Multi-assay assessment of cytotoxicity reveals multiple mechanisms of action in 3D microtissues by Ahbid Zein-Sabatto, Katerina St. Angelo, Samantha J. Madnick, Diane Hoffman-Kim, Jeffrey R. Morgan, Jonghwan Lee

“…Abstract Cell viability assays are an integral component of toxicology and high-throughput drug screening studies; however, many assays rely on a single biomarker of cell death which provides an incomplete assessment of cell viability. …”
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The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment by Yi-Cheng Chang, Siow-Wey Hee, Meng-Lun Hsieh, Yung-Ming Jeng, Lee-Ming Chuang

“…Specifically, excessive nutrients trigger endoplasmic reticulum stress and increase the production of mitochondrial reactive oxygen species, leading to activation of stress signaling pathway, inflammatory response, lipogenesis, and pancreatic beta-cell death. Autophagy is required for clearance of hepatic lipid clearance, alleviation of pancreatic beta-cell stress, and white adipocyte differentiation. …”
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Singularity, violence and universality in Derrida’s ethics: Deconstruction’s struggle with decisionism by Stocker Barry

“…This theme develops into an examination of mass slaughter around the Hebrew Bible story of the “shibboleth”, highlighting the violent consequences of exclusionary conceptions of identity. In The Gift of Death, Derrida discusses the relationship between Paganism, Platonism, and Christianity through Patočka’s perspective, then returns to Judaism via Kierkegaard’s discussion of Abraham and Isaac. …”
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Unusual Infections Complicating the Use of Steroids with Severe Alcoholic Hepatitis: Report of 2 Cases by Vitor Arantes, Pina Michieletti, Ross Cameron, Jenny Heathcote, Morris Sherman

“…Despite surgical debridement the lesion progressed and contributed to her death. Treatment of alcoholic hepatitis with steroids is not innocuous, and physicians should be aware of the potential for life-threatening complications.…”
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La peur dans The City of Dreadful Night (1874) de James Thomson by Françoise Dupeyron-Lafay

“…And in this doomed world, the most frightening thing is not so much death as life...…”
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Acquired Myelodysplasia or Myelodysplastic Syndrome: Clearing the Fog by Ethan A. Natelson, David Pyatt

“…They are typically considered neoplasms because of frequent genetic aberrations and patient-limited survival with progression to acute myeloid leukemia (AML) or death related to the consequences of bone marrow failure including infection, hemorrhage, and iron overload. …”
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CCN1 promotes APRIL/BAFF signaling in esophageal squamous cell carcinoma but attenuates it in esophageal adenocarcinoma by Lingling Xing, Zhenyu Jiang, Ruize Xu, Tong Dang, Jinbao Wu, Jianyuan Chai, Xianmei Meng

“…Unlike TRAIL, which primarily triggers cell death, APRIL and BAFF promote cell growth via NFκB signaling. …”
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PEDIATRIC ENTEROCOLITIS: CLINICAL MANIFESTATIONS AND MANAGEMENT STRATEGIES by Ginel Baciu, Carmen Baciu, Cristina Maria Mihai, Tatiana Chisnoiu, Ramona Mihaela Stoicescu, Adriana Luminita Balasa, Adriana Mocanu, Lorenza Forna, Alexandru Paul Baciu

“…Diarrhea is a leading cause of illness and death in children under five years old. Severe cases of diarrhea, particularly those resulting in dehydration, are a major factor in high mortality rates. …”
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Non-useful Papanicolaou smears. Analysis of their causes in the first semester 2005 in Cienfuegos city, Cuba by Miryam Magalys González González del Pino, Teresita Sabatés Llerandi, Mayrim Hernández González

“…It is one of the three main death causes in women after breast and colon cancer. …”
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Tuberculosis in Pregnancy: A Review by Olabisi M. Loto, Ibraheem Awowole

“…The disease is a significant contributor to maternal mortality and is among the three leading causes of death among women aged 15–45 years in high burden areas. …”
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An Overview of the BALSAC Population Database. Past Developments, Current State and Future Prospects by Hélène Vézina, Jean-Sébastien Bournival

