Detection and Validation of A2 Milk Suitable for Consumers Having Milk Intolerance by ELISA Method by Mediha Esra Yayla

“…Studies showed that A1 milk consumption may cause diabetes, coronary heart disease, arteriosclerosis, sudden infant death, and is associated with autism and schizophrenia. …”
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Protocol of an Efficacy Study on Nursing Consultation in Weight Management and Metabolic Syndrome Based on the Carbohydrate–Insulin Theory in Individuals with First-Episode Psychos... by Lander Madaria, Claudia Aymerich, Ana Catalan, Miguel Angel Gonzalez-Torres

“…<b>Background</b>: Individuals with severe mental illness live, on average, up to 30 years less than the general population, with cardiovascular disease being the leading cause of death. Metabolic syndrome (MetS) plays a significant role in this, making it crucial to manage this issue in individuals with psychosis at the onset of the illness. …”
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The Isosteroid Alkaloid Imperialine from Bulbs of Fritillaria cirrhosa Mitigates Pulmonary Functional and Structural Impairment and Suppresses Inflammatory Response in a COPD-Like... by Dongdong Wang, Qingdan Du, Houcong Li, Shu Wang

“…Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the world. Present therapies for COPD have limited effect on reducing the progression of COPD and suppressing the inflammatory response in the lung. …”
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Welfare of horses at slaughter by EFSA Panel on Animal Health and Welfare (AHAW), Søren Saxmose Nielsen, Julio Alvarez, Anette Boklund, Sabine Dippel, Fernanda Dorea, Jordi Figuerola, Mette Herskin, Miguel Angel Miranda Chueca, Eleonora Nannoni, Romolo Nonno, Anja Riber, Karl Stahl, Jan Arend Stegeman, Hans‐Hermann Thulke, Frank Tuyttens, Christoph Winckler, Mohan Raj, Antonio Velarde, Denise Candiani, Yves Van der Stede, Virginie Michel

“…The entire slaughter procedure, from arrival at the slaughterhouse until death, is divided into three phases: Phase 1 – pre‐stunning, Phase 2 – stunning and Phase 3 – bleeding. …”
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Progress in Therapy Development for Amyotrophic Lateral Sclerosis by Kalina Venkova-Hristova, Alexandar Christov, Zarine Kamaluddin, Peter Kobalka, Kenneth Hensley

“…The result is a loss of neuronal homeostasis and progressive die-back of motor axons culminating in death of the afflicted motor neurons. This review will discuss experimental therapeutics that have been tested in murine ALS models, with an emphasis on those that have progressed to human clinical trials. …”
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The Use of Antisense-Mediated Inhibition to Delineate The Role of Inflammatory Agents in The Pathophysiology of Spinal Cord Injury by Damien D. Pearse, Francisco C. Pereira, Katina Chatzipanteli, Francisco W. Dalton Dietrich, Mary Bartlett Bunge

“…This effectively reduces the amount of corresponding translated protein product and experiments can be designed to examine the requirement of particular inflammatory agents in eliciting specific deleterious responses after injury, e.g., cell death.…”
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Variational graph autoencoder for reconstructed transcriptomic data associated with NLRP3 mediated pyroptosis in periodontitis by Pradeep K. Yadalam, Prabhu Manickam Natarajan, Carlos M. Ardila

“…The NLRP3 inflammasome triggers pyroptosis, a programmed cell death that amplifies inflammation and tissue damage. …”
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PD-1 Inhibitor Therapy in a Patient with Preexisting P-ANCA Vasculitis: A Case Report and Review of the Literature by Amanda Ramos, Marcela del Carmen, Oladapo Yeku

“…This patient received pembrolizumab, an immune checkpoint inhibitor that targets the programmed cell death-1 immune checkpoint. Ultimately, she was treated for 4 months with pembrolizumab and benefited from stable disease during this period. …”
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Selecting first-line immunotherapy in advanced melanoma: Current evidence on efficacy across diverse patient populations by Sophia Kreft, Tommaso Bosetti, Rebecca Lee, Paul Lorigan

“…Since most patients who respond to combination ipilimumab-nivolumab also respond to nivolumab-relatlimab, and many to single-agent anti-programmed death-1 (PD-1) monotherapy, the challenge is to identify the subgroup of patients who need ipilimumab-nivolumab and would not achieve similar benefits from less toxic alternatives. …”
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Systemic Amyloidosis and Cardiac Autonomic Neuropathy Associated with Waldenstrom’s Macroglobulinemia by Aasems Jacob, Rishi Raj, Warren Walkow

