Transmission electron microscopy confirmed morphological signs of pyroptosis, a potentially causal cellular death form. Additionally, elevated levels of pyroptosis markers, such as NLRP3, cleaved caspase-1, and GSDMD-N, were observed in CKD mouse models and lipopolysaccharide (LPS)/ATP-stimulated C2C12 myotubes. …”
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  3. 3683

    Activating Transcription Factor 5 Promotes Tumorigenic Capability in Cervical Cancer Through the Wnt/β-Catenin Signaling Pathway by Shi F, Wei Y, Huang Y, Yao D

    Published 2025-01-01
    “…Fengjuan Shi,1,2 Yumei Wei,2 Yingmei Huang,2 Desheng Yao1 1Department of Gynecologic Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, People’s Republic of China; 2Department of Gynecology, the Fifth Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of ChinaCorrespondence: Desheng Yao, Email yaodesheng@gxmu.edu.cnPurpose: Cervical cancer is the fourth leading cause of cancer-related death in women. Furthermore, owing to its significant risk of recurrence or metastasis, the overall prognosis of patients with cervical cancer remains poor. …”
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  4. 3684

    Intratympanic administration of dexamethasone attenuates radiation induced damage to middle ear mucosa by Hyuk Chan Kwon, Sup Kim, Sheng Jin, Sun-Ae Shin, Jeong Han Lee, Min Jung Park, Soo Jeong Kim, Yong-Ho Park

    Published 2025-01-01
    “…Furthermore, DEX pretreatment downregulated the expression of cell death pathway markers in HMEE cells. Our collective results potentially support the use of DEX to reduce radiation-induced damage in the middle ear and may contribute to the development of future studies.…”
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  5. 3685

    Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights by Akram Hoseinzadeh, Seyed-Alireza Esmaeili, Reza Sahebi, Anahita Madani Melak, Mahmoud Mahmoudi, Maliheh Hasannia, Rasoul Baharlou

    Published 2025-02-01
    “…While the known physiological effectors of viable MSCs make a relative contribution, an innate property of MSCs as a therapeutic agent is their caspase-dependent cell death. These mechanisms may be involving the functional reprogramming of myeloid phagocytes via efferocytosis, the process by which apoptotic bodies (ABs) are identified for engulfment by both specialized and non-specialized phagocytic cells. …”
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  6. 3686

    Circulating Free RNA as a Therapeutic Evaluation in Diffuse Large B-cell Lymphoma: A Case Series from the Indonesian Cancer Center by Noorwati Sutandyo, Ikhwan Rinaldi, Lyana Setiawan, Christine Sugiarto, Yuniar Harris Prayitno

    Published 2024-10-01
    “…Cancer is still the leading cause of death worldwide. Despite advances in diagnosis, management with the rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate, and prednisone (R-CHOP) chemotherapy regimen, and careful clinical and radiologic evaluation, diffuse large B-cell lymphoma (DLBCL) still carries high recurrence in clinical practice. …”
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  7. 3687

    Cardiovascular Outcomes in Patients on Hemodialysis following Drug-Eluting versus Bare-Metal Coronary Stents by Amir F. Mohani, Srikanth Penumetsa, Amin Daoulah, Gregory Giugliano, Amir Lotfi

    Published 2018-01-01
    “…The primary outcome compared was a composite of all-cause death, myocardial infarction (MI), congestive heart failure (CHF), target vessel revascularization (TVR), and stroke at 30 days and one year. …”
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  8. 3688
  9. 3689

    Blood Pressure and Global Risk Assessment in a Swedish Population by Jenny Eckner, Charlotte A. Larsson, Lennart Råstam, Ulf Lindblad

    Published 2012-01-01
    “…Global risk of 10-year CVD death was estimated using the Swedish SCORE chart also accounting for additional risk from diabetes (SCORE-DM). …”
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  10. 3690

    The AhR pathway regulation in phthalates-induced cancer promotion, progression and metastasis: a scoping review by Mostafa Akbariani, Mahmoud Omidi, Zohreh Shahabi, Hamed Haghi-Aminjan, Amir Shadboorestan

    Published 2025-01-01
    “…Abstract Background Cancer remains a leading cause of death worldwide. Environmental factors, specifically endocrine-disrupting chemicals (EDCs), like phthalates, are increasingly being linked to cancer development. …”
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  11. 3691

