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  1. 4521

    Genomic and transcriptomic insights into vitamin A-induced thermogenesis and gene reuse as a cold adaptation strategy in wild boars by Mingpeng Zhang, Aleksei Traspov, Jiawen Yang, Min Zheng, Veronika R. Kharzinova, Huashui Ai, Natalia A. Zinovieva, Lusheng Huang

    Published 2025-01-01
    “…We constructed the most comprehensive wild boar whole-genome variant dataset to date, comprising 124 samples from tropical to frigid zones, among which 47 Russian, 8 South Chinese and 3 Vietnamese wild boars were newly supplemented. …”
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  2. 4522

    Impact of a synchronous prophylactic treatment of the anterior accessory saphenous vein on the recurrent varicose vein rate in patients undergoing thermal ablation of an insufficie... by Lorenz Uhlmann, Christine Fink, Karsten Hartmann, Thomas Mattausch, Hans-Christian Wenzel, Phillip Zollmann, Jürgen Veltman, Thomas Weiler, Guido Lengfellner, Lars Müller, Markus Stücker, Felizitas Pannier, Carmen Dietrich, Tobias Hirsch

    Published 2022-06-01
    “…Introduction To date, there are no prospective studies evaluating the prevention of recurrent veins by the simultaneous treatment of a sufficient anterior accessory saphenous vein (AASV) in patients undergoing endovenous laser ablation (EVLA) of an insufficient great saphenous vein (GSV). …”
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  3. 4523

    The Impact of Physical Activities on Male Fertility: A Systematic Review by Albert Kapla, Alicja Černohorská, Daria Bednarczyk, Julia Białeta, Karolina Siembab, Katarzyna Rowińska, Michalina Jurkiewicz, Wiktor Garbarczyk, Wiktoria Pysiewicz, Agnieszka Napieralska

    Published 2025-02-01
    “…The collected data were analyzed and synthesized to provide an up-to-date overview of the topic. Conclusion The authors argue that the generally positive impact of exercise on male fertility can be demonstrated on many levels. …”
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  4. 4524

    Efficient degradation of neomycin by Bacillus velezensis and Cupriavidus basilensis isolated from mangrove soil and pharmaceutical wastewater by Qian Yang, Wenzhuan Huang, Xue Yan, Qiang Ding, Jiaxin Liu, Bo Cheng, Tao Duan

    Published 2025-01-01
    “…Biodegradation is a key pathway for the removal of neomycin from the environment. To date, only the white-rot fungus Trametes versicolor and the ericoid mycorrhizal fungus Rhizoscyphus ericae have been documented to efficiently degrade neomycin. …”
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  5. 4525

    Linking Complement C3 and B Cells in Nasal Polyposis by Ulrike Werner, Axel Künstner, Maren Drenckhan, Ralph Pries, Karl-Ludwig Bruchhage, Hauke S. Busch, Claus Bachert, Barbara Wollenberg

    Published 2020-01-01
    “…Dysregulated complement activation may contribute to immunologic alterations and disease. To date, there is only scattered knowledge on the source and regulation of the central complement factors in the pathogenesis of nasal polyps. …”
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    Article
  6. 4526

    Efficacy and safety of high-voltage versus standard-voltage pulsed radiofrequency ablation for patients with neuropathic pain: protocol for a systematic review and meta-analysis by Zheng Wang, Yitong Jia, Yanhui Ma, Tengteng Wang, Kunpeng Feng, Guang Feng, Tianlong Wang

    Published 2022-07-01
    “…This study aims to compare the efficacy and safety of high-voltage PRF ablation and standard-voltage PRF ablation for the treatment of patients with NP.Methods and analysis We will search PubMed/MEDLINE, EMBASE, Web of Science, the Cochrane Library, conference proceedings for relevant abstracts, clinical trials registers (ClinicalTrials.gov) and the WHO’s International Clinical Trial Registry Platform (from the date of inception until 15 March 2022). Only randomised controlled trials will be included. …”
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  7. 4527

