Geography and age drive racial and ethnic disparities in hospital mortality for paediatric community-acquired pneumonia in the United States: a retrospective population based cohor... by Cody-Aaron L. Gathers, Nadir Yehya, Anireddy Reddy, Paula M. Magee, Vanessa C. Denny, Michelle R. Mayeda, Amanda O’Halloran, Sanjiv D. Mehta, Stephanie Wanamaker, Jessica C. Fowler, Garrett Keim

“…Methods: This was a retrospective cohort study of children age < 18 years with community-acquired pneumonia hospitalized between 2016 and 2021 in the Public Health Information System (PHIS) database. Models included a priori stratification of age ≤ 1 year and geographic region. …”
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Regulatory role of lnc-MAP3K13-3:1 on miR-6894-3p and SHROOM2 in modulating cellular dynamics in hepatocellular carcinoma by Kuai Chen, Manqin Zhu, Qinghua Hu, Hui Huang, Ka Chen, Xia Shuai, Jinshi Huang, Qiang Tao, Zhibin Guo

“…Consequently, identifying molecular targets that specifically inhibit the proliferation and metastasis of HCC cells is critical for improving treatment outcomes. Database analysis using Targetscan identified complementary binding sites for the human-specific miRNA hsa-miR-6894-3p (hereafter referred to as miR-6894-3p) on SHROOM2, and Starbase data suggested a potential regulatory interaction between lnc-MAP3K13-3:1 and miR-6894-3p in liver cancer. …”
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Risk Factors of Portal Vein Thrombosis in Patients with Different Child-Pugh Classes Liver Cirrhosis by M. Yu. Nadinskaia, Kh. B. Kodzoeva, K. A. Gulyaeva, M.-D. E. Khen, D. I. Koroleva, M. A. Privalov, A. Kh. Tekaeva, V. R. Fedorov, S. G. Prokofev

“…The Case group included 130 patients with newly diagnosed PVT not caused by invasive hepatocellular carcinoma (HCC); 29 patients were assigned to class A, 101 patients were assigned to class B/C. From the database of cirrhotic patients without PVT 60 Controls for class A and 205 for B/C were selected using sratified randomization by sex, age and etiology of cirrhosis. …”
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Characteristics of Traditional Human Settlement Landscapes on Bedrock Islands in Guangdong Based on the “Ao” Unit by Ying PAN, Linxi CHEN, Ying SHI

“…Through this approach, a robust database of the Ao units on Nan’ao Island is meticulously compiled, encompassing information such as location, area, industry type, historical background, cultural beliefs, and origins of the island’s immigrants. …”
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Mixture density networks for re-constructing historical ocean-color products over inland and coastal waters: demonstration and validation by Sundarabalan V. Balasubramanian, Ryan E. O’Shea, Ryan E. O’Shea, Arun M. Saranathan, Arun M. Saranathan, Christopher C. Begeman, Christopher C. Begeman, Daniela Gurlin, Caren Binding, Claudia Giardino, Michelle C. Tomlinson, Krista Alikas, Kersti Kangro, Moritz K. Lehmann, Moritz K. Lehmann, Lisa Reed

“…Our model is validated on satellite match-ups corresponding to the SeaWiFS Bio-optical Archive and Storage System (SeaBASS) database. For both training and validation, the hyperspectral in situ radiometric and absorption datasets were resampled via the relative spectral response functions of MODIS, MERIS, and VIIRS to simulate the response of each multispectral ocean color mission. …”
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Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment by Tangyi Wang, Yadian Lei, Jingwei Sun, Li Wang, Yuxin Lin, Zhijing Wu, Shoude Zhang, Chengzhu Cao, Chengzhu Cao, Chengzhu Cao, Haiyan Wang, Haiyan Wang, Haiyan Wang

“…Bioinformatics tools, including bc-GenExMiner v4.8, the Human Protein Atlas, and the TIMER database, were utilized for target identification. …”
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Splenic artery aneurysms – a systematic review of the literature by Marta Machado, Andreia Coelho, João Peixoto, Luís Fernandes, Roberto Boal, Francisco Basílio, Patrícia Carvalho, Beatriz Guimarães, Pedro Brandão, Alexandra Canedo

