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9761
Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses
Published 2025-01-01“…Methods RNA sequencing (RNA‐seq) datasets were retrieved from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were identified using GEO2R. …”
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9762
Predictive value of TG/HDL-C and GFR-adjusted uric acid levels on cardiovascular mortality: the URRAH study
Published 2025-01-01“…Methods Data from 18,694 subjects were analyzed from Uric acid Right foR heArt Healt (URRAH) database. The study evaluated the association between TG/HDL-C ratio and SUA/GFR ratio, as well as their impact on the development of outcomes during the follow-up study period. …”
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9763
CO2 levels and SARS-CoV-2 transmission in public schools: A retrospective cohort study in Montreal (Canada)
Published 2025-03-01“…During this pandemic period, the Montreal Public Health Department investigated COVID-19 cases among students and staff in public elementary and high schools, gradually developing a regional database of school cases and outbreaks from intervention files. …”
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9764
May Measurement Month 2020: An Analysis of Blood Pressure Screening Results From China
Published 2025-01-01“…Blood pressure was measured three times consecutively with a 1‐min interval in the sitting position, using a validated automated BP monitor (Omron HEM‐7081IT), and transmitted to a central database via a smartphone app. The measurement was performed at 136 sites across 29 China provinces. …”
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9765
Environmental DNA metabarcoding shows potential for monitoring meiofauna and marine nematodes diversity in mangrove ecosystems in China
Published 2025-01-01“…The appropriate specific primers, a comprehensive database, and the definitive correlation between individual counts and sequences are crucial for the further widespread implementation of eDNA metabarcoding in monitoring meiofauna and marine nematodes diversity.…”
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9766
Relationship between kidney function and healthy life expectancy: A historical cohort study
Published 2025-01-01“…Methods This study of community-dwelling adults residing in Hakui City, Ishikawa Prefecture, Japan used data from the National Health Insurance database between 2012 and 2022. Participants were grouped by baseline estimated glomerular filtration rate (eGFR) (< 45, ≥ 45 to < 60, ≥60 to < 75, ≥75 to < 90, and ≥ 90 mL/min/1.73 m²). …”
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9767
Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK
Published 2015-12-01“…We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.Design Retrospective cohort study from 2000 to 2012.Setting 627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.Participants Each identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.Outcome measures Prevalence rates were calculated for 16 conditions.Results SMI rates were highest in Scotland and in more deprived areas. …”
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9768
Prognostic Factors for Clinical Response in Systemic Lupus Erythematosus Patients Treated by Allogeneic Mesenchymal Stem Cells
Published 2019-01-01“…All adult patients identified in the Nanjing database with an SLE Disease Activity Index (SLEDAI) score≥8 at baseline that had undergone MSC transplant and who had at least 1 year of follow-up after one or two successive intravenous injections of allogeneic BM-/UC-MSCs (1 million/kg) were analyzed. …”
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9769
Relationships between environmental variables and free-living nematode communities in seasonally flooded wetlands
Published 2020-10-01“…This study aims to provide a new database of the nematode’s structure in the seasonally flooded wetland and its relation with environmental variables as well as detection of the ecological quality, considering nematodes as bioindicators. …”
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9770
Incidence and temporal trends of out-of-hospital cardiac arrest in Shenzhen, China (2011–2018)
Published 2025-03-01“…Methods: This retrospective study analysed data from the Shenzhen Emergency Center database (2011–2018), including ambulance dispatch and pre-hospital medical records. …”
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9771
Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage
Published 2025-02-01“…We compared the differences between spasm and non-spasm groups after cerebral hemorrhage, identifying 183 differentially expressed genes (DEGs) and 19 differentially expressed miRNAs (DEMs) related to cerebral vasospasm from the GEO database. Further functional enrichment and KEGG analysis revealed that these DEGs were enriched in several terms and pathways, including the PI3K/AKT/mTOR signaling pathway, oxidative phosphorylation pathway, RNA degradation, and folate biosynthesis signaling pathway. …”
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9772
Impact of same-day ART initiation on medical care and medication discontinuation among patients with incident HIV infection or AIDS in Taiwan: A population-based cohort study
Published 2025-04-01“…Data were collected from the National Health Insurance claims database. We defined care discontinuation as having no clinical visits for over 90 days since the last clinical visit and medication discontinuation as failing to pick up medication 30 days after the expected medication pick-up date. …”
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9773
The features of Tat protein of human immunodeficiency virus type 1 (Retroviridae: <i>Lentivirus: Lentivirus humimdef1</i>) non-A6 variants, characteristic for the Russian Federatio...