    THE NATIONAL ONCOLOGICAL PROGRAM IMPLEMENTATION – EXPERIENCE IN THE VLADIMIR REGION (TO THE 70TH ANNIVERSARY OF THE REGIONAL CLINICAL ONCOLOGICAL DISPENSARY) by A. G. Zirin, E. A. Rumyantseva, K. V. Chirkov, M. N. Bulanov, G. V. Shatalova, Yu. L. Timofeev, A. V. Basharin, I. A. Konyukhov, A. V. Sheiko

    Published 2017-03-01
    “…They are: Increase of 5-year survival value of patients with malignant tumors after diagnosis date to 51.4%; Increase the number of malignant tumors early detection cases at the I–II stages up to 51%; Decrease the mortality rate of working age population to 99 per 100 000; Decrease of mortality within one year from the first time of cancer diagnosis to 27%. …”
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  8. 4528

    How do serum cytokine levels change in myocarditis and inflammatory dilated cardiomyopathy relative to healthy individuals? A protocol for a systematic review and meta-analysis by Romuald Wojnicz, Piotr Lewandowski, Maciej Baron, Marcin A Rojek, Marcin Goławski, Karol Krystek, Magdalena Żegleń, Pascal Zytkiewicz, Jakub Kancerek, Klaudia Gabriela Lis, Jakub Warecki, Jakub Kufel, Kamila Kuśpiel

    Published 2025-02-01
    “…Accordingly, this protocol aims to conduct a systematic review and meta-analysis summarising previous research on serum and plasma levels of cytokines in patients with myocarditis and inflammatory dilated cardiomyopathy.Methods and analysis Four scientific databases: PubMed, Embase, Scopus and Web of Science, will be searched. The estimated date of the search will be 30 March 2024. Each stage of the review, including the study selection, data extraction, risk of bias and quality of evidence assessments, will be performed in duplicate. …”
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  9. 4529

    Features of model coronaviruses distribution in feline organs and tissues in the context of COVID-19 pathogenesis study by V. N. Afonyushkin, O. E. Sysoeva, O. S. Kozlova, D. V. Shamovskaya

    Published 2023-03-01
    “…To date, the reisreason to believe that, unlike classical a cuterespiratory virusinfections caused by adenoviruses, rhinoviruses, orthomyxoviruses, COVID-19 behaves completely differently. …”
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  10. 4530

    Artificial intelligence in dentistry—A review by Hao Ding, Jiamin Wu, Wuyuan Zhao, Jukka P. Matinlinna, Jukka P. Matinlinna, Michael F. Burrow, James K. H. Tsoi

    Published 2023-02-01
    “…AI is not a new term, the concept of AI can be dated back to 1950. However, it did not become a practical tool until two decades ago. …”
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  11. 4531
  12. 4532

    Migration strategy and constraint in migration behavior vary among shorebird species with different life histories by Sarah J. Clements, Jason P. Loghry, Jennifer A. Linscott, Jorge Ruiz, Joe C. Gunn, Juan G. Navedo, Nathan R. Senner, Bart M. Ballard, Mitch D. Weegman

    Published 2025-01-01
    “…There were significant differences among species in migration distance, number of stopovers used, proportion of time stopped over, departure and arrival dates, and migration duration, but not mean stopover duration. …”
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  13. 4533

    Tumor organoids in cancer medicine: from model systems to natural compound screening by Rong Cong, Can Lu, Xinying Li, Zhijie Xu, Yaqin Wang, Shusen Sun

    Published 2025-12-01
    “…Publications were selected without date restrictions, using terms such as ‘organoid’, ‘natural product’, ‘pharmacological’, ‘extract’, ‘nanomaterial’ and ‘traditional uses’. …”
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  14. 4534

    Pooled screening for CAR function identifies novel IL-13Rα2-targeted CARs for treatment of glioblastoma by Douglas A Lauffenburger, Khloe S Gordon, Caleb R Perez, Andrea Garmilla, Maxine S Y Lam, Joey J Y Aw, Anisha Datta, Andrea Pavesi, Michael E Birnbaum