“…A literature search was performed using the Medline database from January 2019 to January 2024. Only full-text articles were considered, including patients with true SAA treated by endovascular (ET) and/or open surgical (OS) means. …”
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HIF-1α and VEGF Immunophenotypes as Potential Biomarkers in the Prognosis and Evaluation of Treatment Efficacy of Atherosclerosis: A Systematic Review of the Literature by Dimitra P. Vageli, Panagiotis G. Doukas, Dimitrios Georgiou, Michailangelos P. Prokopiou, Nefeli E. Ladaki, Androniki Papadopoulou, Sotirios G. Doukas, Konstantina Zacharouli, Konstantinos P. Makaritsis, Maria Ioannou

“…We used the terms {“Atherosclerosis” [OR] “Atheroma” [OR] “atheromatous plaque” [OR] “plaque atherosclerotic”} [AND] {“HIF-1α”} [AND] {“VEGF”} from 2009 up to May 2024 and the Medline/Embase/PubMed database. We used methodological approaches to assess unbiased data [ROBIS (Risk of Bias in Systematic) tool]. …”
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Radiotherapy-induced Hypothalamic-Pituitary axis dysfunction in adult Brain, head and neck and skull base tumor patients – A systematic review and Meta-Analysis by J.M.J. Paulissen, C.M.L. Zegers, R.M. Houben, D. Hofstede, M. Kars, H.M. van Santen, F.J.P. Hoebers, D.K.M. De Ruysscher, D.B.P. Eekers

“…Materials and methods: Literature search of the PubMed database was performed for HP dysfunction after radiotherapy in adult patients. …”
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The Role of Open and Distance Learning (ODL) in Promoting Access to Women's Education in Northwestern Nigeria: A Case Study of the National Open University of Nigeria (NOUN) by Shehu Usman Adamu, Bala Kwata Waziri, Adewale Adesina, Babangida Iro

“… A survey was conducted using the National Open University database to ascertain the number of women from the northwestern states of Jigawa, Kaduna, Kano, Katsina, Kebbi, Sokoto and Zamfara studying in the University based on the admission records from 2018 to 2022. …”
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Development of the destination branding model based on tourism industry nostalgia by parinaz masoumi, vahidreza mirabi, jalal HaghighatMonfared, Ahmad Vedadi

“…Data analysis was done in qualitative method with database approach and MAXQDA 20 software. Validation of the model was done with partial least squares technique and SmartPLS software. …”
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Global, regional, and national epidemiology of childhood neuroblastoma (1990–2021): a statistical analysis of incidence, mortality, and DALYsResearch in context by Jusen Nong, Cheng Su, Changhua Li, Congjun Wang, Wei Li, Yong Li, Peng Chen, Yanqiang Li, Zihao Li, Xinjin She, Zuxin Yuan, Sentian Liu, Chao Chen, Qian Liao, Yige Luo, Bo Shi

“…Methods: The study utilized data from the Global Burden of Disease (GBD) database to analyze neuroblastoma incidence, mortality, and DALYs in children aged 0–14 years. …”
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Satellite quantification of methane emissions from South American countries: a high-resolution inversion of TROPOMI and GOSAT observations by S. E. Hancock, D. J. Jacob, Z. Chen, H. Nesser, A. Davitt, A. Davitt, D. J. Varon, M. P. Sulprizio, N. Balasus, L. A. Estrada, M. Cazorla, L. Dawidowski, S. Diez, J. D. East, E. Penn, C. A. Randles, C. A. Randles, J. Worden, I. Aben, R. J. Parker, R. J. Parker, J. D. Maasakkers

“…From the inversion, we derive optimal posterior estimates of methane emissions, adjusting a combination of national anthropogenic emission inventories reported by individual countries to the United Nations Framework Convention on Climate Change (UNFCCC), the UNFCCC-based Global Fuel Exploitation Inventory (GFEIv2), and the Emissions Database for Global Atmospheric Research (EDGARv7) as prior estimates. …”
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Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade by Shaoyong Peng, Minshan Wu, Qian Yan, Gaopo Xu, Yumo Xie, Guannan Tang, Jinxin Lin, Zixu Yuan, Xiaoxia Liang, Ze Yuan, Jingrong Weng, Liangliang Bai, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo, Xiaoxia Liu

“…Methods Flow cytometric, Western blotting, proteomics analysis, analysis of public database data, genetically modified cell line models, T cell coculture, crystal violetstaining, ELISA, metabonomic and clinical tumour samples were conducted to assess the role of EDEM3 in immune escape and itsmolecular mechanisms. …”
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Exometabolomic exploration of culturable airborne microorganisms from an urban atmosphere by R. Jin, W. Hu, W. Hu, P. Duan, M. Sheng, D. Liu, Z. Huang, M. Niu, L. Wu, J. Deng, P. Fu, P. Fu

