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3981
Apelin Protects Primary Rat Retinal Pericytes from Chemical Hypoxia-Induced Apoptosis
Published 2015-01-01“…Apelin, as the endogenous ligand of G protein-coupled receptor APJ, participates in a number of physiological and pathological processes. To date, the effect of apelin on pericyte is not clear. …”
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3982
Effect of Folic Acid Supplementation in Pregnancy on Preeclampsia: The Folic Acid Clinical Trial Study
Published 2013-01-01“…A web-based randomization system and electronic data collection system provide the platform for participating centers to randomize their eligible participants and enter data in real time. To date we have twenty participating Canadian centers, of which eighteen are actively recruiting, and seven participating Australian centers, of which two are actively recruiting. …”
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3983
Acute respiratory tract infections during the first 6 years of life – results from the German birth cohort study LoewenKIDS
Published 2025-04-01“…However, they impose a high socioeconomic burden and can be associated with chronic diseases later in life. To date, data on self-reported ARIs beyond infancy are limited. …”
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3984
Cost-effective whole-cell biosynthesis of ursodeoxycholic acid using engineered Escherichia coli with a multienzyme cascade
Published 2025-01-01“…This study systematically optimized the reaction parameters, including temperature, pH, and the addition of organic solvents and surfactants, for the whole-cell catalytic synthesis of UDCA by UCA23, and at the 2 L level, a UDCA conversion rate of 99% was achieved with 100 mM CDCA in 2 h, which is the highest level of conversion of a high-concentration CDCA substrate reported to date.…”
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3985
Bile Imprint on Parietal Peritoneum of Gilthead Seabream and Red Seabream: Effects of Fasting Duration, Stress, and Ice Storage
Published 2025-01-01“…The Mediterranean aquaculture industry has recently been confronted with the appearance of a bile imprint on fish filets, which to-date remains of unknown etiology. This study investigates the involvement of common procedures applied before (fasting), during (confinement), and after (ice storage) fish harvesting. …”
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3986
Swarm Confrontation Algorithm for UGV Swarm with Quantity Advantage by a Novel MSRM-MAPOCA Training Method
Published 2025-01-01“…Based on the Unity 3D platform, comprehensive direct and indirect comparative tests have been conducted, where the results show that the swarm confrontation algorithm proposed in this article triumphs over other classic or up-to-date swarm confrontation algorithms in terms of both win rate and efficiency.…”
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3987
IgG4-Related Sclerosing Disease Causing Spinal Cord Compression: The First Reported Case in Literature
Published 2019-01-01“…Hereby, we also demonstrate the dramatic response of IgG4-RD to the administration of systemic steroids as the patient had no recurrence after 5 years of close follow-up, the longest reported period of follow-up reported in the literature to date.…”
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3988
Iatrogenic Obturator Hip Dislocation with Intrapelvic Migration
Published 2018-01-01“…These types of dislocations have only been reported three other times in the literature, all within native hips. To date, there have been no reports of foraminal obturator dislocations after total hip arthroplasty. …”
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3989
Akkermansia muciniphila-directed polyphenol chlorogenic acid intervention for obesity in mice
Published 2024-01-01“…Akkermansia muciniphila play an important in ameliorating obesity but is not allowed for direct consumption in most countries. To date, microbiota-directed foods selectively promote the targeted human gut microbes, providing a strategy for A. muciniphila enhancement. …”
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3990
The Calcium Sensor CBL-CIPK Is Involved in Plant’s Response to Abiotic Stresses
Published 2015-01-01“…Diverse studies are already underway to delineate this signalling mechanism underlying different interactions. Therefore, up to date experimental results should be concisely published, thus paving the way for further research. …”
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3991
Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues
Published 2021-01-01“…The purpose of the study is aimed at being a narrative on the history of stem cells and the evolution of their use to date, as well as to clarify the bioethical position of the various religions today in comparison with the social ones regarding the research and use of embryonic and adult ones. …”
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3992
Adrenal Insufficiency in Cystic Fibrosis: A Rare Phenomenon?
Published 2018-01-01“…This study is the first to systematically examine the presence of AI in the largest cohort of CF patients studied to date with a prevalence of 8%. Patients treated with corticosteroids and those colonized with Aspergillus have a greater risk of AI.…”
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3993
Improved Outcomes with Intensity Modulated Radiation Therapy Combined with Temozolomide for Newly Diagnosed Glioblastoma Multiforme
Published 2014-01-01“…In our group, median survival for those receiving 60 Gy with Temozolomide compared favourably to the combined therapy arm of the largest randomised trial of chemoradiation versus radiation to date (17.4 months versus 14.6 months). We propose that IMRT should be considered as an alternative to 3DCRT for patients with GBM.…”
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3994
Giant Photoluminescence Enhancement of Ga‐Doped ZnO Microwires by X‐Ray Irradiation
Published 2025-01-01“…Under moderate doses (≤ 150 Gy), the photoluminescence monotonically rockets up with X‐ray dose increment and achieves nine‐fold enhancement at a dose of ≈150 Gy, recording high photoluminescence improvement of ZnO microwires to date. The elemental characteristics under different controlled irradiation atmospheres suggest the elimination of surface oxygen vacancy and the cross‐section transmission electron microscope reveals prominent lattice relaxations after mild X‐ray irradiation. …”
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3995
Application of reproductive technologies to the improvement of dairy cattle genomic selection
Published 2015-07-01“…Genomic selection can be even more profitable in combination with up-to-date reproductive biotechnologies: semen sexing, multiple ovulation and embryo transfer, ovum pick-up followed by in vitro fertilization, embryo genotyping, cloning of best breeders, etc. …”
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3996
INVESTIGATION OF RATIONAL BUBBLES AND VOLATILITY SPILLOVERS IN COMMODITY MARKETS: EVIDENCES FROM PRECIOUS METALS
Published 2019-12-01“…Due to the close formation dates ofthese bubbles, whether there was any return or volatility spillover betweengold, silver and platinum markets was investigated with VAR-EGARCH method. …”
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3997
Phylogeography of the woolly mammoth (<i>Mammuthus primigenius</i>) in the Minusinsk Depression of southern Siberia in the Late Pleistocene
Published 2024-09-01“…To date, a number of studies have been published on the phylogenetics of woolly mammoths (Mammuthus primigenius), ranging from analyses of parts of the mitochondrial genome to studies of complete nuclear genomes. …”
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3998
Role of microRNA in the risk stratification of ischemic strokes
Published 2025-02-01“…Selection criteria included human research, a certain date, or categories of studies. Data extraction, synthesis, and analysis were carried out to find trends, similarities, and differences among the chosen studies. …”
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3999
Advances in Henry Gas Solubility Optimization: A Physics-Inspired Metaheuristic Algorithm With Its Variants and Applications
Published 2024-01-01“…This study provides an up-to-date survey of HGSO, covering the walk through the historical development of HGSO, its modifications, and hybridizations with other algorithms, showcasing its adaptability and potential for synergy. …”
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4000
Scoliosis Surgery in Cystic Fibrosis: Surgical Considerations and the Multidisciplinary Approach of a Rare Case
Published 2016-01-01“…This paper reviews all the literature up to date with regard to scoliosis in patients with CF and reports this unique case of a 14-year-old Caucasian girl with progressive scoliosis, who was treated surgically at the age of 17. …”
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