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4561
Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model
Published 2019-01-01“…However, disruption of the AIS structure is linked to the etiology of multiple disorders, including autism spectrum disorder (ASD), a condition characterized by deficits in social communication, stereotyped behaviors, and very limited interests. To date, a complete understanding of the molecular components that underlie the AIS in ASD has remained elusive. …”
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4562
Evaluation of fertilization strategies for the establishment and productivity of Xaraés grass
Published 2024-11-01“…In the second, a 3 × 10 factorial scheme was used, corresponding to the three establishment fertilization strategies and 10 evaluation dates (32, 39, 46, 53, 60, 67, 74, 81, 88, and 95 days) after emergence. of plants (DAE). …”
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4563
Length of stay after colorectal surgery in Italy: the gap between “fit for” and “actual” discharge in a prospective cohort of 4529 cases
Published 2025-02-01“…Methods All patients enrolled in the prospective iCral3 study were analyzed regarding any difference and reason between the “fit for discharge” (FFD) and “actual discharge” (AD) dates. The association between the gap and the LOS in the whole population was then assessed through a multivariate regression model including other confounding variables. …”
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4564
Negative Effects of High Glucose Exposure in Human Gonadotropin-Releasing Hormone Neurons
Published 2013-01-01“…Among metabolic factors hyperglycemia has been implicated in the control of the reproductive axis at central level, both in humans and in animal models. To date, little is known about the direct effects of pathological high glucose concentrations on human GnRH neurons. …”
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4565
Time-course of antipredator behavioral changes induced by the helminth Pomphorhynchus laevis in its intermediate host Gammarus pulex: the switch in manipulation according to parasi...
Published 2023-11-01“…However, the whole time-course of this sequence of behavioral switch is not yet known, and only one antipredator behavior has been studied to date. Here we show that the protective part of this manipulation begins quite late during the parasite ontogeny, suggesting that the advantages overpass the costs induced by this protective manipulation only at this stage. …”
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4566
Safety and Biodistribution of an Autologous Bone Marrow-Derived Mononuclear Cell Infusion into Renal Arteries in Patients with Focal Segmental Glomerulosclerosis: A Phase 1 Study
Published 2024-01-01“…The safety of systemic administration of bone marrow-derived mononuclear cells (BMDMCs) has been shown in different preclinical models of kidney diseases. However, to date, no study has evaluated the safety and biodistribution of BMDMCs after infusion in renal arteries in patients with FSGS. …”
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4567
Exploiting venom toxins in paratransgenesis to prevent mosquito-borne disease
Published 2025-01-01“…However, the only toxins to be explored in mosquito paratransgenesis to date are scorpine and mutated phospholipase A2. To enhance the scope, effectiveness and durability of paratransgenesis, an expanded arsenal of effectors is required. …”
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4568
Intrinsically anisotropic 1D NbTe4 for self-powered polarization-sensitive photodetection
Published 2024-11-01“…NbTe4, a quasi-1D transition metal tetra-chalcogenide, offers significant benefits for polarization-sensitive photodetection due to its structural anisotropy. Nonetheless, to date, the anisotropic properties of 1D NbTe4 have not been reported. …”
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4569
Prenatal Diagnosis of Complete Atrioventricular Septal Defect: Perinatal and Neonatal Outcomes
Published 2009-01-01“…Of the 22 live births, 5 were neonatal deaths without surgery while 17 babies underwent surgery and 13 have survived to date. The mean survival age was 53±4 months (range 22–64 m). …”
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4570
Prehabilitation during neoadjuvant therapy in patients with cancer of the upper gastrointestinal tract and rectum—the study protocol
Published 2025-02-01“…Primary outcomes include: the percentage of patients interested in participating in the study out of all patients indicated for neoadjuvant therapy at University Hospital Ostrava during the observed period, the percentage of patients who complete the prehabilitation programme until the date of surgery and individual patient compliance. …”
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4571
Geographical distribution of eight neuromuscular disorders in the Netherlands based on a nationwide registry
Published 2025-01-01“…The variables used were diagnosis, date of diagnosis, and the first two digits of the postal code for geographical location from CRAMP. …”
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4572
Very Small Embryonic-Like Stem Cells, Endothelial Progenitor Cells, and Different Monocyte Subsets Are Effectively Mobilized in Acute Lymphoblastic Leukemia Patients after G-CSF Tr...
Published 2018-01-01“…ALL chemotherapy is associated with numerous side effects including neutropenia that is routinely prevented by the administration of growth factors such as granulocyte colony-stimulating factor (G-CSF). To date, the effects of G-CSF treatment on the level of mobilization of different stem and progenitor cells in ALL patients subjected to clinically effective chemotherapy have not been fully elucidated. …”
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4573
The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario
Published 2016-01-01“…There are no Canadian prevalence studies on pulmonary arterial hypertension (PAH) to date. We described the characteristics of treated PAH patients and the healthcare utilization and costs associated with PAH in a population of public drug plan beneficiaries in Ontario, Canada. …”
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4574
Bibliometric analysis of photodynamic research in bladder cancer: Trends and future directions
Published 2025-04-01“…Methods: Retrieving bibliographies from the Web of Science Core Collection limited the publication date to December 31, 2023, from January 1, 2004. …”
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4575
Effects of exogenous selenium application on quality characteristics, selenium speciation, and in vitro bioaccessibility of rice pancakes
Published 2025-01-01“…Selenium is an essential trace element for human health. To date, a hotspot of functional foods is strengthening the content of organic Se in food using biological Se enrichment. …”
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4576
Comprehensive Assessment of Specific Patient-Reported Outcome Measures for Hand and Wrist Conditions in Adults: A Scoping Review
Published 2025-03-01“…The objective is to provide healthcare professionals with an up-to-date overview of the available PROMs, empowering them to make informed decisions in selecting the most appropriate PROM to support personalized care for their patients. …”
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4577
Complete Genome Sequence Analysis of the First Imported Mpox Virus Clade Ib Variant in China
Published 2025-01-01“…In contrast, the more pathogenic and clinically severe MPXV clade Ib has been relatively rare, with no reports in China to date. Here, we analyzed the whole gene sequence of imported MPXV clade Ib variant from the first infection case detected in China. …”
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4578
Joint Effect of Maternal Tobacco Smoking and Pregestational Diabetes on Preterm Births and Congenital Anomalies: A Population-Based Study in Northern Italy
Published 2018-01-01“…Smoking and pregestational diabetes (PGD) are recognized risk factors for adverse pregnancy outcomes, but to date, no population-based study has investigated their joint effects. …”
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4579
Characteristics of microbial contamination of animal raw materials and products in the Russian Federation from 2015 to 2018
Published 2020-03-01“…To date, there is a whole system of legal documents, regulating food security issues in the Russian Federation. …”
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4580
The mitochondrial gene order and CYTB gene evolution in insects
Published 2017-05-01“…Mitochondrial DNA genes (mtDNA) are quite often used as markers for phylogenetic research into many organisms including arthropods, because mtDNA is multicopied, is inherited maternally, does not undergo recombination and accumulates mutations quickly enough (relative to the nuclear genome). To date, a large number of full nucleotide sequences of mitogenomes (thousands of organisms) has been deposited in public databases; however, their phylogenetic analysis has obstacles, especially for representatives of the insects (Insecta), whose evolution takes a considerable part of geological time. …”
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