The dynamics of a delay model of hepatitis B virus infection with logistic hepatocyte growth by Steffen Eikenberry, Sarah Hews, John D. Nagy, Yang Kuang

“…Chronic HBV affects 350 million people and can lead to death through cirrhosis-inducedliver failure or hepatocellular carcinoma. …”
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Development of a high-throughput screening system for identification of novel reagents regulating DNA damage in human dermal fibroblasts by Bae Seunghee, An In-Sook, An Sungkwan

“…In the second step, we validated certain effective reagents identified in the first step by analyzing the cell cycle, evaluating cell death, and performing HPRT-DNA sequencing in DREAM-F cells treated with these reagents and UVB. …”
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Investigation of the trends and associated factors of ovarian cancer in Indonesia: A systematic analysis of the Global Burden of Disease study 1990-2021. by Brahmana Askandar Tjokroprawiro, Khoirunnisa Novitasari, Renata Alya Ulhaq, Hanif Ardiansyah Sulistya, Santi Martini

“…<h4>Results</h4>Indonesia had 13 250 (8 574-21 565) ovarian cancer cases in 2021, with 5 296 (3 520-8958) deaths and 186 917 (121 866-309 820) DALYs. The burden increased by 233.53% for new cases, 221.95% for mortalities, and 206.65% for DALYs. …”
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Factors Affecting the Occurrence of Out-of-Hospital Sudden Cardiac Arrest by Izabella Uchmanowicz, Wiesław Bartkiewicz, Jarosław Sowizdraniuk, Joanna Rosińczuk

“…The main risk factor of OHSCA is coexistence of external cause leading to illness or death (ICD Group V-10) as well as the occurrence of diseases from the group of endocrine disorders (group E), in particular diabetes. …”
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Suicide prevention curriculum development for health and social care students: Protocol for a scoping review. by Kerrie Gallagher, Clíodhna O' Brien, Michelle O' Driscoll, Doireann Ní Dhálaigh, Paul Corcoran, Eve Griffin

“…Suicide has become a serious public health concern and international research has shown that the majority of individuals who die by suicide had receive healthcare in the year prior to their death. This presents an opportunity for suicide prevention by strategically training healthcare students in suicide prevention knowledge and skills. …”
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Role of Dexmedetomidine by Improving Sleep Quality and Pain Control in Covid-19 Patients by Maliha Khalid, Faheem Feroze, Saad bin Qamar, Naseem Abbas, Saeed Farooq, Aisha Siddiqui

“…INTRODUCTION: Covid-19 disease is a deadly contagious disease with milder symptoms to a more severe form with acute respiratory failure, septic shock leading to even death. Literature study shows High Flow Nasal Oxygen therapy and prolonged prone position sessions to be beneficial in the treatment of ARDS, however, to facilitate those sessions, a sedative and anxiolytic agent must be added in the treatment. …”
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Vitamin D as a predictor of negative outcomes in hospitalized COVID-19 patients: An observational study by Volodymyr Bogomaz, Sofiia Shatylo

“…Patients were divided into two groups based on their serum vitamin D level: with adequate vitamin D (≥ 30 ng/ml) and with low vitamin D (\<30 ng/ml). Outcomes such as death and the need for respiratory support were recorded…”
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Role of circRMRP and circRPL27 in chronic obstructive pulmonary disease by Li JianFang, Zhang PengFei, Zeng XianJing, Liu Rong

“…Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability worldwide, and circRNA dysregulation is functionally associated with COPD. …”
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Fibroblast Growth Factor-2 and the HIV-1 Tat Protein Synergize in Promoting Bcl-2 Expression and Preventing Endothelial Cell Apoptosis: Implications for the Pathogenesis of AIDS-As... by Cecilia Sgadari, Giovanni Barillari, Clelia Palladino, Stefania Bellino, Brunella Taddeo, Elena Toschi, Barbara Ensoli

“…Upregulation of Bcl-2 expression by combined FGF-2 and Tat occurs also in vitro, and this protects human primary endothelial cells from programmed cell death. As Bcl-2 is expressed in human KS lesions in a fashion paralleling the progression of the disease, these findings suggest a molecular mechanism by which Tat and FGF-2 cooperate in KS maintenance and progression in HIV-infected individuals.…”
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Exclusive Cutaneous and Subcutaneous Sarcoidal Granulomatous Inflammation due to Immune Checkpoint Inhibitors: Report of Two Cases with Unusual Manifestations and Review of the Lit... by Narciss Mobini, Rummit Dhillon, Jason Dickey, Jordan Spoon, Kaviyon Sadrolashrafi

