Predictive factors associated with short‐term mortality in cats with feline infectious peritonitis treated with remdesivir or GS‐441524 or both by Sho Goto, Tsuyoshi Kamiyoshi, Ryota Iwasaki

“…Factors associated with short‐term mortality, defined as death within 84 days, were identified. Univariate analysis a t‐test, Mann‐Whitney U test, or Fisher's exact test and multivariate logistic regression were performed to assess patient characteristics and clinicopathological variables between survivors and nonsurvivors. …”
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Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis by Xiaofan Sun, Yue Li, Juan Du, Fangshu Liu, Caiping Wu, Weihao Xiao, Guopan Yu, Xiaowei Chen, Robert Peter Gale, Hui Zeng

“…Abstract Sphingolipid, ceramide for example, plays an essential role in regulating cancer cell death. Defects in the generation and metabolism of ceramide in cancer cells contribute to tumor cell survival and resistance to chemotherapy. …”
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A Concept Mapping Study of Physicians’ Perceptions of Factors Influencing Management and Control of Hypertension in Sub-Saharan Africa by Juliet Iwelunmor, Sarah Blackstone, Joyce Gyamfi, Collins Airhihenbuwa, Jacob Plange-Rhule, Bamidele Tayo, Richard Adanu, Gbenga Ogedegbe

“…Hypertension, once a rare problem in Sub-Saharan Africa (SSA), is predicted to be a major cause of death by 2020 with mortality rates as high as 75%. …”
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Comparison between Endoscopic Ultrasound-Guided Antegrade and Transluminal Stent Implantation in Distal Malignant Biliary Obstruction after Failed ERCP by Yonghua Shen, Ying Lv, Xiaojiao Zheng, Wei Zhan, Senlin Hou, Lin Zhou, Jun Cao, Bin Zhang, Lei Wang, Hao Zhu, Lichao Zhang

“…The median time to stent dysfunction or patient death in TLS and AGS groups was 53 and 81 days, respectively (P=0.017). …”
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A Review on the Role of Human Solute Carriers Transporters in Cancer by Md. Shafiul Hossen, Mohammed Shafin Ul Islam, Mohammad Yasin, Mohammed Ibrahim, Abhijit Das

“…Furthermore, they contribute to the activation of PI3K/AKT signaling, which has an impact on the growth, invasion, and death of cancer cells. Thus, SLC transporters become a potential therapeutic target that plays a crucial role in drug resistance, tumor microenvironment regulation, and modulation of immune response. …”
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Modeling and simulation for toxicity assessment by Cristina Anton, Jian Deng, Yau Shu Wong, Yile Zhang, Weiping Zhang, Stephan Gabos, Dorothy Yu Huang, Can Jin

“…The effect of various toxicants on growth/death and morphology of human cells is investigated using the xCELLigence Real-Time Cell Analysis High Troughput in vitro assay. …”
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Reaction of the Liver upon Long-Term Treatment of Fluoxetine and Atorvastatin Compared with Alcohol in a Mouse Model by Zhiliang Chen, Tony C. H. Chow, Shicong Wang, Gigi C. T. Leung, Sharon L. Y. Wu, David T. Yew

“…PCNA and MCM2 showed increased proliferation in the livers of all three groups, with the ethanol group having the highest number of positive cells followed by atorvastatin and then the fluoxetine group. As for cell death, both ethanol and fluoxetine groups showed significantly more apoptosis than control in TUNEL and activated caspase-3, while in the atorvastatin group, activated caspase-3 positive cells increased significantly, but the increase in TUNEL-positive cells did not reach statistical significance.…”
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Rural-Urban Disparity in Premature Cancer Mortality in Young People Aged 15–44 Years in China, 2004–2021 by Chunrong Chen, Xing Xing, Shaojie Li, Bo Qu, Chunyu Liu, He Zhu, He Zhu

“…ObjectiveThis study aims to examine and compare premature cancer mortality in young people aged 15–44 years old between rural and urban areas to inform early-onset cancer prevention.MethodsThe data were obtained from the China Death Surveillance Datasets from 2004 to 2021. The study sample consisted of cancer deaths of young people aged 15–44 years old. …”
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Clinical signs and post-mortem lesions caused by clostridial enterotoxemia in rabbits by A. S. Metleva, M. N. Khakimzyanova, E. E. Sionikhin

