HnRNPM modulates alternative splicing in germ cells by recruiting PTBP1 by Peng Lv, Wenchao Xu, Sheng Xin, Yuanxuan Deng, Bin Yang, Dengjianyi Xu, Jian Bai, Deilin Ma, Tao Wang, Jihong Liu, Xiaming Liu

“…Methods The expression of hnRNPM in germ cells at different stages was detected by polymerase chain reaction, western blotting, a single-cell database, and chromosome spreading assays. Conditional hnRNPM knockout mice were generated to observe the development of testes and germ cells in male mice. …”
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The Effect of Adjuvant Radiotherapy on One- and Two-Stage Prosthetic Breast Reconstruction and on Autologous Reconstruction: A Multicenter Italian Study among 18 Senonetwork Breast... by Andrea Vittorio Emanuele Lisa, Marzia Salgarello, Alessandra Huscher, Fabio Corsi, Daniele Piovani, Federica Rubbino, Stefania Andreoletti, Giovanni Papa, Francesco Klinger, Corrado Tinterri, Alberto Testori, Marta Scorsetti, Paolo Veronesi, Maria Cristina Leonardi, Mario Rietjens, Umberto Cortinovis, Valeria Summo, Emanuele Rampino Cordaro, Pier Camillo Parodi, Paolo Persichetti, Mauro Barone, Giorgio De Santis, Matteo Murolo, Michele Riccio, Angelica Aquinati, Francesco Cavaliere, Nicola Vaia, Giulia Pagura, Erica Dalla Venezia, Franco Bassetto, Vincenzo Vindigni, Luigi Ciuffreda, Maria Alessandra Bocchiotti, Alberto Sciarillo, Nadia Renzi, Graziano Meneghini, Tajna Kraljic, Andrea Loreti, Lucio Fortunato, Valentina Pino, Valeriano Vinci, Marco Klinger

“…Data were collected from 18 Italian Breast Centres and stored in a cumulative database which included the following: autologous reconstruction, direct-to-implant (DTI), and tissue expander/immediate (TE/I). …”
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Metabolic Profiling by UPLC–Orbitrap–MS/MS of Liver from C57BL/6 Mice with DSS-Induced Inflammatory Bowel Disease by Zhongquan Xin, Zhenya Zhai, Hongrong Long, Fan Zhang, Xiaojun Ni, Jinping Deng, Lunzhao Yi, Baichuan Deng

“…Notably, 133 metabolites were identified by an integrated database. Metabolism network and pathway analyses demonstrated that the metabolic disturbance of the liver in IBD mice was mainly enriched in bile acid metabolism, arachidonic acid metabolism, amino acid metabolism, and steroid hormone biosynthesis, while those disturbances were regulated or reversed through cecropin A and antibiotic treatment. …”
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The Beneficial Application of Turmeric (Curcuma longa L.) on Health and Egg Production, in Layers: A Review by Saade Abdalkareem Jasim, Aiman Mohammed Baqir Al‐Dhalimy, Maryam Zokaei, Shadi Salimi, Mohammed Jawad Alnajar, Abhinav Kumar, Enas R. Alwaily, Ahmed Hussein Zwamel, Soura Alaa Hussein, Majid Gholami‐Ahangaran

“…Methods A systematic search was conducted in Google Scholar database to identify relevant studies published in peer‐reviewed journals. …”
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From bench to bedside: elucidating VEGF(R) inhibitor-related heart failure in cancer treatment by Shengkun Peng, MinHong Cai, Hongyu Kuang, Anqi Lin, Qinghua Ma, Xiaoqin Dai, Peng Luo, Yijun Liu, Guo Zhang, Yifeng Bai

“…Methods We investigated the epidemiological characteristics of VEGF or VEGFR inhibitors [VEGF(R)i]-related heart failure (VirHF) using the global pharmacovigilance database Vigibase. The phenotypic features and molecular mechanisms of VirHF were characterized using VEGF(R)i-treated mouse models through a combination of echocardiography, histopathological analysis, and transcriptome sequencing. …”
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Association between vitamin D deficiency and major depression in patients with chronic kidney disease: a cohort study by I-Wen Chen, I-Wen Chen, Wei-Ting Wang, Yi-Chen Lai, Yi-Chen Lai, Ying-Jen Chang, Yao-Tsung Lin, Kuo-Chuan Hung, Kuo-Chuan Hung

“…However, the relationship between VDD and the risk of depression in this population remains unclear.MethodsUsing the TriNetX network database (2010–2019), we conducted a propensity score-matched cohort study of CKD patients aged ≥50 years. …”
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Candidate SNP markers of changes in the expression levels of the human <i>SCN9A</i> gene as a hub gene for pain generation, perception, response and anesthesia by P. A. Dotsenko, K. A. Zolotareva, R. A. Ivanov, I. V. Chadaeva, N. L. Podkolodnyy, V. A. Ivanisenko, P. S. Demenkov, S. A. Lashin, M. P. Ponomarenko

