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4941
Composition of the sputum bacterial microbiome of patients with different pathomorphological forms of non-small-cell lung cancer
Published 2024-04-01“…Such microbiome changes may include the occurrence of bacteria that cause oxidative stress and that are capable of causing genome damage in the cells of the host organism directly and indirectly. To date, the composition of the respiratory microbiome in patients with various histological variants of lung cancer has not been studied. …”
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4942
Prior Appendectomy and the Onset and Course of Crohn’s Disease in Chinese Patients
Published 2019-01-01“…Appendectomies were performed closer to the date of CD diagnosis in the trend test (P=0.039). …”
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4943
RHOBTB2 Variant p.Arg511Gln Causes Developmental and Epileptic Encephalopathy Type 64 in an Infant: A Case Report and Hotspot Variant Analysis
Published 2025-01-01“…Genetic analysis revealed a de novo variant in RHOBTB2, c.1532G>A, p.(Arg511Gln). To date, 60 cases of DEE patients with RHOBTB2 variants have been reported, with approximately 50% of variants located at Arg483 and Arg511. …”
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4944
Improved Antibacterial Activity of Water-Soluble Nanoformulated Kaempferol and Combretastatin Polyphenolic Compounds
Published 2021-01-01“…No studies have been performed to date using nanoformulations of kaempferol and combretastatin to investigate their roles. …”
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4945
Clinical Characteristics of Paracentral Acute Middle Maculopathy in Eyes with Retinal Vascular Occlusion Diseases in Chinese Patients
Published 2021-01-01“…This series is the largest to date to describe the clinical characteristics of PAMM and p-MLM sign in Chinese patients. …”
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4946
The creation and characterization of the bread wheat line with a centric translocation T2DL.2RL
Published 2019-11-01“…The development of bread wheat introgressions with alien genetic material from cultural and wild Triticeae species is an effective method for expanding the wheat gene pool necessary for breeding. To date, numerous collections of introgressions as substitutions and chromosome modifications have been obtained; however, the creation and study of wheat with new valuable traits still remain an important line of research. …”
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4947
Analysis of Mortality and Survival Rate of Liver Cancer in Zhejiang Province in China: A General Population-Based Study
Published 2019-01-01“…Background. Few accurate up-to-date studies provide liver cancer mortality and survival information in Zhejiang province. …”
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4948
Effectiveness of Retail Promotions in the Green Industry by Age Group: A Case Study
Published 2020-03-01“…The local and ‘grow your own food’ movements are likely the main drivers of increased interest in edible and food producing plants (National Gardening Association, 2013). To date, research addressing retail promotions in the green industry by age segments has not been adequately addressed. …”
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4949
Successful open defecation-free intervention in low- and middle-income countries: a qualitative synthesis systematic review protocol
Published 2025-01-01“…This systematic review did not impose any restrictions on the place and date of publication. Two reviewers followed Joanna Briggs Institute guidelines in selecting studies, conducting critical appraisal using confidential tools and extracting data using a structured approach. …”
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4950
THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY
Published 2021-08-01“…The outbreak of the COVID-19 infection caused by the new coronavirus SARS-CoV-2 is one of the most significant and dangerous challenges of our time. To date, there is a decrease in the number of cases per day, but there is a variety in the course of the disease depending on sex, and the most vulnerable are elderly patients with comorbid pathology, therefore, the study of its features determines the relevance of this work. …”
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4951
STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn’s Disease
Published 2019-01-01“…The accumulation of IFN-γ-producing ILC1s and increased level of proinflammatory cytokines produced by ILCs has been observed in the inflamed terminal ileum of CD patients. To date, the precise mechanisms of ILC plasticity and gene regulatory pathways in ILCs remain unclear. …”
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4952
A 5.5–7.5‐GHz band‐configurable wake‐up receiver fully integrated in 45‐nm RF‐SOI CMOS
Published 2022-10-01“…To the authors' best knowledge, this work offers the largest RF bandwidth from 5.5 to 7.5 GHz, the most operation channels (≥8) and the fastest settling time (<115 ns) among the WuRXs reported to date.…”
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4953
Occupational Infections Among Workers in Europe: Protocol for a Scoping Review
Published 2025-01-01“…Such findings could improve the understanding of this complex occupational phenomenon in the European context, enabling more accurate and up-to-date surveillance of infections incurred in the workplace. …”
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4954
Green tourism business as marketing perspective in environmental management
Published 2022-10-01“…Strategic marketing support of green tourism development in Ukrainian regions was defined based on ecological and marketing strategies.CONCLUSION: The author's approach makes it possible to systematically assess the potential of green tourism using up-to-date statistical information. According to the tourism and environmental competitiveness rating, the regions with the most significant and worst potential were found. …”
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4955
Impact of the Clinical Trials Act 2018 on clinical trial activity in Japan from 2018 to 2020: a retrospective database study using new and conventional Japanese registries
Published 2022-07-01“…We collected and analysed information on registration dates, intervention types, funding, secondary sponsors and use of designated staff in multidisciplinary roles (research planning support, research administration, data management, statistical analysis, monitoring and auditing). …”
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4956
Impact of handgrip strength on cardiovascular, cancer and all-cause mortality in the Korean longitudinal study of ageing
Published 2019-05-01“…The cause-specific hazards regression analysis was also used to model cardiovascular and cancer mortality, by treating deaths from the cause of interest as events and other causes of death as censored.Participants 5859 participants aged 50 years or older were followed up until death or until the date of censoring (31 December 2014).Primary outcome measures The study outcomes of interest were all-cause, cardiovascular and cancer mortality.Results Of the participants included in analyses, 515 individuals (8.8%) died, reflecting an overall crude mortality rate of 11.0 deaths per 1000 person-years. …”
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4957
Investigation of Information Overload in Electronic Health Records: Protocol for Usability Study
Published 2025-02-01“…The study was initiated in 2022 with a completion date of 2025. Data collection for this study was completed in December 2023 and data analysis is ongoing with a total of 81 provider sessions recorded. …”
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4958
Medical thoracoscopy combined with intrapleural injection of urokinase for treatment of pleural infection-a multicenter, prospective, randomized controlled study: study protocol
Published 2025-01-01“…Registration number ChiCTR2300078352 (Registration Date: 2023/12/06).…”
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4959
Epigene functional diversity: isoform usage, disordered domain content, and variable binding partners
Published 2025-02-01“…Despite their importance to human disease, to date, there has not been a systematic analysis of the sources of functional diversity for epigenes at large. …”
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4960
Decreased Hospital Length of Stay for ICH and PE after Adoption of an Artificial Intelligence-Augmented Radiological Worklist Triage System
Published 2022-01-01“…Pre-AI and post-AI time periods were defined around the deployment dates of the ICH and PE modules, respectively. The reduction in LOS was 1.30 days (95% C.I. 0.1–2.5), resulting in an observed percentage decrease of 11.9% (p value = 0.032), for ICH and 2.07 days (95% C.I. 0.1–4.0), resulting in an observed percentage decrease of 26.3% (p value = 0.034), for PE when comparing the pre-AI and post-AI time periods. …”
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