Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascu... by J. Matthew Rhett, Hongjun Wang, Heather Bainbridge, Lili Song, Michael J. Yost

“…Connexin43 (Cx43) channels play a key role in early inflammation and have proven to be viable therapeutic targets. Even if cell death due to early inflammation is avoided, insufficient vascularization is a primary obstacle to maintaining the viability of implanted cells. …”
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Novel mitochondrial-targeted alkyl chains act as fungal specific inhibitors of C. neoformans by Elizabeth S. M. Edrich, Luke Young, John Spencer, Andrew McGown, Anthony L. Moore, Campbell W. Gourlay

“…Further analysis suggested that the antifungal properties of ALTOX094 and ALTOX102 were attributable to different modes of action and forms of cell death, governed largely by the alkyl chain length used to tether Colletochlorin B to the mitochondria targeting triphenylphosphine (TPP) moiety. …”
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A Case of Non-Small Cell Lung Cancer with Possible “Disease Flare” on Nivolumab Treatment by Shotaro Chubachi, Hiroyuki Yasuda, Hidehiro Irie, Koichi Fukunaga, Katsuhiko Naoki, Kenzo Soejima, Tomoko Betsuyaku

“…Recent clinical trials proven the clinically significant efficacy and tolerability of nivolumab, a programmed death 1 (PD-1) inhibitor, in previously treated patients with non-small cell lung cancer (NSCLC). …”
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Burden of Comorbidities and Healthcare Resource Utilization Among Medicaid-Enrolled Extremely Premature Infants by Meredith E. Mowitz, Wei Gao, Heather Sipsma, Pete Zuckerman, Hallee Wong, Rajeev Ayyagari, Sujata P. Sarda

“…Data from the index date (birth) up to 2 years corrected age or death, stratified by GA (EP, ≤28 wGA; very premature \[VP\], >28 to <32 wGA; and moderate to late premature \[M-LP\], ≥32 to <37 wGA), were compared using unadjusted and adjusted generalized linear models. …”
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PAIVS: prediction of avian influenza virus subtype by Hyeon-Chun Park, Juyoun Shin, Sung-Min Cho, Shinseok Kang, Yeun-Jun Chung, Seung-Hyun Jung

“…Highly pathogenic avian influenza (HPAI) viruses have caused severe respiratory disease and death in poultry and human beings. Although most of the avian influenza viruses (AIVs) are of low pathogenicity and cause mild infections in birds, some subtypes including hemagglutinin H5 and H7 subtype cause HPAI. …”
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Role of Pulse Oximetry Screening for Detection of Life Threatening Congenital Heart Detects in Newborn by Aso Faeq Salih, Adnan Mohammed Hamawand, Riyadh Abd Aljabbar Sattar

“…However, if such defects are not diagnosed in earlier time, therefore a severe hypoxemia, shock, acidosis and death are considered of some potential sequelae. …”
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An Innocent Appearing Subcutaneous Nodule Diagnoses a Small Cell Lung Cancer in a Never-Smoker Female by Nupur Sinha, Masooma Niazi, Gilda Diaz-Fuentes, Richard Duncalf

“…Lung cancer among never-smokers is recognized as the 7th most common cause of cancer death globally. Adenocarcinoma is the most commonly reported histology. …”
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Trend of skin cancer mortality and years of life lost in China from 2013 to 2021 by Jingyi Li, Jiaqi Zeng, Yuanchao Yang, Biran Huang

“…This study aimed to estimate the mortality trends of skin cancer in China within 2013–2021.MethodsA retrospective analysis of skin cancer deaths within 2013–2021 was performed using the China death cause surveillance dataset compiled by the National Health Commission Statistics Information Center and the China Center for Disease Control and Prevention Chronic Non-Communicable Diseases Prevention and Control Center. …”
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Biochemical Behaviours of Salmeterol/Fluticasone Propionate in Treating Asthma and Chronic Obstructive Pulmonary Diseases (COPD) by Hilla Mills, Ronald Acquah, Nova Tang, Luke Cheung, Susanne Klenk, Ronald Glassen, Magali Pirson, Alain Albert, Duong Trinh Hoang, Thang Nguyen Van

“…The respiratory tract may be blocked, robbed of the adequate amounts of oxygen; hence, death ensues if a quick medical attention is not provided. …”
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Chikungunya: From Hypothesis to Evidence of Increased Severe Disease and Fatalities by Carlos Brito, Melissa Barreto Falcão, Maria de Fatima Pessoa Militão de Albuquerque, Thiago Cerqueira-Silva, Maria Glória Teixeira, Rafael Freitas de Oliveira Franca