“…Annotation through the Kyoto Encyclopedia of Genes and Genomes database helped identify metabolic processes. Results showed that bacterial and fungal strains produced exometabolites with lower H <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M1" display="inline" overflow="scroll" dspmath="mathml"><mo>/</mo></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="8pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="1b4178c77ca0d4bfee6c9ddd864f3a43"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="acp-25-1805-2025-ie00001.svg" width="8pt" height="14pt" src="acp-25-1805-2025-ie00001.png"/></svg:svg></span></span> C and higher O <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M2" display="inline" overflow="scroll" dspmath="mathml"><mo>/</mo></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="8pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="527256ea34e0af356380afd605ccefc0"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="acp-25-1805-2025-ie00002.svg" width="8pt" height="14pt" src="acp-25-1805-2025-ie00002.png"/></svg:svg></span></span> C ratios compared with both consumed and resistant compounds. …”
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Surgeons are apprehensive to use DCD lungs despite similar post-transplant outcomes: A 20-year UNOS retrospective analysis by J. Sam Meyer, MSc, Oliver K. Jawitz, MD, MHS, Yury Peysakhovich, MD, Dan Aravot, MD, Matthew G. Hartwig, MD, MHS, Yaron D. Barac, MD, PhD

“…Methods: We performed a retrospective analysis of United Network for Organs Sharing (UNOS) Organ Procurement and Transplantation Network/UNOS STAR (Standard Analysis and Research) database. Donors who donated ≥1 organ from 10/1999–01/2019 were extracted and stratified according to DBD and DCD status. …”
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Biosynthesis inhibition of miR-142-5p in a N 6-methyladenosine-dependent manner induces neuropathic pain through CDK5/TRPV1 signaling by Jinshi Li, Yang Guo, Chen Zhu, Dongxu Wang, Yuan Li, Xiaotong Hao, Linyan Cao, Yiting Fan, Bo Fang

“…Notably, CDK5 was found to directly bind to TRPV1, and the binding region was localized within the 1–390 amino acid sequence of TRPV1. According to database predictions, miR-142-5p, identified as a shared upstream molecule of TRPV1 and CDK5, exhibited downregulation following induction by NP. …”
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Research on Characteristics and Influencing Factors of High Temperature Disaster Risk in Wuhan Based on Local Climate Zone by Shujing GUO, Li ZHANG

“…Then Landsat 8 remote sensing images are processed with SAGA GIS software, Google Earth Pro software, and Random Forest algorithm to classify the urban development area of Wuhan into 17 local climate zone (LCZ) types based on the remote sensing image classification method of World Urban Database and Access Portal Tools (WUDAPT). With 70% random samples used for drawing and 30% random samples used for checking, LCZ maps that meet the requirements of classification accuracy are obtained and analyzed for site identification at the local scale. …”
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“Restoration of the Past Scenery-Realm”: A Research on the Scenery-Realm Restoration of Jiang’s Fu Garden During Qing Dynasty in the Historical Revolution of the Humble Administrat... by Qian BIAN

“…However, due to the limitations imposed by the differences in research subjects and the insufficiency of historical materials before, the key questions of what had been “fu” (restored) in this garden and what qualified the garden as a “fu” (restoration) of the past scenery-realm have not been sufficiently elucidated.MethodsThis research employs targeted searches within the Suzhou Library’s Ancient Book Database to augment the existing corpus of literature pertaining to Jiang’s Fu Garden. …”
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Construction of a prognostic model for gastric cancer based on immune infiltration and microenvironment, and exploration of MEF2C gene function by Si-yu Wang, Yu-xin Wang, Lu-shun Guan, Ao Shen, Run-jie Huang, Shu-qiang Yuan, Yu-long Xiao, Li-shuai Wang, Dan Lei, Yin Zhao, Chuan Lin, Chang-ping Wang, Zhi-ping Yuan

“…Tumor-related transcription factors (TFs) were retrieved from the Cistrome Cancer database and utilized our model to screen these TFs, and weighted correlation network analysis (WGCNA) was performed to identify transcription factors strongly associated with immunotherapy in GC. …”
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