Published 2024-12-01“…Preferentially, the sequences were downloaded from the international database Los Alamos. Results. CRF63_02A6 consensus sequence contained the highest number of amino acid substitutions, 31, and had no helix at positions 30‒33 in the secondary structure; however, this did not change its predicted tertiary structure. …”
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9774
Assessment of prognosis and responsiveness to immunotherapy in colorectal cancer patients based on the level of immune cell infiltration
Published 2025-02-01“…ObjectiveTo build a new prognostic risk assessment model based on immune cell co-expression networks for predicting overall survival and evaluating the efficacy of immunotherapy for colon cancer patients.MethodsThe Cancer Genome Atlas (TCGA) database was used to obtain mRNA expression profiling data, clinical information, and somatic mutation data from colorectal cancer patients. …”
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9775
Association of Cardiovascular Autonomic Neuropathy and Distal Symmetric Polyneuropathy with All-Cause Mortality: A Retrospective Cohort Study
Published 2021-01-01“…All diabetes cases (n=1,347) from the catchment area of a secondary diabetes care centre who had medical examination including neuropathy assessment between 1997 and 2016 were followed up for all-cause mortality in the NHS Hungary reimbursement database until 2018. We investigated the association of CAN (Ewing tests) and DSPN (Neurometer) with all-cause mortality using Cox models stratified by diabetes type. …”
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9776
Bidirectional relationship between depression and activities of daily living and longitudinal mediation of cognitive function in patients with Parkinson’s disease
Published 2025-02-01“…ObjectiveTo investigate the bidirectional relationship between depression and activities of daily living (ADL) in Parkinson’s disease (PD) patients and explore the mediating role of cognitive function over time.MethodsData from 892 PD patients from the Parkinson’s Progression Markers Initiative (PPMI) database were included in this study, and depression, cognitive function, and ADL were measured using the Geriatric Depression Scale (GDS-15), Montreal Cognitive Assessment Scale (MoCA), and Unified Parkinson’s Disease Rating Scale, Part II (UPDRS II) respectively. …”
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9777
Impacts of intestinal microbiota metabolite trimethylamine N-oxide on cardiovascular disease: a bibliometric analysis
Published 2025-01-01“…BackgroundTrimethylamine N-oxide (TMAO), a metabolite dependent on intestinal microbiota, is closely related to the emergence, progression, and prognosis of cardiovascular disease (CVD), and has received increasing attention in recent years.ObjectiveThe current research hotspots and future development trends in TMAO and CVD field are found through bibliometrics analysis, which provides reference for further study.MethodsThe bibliometrics tools VOSviewer and CiteSpace were used to analyze the publications from the Web of Science Core Collection (WOSCC) database. The articles published from 2004 to 2024 about the relationship between TMAO and CVD were retrieved. …”
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9778
Personalized screening strategies for TP53 R337H carriers: a retrospective cohort study of tumor spectrum in Li-Fraumeni syndrome adult carriersResearch in context
Published 2025-02-01“…Methods: We retrospectively analyzed 708 adults, combining data from two sources: the Brazilian Li-Fraumeni Syndrome Study cohort and the NCI TP53 database. We assessed the clinical characteristics of 303 adults with R337H and compared them with those associated with 405 carriers of other TP53 variants. …”
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9779
Evaluation of variation in special educational needs provision and its impact on health and education using administrative records for England: umbrella protocol for a mixed-method...
Published 2023-11-01“…Triangulation of findings on outcomes, variation and impact of SEN provision for different health phenotypes in ECHILD, with experiences of SEN provision will inform interpretation of findings for policy, practice and families and methods for future evaluation.Ethics and dissemination Research ethics committees have approved the use of the ECHILD database and, separately, the survey, interviews and focus groups of young people, parents and service providers. …”
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9780
Comparison of the lethal triad and the lethal diamond in severe trauma patients: a multicenter cohort
Published 2025-01-01“…Methods We performed a multicenter retrospective analysis of patients in TraumaBase®, a French database (2011–2023). The patients included in this study were all trauma patients who had received transfusions of at least 1 unit of red blood cells (RBCs) within the first 6 h of hospital admission and for whom ionized calcium measurements were available. …”
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