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7561
The Application of Machine Learning Algorithms to Predict HIV Testing in Repeated Adult Population–Based Surveys in South Africa: Protocol for a Multiwave Cross-Sectional Analysis...
Published 2025-01-01“…ResultsThe SABSSM datasets are open access datasets available on the HSRC database. Ethics approval for this study was obtained from the University of Johannesburg Research and Ethics Committee on April 23, 2024 (REC-2725-2024). …”
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7562
Exploring the Impact of Systemic Inflammatory Regulators on Rosacea Risk: A Bidirectional Mendelian Randomization Analysis
Published 2025-01-01“…This study employed a two-sample bidirectional Mendelian randomization (MR) analysis to investigate the causal links between systemic inflammatory regulators and rosacea.Methods: Data on 41 cytokines and growth factors were analyzed from a genome-wide association study (GWAS) meta-analysis involving 8293 individuals and genetic data from the FinnGen database, comprising 1195 rosacea cases and 211,139 controls. …”
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7563
Association between various blood glucose variability-related indicators during early ICU admission and 28-day mortality in non-diabetic patients with sepsis
Published 2025-01-01“…Methods The single-center retrospective cohort study included 7,049 non-diabetic adults with sepsis who had at least 3 records of bedside capillary point of care BG testing during the first day after ICU admission from MIMIC-IV database (2008 to 2019). Coefficient of variation and standard deviation of glucose (i.e., GluCV and GluSD), M-value, J-index, high blood glucose index (HBGI), and low blood glucose index (LBGI) were used to describe glucose variability, quality of glycemic control, and glycemic risk of patients with sepsis. …”
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7564
Occupational outcomes of people with multiple sclerosis: a scoping review
Published 2022-07-01“…Objectives To update the knowledge on the occupational outcomes associated with multiple sclerosis (MS), systematically examine the extent, scope and nature of the pre-existing literature and identify research gaps in the existing literature.Design Scoping review.Data sources A comprehensive database search of PubMed/MEDLINE, Scopus, SciVerse ScienceDirect and Web of Science was performed. …”
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7565
Longitudinal performance trajectories for youth female and male soccer players: 10m-sprint percentile curves adapted to biological age
Published 2025-01-01“…These data were extracted from the Swiss Football Association’s online database, covering the period from 2014, respectively 2019 to 2024. …”
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7566
Six-Gene Signature Associated with Immune Cells in the Progression of Atherosclerosis Discovered by Comprehensive Bioinformatics Analyses
Published 2020-01-01“…Methods. 29 samples of atherosclerosis-related gene expression profiling, including 16 human advanced atherosclerosis plaque (AA) and 13 human early atherosclerosis plaque (EA) samples from the Gene Expression Omnibus (GEO) database, were analyzed to get differentially expressed genes (DEGs) and the construction of protein and protein interaction (PPI) networks. …”
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7567
The necroptosis-related lncRNA ENSG00000253385.1 promotes the progression of esophageal squamous cell carcinoma by targeting the miR-16-2-3p/VDAC1 axis
Published 2025-01-01“…The binding sites between miR-16-2-3p and lncRNA ENSG00000253385.1 or voltage-dependent anion channel 1 (VDAC1) were predicted by bioinformatics database and confirmed by dual luciferase reporter gene assay. …”
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7568
GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway
Published 2025-01-01“…Methods Human ovarian tissue specimens, RNA sequencing, GEPIA database and bioinformatics analyses were used to analyze the gene correlation, and to identify and validate potential downstream candidates. …”
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7569
Genetic Biomarkers and Circulating White Blood Cells in Osteoarthritis: A Bioinformatics and Mendelian Randomization Analysis
Published 2025-01-01“…<b>Methods</b>: This study integrated transcriptome data from the GEO database with bioinformatics analyses to identify biomarkers associated with OA. …”
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7570
Correlation between Quantitative 13C-Urea Breath Test and Helicobacter pylori Treatment Success in a Population-Based Cohort
Published 2018-01-01“…Data were extracted from the Clalit Health Services laboratory database. Results. A total of 94,590 subjects (36.1% male, age 28.5 ± 6.0 years) who underwent a first-time C13-UBT during the study period were included. …”
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Folic acid supplementation in European women of reproductive age and during pregnancy with excessive weight: a systematic review
Published 2025-01-01“…Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. An electronic database search of manuscripts was carried out in Web of Sciences, PubMed and Medline. …”
