Mechanism Underlying Tissue Cryotherapy to Combat Obesity/Overweight: Triggering Thermogenesis by Suvaddhana Loap, Richard Lathe

“…The current view is that acute local cooling of AT induces adipocyte cell disruption and inflammation (“cryolipolysis”) that lead to adipocyte cell death, with loss of subcutaneous fat being recorded over a prolonged period of weeks/months. …”
Get full text

Pathogenicity test bacteria from Oreochromis niloticus and Clarias gariepinus aquaculture ponds by Esti Handayani Hardi, Aldi M. Halim, Rudy Agung Nugroho, Mira Mawardi, Alim Isnansetyo, Angela Mariana Lusiastuti, Widianingsih Rahayu, Andi Niklani, Gina Saptiani

“…The result showed that each bacteria caused mortality in fish: E. coli bacteria caused fish mortality 23.33-66.67%; E. cloacae 10.00 to 90.00%; and E. amnigenus by 3.33-56.67%. The average death time of E. coli and E. amnigenus in all three fish were under 48 hours, while E. cloacae caused mortality less than 48 hours in C. gariepinus and P. pangasius. …”
Get full text

Gold Nanorod Bioconjugates for Active Tumor Targeting and Photothermal Therapy by Hadiyah N. Green, Dmitry V. Martyshkin, Cynthia M. Rodenburg, Eben L. Rosenthal, Sergey B. Mirov

“…We demonstrate that the binding efficiency of the antibodies conjugated to the PEGylated GNRs is comparable to the binding efficiency of the unmodified antibodies and 33.9% greater than PEGylated antibody-GNR conjugates as reported by Liao and Hafner (2005). In addition, cell death by NIRPTT was sufficient to kill nearly 90% of tumor cells, which is comparable to NIRPTT with GNRs alone confirming that NIRPTT using GNRs is not compromised by conjugation of GNRs to antibodies.…”
Get full text

Molecular Findings Before Vision Loss in the Streptozotocin-Induced Rat Model of Diabetic Retinopathy by Mădălina Moldovan, Roxana-Denisa Capraș, Raluca Paşcalău, Gabriela Adriana Filip

“…While redox imbalance, activation of microglia, secretion of pro-inflammatory cytokines, and neuronal cell death are also observed, the latter remains an emerging hypothesis requiring further exploration. …”
Get full text

A Novel Ferroptosis-Related Gene Signature for Prognosis Prediction in Ewing Sarcoma by Runhan Zhao, Zefang Li, Yanran Huang, Chuang Xiong, Chao Zhang, Hao Liang, Jingtao Xu, Xiaoji Luo

“…Ferroptosis, as a form of programmed cell death independent of apoptosis, has been demonstrated that plays a major role in tumorigenesis and cancer treatment. …”
Get full text

The Association Between Tei Index And Severity Of Coronary Artery Disease In Patients With Unstable Angina by Akram Shariati, Rogayeh Afsar Gharebagh, Alireza Rostamzadeh, Nazanin Sadeghifar, Nazila Pashaei, Reza Hajizadeh

“…Background and aim: Cardiovascular diseases are the main cause of death worldwide. The myocardial performance index (Tei index) is an accepted method for the evaluation of the systolic and diastolic function of the heart. …”
Get full text

Exploring TNFR1: from discovery to targeted therapy development by Yingying Li, Ruiwei Ye, Haorui Dai, Jiayi Lin, Yue Cheng, Yonghong Zhou, Yiming Lu

“…As a critical cell-surface receptor, TNFR1 regulates key signaling pathways, such as nuclear factor kappa-B (NF-κB) and mitogen-activated protein kinase (MAPK), which are associated with pro-inflammatory responses and cell death. The intricate regulatory mechanisms of TNFR1 signaling and its involvement in various diseases, including inflammatory disorders, infectious diseases, cancer, and metabolic syndromes, have attracted increasing scholarly attention. …”
Get full text

A comparative study of breast lesions using the IAC Yokohama System for reporting breast cytopathology against histopathological biopsy by Chandrakala Joshi, Ruchi Varma, Shruti Tiwari Pande

“…Background: Breast lumps pose a significant health concern globally, contributing to both illness and death. The International Academy of Cytology (IAC) Yokohama system has established a uniform method for reporting breast cytology, categorizing it into five groups: inadequate, benign, atypical, suspicious, and malignant. …”
Get full text

Eco-toxicological effects of pesticide residues on soil biological sentinels by E.I. Atuanya, T Onuoha, E Morka

“…The results also showed that earthworms had weight loss and death at different concentration of the pesticide and time of exposure, with the lethal concentration (LC50) of aldrin being 2.84mg/ml while that of lindane was 3.54mg/ml after 48hr of exposure period. …”
Get full text

Prevalence, Associated Risk Factors, and Economic Loss of Ovine Hemonchosis at Jimma Town Municipal Abattoir, Jimma Zone, Southwestern Ethiopia by Fuad Zenu Abagero, Teshita Edaso Beriso, Tilaye Shibbiru Mengistu