“…As the condition progresses, it may result in cardiac denervation which can result in silent myocardial infarction, syncope, and sudden death.…”
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Systematic Framework to Predict Early-Stage Liver Carcinoma Using Hybrid of Feature Selection Techniques and Regression Techniques by Marium Mehmood, Nasser Alshammari, Saad Awadh Alanazi, Fahad Ahmad

“…If diagnosed late, it may cause death. Treatment of liver diseases at an early stage is, therefore, an important issue as is designing a model to diagnose early disease. …”
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Enhancing hepatocellular carcinoma therapy with DOX-loaded SiO2 nanoparticles via mTOR-TFEB pathway autophagic flux inhibition by Huanyu Chen, Jun Liu, Zhichao Cao, Jiajia Li, Hong Zhang, Qianqian Yang, Jian Cheng, Yuxian Shen, Kewu He

“…Additionally, we demonstrated that the nanocarrier inhibits autophagic flux in liver cancer cells by targeting the autophagy-lysosome pathway and regulating the nuclear translocation of TFEB, thereby promoting tumor cell death. This novel diagnostic-integrated nanocarrier is expected to be a promising tool for targeted liver cancer treatment.…”
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Hemophagocytic lymphohistiocytosis following enteric fever: A rare autopsy case report by Gwendolyn Fernandes, Pooja Mhashete, Pranav Pramod Patwardhan

“…Clinically the patient was admitted for febrile illness, and treated symptomatically but his general condition worsened leading to death within 21 hours of admission. A complete autopsy was performed. …”
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County Differences in Mortality among Foreign-Born Compared to Native Swedes 1970–1999 by Björn Albin, Katarina Hjelm, Jan Ekberg, Sölve Elmståhl

“…Foreign-born persons had a lower mean age (1.0–4.3 years) at time of death. Conclusion. County of residence influences mortality; higher mortality is indicated among migrants than native Swedes in counties with a more rural structure. …”
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Accumulation of Deficits as a Proxy Measure of Aging by Arnold B. Mitnitski, Alexander J. Mogilner, Kenneth Rockwood

“…It serves as an individual state variable, reflecting severity of illness and proximity to death. In a representative database of elderly Canadians we found that deficits accumulated at 3% per year, and show a gamma distribution, typical for systems with redundant components that can be used in case of failure of a given subsystem. …”
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Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury by Phuong Chi Pham, Raghu Konanur Ventakaram, Jimmy Pham, Harpreet Sidhu, Nada Bader, Phuong Mai Pham, Phuong Thu Pham

“…Hyperphosphatemia may arise from various conditions including exogenous ingestion, extracellular shifts due to cell death or alterations in acid-base status, increased bone resorption, hormonal dysregulations leading to reduced renal excretion, reduced kidney function, or faulty measurement techniques. …”
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Platelet Responses in Cardiovascular Disease: Sex-Related Differences in Nutritional and Pharmacological Interventions by Valeria Gasperi, M. Valeria Catani, Isabella Savini

“…Cardiovascular diseases (CVD) represent one of the biggest causes of death globally, and their prevalence, aetiology, and outcome are related to genetic, metabolic, and environmental factors, among which sex- and age-dependent differences may play a key role. …”
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Studi Kasus: Implementasi Health Education Teknik Buteyko Breathing Untuk Mencegah Kekambuhan Asma Dengan Media Video Pada Keluarga by Andan Firmansyah, Muhamad Ramdan Nujulul Furqon, Daniel Akbar Wibowo, Tita Rohita

“… Asthma is a disease caused by narrowing of the airway due to inflammation or inflammation, asthma is the top 5 causes of death per year. Buteyko breathing is a deep breathing technique that is useful for strengthening the respiratory muscles. …”
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Clinical-epidemiological study on Fournier's gangrene in a Luanda hospital. From January 2016 to December 2021 by Tomas Ariel Lombardo Vaillant

“…<br /><strong>Conclusions</strong>: Fourner's gangrene is a serious disease that can present systemic repercussions and death. The cornerstone of treatment is early surgical debridement supported by support measures. …”
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The 500-year Cultural & Economic Trajectory of Tobacco: A Circle Complete by Christopher A. Jones, Amanda Wassel, William Mierse, E. Scott Sills

“…Its use in all forms represents the world’s single greatest cause of preventable disease and death. Tobacco was introduced to Europe by Christopher Columbus, who in October 1492 discovered the crop in Cuba. …”
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