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7572
Non-Pharmaceutical Interventions May Attenuate Acute Exacerbations of Asthma: Experience During the COVID-19 Pandemic in Taiwan
Published 2025-01-01“…Chun-Yu Lin,1,2 Chiung-Hung Lin,1,2 Yu-Lun Lo,1,2 Chun-Yu Lo,1,2 Hung-Yu Huang,1,2 Meng-Heng Hsieh,1,2 Yueh-Fu Fang,1,2 Tsu-Chuan Li,1,2 Shu-Min Lin,1,2 Yu-Tung Huang,3 Po-Jui Chang,1,2 Horng-Chyuan Lin1,2,4 1Department of Thoracic Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; 2College of Medicine Chang Gung University, Taoyuan, Taiwan; 3Center for Big Data Analytics and Statistics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 4Department of Respiratory Therapy, Chang Gung Memorial Hospital at Linkou, Taoyuan, TaiwanCorrespondence: Horng-Chyuan Lin, Department of Thoracic Medicine, Chang Gung Memorial Hospital, 5 Fu-Hsing Street, Kweishan, Taoyuan, 33305, Taiwan, Tel +886-3-3281200 ext. 8470, Fax +886-3-3282474, Email lin53424@gmail.comBackground: Non-pharmaceutical interventions (NPIs) were widely used during the coronavirus disease 2019 (COVID-19) pandemic, however their impact on acute asthma exacerbations (AEs) is not well studied.Methods: We had retrospectively collected patients with asthma AEs between 2019 and 2020 and retrieved data from the Chang Gung Research Database, including clinical manifestations, medications, pulmonary function, clinic and emergency department visits and hospitalizations.Results: A total of 39,108 adult patients with asthma were enrolled, of whom 1502 were eligible for analysis. …”
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Exploring the role of inflammatory biomarkers in trigeminal neuralgia
Published 2025-02-01“…Methods: A two-sample MR approach was employed using genome-wide association study (GWAS) data from 8293 Finnish individuals for inflammatory cytokines and data from the FinnGen database for TN. Instrumental variables (IVs) were selected based on genome-wide significance and clumping thresholds to avoid linkage disequilibrium. …”
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7574
Novel models based on machine learning to predict the prognosis of metaplastic breast cancer
Published 2025-02-01“…Methods: This study utilized patient data from the SEER database (2010–2018) for data analysis. We utilized prognostic factors to develop a novel machine learning model (CatBoost) for predicting patient survival rates. …”
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Interleukin-12 Inhibits Tumor Growth and Metastasis Promoted by Tumor-Associated Mesenchymal Stem Cells in Triple-Negative Breast Cancer
Published 2024-09-01“…The TA-MSCs RNA-seq dataset (PRJEB27694) was analyzed todetect elevated metastasis-associated oncogenes, downloaded from the European Nucleotide Archive database. Forvalidation of the RNA-seq data analysis, the expression levels of candidate oncogenes were evaluated in TA-MSCs,TNBC cells, and tumor tissue using RT-PCR.Results: TA-MSCs enhanced migration, invasion, and EMT of TNBC cells in vitro without affecting cell proliferation orapoptosis. …”
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Penerapan Metode K-Medoids untuk Pengelompokan Mahasiswa Berpotensi Drop Out
Published 2023-02-01“…Data mining analyzes data that already exists in the database to solve problems. One of the analyzes carried out is the clustering method. …”
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Sport values and sustainability?
Published 2025-01-01“…Methods Following PRISMA guidelines, we conducted a systematic review through Google Scholar, Semantic Scholar, and ERIC database using values of sport, sport values, sporting values, and athletic values keywords (n=7992). 32 studies published between 1990 and 2023 were retained. …”
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Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation
Published 2025-01-01“…Methods Firstly, the network pharmacology was used to screen the RosA targets, and LUAD-related differential expressed genes (DEGs) were acquired from the GEO database. The intersection of LUAD regulated by RosA (RDEGs) was obtained through the Venn diagram. …”
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7579
The association between the interval from biopsy to radical prostatectomy and biochemical recurrence in patients with intermediate- and high-risk prostate cancer
Published 2025-02-01“…ObjectiveTo investigate the association between the interval from biopsy to radical prostatectomy (RP) and biochemical recurrence (BCR) in prostate cancer patients.MethodsWithin a tertiary-care database (01/2014 to 06/2023), D’Amico intermediate- and high-risk prostate cancer patients were stratified according to interval from biopsy to RP (≤3 vs. …”
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Incidence of shoulder dislocations in the UK, 1995–2015: a population-based cohort study
Published 2017-11-01“…Incidence in women increased with age to a peak of 28.6 per 100 000 person-years among those aged 61–70 years.Conclusions This is the first time the incidence of shoulder dislocations has been studied using primary care data from a national database, and the first time the results for the UK have been produced. …”
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