    Clinical efficacy studies of the vaccine against feline panleukopenia, calicivirus infection and viral rhinotracheitis Carnifel PCH in kittens by T. S. Galkina, A. A. Komarova, A. M. Kiselev

    Published 2024-06-01
    “…Viral infections in cats can cause serious diseases and even death. Vaccines protect animals from diseases by inducing antibody production and cellular immune response. …”
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  12. 3692

    Visfatin Related to the Severity of Non-ST-Segment Elevation Acute Coronary Syndrome: A Retrospective Study of 164 Patients at a Tertiary Chest Pain Center by Meifan Zheng, Zhongwei Wu, Chaoquan Liu, Fei Xiao

    Published 2024-01-01
    “…Acute coronary syndrome (ACS) poses a pervasive threat to individuals grappling with cardiovascular afflictions, manifesting as unstable angina, non-ST-segment elevation myocardial infarction (NSTEMI), ST-segment elevation myocardial infarction (STEMI), or sudden cardiac death, depending on vascular obstruction’s extent and location. …”
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  13. 3693

    The incidence, mortality, and survival rate of colorectal cancer in Xiamen, China, from 2011 to 2020 by Lingxian Qiu, Wenting Luo, Youlan Chen, Zhinan Guo, Jiali Quan, Jiahuang Chi, Yingying Guan, Yue Huang, Yilan Lin

    Published 2025-01-01
    “…Abstract Introduction Currently, nearly one-third of newly diagnosed Colorectal cancer (CRC) cases and associated deaths worldwide are from China. Among Chinese provinces, Fujian exhibited the highest CRC mortality rate. …”
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  14. 3694

    Geopolitical Concerns Arising From Mining Activities in Some Parts of Nigeria and Cameroon by Rifkatu Nghargbu, K'tso Nghargbu, Shekwonyadu Iyakwari

    Published 2020-06-01
    “…The concerns range from negative impacts of mining such as pollution-induced health problems as a result of contaminated water and land, destruction of aquatic creatures, mining pits as death traps, as well as destruction of farm lands. …”
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  15. 3695

    SDES-YOLO: A high-precision and lightweight model for fall detection in complex environments by Xiangqian Huang, Xiaoming Li, Limengzi Yuan, Zhao Jiang, Hongwei Jin, Wanghao Wu, Ru Cai, Meilian Zheng, Hongpeng Bai

    Published 2025-01-01
    “…Abstract Falling is an emergency situation that can result in serious injury or even death, especially in the absence of immediate assistance. …”
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  16. 3696

    Brain Tumor Detection and Classification Using IFF-FLICM Segmentation and Optimized ELM Model by Suvashisa Dash, Mohammed Siddique, Satyasis Mishra, Demissie J. Gelmecha, Sunita Satapathy, Davinder Singh Rathee, Ram Sewak Singh

    Published 2024-01-01
    “…Brain cancer deaths are significantly increased in all categories of aged persons due to the abnormal growth of brain tumor tissues in the brain. …”
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  17. 3697

    Helicobacter pylori CagA and IL-1β Promote the Epithelial-to-Mesenchymal Transition in a Nontransformed Epithelial Cell Model by Haruki Arévalo-Romero, Isaura Meza, Gabriela Vallejo-Flores, Ezequiel M. Fuentes-Pananá

    Published 2016-01-01
    “…Gastric cancer is the third cause of cancer death worldwide and infection by Helicobacter pylori (H. pylori) is considered the most important risk factor, mainly by the activity of its virulence factor CagA. …”
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  18. 3698
  19. 3699

    Clinical Outcome between Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndrome and Diabetes by Peixun He, Xiaolin Luo, Jiabei Li, Yi Li, Xiaozeng Wang, Lan Huang, Jun Jin, Yaling Han

    Published 2021-01-01
    “…Ticagrelor did not improve the composite of nonfatal MI, target vessel revascularization, rehospitalization, stroke, and death from any cause; however, it significantly increased the incidence of bleeding events defined by the Bleeding Academic Research Consortium (BARC) criteria in Chinese patients with ACS and diabetes during the 6-month follow-up compared with clopidogrel.…”
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  20. 3700

    Feasibility of a pharmacist-led physical health monitoring for patients on antipsychotic medications: protocol for a longitudinal study by Fiona Kelly, Tien Ngoc Thi Bui, Elizabeth Hotham, Vijayaprakash Suppiah

    Published 2022-06-01
    “…Introduction Physical health conditions are the leading causes of death in people living with severe mental illness. …”
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