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7621
A Novel Immune-Related lncRNA-Based Model for Survival Prediction in Clear Cell Renal Cell Carcinoma
Published 2021-01-01“…Immune-related gene sets and transcription factor genes were downloaded from GSEA website and Cistrome database, respectively. Tumor samples were divided into the training set and the testing set. …”
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7622
Implementation of prehospital point-of-care ultrasound using a novel continuous feedback approach in a UK helicopter emergency medical service
Published 2025-02-01“…Methods A retrospective database review was undertaken at London’s Air Ambulance (LAA) from 1st September 2021 to 31st March 2023. …”
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7623
Ethnoracial disparities in childhood growth trajectories in Brazil: a longitudinal nationwide study of four million children
Published 2024-02-01“…Objective We aimed to investigate child growth according to maternal ethnoracial group using a nationwide Brazilian database. Methods A population-based retrospective cohort study employed linked data from the CIDACS Birth Cohort and the Brazilian Food and Nutrition Surveillance System (SISVAN). …”
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7624
„Wykazy czasopism MNiSW 2017 i 2019”, „ICI Journal Master List 2014–2017” a polskie czasopisma z historii nauki, historii, filozofii nauki oraz naukoznawstwa
Published 2019-11-01“…The following facts were noted: a) the fact that there is a negative correlation between the journal’s rating in the “List of journals MNiSW 2019” and the journal’s ratings in the “ICI Journal Master List 2014–2017” for journals from the history and history of science; b) the fact that the presence of the journal in the DOAJ does not raise the ministerial rating of the journal; c) the fact that the evaluation of the journal in the Scopus database has not significantly affected the increase in the ministerial rating: the rating depends on the discipline and sub-discipline; d) the fact that journals from the ministerial program “Support for scientific journals 2019–2020” (WCN 2019–2020) and ERIH+ received 20 to 70 points; their ministerial ratings depend on discipline and sub-discipline. …”
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7625
Systematic review and quantitative meta-analysis of age-dependent human T-lymphocyte homeostasis
Published 2025-01-01“…Age-dependent homeostasis of each T-lymphocyte subpopulation was evaluated via a weighted average calculation within pre-specified age intervals, using a piece-wise equal-effect meta-analysis methodology.ResultsIn total, 124 studies comprising 11722 unique observations from healthy subjects encompassing 20 different T-lymphocyte subpopulations – total CD45+ and CD3+ lymphocytes, as well as specific CD4+ and CD8+ naïve, recent thymic emigrants, activated, effector and various subpopulations of memory T-lymphocytes (total-memory, central-memory, effector-memory, resident-memory) – were systematically collected and included in the final database for a comprehensive analysis. Blood counts of most T-lymphocyte subpopulations demonstrate a decline with age, with a pronounced decrease within the first 10 years of life. …”
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7626
The predictive value of the serum creatinine-to-albumin ratio (sCAR) and lactate dehydrogenase-to-albumin ratio (LAR) in sepsis-related persistent severe acute kidney injury
Published 2025-01-01“…Methods We acquired training set data from the MIMIC-IV database and validation set data from the First Affiliated Hospital of Harbin Medical University. …”
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7627
MAZ-mediated tumor progression and immune evasion in hormone receptor-positive breast cancer: Targeting tumor microenvironment and PCLAF+ subtype-specific therapy
Published 2025-02-01“…Methods: The study utilized single-cell RNA sequencing (scRNA-seq) data sourced from the Gene Expression Omnibus database and The Cancer Genome Atlas to analyze HR+BC and identify key cellular characteristics. …”
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7628
Single-Cell Transcriptome Analysis Reveals Different Immune Signatures in HPV- and HPV + Driven Human Head and Neck Squamous Cell Carcinoma
Published 2022-01-01“…Data were downloaded from GEO database (GSE139324), including 131224 cells from 18 HP- HNSCC patients and 8 HPV+ HNSCC patients. …”
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7629
Characteristics and outcomes of out-of-hospital cardiac arrest among students under school supervision in Japan: a descriptive epidemiological study (2008–2021)
Published 2025-01-01“…Methods: OHCA data from 2008–2021 were obtained from the SPIRITS study, which provides a nationwide database of OHCAs occurring under school supervision across Japan. …”
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7630
Durable responders in advanced NSCLC with elevated TMB and treated with 1L immune checkpoint inhibitor: a real-world outcomes analysis