“…In this work, we for the first time performed a comprehensive bioinformatics analysis of 568 human genes that, according to the NCBI Gene database as on September 15, 2024, were associated with pain generation, perception and anesthesia. …”
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Post‐Glacial Vegetation Trajectories on the Eastern Tibetan Plateau Reflect Millennial‐Scale Migration Lags in Complex Mountain Terrain Based on Sedimentary Ancient DNA and Dynamic... by Wei Shen, Stefan Kruse, Sisi Liu, Kathleen Stoof‐Leichsenring, Ingolf Kühn, Wenjia Li, Xianyong Cao, Zhi‐Rong Zhang, Chun‐Xia Zeng, Jun‐Bo Yang, De‐Zhu Li, Ulrike Herzschuh

“…We applied plant DNA metabarcoding to lake sediments leveraging a new regional reference database for taxa identification. Furthermore, we developed a simplified species dispersal model named SMARC. …”
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Preoperative Education is Associated with Adherence to Downstream Components and Outcomes in a Colorectal Surgery Enhanced Recovery Program by Bayley A. Jones, MD, Joshua Richman, MD, PhD, Michael Rubyan, PhD, MPH, Lauren Wood, MSPH, Alfonsus Adrian H. Harsono, MD, MSPH, Wendelyn Oslock, MD, MBA, Nathan English, MBChB, Burkely P. Smith, MD, Robert Hollis, MD, MSPH, Larry R. Hearld, PhD, Isabel Scarinci, PhD, MPH, Daniel I. Chu, MD, MSPH

“…Our institutional ERP database was linked with American College of Surgeons National Surgical Quality Improvement Program data and stratified by adherence to preoperative education. …”
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Transcriptional landscape and predictive potential of long noncoding RNAs in peritoneal recurrence of gastric cancer by Xiao-Xia Cai, Guo-Ming Chen, Zi-Qi Zheng, Yi-Xin Yin, Shuang Wang, Li Qiao, Xiao-Jiang Chen, Bai-Wei Zhao, Jin-Ling Duan, Cheng-Cai Liang, Ruo-Peng Zhang, Cheng-Zhi Wei, Fei-Yang Zhang, Bo-Wen Huang, Ze-Xian Liu, Zhi-Wei Zhou, Dan Xie, Mu-Yan Cai, Shu-Qiang Yuan, Yuan-Fang Li, Run-Cong Nie

“…Key lncRNAs were identified via interactive analysis with the TCGA database and SYSUCC validation cohort. A score model was constructed using the LASSO regression model and nomogram COX regression and evaluated using receiver operating characteristic curves. …”
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Emergency department laparotomy for patients with severe abdominal trauma: a retrospective study at a single regional trauma center in Korea by Yu Jin Lee, Soon Tak Jeong, Joongsuck Kim, Kwanghee Yeo, Ohsang Kwon, Kyounghwan Kim, Sung Jin Park, Jihun Gwak, Wu Seong Kang

“…Methods We reviewed the data recorded in our center’s trauma database between January 2020 and December 2022 and identified patients who underwent laparotomy because of abdominal trauma. …”
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Prognostic significance of albumin corrected anion gap in patients with acute pancreatitis: a novel perspective by Jianjun Wang, Pei Yang, Xintao Zeng, Sirui Chen, Xi Chen, Lan Deng, Ruizi Shi, Chuan Qin, Huiwen Luo, Jianping Gong, Hua Luo, Decai Wang

“…We conducted a retrospective analysis utilizing data extracted from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. This study sought to investigate the correlation between ACAG and ACM among patients diagnosed with AP across various disease stages. …”
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Impact of infection in patients with non-ST elevation acute coronary syndrome undergoing percutaneous coronary intervention: insight from a multicentre observational cohort from Ch... by Jun Li, Lei Jiang, Wei Chen, Ning Tan, Wei Guo, Ji-yan Chen, Yuan-hui Liu, Peng-cheng He, Peng-Yuan Chen, Chong-Yang Duan, Xue-Biao Wei, Yin-Lin Zhou, Zhu-Jun Chen, Jian-Fang Luo, Dan-Qing Yu, Qing-Shan Geng, Chun-Ying Lin, Zhi-Qiang Guo, Yan-Song Guo, Yi-Yue Chen, Wen-Sheng Li