“…The primary target antigens are cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), a downregulator of T-cell activation, and programmed cell death-1 receptor (PD-1), a regulator of T-cell proliferation. …”
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WHAT ARE THE CAUSES AND TYPES OF FARMER TRAUMA? A LITERATURE REVIEW by Arista Maisyaroh, Eko Prasetya Widianto, Syaifuddin Kurnianto

“…At the same time, the types of trauma in farming accidents were soft tissue injuries, concussions, fractures, avulsions, amputations, and infections to death. Conclusion: Work-induced injuries directly affected farmers' lives, so it is necessary to increase knowledge in recognizing the factors causing injuries and management according to the type of injury experienced.…”
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A Comparative Systematic Review of the Optimal CD4 Cell Count Threshold for HIV Treatment Initiation by Babatunde Olubajo, Kathryn Mitchell-Fearon, Oluseye Ogunmoroti

“…HIV infection is no longer characterized by high morbidity, rapid progression to AIDS, and death as when the infection was first identified. …”
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Marine Diterpenoids as Potential Anti-Inflammatory Agents by Yisett González, Daniel Torres-Mendoza, Gillian E. Jones, Patricia L. Fernandez

“…The inflammatory response is a highly regulated process, and its dysregulation can lead to the establishment of chronic inflammation and, in some cases, to death. Inflammation is the cause of several diseases, including rheumatoid arthritis, inflammatory bowel diseases, multiple sclerosis, and asthma. …”
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Invasive Aspergillosis in a Patient with Stage III (or 3a or 3b) Non-Small-Cell Lung Cancer Treated with Durvalumab by Ashish Gupta, Aung Tun, Katy Ticona, Aam Baqui, Elizabeth Guevara

“…Durvalumab is a therapeutic monoclonal antibody that blocks the checkpoint inhibitor, programmed death ligand 1 (PD-L1), resulting in T-cell activation and an antitumor response. …”
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Developmental defects in ectodermal appendages caused by missense mutation in edaradd gene in the nfr mangrove killifish kryptolebias marmoratus by Hussein A. Saud, Paul A. O’Neill, Brian C. Ring, Tetsuhiro Kudoh

“…Illumina RNAseq with 3 embryos each from mutants, siblings and the parental WT strain Hon9 (only 9 embryos as total) identified a mutation in the edaradd in a highly conserved C-terminal death domain. Edaradd is known as a cytoplasmic accessory protein for the Ectodysplasin A (EDA) signalling pathway. …”
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Pathogenesis of Severe Clinical Pictures of Influenza A (H1 N1). Some answers and new doubts. by Alfredo Darío Espinosa Brito, Ángel Julio Romero Cabrera

“…This situation may lead the patient to the intensive care unit and could cause his death, although the figures of such cases stay relatively low, in relation to other epidemics of seasonal Influenza. …”
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Go Back!: Reclaiming Indigenous Visibility in Literary, Cultural, and Environmental Spaces of Pakistan by Anam Feroz

“…To illustrate this argument, I have chosen two novels by Mustansar Hussain Tarar, Sorrows of Sarasvati originally published as Bahao, and Love in the Shade of Death originally published as Qurbat e Marg Mein Muhabbat. …”
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The Association between Systemic Immune-Inflammation Index and All-Cause Mortality in Acute Ischemic Stroke Patients: Analysis from the MIMIC-IV Database by Shaosheng Wu, Xiaoting Shi, Quan Zhou, Xiangjie Duan, Xiongfei Zhang, Huajing Guo

“…Acute ischemic stroke (AIS) is a devastating disease and remains the leading cause of death and disability. This retrospective study aims to investigate associations between systemic immune-inflammation index (SII) and all-cause mortality in patients with AIS. …”
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Effects of Bariatric Surgeries on Fetuin-A, Selenoprotein P, Angiopoietin-Like Protein 6, and Fibroblast Growth Factor 21 Concentration by Jakub Poloczek, Wojciech Kazura, Ewa Kwaśnicka, Janusz Gumprecht, Jerzy Jochem, Dominika Stygar

“…It is also associated with the leading causes of death, including type 2 diabetes mellitus, cardiovascular diseases, and numerous types of cancer. …”
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The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review by M. R. Griffiths, P. Gasque, J. W. Neal

“…Phagocytic receptors (CD14, CD36, TLR–4) clear “not self” pathogens; neurons and glia express “death signals” to initiate apoptosis in T cells.The complement opsonins C1q, C3, and iC3b facilitate the clearance of apoptotic cells by interacting with CR3 and CR4 receptors. …”
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