“…Hemonchosis is considered one of the most severe gastrointestinal parasitic diseases in small ruminants due to the blood feeding habits of the parasites, which results in production loss and death of the animals. A cross-sectional study was conducted from December 2022 to March 2023 at the Jimma town municipal abattoir with the objectives of estimating the occurrence of ovine hemonchosis, investigating potential associated risk factors, and assessing economic loss due to the disease. …”
Get full text

Correlation between T-Wave Alternans and Cardiac Volume Status via Intrathoracic Impedance Measurements by Jose' Dizon, Kathleen Hickey, Hasan Garan

“…The presence of T-wave alternans (TWA) has been shown to correlate with a higher risk for sudden cardiac death. The mechanism of TWA may be related to abnormalities in intracellular calcium handling, which is a mechanism in heart failure and associated arrhythmias as well. …”
Get full text

Do Pathologic Fractures in Long Bone Following Bony Malignancy Increase the Risk of Venous Thromboembolism? A Comparative Study by Sanjay Kumar Rai, Tej Pratap Gupta, Bhavya Sirohi, Surbhi Rajauria, Nitish Khandelwal

“…Conclusion: Patients with a pathological long bone fracture who underwent surgical management are at greater risk for DVT or death due to pulmonary embolism under the current recommended thromboprophylaxis protocol. …”
Get full text

The Role of Air Pollution and Olfactory Dysfunction in Alzheimer’s Disease Pathogenesis by Louise Odendaal, Hazel Quek, Carla Cuní-López, Anthony R. White, Romal Stewart

“…AD is recognised for its characteristic deposition of toxic proteins within the brain, leading to a steady deterioration of cognitive capabilities, memory failure, and, ultimately, death. There is burgeoning evidence implying that air pollution may be a contributing factor to this protein build up, thereby intensifying the course of AD. …”
Get full text

Time to be seen and heard: Including children’s and adolescents’ voices in the South African TB response by C Goslett, K du Preez, G Hendricks, A Best

“…Children are particularly vulnerable to TB infection and to dangerous forms of disseminated TB such as TB meningitis, which can cause death or major lifelong disability. They have distinct challenges with diagnosis, and TB treatment for adults is not necessarily child- friendly. …”
Get full text

Risk Factor-Specific Mortality Analysis of the Outborn Newborns to Improve the Neonatal Mortality Rate: A Cross-Sectional Descriptive Study by Tapan K. Kundu, Abhilash Chatterjee, Mitali Bera, Aditi Chowdhury, Riya Guchhait

“…The 2030 Sustainable Development Goal (SDG) envisions eliminating preventable newborn deaths and reducing neonatal mortality to 12 per 1000 live births. …”
Get full text

Inflammation and Inflammasomes: Pros and Cons in Tumorigenesis by Liliana R. Balahura, Aida Selaru, Sorina Dinescu, Marieta Costache

“…The function of this multiprotein complex is not only to reassure inflammation and to promote cell death, through caspase activity, but also has been identified to have significant contributions during tumorigenesis and cancer development. …”
Get full text

Normative Provision of Personal Safety of the Employees of the National Police of Ukraine by Sklyar О. S. Sklyar, T. V. Shevchenko

“…In accordance with the Law of Ukraine “On the National Police” and in order to ensure the personal safety of police officers and to prevent the death, injury and trauma of them and others during the handling of weapons, the Minister of Internal Affairs of Ukraine approved the Instruction on security measures when handling weapons, which is only a part of the official activities of police agencies (institutions, organizations) and does not reveal the essence of the content of personal safety. …”
Get full text

Stroke Lesion Prediction by Bille-Viper-Segmentation with Tandem-MU-net Model by Beevi Fathima, N Santhi Dr, N Ramasamy Dr

“…Stroke is a critical condition marked by the death of brain cells due to inadequate blood flow, necessitating improved predictive models for stroke lesions. …”
Get full text

Temporal and Spatial Pattern of Pulmonary Tuberculosis in Gansu Province and Its Environmental Factors Detection and Analysis by Haili Zhao, Jun Wang, Minghui Wu

“…As one of the major public health security issues, pulmonary tuberculosis had a global death rate of 1.6 million in 2021 alone, ranking 13th in the world, posing a great threat to society and families. …”
Get full text

A standardized physician-modified endograft workflow utilizing the punch card technique and the Hungaroring reinforcement to treat complex abdominal aortic aneurysms by Csaba Csobay-Novák, MD, PhD, Bendegúz Juhos, PhD, András Szentiványi, MD, Ákos Bérczi, MD, PhD, Artúr Hüttl, MD, Péter Sótonyi, MD, DSc

“…No major adverse event or death was recorded at 30 days. The punch card and the novel reinforcement technique might improve the safety and durability of such repairs.…”
Get full text