    Published 2025-02-01
    “…It also showed significantly improved persistence and comparable tumor control in a microphysiological human in vitro model and a xenograft model of human glioblastoma, but also demonstrated increased off-target recognition of IL-13Rα1.Conclusion Taken together, this work demonstrates the utility of extending CARPOOL to diseases beyond hematological malignancies and represents the largest exploration of signaling combinations in human primary cells to date.…”
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  15. 4535

    Comparative evaluation of four exome enrichment solutions in 2024: Agilent, Roche, Vazyme and Nanodigmbio by Vera Belova, Iuliia Vasiliadis, Zhanna Repinskaia, Alina Samitova, Anna Shmitko, Natalya Ponikarovskaya, Oleg Suchalko, Valery Cheranev, Shatalov Peter, Shegai Peter, Kaprin Andrey, Denis Rebrikov, Dmitriy Korostin

    Published 2025-01-01
    “…This study compares available to date four exome enrichment kits: Agilent SureSelect Human All Exon v8, Roche KAPA HyperExome, Vazyme VAHTS Target Capture Core Exome Panel, and Nanodigmbio NEXome Plus Panel v1. …”
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  16. 4536

    A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities by Roggers Gang, Denis Okello, Yeongjun Ban, Youngmin Kang

    Published 2025-02-01
    “…Relevant research findings were retrieved and organized from various databases, including PubMed and ScienceDirect, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. To date, 149 phytochemicals have been identified from various A. africana parts and they primarily belong to the classes of terpenoids, lipids, hydrocarbons, phenolics, and esters. …”
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  17. 4537

    How Significant Are Marine Invertebrate Collagens? Exploring Trends in Research and Innovation by Mariana Almeida, Tiago Silva, Runar Gjerp Solstad, Ana I. Lillebø, Ricardo Calado, Helena Vieira

    Published 2024-12-01
    “…The findings reveal that research dates back to the 1970s, and after a period of reduced activity, interest in collagens from several marine invertebrate groups was renewed around 2008, likely driven by the increased commercial interest in these biomolecules of marine origin. …”
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  18. 4538

    Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma by Luigia Cinque, Flavia Pugliese, Celeste Clemente, Stefano Castellana, Maria Pia Leone, Danilo de Martino, Teresa Balsamo, Claudia Battista, Tommaso Biagini, Paolo Graziano, Marco Castori, Alfredo Scillitani, Vito Guarnieri

    Published 2020-01-01
    “…Atypical parathyroid adenoma is a rare neoplasm, showing atypical histological features intermediate between classic benign adenoma and the rarest parathyroid carcinoma, whose the clinical behaviour and outcome is not yet understood or predictable. Up to date only two cases of atypical adenoma were found associated to a MEN1 syndrome, and only one was proved to carry a pathogenic variant of the MEN1 gene. …”
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  19. 4539

    Analytical methods for nanomaterials investigation in food and food-related materials by Daniele Passeri, Pierfrancesco Atanasio, Anacleto Proietti, Chiara Mancini, Flavio Cognigni, Giancarlo La Penna, Luca Buccini, Marco Rossi, Anna Chiara Turco, Marilena D'Amato, Angela Sorbo, Simone Dinarelli, Giulia D'Ettorre, Federica Aureli

    Published 2025-06-01
    “…Here we review the main high-resolution techniques that are currently used for these characterizations in combination with the most up-to-date analytical methods, i.e., X-ray (X-ray microscopy and X-ray diffraction), scanning microscopies (electron microscopy and atomic force microscopy), optical spectroscopies (infrared spectroscopy and Raman spectroscopy), and mass spectrometry, discussing their benefits and drawbacks. …”
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  20. 4540

    Pigmented pathological type and depth of follicular extension as predictors of treatment failure in 5-aminolevulinic acid photodynamic therapy for actinic keratosis: A retrospectiv... by Qinyuan Zhu, Huyan Chen, Jing Luan, Qiong Huang, Lianjun Chen, Wenyu Wu, Shujun Chen

    Published 2025-04-01
    “…Case patients were those with treatment-resistant or recurrent AK, matched with controls based on age, sex, and the treatment date. Baseline characteristics were collected and compared between the case and control groups. …”
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