CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis by Jianqiang Wu, Lixia Chen, Peijun Wen

“…Abstract Metastasis is the leading cause of death in patients with cutaneous melanoma. CRIP1 (cysteine-rich protein 1) has been reported to be associated with malignant progression of several cancers. …”
Get full text

Frameworks for mitigating the risk of waterborne diarrheal diseases: A scoping review. by Chisala D Meki, Esper J Ncube, Kuku Voyi

“…<h4>Background</h4>Diarrhea is one of the major cause of death and morbidity around the world.<h4>Objectives</h4>This scoping review summarizes existing frameworks that aim to mitigate the risks of waterborne diarrheal diseases and describe the strengths and weaknesses of these frameworks.…”
Get full text

The birth and demise of a village within the vernacular community of Baduy in Banten, Indonesia by Irfan Sabarilah Hasim, Indah Widiastuti, Budi Faisal, Iwan Sudradjat

“…Villages may become abandoned due to various factors, including but not limited to 1) economic hardship, 2) leadership transition following the death of a leader, 3) dwindling population, and 4) natural disasters.…”
Get full text

Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment. by Yajia Chen, Jingxian Zhang, Weiqian Zheng, Hongwu Xu

“…In recent studies, regulatory cell death (RCD) has been identified as an effective mechanism to suppress glioma. …”
Get full text

CORRELATION BETWEEN APOPROTEIN B/APOPROTEIN A-I RATIO WITH HOMA IR VALUE (HOMEOSTATIC MODEL ASSESMENT INSULIN RESISTANCE) IN TYPE 2 DIABETES MELLITUS by Muhammad Rafli Afandi, Ferdy Royland Marpaung

“…Background: Diabetes mellitus (DM) is the seventh leading cause of death in the world (the occuring rate has reached 400 million people). …”
Get full text

Preclinical Evaluation of a Bone-Marrow Autograft Culture Procedure for Generating Lymphokine-Activated Killer Cells in Vitro by Hans-Georg Klingemann, Heather Deal, Dianne Reid, Connie J Eaves

“…Despite the use of high dose chemoradiotherapy for the treatment of acute leukemia. relapse continues to be a major cause of death in patients given an autologous bone marrow transplant. …”
Get full text

The Early Expression of HLA-DR and CD64 Myeloid Markers Is Specifically Compartmentalized in the Blood and Lungs of Patients with Septic Shock by Tomasz Skirecki, Małgorzata Mikaszewska-Sokolewicz, Grażyna Hoser, Urszula Zielińska-Borkowska

“…Pulmonary monocytes display a higher level of HLA-DR activation compared to peripheral blood monocytes but the expression of neutrophil CD64 is similar on lung and circulating cells. Death in septic patients was effectively predicted by neutrophil CD64 but not monocytic HLA-DR. …”
Get full text

A Novel In Situ Dendritic Cell Vaccine Triggered by Rose Bengal Enhances Adaptive Antitumour Immunity by Lanlin Zhang, Jiangyuan Du, Qian Song, Chufan Zhang, Xianghua Wu

“…Recent studies have shown that Rose Bengal (RB) can effectively induce immunogenic cell death (ICD) in cancer cells, presenting whole tumour antigens for DC processing and presentation. …”
Get full text

Time series analysis of dengue incidence in Bandung City, Indonesia using a ARIMA model by Agung Sutriyawan, Martini Martini, Dwi Sutiningsih, Farid Agushybana, Nur Endah Wahyuningsih, Victor Eneojo Adamu, Hairil Akbar, Matheus Aba

“…Dengue is a public health problem that leads to death. This disease is necessary to monitor to reduce its impact on the community. …”
Get full text

Characterization of Older Adults with Colorectal Cancer in the Community by Belkis Álvarez Escobar, Juan Carlos Mirabal Requena, José Alejandro Concepción Pacheco, Javier Cruz Rodríguez, Ydalsys Naranjo Hernández

“…In Cuba it is a major health problem due to its high incidence and mortality; it is the third cause of death in the general population. <br /><strong>Objective:</strong> to characterize older adults with colorectal cancer at the Rudesindo García del Rijo Sur Polyclinic in the Sancti Spíritus province.…”
Get full text

The effect of sarpogrelate compared to aspirin in high- or very-high-risk diabetes for primary prevention by Soo Hyun Kang, Kilyoon Pack, Jung Ho Kim, Youngwoo Jang

“…The efficacy was a composite of all-cause death, myocardial infarction (MI) and stroke, whereas overall bleeding included intracranial hemorrhage (ICH) and gastrointestinal (GI) bleeding. …”
Get full text