Published 2023-01-01“…Here, we examined the complementary roles of tumor mutational burden (TMB) and programmed death ligand-1 (PD-L1) immunohistochemistry (IHC) to inform first-line therapy using a large real-world (rw) data set.Materials and methods The study included patients with NSCLC from an rw de-identified clinico-genomic database. All patients underwent genomic testing using Foundation Medicine’s tissue comprehensive genomic profiling assay and PD-L1 IHC assay scored for tumor cell staining (TS).Results Of 2165 patients included in the analysis, 150 exhibited durable benefit from first-line ICPI regimens (these patients were enriched for PD-L1 TS ≥50, non-squamous histology, and TMB ≥20 mutations/megabase (muts/Mb)). …”
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7631
Real-world short-term outcomes and treatment regimen comparisons in patients with metastatic renal cell carcinoma treated with first-line immune combinations
Published 2025-01-01“…This study evaluated the applicability of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) risk model in predicting outcomes for patients treated with either immune-oncologic drug doublet (IO-IO) or immune-oncologic drug tyrosine kinase inhibitor combinations (IO-TKI). …”
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7632
Organisational Enablers of Artificial Intelligence Adoption in Public Institutions: A Systematic Literature Review
Published 2024-05-01“…Comprehensive search queries in the Scopus database identified relevant literature focusing on the intersection of AI technologies and various organisational elements. …”
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7633
Integrating bulk and single-cell RNA sequencing data: unveiling RNA methylation and autophagy-related signatures in chronic obstructive pulmonary disease patients
Published 2025-02-01“…We analyzed tissue-based bulk RNA sequencing and single-cell RNA sequencing (scRNA-seq) datasets from COPD and non-COPD patients, sourced from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were identified between COPD and non-COPD samples, and protein–protein interaction networks were constructed. …”
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7634
Cancer mortality and sectors of employment: a cohort study in Italy
Published 2025-02-01“…Methods We used a cohort from the Rome Longitudinal Study (ROL) and linked it with the National Social Insurance Agency (INPS) database to obtain working histories. We considered the longest duration of employment in a sector as a proxy of exposure, and insurance activities as the reference category. …”
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7635
Which patients received a ReSPECT form, what was documented and what were the patient outcomes? A protocol for a retrospective observational study investigating the impact of the C...
Published 2022-07-01“…Data will be exported from the CCG Public Health Management data resource, a pseudonymised database linking data from organisations providing health and social care to people across BNSSG. …”
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7636
Evaluation and Management of Patients with Seizures in the Emergency Department: A One-Year Analysis
Published 2018-09-01“…The data was cross-sectional and was retrieved from the local database of Vilnius University Hospital Santaros Klinikos from January 1st to December 31st, 2016. …”
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7637
Upregulated SAE1 Drives Tumorigenesis and Is Associated with Poor Clinical Outcomes in Breast Cancer
Published 2024-01-01“…Bioinformatics analysis was applied to analyze SAE1 expression in BC and normal breast tissues, its relationship with clinicopathologic characteristics and prognosis in BC patients, and data from the Cancer Genome Atlas database and Gene Expression Omnibus dataset. We performed immunohistochemistry to analyze SAE1 expression in BC tissues and para-cancer tissues in 79 breast cancer patients. …”
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7638
CD200R1 immune checkpoint blockade by the first-in-human anti-CD200R1 antibody 23ME-00610: molecular mechanism and engineering of a surrogate antibody
Published 2024-12-01“…Human CD200R1 (hCD200R1), an immune inhibitory receptor expressed predominantly on T cells and myeloid cells, was identified as a promising immuno-oncology target by the 23andMe database. Blockade of CD200R1-dependent signaling enhances T cell-mediated antitumor activity in vitro and in vivo. 23ME–00610 is a potential first-in-class, humanized IgG1 investigational antibody that binds hCD200R1 with high affinity. …”
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7639
Identification of a 5-Gene-Based Scoring System by WGCNA and LASSO to Predict Prognosis for Rectal Cancer Patients
Published 2021-01-01“…Sequencing (or microarray) data and clinicopathological details of patients with RC were retrieved from The Cancer Genome Atlas (TCGA-READ) or the Gene Expression Omnibus (GSE123390, GSE56699) database. A weighted gene coexpression network was used to identify RC-related modules. …”
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7640
Blockchain-Based Value-Added Tax System: A Systematic Review
Published 2024-06-01“…By identifying existing challenges in electronic invoices, such as transaction forgery, the long process of issuing electronic invoices, and hacking of the central database, blockchain technology, with its features like decentralization, tamper-proofness, transparency, and automation, emerges as a suitable solution. …”
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