“…These findings aim to expand disease classifications in international guidelines and raise awareness among healthcare professionals to better identify severe CHIKV cases and related deaths. Studies were identified through PubMed using the search terms “chikungunya”, “death”, “severe”, “pathogenesis”, and “pathophysiology”.…”
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Image Characterization of Cancer of the Colon by Thaimi Conde Cueto, Martha Yudey Rodríguez Pino, Pedro Juan Barrios Fuentes, Bárbara Aleida García Hernández, Julio Suz Piña, Nery M. Díaz Yanes

“…<strong>Background:</strong> Cancer of the colon is the second cause of death due to cancer worldwide, alter lung cancer in males and breast cancer in females. …”
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The link between spreading depolarization and innate immunity in the central nervous system by Kadir Oguzhan Soylu, Muge Yemisci, Hulya Karatas

“…Abstract Spreading depolarization (SD) is a complex event that induces significant cellular stress in the central nervous system, leading to a robust inflammatory response without causing cell death in healthy tissues which may be called as neuro-parainflammation. …”
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Tuberculous Osteomyelitis of the Scapular Spine Revealing HIV-1 Infection by Khaoula Idsaid, Malika Idalene, Khadija Danaoui, Wiam Ait Driss, Rania Elfargani, Nabila Soraa, Noura Tassi

“…Tuberculosis is no longer confined to developing nations; it persists as a significant contributor to illness and death on a global scale. The subtle clinical manifestation and association with human immunodeficiency virus infection poses obstacles for early diagnosis and management. …”
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An improved soft voting-based machine learning technique to detect breast cancer utilizing effective feature selection and SMOTE-ENN class balancing by Indu Chhillar, Ajmer Singh

“…Abstract Breast cancer is the primary cause of death among women globally, and it is becoming more prevalent. …”
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Dynamic interplay of autophagy and membrane repair during Mycobacterium tuberculosis Infection. by Jacques Augenstreich, Anna T Phan, Charles N S Allen, Anushka Poddar, Hanzhang Chen, Lalitha Srinivasan, Volker Briken

“…Interferon-gamma pre-treatment did not affect LC3 recruitment frequency or autophagosome acidification but increased the susceptibility of the macrophage to Mtb-induced cell death. LC3 recruitment and lysotracker staining were mutually exclusive events, alternating on some MCVs multiple times thus demonstrating a reversible aspect of the autophagy response. …”
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Complications, Reoperations, and Nutrient Deficiencies Two Years after Sleeve Gastrectomy by Nicole Pech, Frank Meyer, Hans Lippert, Thomas Manger, Christine Stroh

“…Major complications were observed in 9.8% of the patients, with 1 death. During follow up 51.2% of patients were supplemented with iron, 36.6% with zinc, 37.8% with calcium, 26.8% with vitamin D, 46.3% with vitamin B12 and 41.5% with folic acid. …”
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An ivory statuette depicting the god Thanatos discovered near Tomis (Moesia Inferior) by Ingrid Petcu-Levei, Radu Petcu

“…It was made as a representation of the god Thanatos, the personification of the Angel of Death in Greek and Roman mythology. Unfortunately, the statuette is incomplete; the left hand and parts of the legs are missing, along with the wings originally located on its back. …”
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Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets by Zhiyang Yin, Guanlu Shen, Minjie Fan, Pengfei Zheng

“…Ferroptosis is an iron-dependent form of programmed cell death associated with lipid peroxidation. This review provides an in-depth analysis of the complex relationship between lipid metabolic reprogramming and associated ferroptosis in OS from the perspective of metabolic enzymes and metabolites. …”
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A Smart Machine Learning Model for the Detection of Brain Hemorrhage Diagnosis Based Internet of Things in Smart Cities by Hang Chen, Sulaiman Khan, Bo Kou, Shah Nazir, Wei Liu, Anwar Hussain

“…In terms of efforts made for helping the patients using IoT-based solutions, experts exploit capabilities of the machine learning algorithms to provide efficient solutions in hemorrhage diagnosis. To reduce the death rates and propose accurate treatment, this paper presents a smart IoT-based application using machine learning algorithms for the human brain hemorrhage diagnosis. …”
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Safe Transition to Pembrolizumab following Ipilimumab-Induced Guillain-Barré Syndrome: A Case Report and Review of the Literature by Nicholas Gravbrot, Katalin Scherer, Srinath Sundararajan

“…Restaging revealed thoracic lymph node involvement, and he was then started on pembrolizumab (programmed cell death protein-1 inhibitor). He experienced a complete tumoral response to pembrolizumab, and he tolerated treatment well without recurrent weakness. …”
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