Legal and Organizational Principles of Militia Activities of the Ukrainian Soviet Socialist Republic in 1956 by V. A. Grechenko

“…The year 1956 was significant both in the history of Ukraine and the USSR, but also for world history. The death of I.V. Stalin in 1953 marked the beginning of the partial liberalization of the political regime in the Soviet Union; the strongest impetus for the continuation and intensification of this process was in 1956, the year of the XX Congress of the CPSU and the CPSU Central Committee Resolution “On overcoming the Stalin’s cult of personality and its consequences”, where a lot of terrible truth about the Soviet past was told for the first time. …”
Get full text

Prognostic Value of Microvascular Density in Dukes A and B (T1–T4, N0, M0) Colorectal Carcinomas by Rafael Uribarrena A, Javier Ortego, Javier Fuentes, Nuria Raventós, Pilar Parra, Rafael Uribarrena E

“…The mean number of vessels was 37.37/200x field, and the mean vascular area was the 3.972%. 30% of the patients with <37 vessels/field, and 21% of the patients with >37 vessels/field, experienced recurrence/death. The 35% of patients with <4% of vascular area died following recurrence, compared with 14% of patients with ≥4% of vascular area. …”
Get full text

Clinical Features and Rehabilitation Needs in Patients with Neuroinvasive West Nile Virus Infection: A Retrospective Analysis in an Area of High Incidence by Maria Chiara Maccarone, Francesco Piccione, Marina Munari, Noemi Faccin, Gianluca Regazzo, Luisa Barzon, Stefano Masiero

“…Data included demographics, comorbidities, length of hospital stay, days at PMR evaluation, and rehabilitation duration until discharge or death, alongside objective examination findings and Barthel Index scores. …”
Get full text

The pathogenesis of COVID-19: Hypercoagulation and D-dimer in thrombotic complications by Leonid DUBEY, Halyna LYTVYN, Olha DOROSH, Nataliya DUBEY, Olena KOZLOVA, Michal PRUC, Nina KUBIKOWSKA, Lukasz SZARPAK, Kavita BATRA, Francesco CHIRICO, Gabriella NUCERA, Svitlana DOAN, Uljana SHEVTSIV

“…The focus of existing treatment to alleviate fibrinolysis in patients with COVID-19 is the use of systemic fibrinolytic therapy given thrombotic pathology in severe forms of COVID-19 which may lead to death. However, fibrinolytic therapy may be harmful in the advanced stages of COVID-19, when the status of disseminated intravascular coagulation (DIC) changes from suppressed fibrinolysis to its enhancement during the progression of the disease. …”
Get full text

Alcohol consumption associated with suicidal ideation, and suicide attempts in substance users: A cross-sectional study of an addiction registry in western Iran. by Vahid Farnia, Mahsa Mohebian, Omran Davarinejad, Denise A Hien, Safora Salemi, Sara Hookari, Hafez Bajoghli, Bahareh Rahami

“…<h4>Conclusion</h4>Our study results revealed that alcohol consumption among individuals with SUDs is associated with increased rates of suicidal ideation, attempts, and death. Therefore, clinicians should consider it as a separate suicide risk factor.…”
Get full text

Transient Ischemic Attack and Ischemic Stroke in Danon Disease with Formation of Left Ventricular Apical Thrombus despite Normal Systolic Function by Takeshi Tsuda, Amanda J. Shillingford, Jane Vetter, Vinay Kandula, Badal Jain, Joel Temple

“…Early morbidity and mortality due to heart failure or sudden death are known in Danon disease, more in males than in females. …”
Get full text

Contaminated Pond Water Favors Cholera Outbreak at Haibatpur Village, Purba Medinipur District, West Bengal, India by Dilip Kumar Biswas, Rama Bhunia, Dipankar Maji, Palash Das

“…AR among men was higher 6% (25/404) than women. There was no death. V. cholerae 01 Eltor Ogawa was isolated from one (1/4) stool specimen. …”
Get full text

IDMPF: intelligent diabetes mellitus prediction framework using machine learning by Leila Ismail, Huned Materwala

“…Diabetes is a chronic disease and one of the 10 causes of death worldwide. It is expected that the total number of diabetes will be 700 million in 2045; a 51.18% increase compared to 2019. …”
Get full text

Remediating Cambridge: Human and Horse Co-Relationality in a Culture of Mis-Re-Presentation by Francesca A. Brady, Jennifer McDonell

“…Adopting a phenomenologically informed intersectional feminist ethics of care perspective, a counternarrative to the gendered, racialised and essentialising rights-based judgements about Cambridge’s illness and eventual death that dominated the popular media is provided. …”
Get full text