“…Coverage is complete for Catholic records (80 to 100% of the population depending on the region and the period) and partial for the other denominations. Birth and death certificates from all Catholic parishes have been integrated for the period 1800–1849 and work in underway for 1850–1916. …”
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Chlorogenic acid complex (CGA7), standardized extract from green coffee beans exerts anticancer effects against cultured human colon cancer HCT-116 cells by K. Gouthamchandra, H.V. Sudeep, B.J. Venkatesh, K. Shyam Prasad

“…From our results we found CGA7 treatment induces cell death in a dose and time dependent manner in different cancer cell lines. …”
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Consummatio gloriae – zapomniany Tomaszowy motywwcielenia Chrystusa w świetle ST II-II, q.2, a.7 by Piotr Świerczyński

“…In ST this clear knowledge is only about this aspect of Incarnation mystery, with is linked with Consummatio gratiae; the first man didn’t know about passion and death of Christ, because he couldn’t know about his own sin in future: their reason. …”
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Investigation of the Views of Biology Teachers on Distance Education during the COVID-19 Pandemic by Ferhat Karakaya, Selcuk Arik, Osman Cimen, Mehmet Yilmaz

“…Coronavirus disease has caused the death of many people since its first identification in Wuhan, China, in December 2019. …”
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Two cases of complex traumatic aortic dissection combined with multiple organ injuries by Qingpeng Song, Lili Bao, Xuejun Wu, Bingqi Liu, Maohua Wang

“…TAI progresses very rapidly, with a pre-hospital mortality rate of 57%–80%, and even when arriving at the hospital, more than one-third of the patients die within 4 h, and it is the 2nd leading cause of death in individuals aged 4−34 years. In addition, the incidence of TAI combined with injury was 81.4%. …”
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Brain-Derived Neurotrophic Factor and Nerve Growth Factor Therapeutics for Brain Injury: The Current Translational Challenges in Preclinical and Clinical Research by Serena-Kaye Sims, Brynna Wilken-Resman, Crystal J. Smith, Ashley Mitchell, Lilly McGonegal, Catrina Sims-Robinson

“…Ischemic stroke and traumatic brain injury (TBI) are among the leading causes of death and disability worldwide with impairments ranging from mild to severe. …”
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Rationale for the Use of Cord Blood in Hypoxic-Ischaemic Encephalopathy by Izabela Zdolińska-Malinowska, Dariusz Boruczkowski, Dominika Hołowaty, Paweł Krajewski, Emilian Snarski

“…In several animal models of HIE, CB decreased oxidative stress, cell death markers, CD4+ T cell infiltration, and microglial activation; restored normal brain metabolic activity; promoted neurogenesis; improved myelination; and increased the proportion of mature oligodendrocytes, neuron numbers in the motor cortex and somatosensory cortex, and brain weight. …”
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Update on Babesiosis by Edouard Vannier, Peter J. Krause

“…The severity of infection ranges from asymptomatic infection to fulminant disease resulting in death, although the majority of healthy adults experience a mild-to-moderate illness. …”
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Breast Cancer. A Characterization in the Decade from 1996-2005. by Lidia Torres Ajá, Julio César Sarmiento Sánchez, Arístides Sánchez Sánchez, Otto Pacheco Ruiz, Nancy Capin Sarría, Práxedes Rojas Quintana

“…<p><strong>Background:</strong> Breast Cancer constitutes a health problem in Cuba due to it is the first cause and localization of death for malignant tumors in females. This situation has been considered by our health Minister as a number one priority of investigation. …”
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Rational Suicide, Euthanasia, and the Very Old: Two Case Reports by Anne Pamela Frances Wand, Carmelle Peisah, Brian Draper, Carolyn Jones, Henry Brodaty

“…Palliative care models promote best care as holistic and relieving suffering without hastening death in severely ill patients; but what of those old people who are tired of living and may have chronic symptoms, disability, and reduced quality of life? …”
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