“…Objective We aimed to describe the association between in-hospital infection and prognosis among patients with non-ST elevation acute coronary syndrome (NSTE-ACS) who received percutaneous coronary intervention (PCI).Design This observational cohort originated from a database of patients with NSTE-ACS who underwent PCI from 1 January 2010 to 31 December 2014.Setting Five centres in South China.Participants This multicentre observational cohort study consecutively included 8197 patients with NSTE-ACS who received PCI. …”
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Income Dynamics and Risk of Colorectal Cancer in Individuals With Type 2 Diabetes: A Nationwide Population-based Cohort Study by Yong-Moon Mark Park, Benjamin C. Amick III, Pearl A. McElfish, Clare C. Brown, Mario Schootman, Marie-Rachelle Narcisse, Seong-Su Lee, Yoon Jin Choi, Kyungdo Han

“…Methods: Using nationally representative data from the Korean Health Insurance Service database, 1,909,492 adults aged 30 to 64 years with T2DM and no history of cancer were included between 2009 and 2012 (median follow-up of 7.8 years). …”
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Risk Factors of Bacteremia following Multiple Traumas by Hak-Jae Lee, Eol Choi, Nak-Joon Choi, Hyun-Woo Sun, Jae-Suk Lee, Jeong-Woo Lee, Tae-Yoon Kim, Yoon-Joong Jung, Suk-Kyung Hong

“…The information was collected for each patient and recorded in a computer database: early onset bacteremia (EOB) was defined as when onset occurred within 7 days after trauma, and late onset bacteremia (LOB) was defined as when onset occurred after 7 days from trauma. …”
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Utilizing TP53 hotspot mutations as effective predictors of gemcitabine treatment outcome in non-small-cell lung cancer by Yen-Han Tseng, Trieu Thi My Tran, Jinghua Tsai Chang, Yu-Tang Huang, Anh Thuc Nguyen, Ian Yi‑Feng Chang, Yi-Tung Chen, Hao-Wen Hsieh, Yue-Li Juang, Peter Mu-Hsin Chang, Tzu-Yi Huang, Ying-Chih Chang, Yuh-Min Chen, Hsuan Liu, Chi-Ying F. Huang

“…Potential drugs were identified by comparing drug sensitivity differences, represented by the half-maximal inhibitory concentration (IC50), between TP53 mutant and wild-type NSCLC cell lines using database analysis. In addition, clinical data from NSCLC patients were collected to evaluate both their TP53 status and their response to gemcitabine, thereby facilitating further validation. …”
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Dietary fiber consumption and outcomes of different cancers: an umbrella review by Xingyu He, Jiayi Hou, Lei Liu, Xin Chen, Lijie Zhang, Caojia Pang, Yu Tong, Hongling Li, Feng Chen, Rong Peng, Zheng Shi

“…Methods: An umbrella review was conducted, analyzing existing systematic reviews and meta-analyses from PubMed, Embase, and the Cochrane Database of Systematic Reviews. This included data from 26 meta-analyses based on 2,107 unique articles, covering 52 observational study outcomes. …”
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Global temporal trends and projections of hepatitis B-related cirrhosis among adolescents and young adults from 1990 to 2035: an analysis based on the global burden of disease stud... by Quanwei He, Quanwei He, Quanwei He, Xiujuan Chang, Ran Xu, Ran Xu, Wei Han, Wei Han, Sihao Wang, Sihao Wang, Shujuan Gong, Shujuan Gong, Jiagan Huang, Jiangtao Liu, Rugang Zhang, Yongping Yang, Yongping Yang, Yongping Yang

“…This study aimed to assess the disease burden and trends.MethodsPublicly available data were obtained from the 2021 GBD database. The rates of incidence, mortality, and disability-adjusted life years were calculated at the global, regional, and national levels. …”
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Chest wall injury fracture patterns are associated with different mechanisms of injury: a retrospective review study in the United States by Jennifer M. Brewer, Owen P. Karsmarski, Jeremy Fridling, T. Russell Hill, Chasen J. Greig, Sarah E. Posillico, Carol McGuiness, Erin McLaughlin, Stephanie C. Montgomery, Manuel Moutinho, Ronald Gross, Evert A. Eriksson, Andrew R. Doben

“…The Chest Injury International Database (CIID) is the largest prospective repository of the operative and nonoperative management of patients with severe chest wall trauma. …”
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Analysis of Soil Microbial Community Structure and Function in <i>Morchella esculenta</i> Habitats in Jilin Province by Qi Yan, Peng Wang, Zhushan Liu, Ya Yu, Xiao Tan, Xiao Huang, Jiawei Wen, Weidong Zhang

“…The functional annotation analysis of soil microorganisms, based on the KEGG database, revealed that within level A (highest tier), metabolic activities were the most prominent. …”
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