“…Clinical manifestation begins with bloating, weakness, inappetence, which ultimately lead to death. Observations have shown that the risk group includes rabbit kits weaned from the 35–77-day old does. …”
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Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent by V. A. Graham, G. J. Hatch, K. R. Bewley, K. Steeds, A. Lansley, S. R. Bate, S. G. P. Funnell

“…Using human and cynomolgus macaque serum with known ELISA antibody titres against both vaccine components, we have shown that passive immunisation of human and nonhuman primate serum provides a reproducible delay in median time to death in mice exposed to a lethal aerosol of plague. …”
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Effects of Aminoglycoside Antibiotics on Human Embryonic Stem Cell Viability during Differentiation In Vitro by Divya S. Varghese, Shama Parween, Mustafa T. Ardah, Bright Starling Emerald, Suraiya A. Ansari

“…However, during directed differentiation towards neural and hepatic fate, significant cell death was noted through the activation of caspase cascade. …”
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Epidemiology of Pancreatic Carcinoma in Canada: 1931 to 1985 by Anthony Ayiomamitis

“…Pancreatic carcinoma accounts for approximately one of every 20 deaths from cancer and one out of every 30 new cases of cancer in Canada. …”
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Ciprofloxacin and Clozapine: A Potentially Fatal but Underappreciated Interaction by Jonathan M. Meyer, George Proctor, Michael A. Cummings, Laura J. Dardashti, Stephen M. Stahl

“…The postmortem femoral clozapine plasma level was dramatically elevated at 2900 ng/mL, and the cause of death was listed as acute clozapine toxicity. Conclusion. …”
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Bioanthropological and Biomechanical Perspectives on Skeletal Senescence Variation by Sayf Muhammad Alaydrus, Muhamad Andri Jauhari

“…Literature Review: Age-related skeletal cellular death and imbalance contributes to bone damage in elders. …”
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The Effects of Baclofen for the Treatment of Gastroesophageal Reflux Disease: A Meta-Analysis of Randomized Controlled Trials by Shujie Li, Shengying Shi, Feng Chen, Jingming Lin

“…No serious adverse events or death events were reported, and there were no significant differences in the overall adverse events between baclofen and placebo. …”
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Determinant domain in prognosis evaluation of the septic patient in the intensive care unit. by Alexis Díaz Mesa, Rubén Bembibre Taboada, Alexis Suárez del Villar Labastida, Dagmaris Losa Pérez

“…<strong>Background:</strong> Sepsis is the most frequent cause of death in critical ill patient. The necessity to have with evolutionary and predictable markers for medical routines is a tangible fact. …”
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Proteomic Analysis of the Vitreous following Experimental Retinal Detachment in Rabbits by Nakul Mandal, Geoffrey P. Lewis, Steven K. Fisher, Steffen Heegaard, Jan U. Prause, Morten la Cour, Henrik Vorum, Bent Honoré

“…The pathogenesis of rhegmatogenous retinal detachment (RRD) remains incompletely understood, with no clinically effective treatment for potentially severe complications such as photoreceptor cell death and proliferative vitreoretinopathy. Here we investigate the protein profile of the vitreous following experimental retinal detachment using a comparative proteomic based approach. …”
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Anticardiolipin Autoantibodies as Useful Biomarkers for the Prediction of Mortality in Septic Patients by Amal Abouda, Z. Hajjej, A. Mansart, W. Kaabechi, D. Elhaj Mahmoud, O. Lamine, E. Ghazouani, M. Ferjani, I. Labbene

“…The primary study endpoint was ICU mortality defined as death before ICU discharge. Secondary end points included correlation between SOFA score and biological parameters. …”
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Modern approaches to production of safe and effective genetically modified rabies vaccines for animals by M. I. Doronin, A. Mazloum, D. V. Mikhalishin, M. N. Mitrofanova, A. Yu. Sukharkov, V. V. Kiseleva, A. V. Sprygin

“…The disease causes significant economic losses associated with the death of animals, outbreak consequences, strict restrictions on domestic and international trade in livestock products, preventive and quarantine measures, laboratory tests. …”
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Anti-proliferative and photodynamic activities of Senna didymobotrya (Fresen.) leaf alkaloid-rich extracts against breast cancer cells by Kolawole A. Olofinsan, Heidi Abrahamse, Blassan P. George

“…Abstract Background Amongst all neoplastic diseases, breast cancer represents a major cause of death among the female population in developed and developing countries. …”
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