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2421
Good Worker Health and Hygiene Practices: Evaluation and Importance in GAPs and GMPs
Published 2004-12-01“…Young children, the elderly, and people with immuno-compromising conditions such as HIV, AIDS, and cancer run even greater risk of serious illness or death related to contaminated foods. Therefore, it is now more important than ever that everyone involved in handling food uses recommended sanitation practices. …”
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2422
Spindle Bursts in Neonatal Rat Cerebral Cortex
Published 2016-01-01“…Disturbances in spindle burst activity during corticogenesis may contribute to disorders in cortical architecture and in the activity-dependent control of programmed cell death. In this review we discuss (i) the functional properties of spindle bursts, (ii) the mechanisms underlying their generation, (iii) the synchronous patterns and cortical networks associated with spindle bursts, and (iv) the physiological and pathophysiological role of spindle bursts during early cortical development.…”
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2423
Treatment of oligometastatic breast cancer: The role of patient selection
Published 2025-02-01“…Up to 90 % of death from solid tumors are caused by metastases. …”
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2424
Colon cancer surgery. Five years of experience.
Published 2004-12-01“…In spite of the advances in the last few years in regards to treatment, colon cancer is the most frequent cause of death due to cancer. <strong>Objective</strong>: To know morbimortality due to cancer of the colon after both, surgery and oncological treatment. …”
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2425
Structured Teaching Programme on Knowledge Regarding Management of Obstructed Labor Among Final Year GNM Students
Published 2025-01-01“…Obstructed labour is the single most important cause of maternal death and is one of the three leading causes of perinatal mortality with a case fatality rate ranging between 87-100. …”
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2426
Size, shape, and dose — three crucial determinants for applying nanoparticles in sustainable plant biology
Published 2024-09-01“…In contrast, negative effects include germination retardation, growth inhibition, cell impairment, deterioration, and eventually death. Different outcomes depend on factors such as plant species, the physicochemical nature of the NP, NP size, shape, and concentration, and the type of medium. …”
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2427
Recognition of a Drowning Victim by Bystanders: A Scoping Review
Published 2022-07-01“…Background: Globally, drowning is one of the leading causes of unintentional death. Whilst the World Health Organization (WHO) has identified that bystanders could play an important role in decreasing drowning deaths, few studies have evaluated whether bystanders can recognize a drowning victim. …”
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2428
Mitochondria as a Therapeutic Target: Focusing on Traumatic Brain Injury
Published 2025-01-01“…Mitochondria are organelles of eukaryotic cells delimited by two membranes and cristae that consume oxygen to produce adenosine triphosphate (ATP), and are involved in the synthesis of vital metabolites, calcium homeostasis, and cell death mechanisms. Strikingly, normal mitochondria function as an integration center between multiple conditions that determine neural cell homeostasis, whereas lesions that lead to mitochondrial dysfunction can desynchronize cellular functions, thus contributing to the pathophysiology of traumatic brain injury (TBI). …”
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2429
Sleep in Chronic Obstructive Pulmonary Disease: Evidence Gaps and Challenges
Published 2016-01-01“…People with obstructive sleep apnea (OSA) plus COPD (the so-called overlap syndrome) have a high risk of cardiovascular death, although again mechanisms are unknown and untested. …”
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2430
Role of astrocytes connexins - pannexins in acute brain injury
Published 2025-01-01“…However, after acute brain injury, astrocytes can change their phenotype and modify the activity of both channels and hemichannels, which can result in the amplification of danger signals, increased mediators of inflammation, and neuronal death, contributing to the expansion of brain damage and neurological deterioration. …”
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2431
ROLE OF HETEROZYGOUS TUMOR SUPPRESSORS IN THE LIFE LONGEVITY OF DROSOPHILA MELANOGASTER
Published 2015-01-01“…The analysis of Gompertz curve parameters indicates that the l(3)hem, hyd or gd mutations increase age-related parameter (α) in males, while gd mutation increases the death background parameter (R) and the ex agerelated parameter in females. …”
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2432
Effects of an Aquatic Physical Exercise Program on Ventilatory Parameters in People with Parkinson’s Disease
Published 2022-01-01“…Problems in the respiratory system are the main cause of death in Parkinson’s disease (PD). Ventilatory limitations can also be part of a vicious cycle involving physical-functional limitations (e.g., walking difficulties) and the patients’ perception of fatigue. …”
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2433
Left Ventricle Segmentation in Cardiac MR Images via an Improved ResUnet
Published 2022-01-01“…Cardiovascular diseases are reported as the leading cause of death around the world. Automatic segmentation of the left ventricle (LV) from magnetic resonance (MR) images is essential for an early diagnosis. …”
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2434
A Hypothesis Concerning a Potential Involvement of Ceramide in Apoptosis and Acantholysis Induced by Pemphigus Autoantibodies
Published 2010-01-01“…Our hypothesis is that: (1) the autoantibodies generate pathology through an alteration in ceramide metabolism in targeted keratinocytes, resulting in apoptosis and/or cell death and acantholysis, but only when the cell's ability to metabolize ceramide is exceeded, and (2) apoptosis in response to this altered ceramide metabolism is initiated and/or exacerbated by other agents that increase ceramide levels, such as cytokines, ultraviolet irradiation, and senescence.…”
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2435
Measurement of Quality of Life VI. Quality-Adjusted Life Years (QALY) is an Unfortunate Use of the Quality-of-Life Concept
Published 2003-01-01“…The problem of priorities may then turn out to be far more simple and also more ethical: the focus will be on the quality of life, not on QALY, and the question of the meaning of life and death will achieve greater openness and respect.…”
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2436
Sudden Cardiac Arrest in a Youth with Multiple Arrhythmic Substrates
Published 2024-01-01“…Despite being relatively common, the clinical significance of MAD is still uncertain and the extent to which it may be linked with complications such as ventricular arrhythmias and sudden cardiac death. MAD appears to confer an increased risk of ventricular arrhythmias, particularly when associated with MVP, particularly nonsustained VT.…”
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2437
Recommendations for Control and Mitigation of Laurel Wilt and Ambrosia Beetle Vectors in Commercial Avocado Groves in Florida
Published 2020-03-01“… The lethal laurel wilt epidemic affecting avocado trees in Florida is caused by a fungal pathogen-ambrosia beetle complex (LW-AB). The death of over 120,000 commercial avocado trees in Florida may be attributed to LW-AB. …”
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2438
Pseudomonas Aeruginosa and Cystic Fibrosis: Antibiotic Therapy and the Science behind the Magic
Published 1997-01-01“…Respiratory failure secondary to chronic bronchiectasis is the cause of death in more than 90% of patients with cystic fibrosis (CF). …”
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2439
Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology and S-(De)nitrosylation: Implications in Cancer and Neurodegeneration
Published 2012-01-01“…In this paper we aim at summarizing the current knowledge of mitochondria-related proteins undergoing S-nitrosylation and how this redox modification might impact on mitochondrial functions, whose impairment has been correlated to tumorigenesis and neuronal cell death. In particular, emphasis will be given to the possible, but still neglected implication of denitrosylation reactions in the modulation of mitochondrial SNOs and how they can affect mitochondrion-related cellular process, such as oxidative phosphorylation, mitochondrial dynamics, and mitophagy.…”
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2440
Invasive Microascus trigonosporus Species Complex Pulmonary Infection in a Lung Transplant Recipient
Published 2015-01-01“…Despite this apparent improvement, the patient’s pulmonary status progressively declined in the setting of multiple comorbidities, ultimately leading to respiratory failure and death.…”
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